Works by Marttila, Saara

Results: 27

Aging-associated patterns in the expression of human endogenous retroviruses.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0207407

By:

Nevalainen, Tapio;
Autio, Arttu;
Mishra, Binisha Hamal;
Marttila, Saara;
Jylhä, Marja;
Hurme, Mikko

Publication type:

Article

Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: the Vitality 90+ Study.

Published in:

BMC Medical Genomics, 2014, v. 7, n. 1, p. 54, doi. 10.1186/1755-8794-7-54

By:

Jylhävä, Juulia;
Raitanen, Jani;
Marttila, Saara;
Hervonen, Antti;
Jylhä, Marja;
Hurme, Mikko

Publication type:

Article

Molecular mechanisms associated with the strength of the anti-CMV response in nonagenarians.

Published in:

Immunity & Ageing, 2014, v. 11, p. 1, doi. 10.1186/1742-4933-11-2

By:

Marttila, Saara;
Jylhävä, Juulia;
Kananen, Laura;
Hervonen, Antti;
Jylhä, Marja;
Hurme, Mikko

Publication type:

Article

Biological aging of different blood cell types.

Published in:

GeroScience, 2025, v. 47, n. 1, p. 1075, doi. 10.1007/s11357-024-01287-w

By:

Marttila, Saara;
Rajić, Sonja;
Ciantar, Joanna;
Mak, Jonathan K. L.;
Junttila, Ilkka S.;
Kummola, Laura;
Hägg, Sara;
Raitoharju, Emma;
Kananen, Laura

Publication type:

Article

Early resilience and epigenetic ageing: Results from the prospective Young Finns Study with a 31‐year follow‐up.

Published in:

Aging Cell, 2025, v. 24, n. 2, p. 1, doi. 10.1111/acel.14394

By:

Saarinen, Aino;
Marttila, Saara;
Mishra, Pashupati P.;
Lyytikäinen, Leo‐Pekka;
Hamal Mishra, Binisha;
Raitoharju, Emma;
Mononen, Nina;
Kähönen, Mika;
Raitakari, Olli;
Lehtimäki, Terho;
Keltikangas‐Järvinen, Liisa

Publication type:

Article

NMR metabolomic modeling of age and lifespan: A multicohort analysis.

Published in:

Aging Cell, 2024, v. 23, n. 7, p. 1, doi. 10.1111/acel.14164

By:

Lau, Chung‐Ho E.;
Manou, Maria;
Markozannes, Georgios;
Ala‐Korpela, Mika;
Ben‐Shlomo, Yoav;
Chaturvedi, Nish;
Engmann, Jorgen;
Gentry‐Maharaj, Aleksandra;
Herzig, Karl‐Heinz;
Hingorani, Aroon;
Järvelin, Marjo‐Riitta;
Kähönen, Mika;
Kivimäki, Mika;
Lehtimäki, Terho;
Marttila, Saara;
Menon, Usha;
Munroe, Patricia B.;
Palaniswamy, Saranya;
Providencia, Rui;
Raitakari, Olli

Publication type:

Article

Polygenic risk for schizophrenia, social dispositions, and pace of epigenetic aging: Results from the Young Finns Study.

Published in:

Aging Cell, 2024, v. 23, n. 3, p. 1, doi. 10.1111/acel.14052

By:

Saarinen, Aino;
Marttila, Saara;
Mishra, Pashupati P.;
Lyytikäinen, Leo‐Pekka;
Raitoharju, Emma;
Mononen, Nina;
Sormunen, Elina;
Kähönen, Mika;
Raitakari, Olli;
Hietala, Jarmo;
Keltikangas‐Järvinen, Liisa;
Lehtimäki, Terho

Publication type:

Article

Transcriptional Analysis Reveals Gender-Specific Changes in the Aging of the Human Immune System.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066229

By:

Marttila, Saara;
Jylhävä, Juulia;
Nevalainen, Tapio;
Nykter, Matti;
Jylhä, Marja;
Hervonen, Antti;
Tserel, Liina;
Peterson, Pärt;
Hurme, Mikko

Publication type:

Article

Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait loci.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 10, p. 1720, doi. 10.1093/hmg/ddab339

By:

Laaksonen, Jaakko;
Mishra, Pashupati P;
Seppälä, Ilkka;
Raitoharju, Emma;
Marttila, Saara;
Mononen, Nina;
Lyytikäinen, Leo-Pekka;
Kleber, Marcus E;
Delgado, Graciela E;
Lepistö, Maija;
Almusa, Henrikki;
Ellonen, Pekka;
Lorkowski, Stefan;
März, Winfried;
Hutri-Kähönen, Nina;
Raitakari, Olli;
Kähönen, Mika;
Salonen, Jukka T;
Lehtimäki, Terho

Publication type:

Article

Ageing-associated changes in DNA methylation in X and Y chromosomes.

Published in:

Epigenetics & Chromatin, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13072-021-00407-6

By:

Kananen, Laura;
Marttila, Saara

Publication type:

Article

Number of sons contributes to ageing-associated inflammation.

Published in:

Scientific Reports, 2015, p. 8631, doi. 10.1038/srep08631

By:

Marttila, Saara;
Nevalainen, Tapio;
Kananen, Laura;
Jylhävä, Juulia;
Jylhä, Marja;
Hervonen, Antti;
Ilonen, Jorma;
Hurme, Mikko

Publication type:

Article

Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167028

By:

Nevalainen, Tapio;
Kananen, Laura;
Marttila, Saara;
Jylhävä, Juulia;
Jylhä, Marja;
Hervonen, Antti;
Hurme, Mikko

Publication type:

Article

Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88465-4

By:

Marttila, Saara;
Rovio, Suvi;
Mishra, Pashupati P.;
Seppälä, Ilkka;
Lyytikäinen, Leo-Pekka;
Juonala, Markus;
Waldenberger, Melanie;
Oksala, Niku;
Ala-Korpela, Mika;
Harville, Emily;
Hutri-Kähönen, Nina;
Kähönen, Mika;
Raitakari, Olli;
Lehtimäki, Terho;
Raitoharju, Emma

Publication type:

Article

Modular genome-wide gene expression architecture shared by early traits of osteoporosis and atherosclerosis in the Young Finns Study.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86536-0

By:

Mishra, Binisha H.;
Mishra, Pashupati P.;
Raitoharju, Emma;
Marttila, Saara;
Mononen, Nina;
Sievänen, Harri;
Viikari, Jorma;
Juonala, Markus;
Laaksonen, Marika;
Hutri-Kähönen, Nina;
Kähönen, Mika;
Raitakari, Olli T.;
Lehtimäki, Terho

Publication type:

Article

Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals.

Published in:

Clinical Epigenetics, 2017, v. 9, p. 1, doi. 10.1186/s13148-016-0301-7

By:

Nevalainen, Tapio;
Kananen, Laura;
Marttila, Saara;
Jylhävä, Juulia;
Mononen, Nina;
Kähönen, Mika;
Raitakari, Olli T.;
Hervonen, Antti;
Jylhä, Marja;
Lehtimäki, Terho;
Hurme, Mikko

Publication type:

Article

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1381-z

By:

Marttila, Saara;
Kananen, Laura;
Häyrynen, Sergei;
Jylhävä, Juulia;
Nevalainen, Tapio;
Hervonen, Antti;
Jylhä, Marja;
Nykter, Matti;
Hurme, Mikko

Publication type:

Article

Reproductive history and blood cell DNA methylation later in life: the Young Finns Study.

Published in:

Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01215-1

By:

Harville, Emily W.;
Mishra, Pashupati P.;
Kähönen, Mika;
Raitoharju, Emma;
Marttila, Saara;
Raitakari, Olli;
Lehtimäki, Terho

Publication type:

Article

Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs.

Published in:

Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01132-3

By:

Marttila, Saara;
Viiri, Leena E.;
Mishra, Pashupati P.;
Kühnel, Brigitte;
Matias-Garcia, Pamela R.;
Lyytikäinen, Leo-Pekka;
Ceder, Tiina;
Mononen, Nina;
Rathmann, Wolfgang;
Winkelmann, Juliane;
Peters, Annette;
Kähönen, Mika;
Hutri-Kähönen, Nina;
Juonala, Markus;
Aalto-Setälä, Katriina;
Raitakari, Olli;
Lehtimäki, Terho;
Waldenberger, Melanie;
Raitoharju, Emma

Publication type:

Article

Epigenome-450K-wide methylation signatures of active cigarette smoking: The Young Finns Study.

Published in:

Bioscience Reports, 2020, v. 40, n. 7, p. 1, doi. 10.1042/BSR20200596

By:

Mishra, Pashupati P.;
Hänninen, Ismo;
Raitoharju, Emma;
Marttila, Saara;
Mishra, Binisha H.;
Mononen, Nina;
KahÖnen, Mika;
Hurme, Mikko;
Raitakari, Ollix;
ToÖroÖnen, Petri;
Holm, Liisa;
Lehtimaki, Terho

Publication type:

Article

Sleep disturbances, shift work, and epigenetic ageing in working-age adults: findings from the Young Finns study.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01860-w

By:

Autio, Ida;
Saarinen, Aino;
Marttila, Saara;
Raitoharju, Emma;
Mishra, Pashupati P.;
Mononen, Nina;
Kähönen, Mika;
Keltikangas-Järvinen, Liisa;
Raitakari, Olli;
Lehtimäki, Terho

Publication type:

Article

Commentary on "Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth".

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-024-02220-7

By:

Raitoharju, Emma;
Marttila, Saara

Publication type:

Article

Androgen receptor overexpression alters binding dynamics of the receptor to chromatin and chromatin structure.

Published in:

Prostate, 2012, v. 72, n. 11, p. 1223, doi. 10.1002/pros.22473

By:

Urbanucci, Alfonso;
Marttila, Saara;
Jänne, Olli A.;
Visakorpi, Tapio

Publication type:

Article

Methylation pattern of polymorphically imprinted nc886 is not conserved across mammalia.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0261481

By:

Kostiniuk, Daria;
Tamminen, Hely;
Mishra, Pashupati P.;
Marttila, Saara;
Raitoharju, Emma

Publication type:

Article

Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty.

Published in:

Aging Cell, 2013, v. 12, n. 3, p. 388, doi. 10.1111/acel.12058

By:

Jylhävä, Juulia;
Nevalainen, Tapio;
Marttila, Saara;
Jylhä, Marja;
Hervonen, Antti;
Hurme, Mikko

Publication type:

Article

The relationship of trait-like compassion with epigenetic aging: The population-based prospective Young Finns Study.

Published in:

Frontiers in Psychiatry, 2023, p. 1, doi. 10.3389/fpsyt.2023.1018797

By:

Dobewall, Henrik;
Keltikangas-Järvinen, Liisa;
Marttila, Saara;
Mishra, Pashupati P.;
Saarinen, Aino;
Cloninger, C. Robert;
Zwir, Igor;
Kähönen, Mika;
Hurme, Mikko;
Raitakari, Olli;
Lehtimäki, Terho;
Hintsanen, Mirka

Publication type:

Article

Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns.

Published in:

Epigenetics, 2024, v. 19, n. 1, p. 1, doi. 10.1080/15592294.2024.2397297

By:

Ciantar, Joanna;
Marttila, Saara;
Rajić, Sonja;
Kostiniuk, Daria;
Mishra, Pashupati P;
Lyytikäinen, Leo-Pekka;
Mononen, Nina;
Kleber, Marcus E;
März, Winfried;
Kähönen, Mika;
Raitakari, Olli;
Lehtimäki, Terho;
Raitoharju, Emma

Publication type:

Article

Non-coding 886 (nc886/vtRNA2-1), the epigenetic odd duck – implications for future studies.

Published in:

Epigenetics, 2024, v. 19, n. 1, p. 1, doi. 10.1080/15592294.2024.2332819

By:

Raitoharju, Emma;
Rajić, Sonja;
Marttila, Saara

Publication type:

Article