Works matching AU Martincorena, Inigo

Results: 32

Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29920-2

By:

Lee, Bernard C. H.;
Robinson, Philip S.;
Coorens, Tim H. H.;
Yan, Helen H. N.;
Olafsson, Sigurgeir;
Lee-Six, Henry;
Sanders, Mathijs A.;
Siu, Hoi Cheong;
Hewinson, James;
Yue, Sarah S. K.;
Tsui, Wai Yin;
Chan, Annie S. Y.;
Chan, Anthony K. W.;
Ho, Siu Lun;
Campbell, Peter J.;
Martincorena, Inigo;
Buczacki, Simon J. A.;
Yuen, Siu Tsan;
Leung, Suet Yi;
Stratton, Michael R.

Publication type:

Article

Lexical access changes in patients with multiple sclerosis: A two-year follow-up study.

Published in:

Journal of Clinical & Experimental Neuropsychology, 2011, v. 33, n. 2, p. 169, doi. 10.1080/13803395.2010.499354

By:

Sepulcre, Jorge;
Peraita, Herminia;
Goñi, Joaquín;
Arrondo, Gonzalo;
Martincorena, Iñigo;
Duque, Beatriz;
Vélez de Mendizábal, Nieves;
Masdeu, JosephC.;
Villoslada, Pablo

Publication type:

Article

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.

Published in:

Nature Genetics, 2014, v. 46, n. 2, p. 116, doi. 10.1038/ng.2874

By:

Papaemmanuil, Elli;
Rapado, Inmaculada;
Li, Yilong;
Potter, Nicola E;
Wedge, David C;
Tubio, Jose;
Alexandrov, Ludmil B;
Van Loo, Peter;
Cooke, Susanna L;
Marshall, John;
Martincorena, Inigo;
Hinton, Jonathan;
Gundem, Gunes;
van Delft, Frederik W;
Nik-Zainal, Serena;
Jones, David R;
Ramakrishna, Manasa;
Titley, Ian;
Stebbings, Lucy;
Leroy, Catherine

Publication type:

Article

Recurrent PTPRB and PLCG1 mutations in angiosarcoma.

Published in:

Nature Genetics, 2014, v. 46, n. 4, p. 376, doi. 10.1038/ng.2921

By:

Behjati, Sam;
Tarpey, Patrick S;
Sheldon, Helen;
Martincorena, Inigo;
Van Loo, Peter;
Gundem, Gunes;
Wedge, David C;
Ramakrishna, Manasa;
Cooke, Susanna L;
Pillay, Nischalan;
Vollan, Hans Kristian M;
Papaemmanuil, Elli;
Koss, Hans;
Bunney, Tom D;
Hardy, Claire;
Joseph, Olivia R;
Martin, Sancha;
Mudie, Laura;
Butler, Adam;
Teague, Jon W

Publication type:

Article

Inactivating CUX1 mutations promote tumorigenesis.

Published in:

Nature Genetics, 2014, v. 46, n. 1, p. 33, doi. 10.1038/ng.2846

By:

Wong, Chi C;
Martincorena, Inigo;
Rust, Alistair G;
Rashid, Mamunur;
Alifrangis, Constantine;
Alexandrov, Ludmil B;
Tiffen, Jessamy C;
Kober, Christina;
Green, Anthony R;
Massie, Charles E;
Nangalia, Jyoti;
Lempidaki, Stella;
Döhner, Hartmut;
Döhner, Konstanze;
Bray, Sarah J;
McDermott, Ultan;
Papaemmanuil, Elli;
Campbell, Peter J;
Adams, David J

Publication type:

Article

Patterns of within-host genetic diversity in SARS-CoV-2.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.66857

By:

Tonkin-Hill, Gerry;
Martincorena, Inigo;
Amato, Roberto;
Lawson, Andrew R. J.;
Gerstrung, Moritz;
Johnston, Ian;
Jackson, David K.;
Park, Naomi;
Lensing, Stefanie V.;
Quail, Michael A.;
Gonc¸alves, Sonia;
Ariani, Cristina;
Chapman, Michael Spencer;
Hamilton, William L.;
Meredith, Luke W.;
Hall, Grant;
Jahun, Aminu S.;
Chaudhry, Yasmin;
Hosmillo, Myra;
Pinckert, Malte L.

Publication type:

Article

Reconstructing phylogenetic trees from genome-wide somatic mutations in clonal samples.

Published in:

Nature Protocols, 2024, v. 19, n. 6, p. 1866, doi. 10.1038/s41596-024-00962-8

By:

Coorens, Tim H. H.;
Spencer Chapman, Michael;
Williams, Nicholas;
Martincorena, Inigo;
Stratton, Michael R.;
Nangalia, Jyoti;
Campbell, Peter J.

Publication type:

Article

Author Correction: Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing.

Published in:

2023

By:

Ellis, Peter;
Moore, Luiza;
Sanders, Mathijs A.;
Butler, Timothy M.;
Brunner, Simon F.;
Lee-Six, Henry;
Osborne, Robert;
Farr, Ben;
Coorens, Tim H. H.;
Lawson, Andrew R. J.;
Cagan, Alex;
Stratton, Mike R.;
Martincorena, Inigo;
Campbell, Peter J.

Publication type:

Correction Notice

Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing.

Published in:

Nature Protocols, 2021, v. 16, n. 2, p. 841, doi. 10.1038/s41596-020-00437-6

By:

Ellis, Peter;
Moore, Luiza;
Sanders, Mathijs A.;
Butler, Timothy M.;
Brunner, Simon F.;
Lee-Six, Henry;
Osborne, Robert;
Farr, Ben;
Coorens, Tim H. H.;
Lawson, Andrew R. J.;
Cagan, Alex;
Stratton, Mike R.;
Martincorena, Inigo;
Campbell, Peter J.

Publication type:

Article

GOTHiC, a probabilistic model to resolve complex biases and to identify real interactions in Hi-C data.

Published in:

PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0174744

By:

Martincorena, Inigo;
Darbo, Elodie;
Sugar, Robert;
Mifsud, Borbala;
Luscombe, Nicholas M.;
Schoenfelder, Stefan;
Fraser, Peter

Publication type:

Article

Non-random mutation: The evolution of targeted hypermutation and hypomutation.

Published in:

BioEssays, 2013, v. 35, n. 2, p. 123, doi. 10.1002/bies.201200150

By:

Martincorena, Iñigo;
Luscombe, Nicholas M.

Publication type:

Article

Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids.

Published in:

BMC Developmental Biology, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12861-020-0209-5

By:

Georgakopoulos, Nikitas;
Prior, Nicole;
Angres, Brigitte;
Mastrogiovanni, Gianmarco;
Cagan, Alex;
Harrison, Daisy;
Hindley, Christopher J.;
Arnes-Benito, Robert;
Liau, Siong-Seng;
Curd, Abbie;
Ivory, Natasha;
Simons, Benjamin D.;
Martincorena, Inigo;
Wurst, Helmut;
Saeb-Parsy, Kourosh;
Huch, Meritxell

Publication type:

Article

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31659-0

By:

Collord, Grace;
Tarpey, Patrick;
Kurbatova, Natalja;
Martincorena, Inigo;
Moran, Sebastian;
Castro, Manuel;
Nagy, Tibor;
Bignell, Graham;
Maura, Francesco;
Young, Matthew D.;
Berna, Jorge;
Tubio, Jose M. C.;
McMurran, Chris E.;
Young, Adam M. H.;
Sanders, Mathijs;
Noorani, Imran;
Price, Stephen J.;
Watts, Colin;
Leipnitz, Elke;
Kirsch, Matthias

Publication type:

Article

Pathway-based dissection of the genomic heterogeneity of cancer hallmarks' acquisition with SLAPenrich.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-25076-6

By:

Iorio, Francesco;
Garcia-Alonso, Luz;
Brammeld, Jonathan S.;
Martincorena, Iňigo;
Wille, David R.;
McDermott, Ultan;
Saez-Rodriguez, Julio

Publication type:

Article

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.

Published in:

Nature Communications, 2017, v. 8, n. 6, p. 15936, doi. 10.1038/ncomms15936

By:

Behjati, Sam;
Tarpey, Patrick S.;
Haase, Kerstin;
Ye, Hongtao;
Young, Matthew D.;
Alexandrov, Ludmil B.;
Farndon, Sarah J.;
Collord, Grace;
Wedge, David C.;
Martincorena, Inigo;
Cooke, Susanna L.;
Davies, Helen;
Mifsud, William;
Lidgren, Mathias;
Martin, Sancha;
Latimer, Calli;
Maddison, Mark;
Butler, Adam P.;
Teague, Jon W.;
Pillay, Nischalan

Publication type:

Article

Processed pseudogenes acquired somatically during cancer development.

Published in:

Nature Communications, 2014, v. 5, n. 4, p. 3644, doi. 10.1038/ncomms4644

By:

Cooke, Susanna L.;
Shlien, Adam;
Marshall, John;
Pipinikas, Christodoulos P.;
Martincorena, Inigo;
Tubio, Jose M.C.;
Li, Yilong;
Menzies, Andrew;
Mudie, Laura;
Ramakrishna, Manasa;
Yates, Lucy;
Davies, Helen;
Bolli, Niccolo;
Bignell, Graham R.;
Tarpey, Patrick S.;
Behjati, Sam;
Nik-Zainal, Serena;
Papaemmanuil, Elli;
Teixeira, Vitor H.;
Raine, Keiran

Publication type:

Article

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.

Published in:

Nature Communications, 2014, v. 5, n. 1, p. 2997, doi. 10.1038/ncomms3997

By:

Bolli, Niccolo;
Avet-Loiseau, Hervé;
Wedge, David C.;
Van Loo, Peter;
Alexandrov, Ludmil B.;
Martincorena, Inigo;
Dawson, Kevin J.;
Iorio, Francesco;
Nik-Zainal, Serena;
Bignell, Graham R.;
Hinton, Jonathan W.;
Li, Yilong;
Tubio, Jose M.C.;
McLaren, Stuart;
O' Meara, Sarah;
Butler, Adam P.;
Teague, Jon W.;
Mudie, Laura;
Anderson, Elizabeth;
Rashid, Naim

Publication type:

Article

Somatic mutation and clonal expansions in human tissues.

Published in:

Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0648-4

By:

Martincorena, Inigo

Publication type:

Article

The Organization of Local and Distant Functional Connectivity in the Human Brain.

Published in:

PLoS Computational Biology, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.pcbi.1000808

By:

Sepulcre, Jorge;
Hesheng Liu;
Talukdar, Tanveer;
Martincorena, Iñigo;
Thomas Yeo, B. T.;
Buckner, Randy L.

Publication type:

Article

Genomic patterns of progression in smoldering multiple myeloma.

Published in:

Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05058-y

By:

Bolli, Niccolò;
Maura, Francesco;
Minvielle, Stephane;
Gloznik, Dominik;
Szalat, Raphael;
Fullam, Anthony;
Martincorena, Inigo;
Dawson, Kevin J.;
Samur, Mehmet Kemal;
Zamora, Jorge;
Tarpey, Patrick;
Davies, Helen;
Fulciniti, Mariateresa;
Shammas, Masood A.;
Yu Tzu Tai;
Magrangeas, Florence;
Moreau, Philippe;
Corradini, Paolo;
Anderson, Kenneth;
Alexandrov, Ludmil

Publication type:

Article

The driver landscape of sporadic chordoma.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01026-0

By:

Tarpey, Patrick S.;
Behjati, Sam;
Young, Matthew D.;
Martincorena, Inigo;
Alexandrov, Ludmil B.;
Farndon, Sarah J.;
Guzzo, Charlotte;
Hardy, Claire;
Latimer, Calli;
Butler, Adam P.;
Teague, Jon W.;
Shlien, Adam;
Futreal, P. Andrew;
Shah, Sohrab;
Bashashati, Ali;
Jamshidi, Farzad;
Nielsen, Torsten O.;
Huntsman, David;
Baumhoer, Daniel;
Brandner, Sebastian

Publication type:

Article

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.

Published in:

Genome Biology, 2013, v. 14, n. 10, p. 3, doi. 10.1186/gb-2013-14-10-r113

By:

Yen, Jennifer;
White, Richard M.;
Wedge, David C.;
Loo, Peter Van;
Ridder, Jeroen de;
Capper, Amy;
Richardson, Jennifer;
Jones, David;
Raine, Keiran;
Watson, Ian R.;
Chang-Jiun Wu;
Jiqiu Cheng;
Martincorena, Iñigo;
Nik-Zainal, Serena;
Mudie, Laura;
Moreau, Yves;
Marshall, John;
Ramakrishna, Manasa;
Tarpey, Patrick;
Shlien, Adam

Publication type:

Article

SWITCHER-RANDOM-WALKS:: A COGNITIVE-INSPIRED MECHANISM FOR NETWORK EXPLORATION.

Published in:

International Journal of Bifurcation & Chaos in Applied Sciences & Engineering, 2010, v. 20, n. 3, p. 913, doi. 10.1142/S0218127410026204

By:

GOÑI, JOAQUÍN;
MARTINCORENA, IÑIGO;
COROMINAS-MURTRA, BERNAT;
ARRONDO, GONZALO;
ARDANZA-TREVIJANO, SERGIO;
VILLOSLADA, PABLO

Publication type:

Article

Recurrent histone mutations in T‐cell acute lymphoblastic leukaemia.

Published in:

British Journal of Haematology, 2019, v. 184, n. 4, p. 676, doi. 10.1111/bjh.15155

By:

Collord, Grace;
Martincorena, Inigo;
Young, Matthew D.;
Foroni, Letizia;
Bolli, Niccolo;
Stratton, Michael R.;
Vassiliou, George S.;
Campbell, Peter J.;
Behjati, Sam

Publication type:

Article

Mutational signatures are jointly shaped by DNA damage and repair.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15912-7

By:

Volkova, Nadezda V.;
Meier, Bettina;
González-Huici, Víctor;
Bertolini, Simone;
Gonzalez, Santiago;
Vöhringer, Harald;
Abascal, Federico;
Martincorena, Iñigo;
Campbell, Peter J.;
Gartner, Anton;
Gerstung, Moritz

Publication type:

Article

The semantic organization of the animal category: evidence from semantic verbal fluency and network theory.

Published in:

2011

By:

Goñi, Joaquín;
Arrondo, Gonzalo;
Sepulcre, Jorge;
Martincorena, Iñigo;
Vélez de Mendizábal, Nieves;
Corominas-Murtra, Bernat;
Bejarano, Bartolomé;
Ardanza-Trevijano, Sergio;
Peraita, Herminia;
Wall, Dennis;
Villoslada, Pablo

Publication type:

Report

Evidence of non-random mutation rates suggests an evolutionary risk management strategy.

Published in:

Nature, 2012, v. 485, n. 7396, p. 95, doi. 10.1038/nature10995

By:

Martincorena, Iñigo;
Seshasayee, Aswin S. N.;
Luscombe, Nicholas M.

Publication type:

Article

Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology.

Published in:

Mutagenesis, 2023, v. 38, n. 4, p. 192, doi. 10.1093/mutage/gead012

By:

Lynch, Anthony M;
Zanoni, Thalita B;
Salk, Jesse J;
Martincorena, Inigo;
Young, Robert R;
Kucab, Jill;
Valentine, Charles C;
Yauk, Carole;
Escobar, Patricia A;
Witt, Kristine L;
Frötschl, Roland;
Reed, Simon H;
Ashford, Anne

Publication type:

Article

Genome sequencing of normal cells reveals developmental lineages and mutational processes.

Published in:

Nature, 2014, v. 513, n. 7518, p. 422, doi. 10.1038/nature13448

By:

Behjati, Sam;
Huch, Meritxell;
van Boxtel, Ruben;
Karthaus, Wouter;
Wedge, David C.;
Martincorena, Iñigo;
Petljak, Mia;
Alexandrov, Ludmil B.;
Gundem, Gunes;
Tarpey, Patrick S.;
Roerink, Sophie;
Maddison, Mark;
Mudie, Laura;
Robinson, Ben;
Campbell, Peter;
Stratton, Michael R.;
Tamuri, Asif U.;
Goldman, Nick;
Blokker, Joyce;
van de Wetering, Marc

Publication type:

Article

Genomic landscape and chronological reconstruction of driver events in multiple myeloma.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11680-1

By:

Maura, Francesco;
Bolli, Niccoló;
Angelopoulos, Nicos;
Dawson, Kevin J.;
Leongamornlert, Daniel;
Martincorena, Inigo;
Mitchell, Thomas J.;
Fullam, Anthony;
Gonzalez, Santiago;
Szalat, Raphael;
Abascal, Federico;
Rodriguez-Martin, Bernardo;
Samur, Mehmet Kemal;
Glodzik, Dominik;
Roncador, Marco;
Fulciniti, Mariateresa;
Tai, Yu Tzu;
Minvielle, Stephane;
Magrangeas, Florence;
Moreau, Philippe

Publication type:

Article

Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08081-1

By:

Wong, Kim;
van der Weyden, Louise;
Schott, Courtney R.;
Foote, Alastair;
Constantino-Casas, Fernando;
Smith, Sionagh;
Dobson, Jane M.;
Murchison, Elizabeth P.;
Wu, Hong;
Yeh, Iwei;
Fullen, Douglas R.;
Joseph, Nancy;
Bastian, Boris C.;
Patel, Rajiv M.;
Martincorena, Inigo;
Robles-Espinoza, Carla Daniela;
Iyer, Vivek;
Kuijjer, Marieke L.;
Arends, Mark J.;
Brenn, Thomas

Publication type:

Article

Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator.

Published in:

BMC Bioinformatics, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s12859-020-03772-3

By:

Bergstrom, Erik N.;
Barnes, Mark;
Martincorena, Iñigo;
Alexandrov, Ludmil B.

Publication type:

Article