Found: 25

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  • Levothyroxine enhances glucose clearance and blunts the onset of experimental type 1 diabetes mellitus in mice.

    Published in:
    2017
    By:
    • López ‐ Noriega, Livia;
    • Cobo ‐ Vuilleumier, Nadia;
    • Narbona ‐ Pérez, Álvaro Jesús;
    • Araujo ‐ Garrido, Juan Luis;
    • LorENzo, Petra Isabel;
    • Mellado ‐ Gil, José Manuel;
    • MorENo, José Carlos;
    • Gauthier, BENoit R;
    • Martín ‐ Montalvo, Alejandro;
    • López-Noriega, Livia;
    • Cobo-Vuilleumier, Nadia;
    • Narbona-Pérez, Álvaro Jesús;
    • Araujo-Garrido, Juan Luis;
    • Mellado-Gil, José Manuel;
    • Moreno, José Carlos;
    • Martín-Montalvo, Alejandro
    Publication type:
    journal article

  • PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.

    Published in:
    Diabetologia, 2016, v. 59, n. 4, p. 755, doi. 10.1007/s00125-016-3864-0
    By:
    • Mellado-Gil, José;
    • Jiménez-Moreno, Carmen;
    • Martin-Montalvo, Alejandro;
    • Alvarez-Mercado, Ana;
    • Fuente-Martin, Esther;
    • Cobo-Vuilleumier, Nadia;
    • Lorenzo, Petra;
    • Bru-Tari, Eva;
    • Gracia Herrera-Gómez, Irene;
    • López-Noriega, Livia;
    • Pérez-Florido, Javier;
    • Santoyo-López, Javier;
    • Spyrantis, Andreas;
    • Meda, Paolo;
    • Boehm, Bernhard;
    • Quesada, Ivan;
    • Gauthier, Benoit
    Publication type:
    Article

  • PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet.

    Published in:
    Scientific Reports, 2015, p. 15672, doi. 10.1038/srep15672
    By:
    • Lorenzo, Petra I.;
    • Fuente-Martín, Esther;
    • Brun, Thierry;
    • Cobo-Vuilleumier, Nadia;
    • Jimenez-Moreno, Carmen María;
    • G. Herrera Gomez, Irene;
    • López Noriega, Livia;
    • Mellado-Gil, José Manuel;
    • Martin-Montalvo, Alejandro;
    • Soria, Bernat;
    • Gauthier, Benoit R.
    Publication type:
    Article

  • Generation of mesenchymal stromal cells from urine-derived iPSCs of pediatric brain tumor patients.

    Published in:
    Frontiers in Immunology, 2023, v. 13, p. 1, doi. 10.3389/fimmu.2023.1022676
    By:
    • Baliña-Sánchez, Carmen;
    • Aguilera, Yolanda;
    • Adán, Norma;
    • María Sierra-Párraga, Jesús;
    • Olmedo-Moreno, Laura;
    • Panadero-Morón, Concepción;
    • Cabello-Laureano, Rosa;
    • Márquez-Vega, Catalina;
    • Martín-Montalvo, Alejandro;
    • Capilla-González, Vivian
    Publication type:
    Article

  • Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40596-0
    By:
    • Lluch, Aina;
    • Latorre, Jessica;
    • Serena-Maione, Angela;
    • Espadas, Isabel;
    • Caballano-Infantes, Estefanía;
    • Moreno-Navarrete, José M.;
    • Oliveras-Cañellas, Núria;
    • Ricart, Wifredo;
    • Malagón, María M.;
    • Martin-Montalvo, Alejandro;
    • Birchmeier, Walter;
    • Szymanski, Witold;
    • Graumann, Johannes;
    • Gómez-Serrano, María;
    • Sommariva, Elena;
    • Fernández-Real, José M.;
    • Ortega, Francisco J.
    Publication type:
    Article

  • The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.

    Published in:
    Cell Death & Disease, 2018, v. 9, n. 3, p. 1, doi. 10.1038/s41419-018-0272-z
    By:
    • Mellado-Gil, Jose M.;
    • Fuente-Martín, Esther;
    • Lorenzo, Petra I.;
    • Cobo-Vuilleumier, Nadia;
    • López-Noriega, Livia;
    • Martín-Montalvo, Alejandro;
    • Gómez, Irene de Gracia Herrera;
    • Ceballos-Chávez, Maria;
    • Gómez-Jaramillo, Laura;
    • Campos-Caro, Antonio;
    • Romero-Zerbo, Silvana Y.;
    • Rodríguez-Comas, Júlia;
    • Servitja, Joan-Marc;
    • Rojo-Martinez, Gemma;
    • Hmadcha, Abdelkrim;
    • Soria, Bernat;
    • Bugliani, Marco;
    • Marchetti, Piero;
    • Bérmudez-Silva, Francisco J.;
    • Reyes, Jose C.
    Publication type:
    Article

  • Metformin improves healthspan and lifespan in mice.

    Published in:
    Nature Communications, 2013, v. 4, n. 7, p. 2192, doi. 10.1038/ncomms3192
    By:
    • Martin-Montalvo, Alejandro;
    • Mercken, Evi M.;
    • Mitchell, Sarah J.;
    • Palacios, Hector H.;
    • Mote, Patricia L.;
    • Scheibye-Knudsen, Morten;
    • Gomes, Ana P.;
    • Ward, Theresa M.;
    • Minor, Robin K.;
    • Blouin, Marie-José;
    • Schwab, Matthias;
    • Pollak, Michael;
    • Zhang, Yongqing;
    • Yu, Yinbing;
    • Becker, Kevin G.;
    • Bohr, Vilhelm A.;
    • Ingram, Donald K.;
    • Sinclair, David A.;
    • Wolf, Norman S.;
    • Spindler, Stephen R.
    Publication type:
    Article

  • Transient Expression in Islets During Pregnancy Correlates With β-Cell Survival, Revealing a Novel Candidate Gene in Gestational Diabetes Mellitus.

    Published in:
    2019
    By:
    • Martin-Montalvo, Alejandro;
    • López-Noriega, Livia;
    • Jiménez-Moreno, Carmen;
    • Herranz, Amanda;
    • Lorenzo, Petra I.;
    • Cobo-Vuilleumier, Nadia;
    • Tamayo, Alejandra;
    • González-Guerrero, Cristian;
    • Hofsteede, Jonathan S. W. R.;
    • Lebreton, Fanny;
    • Bosco, Domenico;
    • García Toscano, Miguel;
    • Herranz, Lucrecia;
    • Anselmo, Joao;
    • Carlos Moreno, José;
    • Gauthier, Benoit R.;
    • Toscano, Miguel García;
    • Moreno, José Carlos
    Publication type:
    journal article

  • Laparoscopic Sleeve Gastrectomy in Patients with Severe Obesity Restores Adaptive Responses Leading to Nonalcoholic Steatohepatitis.

    Published in:
    International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7830, doi. 10.3390/ijms23147830
    By:
    • Cabré, Noemí;
    • Luciano-Mateo, Fedra;
    • Chapski, Douglas J.;
    • Baiges-Gaya, Gerard;
    • Fernández-Arroyo, Salvador;
    • Hernández-Aguilera, Anna;
    • Castañé, Helena;
    • Rodríguez-Tomàs, Elisabet;
    • París, Marta;
    • Sabench, Fàtima;
    • Castillo, Daniel Del;
    • del Bas, Josep M.;
    • Tomé, Mercedes;
    • Bodineau, Clément;
    • Sola-García, Alejandro;
    • López-Miranda, José;
    • Martín-Montalvo, Alejandro;
    • Durán, Raúl V.;
    • Vondriska, Thomas M.;
    • Rosa-Garrido, Manuel
    Publication type:
    Article

  • Molecular Modelling of Islet β-Cell Adaptation to Inflammation in Pregnancy and Gestational Diabetes Mellitus.

    Published in:
    International Journal of Molecular Sciences, 2019, v. 20, n. 24, p. 6171, doi. 10.3390/ijms20246171
    By:
    • Lorenzo, Petra I.;
    • Martín-Montalvo, Alejandro;
    • Cobo Vuilleumier, Nadia;
    • Gauthier, Benoit R.
    Publication type:
    Article

  • The Regulation of Coenzyme Q Biosynthesis in Eukaryotic Cells: All That Yeast Can Tell Us.

    Published in:
    Molecular Syndromology, 2014, v. 5, n. 3/4, p. 107, doi. 10.1159/000362897
    By:
    • González-Mariscal, Isabel;
    • García-Testón, Elena;
    • Padilla, Sergio;
    • Martín-Montalvo, Alejandro;
    • Pomares Viciana, Teresa;
    • Vazquez-Fonseca, Luis;
    • Gandolfo Domínguez, Pablo;
    • Santos-Ocaña, Carlos
    Publication type:
    Article

  • Dissecting the Brain/Islet Axis in Metabesity.

    Published in:
    Genes, 2019, v. 10, n. 5, p. 350, doi. 10.3390/genes10050350
    By:
    • Fuente-Martín, Esther;
    • Mellado-Gil, Jose M.;
    • Cobo-Vuilleumier, Nadia;
    • Martín-Montalvo, Alejandro;
    • Romero-Zerbo, Silvana Y.;
    • Diaz Contreras, Irene;
    • Hmadcha, Abdelkrim;
    • Soria, Bernat;
    • Martin Bermudo, Francisco;
    • Reyes, Jose C.;
    • Bermúdez-Silva, Francisco J.;
    • Lorenzo, Petra I.;
    • Gauthier, Benoit R.
    Publication type:
    Article

  • Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy.

    Published in:
    Frontiers in Cellular Neuroscience, 2019, p. N.PAG, doi. 10.3389/fncel.2019.00204
    By:
    • Soria, Bernat;
    • Martin-Montalvo, Alejandro;
    • Aguilera, Yolanda;
    • Mellado-Damas, Nuria;
    • López-Beas, Javier;
    • Herrera-Herrera, Isabel;
    • López, Escarlata;
    • Barcia, Juan A.;
    • Alvarez-Dolado, Manuel;
    • Hmadcha, Abdelkrim;
    • Capilla-González, Vivian
    Publication type:
    Article

  • Regulation of coenzyme Q biosynthesis in yeast: A new complex in the block.

    Published in:
    IUBMB Life, 2014, v. 66, n. 2, p. 63, doi. 10.1002/iub.1243
    By:
    • González‐Mariscal, Isabel;
    • García‐Testón, Elena;
    • Padilla, Sergio;
    • Martín‐Montalvo, Alejandro;
    • Pomares‐Viciana, Teresa;
    • Vazquez‐Fonseca, Luis;
    • Gandolfo‐Domínguez, Pablo;
    • Santos‐Ocaña, Carlos
    Publication type:
    Article

  • Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy.

    Published in:
    Science Translational Medicine, 2012, v. 4, n. 124, p. 1, doi. 10.1126/scitranslmed.3003293
    By:
    • Changhan Lee;
    • Raffaghello, Lizzia;
    • Brandhorst, Sebastian;
    • Safdie, Fernando M.;
    • Bianchi, Giovanna;
    • Martin-Montalvo, Alejandro;
    • Pistoia, Vito;
    • Min Wei;
    • Saewon Hwang;
    • Merlino, Annalisa;
    • Emionite, Laura;
    • de Cabo, Rafael;
    • Longo, Valter D.
    Publication type:
    Article

  • Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans.

    Published in:
    Science Translational Medicine, 2011, v. 3, n. 70, p. 1, doi. 10.1126/scitranslmed.3001845
    By:
    • Guevara-Aguirre, Jaime;
    • Balasubramanian, Priya;
    • Guevara-Aguirre, Marco;
    • Wei, Min;
    • Madia, Federica;
    • Cheng, Chia-Wei;
    • Hwang, David;
    • Martin-Montalvo, Alejandro;
    • Saavedra, Jannette;
    • Ingles, Sue;
    • Cabo, Rafael de;
    • Cohen, Pinchas;
    • Longo, Valter D.
    Publication type:
    Article

  • Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87761-3
    By:
    • Álvarez-Amor, Leticia;
    • Sierra, Amparo Luque;
    • Cárdenas, Antonio;
    • López-Bermudo, Lucía;
    • López-Beas, Javier;
    • Andújar, Eloísa;
    • Pérez-Alegre, Mónica;
    • Gallego-Durán, Rocío;
    • Varela, Lourdes M.;
    • Martin-Montalvo, Alejandro;
    • Berná, Genoveva;
    • Rojas, Anabel;
    • Robles-Frías, Mª José;
    • Hmadcha, Abdelkrim;
    • Romero-Gómez, Manuel;
    • Kleemann, Robert;
    • Martín, Franz
    Publication type:
    Article

  • The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity.

    Published in:
    Theranostics, 2021, v. 11, n. 14, p. 6983, doi. 10.7150/thno.57237
    By:
    • Lorenzo, Petra I.;
    • Martin Vazquez, Eugenia;
    • López-Noriega, Livia;
    • Fuente-Martín, Esther;
    • Mellado-Gil, José M.;
    • Franco, Jaime M.;
    • Cobo-Vuilleumier, Nadia;
    • Guerrero Martínez, José A.;
    • Romero-Zerbo, Silvana Y.;
    • Perez-Cabello, Jesús A.;
    • Rivero Canalejo, Sabrina;
    • Campos-Caro, Antonio;
    • Claude Lachaud, Christian;
    • Crespo Barreda, Alejandra;
    • Aguilar-Diosdado, Manuel;
    • García Fuentes, Eduardo;
    • Martin-Montalvo, Alejandro;
    • Álvarez Dolado, Manuel;
    • Martin, Franz;
    • Rojo-Martinez, Gemma
    Publication type:
    Article

  • Preclinical Safety Evaluation of Intranasally Delivered Human Mesenchymal Stem Cells in Juvenile Mice.

    Published in:
    Cancers, 2021, v. 13, n. 5, p. 1169, doi. 10.3390/cancers13051169
    By:
    • Aguilera, Yolanda;
    • Mellado-Damas, Nuria;
    • Olmedo-Moreno, Laura;
    • López, Víctor;
    • Panadero-Morón, Concepción;
    • Benito, Marina;
    • Guerrero-Cázares, Hugo;
    • Márquez-Vega, Catalina;
    • Martín-Montalvo, Alejandro;
    • Capilla-González, Vivian;
    • Bago, Juli
    Publication type:
    Article

  • Thyroid hormones in diabetes, cancer, and aging.

    Published in:
    Aging Cell, 2020, v. 19, n. 11, p. 1, doi. 10.1111/acel.13260
    By:
    • Gauthier, Benoit R.;
    • Sola‐García, Alejandro;
    • Cáliz‐Molina, María Ángeles;
    • Lorenzo, Petra Isabel;
    • Cobo‐Vuilleumier, Nadia;
    • Capilla‐González, Vivian;
    • Martin‐Montalvo, Alejandro
    Publication type:
    Article

  • Overexpression of CYB5R3 and NQO1, two NAD<sup>+</sup>‐producing enzymes, mimics aspects of caloric restriction.

    Published in:
    Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12767
    By:
    • Diaz‐Ruiz, Alberto;
    • Lanasa, Michael;
    • Garcia, Joseph;
    • Mora, Hector;
    • Fan, Frances;
    • Martin‐Montalvo, Alejandro;
    • Di Francesco, Andrea;
    • Calvo‐Rubio, Miguel;
    • Salvador‐Pascual, Andrea;
    • Aon, Miguel A.;
    • Fishbein, Kenneth W.;
    • Pearson, Kevin J.;
    • Villalba, Jose Manuel;
    • Navas, Placido;
    • Bernier, Michel;
    • de Cabo, Rafael
    Publication type:
    Article

  • Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence.

    Published in:
    Aging Cell, 2016, v. 15, n. 3, p. 572, doi. 10.1111/acel.12469
    By:
    • Noren Hooten, Nicole;
    • Martin‐Montalvo, Alejandro;
    • Dluzen, Douglas F.;
    • Zhang, Yongqing;
    • Bernier, Michel;
    • Zonderman, Alan B.;
    • Becker, Kevin G.;
    • Gorospe, Myriam;
    • Cabo, Rafael;
    • Evans, Michele K.
    Publication type:
    Article

  • SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.

    Published in:
    Aging Cell, 2014, v. 13, n. 5, p. 787, doi. 10.1111/acel.12220
    By:
    • Mercken, Evi M.;
    • Mitchell, Sarah J.;
    • Martin‐Montalvo, Alejandro;
    • Minor, Robin K.;
    • Almeida, Maria;
    • Gomes, Ana P.;
    • Scheibye‐Knudsen, Morten;
    • Palacios, Hector H.;
    • Licata, Jordan J.;
    • Zhang, Yongqing;
    • Becker, Kevin G.;
    • Khraiwesh, Husam;
    • González‐Reyes, José A.;
    • Villalba, José M.;
    • Baur, Joseph A.;
    • Elliott, Peter;
    • Westphal, Christoph;
    • Vlasuk, George P.;
    • Ellis, James L.;
    • Sinclair, David A.
    Publication type:
    Article

  • NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.

    Published in:
    Aging Cell, 2009, v. 8, n. 2, p. 140, doi. 10.1111/j.1474-9726.2009.00461.x
    By:
    • Jiménez-Hidalgo, María;
    • Santos-Ocaña, Carlos;
    • Padilla, Sergio;
    • Villalba, José M.;
    • López-Lluch, Guillermo;
    • Martín-Montalvo, Alejandro;
    • Minor, Robin K.;
    • Sinclair, David A.;
    • de Cabo, Rafael;
    • Navas, Plácido
    Publication type:
    Article

  • Heterogeneity of In Vitro Expanded Mesenchymal Stromal Cells and Strategies to Improve Their Therapeutic Actions.

    Published in:
    Pharmaceutics, 2022, v. 14, n. 5, p. 1112, doi. 10.3390/pharmaceutics14051112
    By:
    • Olmedo-Moreno, Laura;
    • Aguilera, Yolanda;
    • Baliña-Sánchez, Carmen;
    • Martín-Montalvo, Alejandro;
    • Capilla-González, Vivian
    Publication type:
    Article