Found: 3

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  • Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23463-8
    By:
    • Zatreanu, Diana;
    • Robinson, Helen M. R.;
    • Alkhatib, Omar;
    • Boursier, Marie;
    • Finch, Harry;
    • Geo, Lerin;
    • Grande, Diego;
    • Grinkevich, Vera;
    • Heald, Robert A.;
    • Langdon, Sophie;
    • Majithiya, Jayesh;
    • McWhirter, Claire;
    • Martin, Niall M. B.;
    • Moore, Shaun;
    • Neves, Joana;
    • Rajendra, Eeson;
    • Ranzani, Marco;
    • Schaedler, Theresia;
    • Stockley, Martin;
    • Wiggins, Kimberley
    Publication type:
    Article

  • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.

    Published in:
    Nature, 2005, v. 434, n. 7035, p. 917, doi. 10.1038/nature03445
    By:
    • Farmer, Hannah;
    • McCabe, Nuala;
    • Lord, Christopher J.;
    • Tutt, Andrew N. J.;
    • Johnson, Damian A.;
    • Richardson, Tobias B.;
    • Santarosa, Manuela;
    • Dillon, Krystyna J.;
    • Hickson, Ian;
    • Knights, Charlotte;
    • Martin, Niall M. B.;
    • Jackson, Stephen P.;
    • Smith, Graeme C. M.;
    • Ashworth, Alan
    Publication type:
    Article

  • Progress in the Function and Regulation of ADP-Ribosylation.

    Published in:
    Science Signaling, 2011, v. 4, n. 174, p. 1, doi. 10.1126/scisignal.2001645
    By:
    • Hottiger, Michael O.;
    • Boothby, Mark;
    • Koch-Nolte, Friedrich;
    • Lüscher, Bernhard;
    • Martin, Niall M. B.;
    • Plummer, Ruth;
    • Wang, Zhao-Qi;
    • Ziegler, Mathias
    Publication type:
    Article