Works by Marinho, Emmanuel Silva

Results: 67

Ester Production Using the Lipid Composition of Coffee Ground Oil (Coffea arabica): A Theoretical Study of Eversa ® Transform 2.0 Lipase as an Enzymatic Biocatalyst.

Published in:

Compounds, 2023, v. 3, n. 3, p. 411, doi. 10.3390/compounds3030031

By:

Nobre, Millena Mara Rabelo;
Silva, Ananias Freire da;
Menezes, Amanda Maria;
Silva, Francisco Lennon Barbosa da;
Lima, Iesa Matos;
Colares, Regilany Paulo;
Souza, Maria Cristiane Martins de;
Marinho, Emmanuel Silva;
Melo, Rafael Leandro Fernandes;
Santos, José Cleiton Sousa dos;
da Fonseca, Aluísio Marques

Publication type:

Article

Virtual Screening of Citrus Flavonoid Tangeretin: A Promising Pharmacological Tool for the Treatment and Prevention of Zika fever and COVID-19.

Published in:

Journal of Computational Biophysics & Chemistry, 2021, v. 20, n. 3, p. 283, doi. 10.1142/S2737416521500137

By:

Rocha, Matheus Nunes da;
Alves, Daniela Ribeiro;
Marinho, Marcia Machado;
Morais, Selene Maia de;
Marinho, Emmanuel Silva

Publication type:

Article

Virtual Screening of Natural Curcumins and Related Compounds Against SARS-CoV-2.

Published in:

Journal of Computational Biophysics & Chemistry, 2021, v. 20, n. 1, p. 53, doi. 10.1142/S2737416521500046

By:

Alves, Daniela Ribeiro;
da Rocha, Matheus Nunes;
de Sousa, Damião Sampaio;
Oliveira, Iris Cristina Maia;
Marinho, Marcia Machado;
de Morais, Selene Maia;
Marinho, Emmanuel Silva

Publication type:

Article

Antibacterial and Inhibitory Activity of Nora and Mepa Efflux Pumps of Estragole Complexed to β-Cyclodextrin (ES/β-CD) In Vitro Against Staphylococcus aureus Bacteria, Molecular Docking and MPO-Based Pharmacokinetics Prediction.

Published in:

Pharmaceutics, 2024, v. 16, n. 11, p. 1469, doi. 10.3390/pharmaceutics16111469

By:

Costa, Roger Henrique Sousa da;
Pessoa, Renata Torres;
Silva, Eduardo dos Santos;
Araujo, Isaac Moura;
Gonçalves, Sheila Alves;
Rocha, Janaína Esmeraldo;
Pereira Junior, Francisco Nascimento;
Oliveira, Naiara Cipriano;
Oliveira, Victor Moreira de;
Rocha, Matheus Nunes da;
Marinho, Emmanuel Silva;
Kelly Gomes de Carvalho, Natália;
Galberto Martins da Costa, José;
Santos, Hélcio Silva dos;
Menezes, Irwin Rose Alencar de

Publication type:

Article

Evaluation of Emulsification Techniques to Optimize the Properties of Chalcone Nanoemulsions for Antifungal Applications.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 11, p. 1442, doi. 10.3390/ph17111442

By:

Nascimento, Joice Farias do;
Abreu, Flavia Oliveira Monteiro da Silva;
Holanda, Taysse;
Oliveira dos Santos Fontenelle, Raquel;
Prado, Júlio César Sousa;
Marinho, Emmanuel Silva;
da Rocha, Matheus Nunes;
Guedes, Jesyka Macêdo;
Cavalcanti, Bruno Coelho;
Ribeiro, Wesley Lyeverton Correia;
Marinho, Márcia Machado;
Santos, Helcio Silva dos

Publication type:

Article

Investigation of the anti-leishmanial potential of triazole-linked carvacrol–coumarin derivatives: a docking, molecular dynamics, MM/GBSA toxicity approach.

Published in:

Journal of the Iranian Chemical Society, 2025, v. 22, n. 3, p. 459, doi. 10.1007/s13738-024-03166-9

By:

Roberto, Caio Henrique Alexandre;
de Sousa, Damião Sampaio;
da Silva Mendes, Francisco Rogenio;
de Oliveira, Lorena Mayana Beserra;
Teixeira, Alexandre Magno Rodrigues;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking.

Published in:

Biological Chemistry, 2024, v. 405, n. 11/12, p. 727, doi. 10.1515/hsz-2024-0068

By:

Ali, Arif;
de Almeida, Igor Moreira;
Magalhães, Emanuel Paula;
Guedes, Jesyka Macedo;
Cajazeiras, Francisco Ferdinando Mesquita;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
de Menezes, Ramon Róseo Paula Pessoa Bezerra;
Sampaio, Tiago Lima;
Santos, Hélcio Silva dos;
da Silva Júnior, Geraldo Bezerra;
Martins, Alice Maria Costa

Publication type:

Article

Screening of Potential Inhibitors Targeting the Main Protease Structure of SARS-CoV-2 via Molecular Docking, and Approach with Molecular Dynamics, RMSD, RMSF, H-Bond, SASA and MMGBSA.

Published in:

Molecular Biotechnology, 2024, v. 66, n. 8, p. 1919, doi. 10.1007/s12033-023-00831-x

By:

da Fonseca, Aluísio Marques;
Caluaco, Bernardino Joaquim;
Madureira, Junilson Martinho Canjanja;
Cabongo, Sadrack Queque;
Gaieta, Eduardo Menezes;
Djata, Faustino;
Colares, Regilany Paulo;
Neto, Moises Maia;
Fernandes, Carla Freire Celedonio;
Marinho, Gabrielle Silva;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

In Silico Study in MPO and Molecular Docking of the Synthetic Drynaran Analogues Against the Chronic Tinnitus: Modulation of the M1 Muscarinic Acetylcholine Receptor.

Published in:

Molecular Biotechnology, 2024, v. 66, n. 2, p. 254, doi. 10.1007/s12033-023-00748-5

By:

da Rocha, Matheus Nunes;
da Fonseca, Aluísio Marques;
Dantas, Adriana Nogueira Machado;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva;
Marinho, Gabrielle Silva

Publication type:

Article

Synthesis of Quercetin-Metal Complexes, In Vitro and In Silico Anticholinesterase and Antioxidant Evaluation, and In Vivo Toxicological and Anxiolitic Activities.

Published in:

Neurotoxicity Research, 2020, v. 37, n. 4, p. 893, doi. 10.1007/s12640-019-00142-7

By:

da Silva, Wildson Max Barbosa;
de Oliveira Pinheiro, Solange;
Alves, Daniela Ribeiro;
de Menezes, Jane Eire Silva Alencar;
Magalhães, Francisco Ernani Alves;
Silva, Francisca Crislândia Oliveira;
Silva, Jacilene;
Marinho, Emmanuel Silva;
de Morais, Selene Maia

Publication type:

Article

Biocatalysis and in silico study of coconut water peroxidase: A valuable alternative for sustainable and efficient organic synthesis processes.

Published in:

Biocatalysis & Biotransformation, 2025, v. 43, n. 3, p. 280, doi. 10.1080/10242422.2025.2486628

By:

Pinto, Francisco das Chagas Lima;
Bongua, Júnior Inácio;
Paiva, Maria Mabelle Pereira Costa;
de Lemos, Telma Leda Gomes;
Colares, Regilany Paulo;
Marinho, Emmanuel Silva;
Santos, Hélcio Silva dos;
de Oliveira, Mauro Macedo;
da Fonseca, Aluísio Marques

Publication type:

Article

Synthesis of a new quinine dimer biocatalysed by the coconut water.

Published in:

Biocatalysis & Biotransformation, 2022, v. 40, n. 3, p. 209, doi. 10.1080/10242422.2021.1935897

By:

Fonseca, Aluísio M.;
Silva, Leonardo Paes da;
Almeida-Neto, Francisco Wagner de Queiroz;
Colares, Regilany Paulo;
Macedo de Oliveira, Mauro;
Luthierre Gama Cavalcante, Antônio;
Lemos, Telma L. G.;
Braz-Filho, Raimundo;
de Lima-Neto, Pedro;
Marinho, Emmanuel Silva

Publication type:

Article

Antibacterial and Antibiofilm Activities of Hydralazine, an Antihypertensive Drug: In Vitro and In Silico Approaches.

Published in:

Antibiotics (2079-6382), 2025, v. 14, n. 3, p. 286, doi. 10.3390/antibiotics14030286

By:

Pereira, Antônio Mateus Gomes;
da Silva, Benise Ferreira;
Araujo, Ingrid Maria Frota;
Aguiar, Francisco Kauê Carvalho;
Coelho, Paulo Adenes Teixeira;
Costa, Renata Albuquerque;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
Nunes, João Victor Serra;
Carneiro, Victor Alves;
Santos, Hélcio Silva dos

Publication type:

Article

Allosteric modulation of laeviganoid-based clerodane diterpenes derivatives in muscarinic acetylcholine M1 receptor against tinnitus: a structure-based virtual screening approach.

Published in:

Future Journal of Pharmaceutical Sciences, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s43094-025-00783-w

By:

Silva, Jacilene;
da Rocha, Matheus Nunes;
de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
Lúcio, Francisco Nithael Melo;
Marinho, Márcia Machado;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

Structural, Vibrational and Electrochemical Analysis and Antibacterial Potential of Isomeric Chalcones Derived from Natural Acetophenone.

Published in:

Applied Sciences (2076-3417), 2020, v. 10, n. 14, p. 4713, doi. 10.3390/app10144713

By:

Silva, Priscila Teixeira da;
Freitas, Thiago Sampaio de;
Sena, Diniz Maciel;
Bandeira, Paulo Nogueira;
Julião, Murilo Ségio da Silva;
Marinho, Emmanuel Silva;
Alcanfor, Ana Aline Coêlho;
Marinho, Emanuelle Machado;
Lima-Neto, Pedro de;
Nogueira, Carlos Emídio Sampaio;
Coutinho, Henrique Douglas Melo;
Leal, Antonio Linkoln Alves Borges;
Barreto, Humberto Medeiros;
Martins, Natália;
Rodrigues Teixeira, Alexandre Magno;
Santos, Hélcio Silva dos

Publication type:

Article

Robinin Isolated From Solanum Asperum Exhibits Pharmacological Actions in the Central Nervous System of Adult Zebrafish (Danio rerio).

Published in:

Chemistry & Biodiversity, 2025, v. 22, n. 5, p. 1, doi. 10.1002/cbdv.202402173

By:

Lemos, Cecília Guimarães;
Wlisses da Silva, Antonio;
Maciel, Jéssica Bezerra;
Ferreira, Maria Kueirislene Amâncio;
Nunes da Rocha, Matheus;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
Pinto, Francisco das Chagas Lima;
Loiola, Otília Deusdênia;
de Castro Gomes, Andreia Ferreira;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Anxiolytic and Anticonvulsant Potential of Biosynthetic Limonene Derivatives in Adult Zebrafish.

Published in:

Chemistry & Biodiversity, 2025, v. 22, n. 2, p. 1, doi. 10.1002/cbdv.202401663

By:

Cavalcante, Rafaela Mesquita Bastos;
Ferreira, Maria Kueirislene Amâncio;
Wlisses da Silva, Antonio;
Mendes, Francisco Rogenio da Silva;
Guimarães Lemos, Cecília;
Bezerra Maciel, Jéssica;
Rocha Cavalcante, Thaís;
Silva Marinho, Emmanuel;
Alencar de Menezes, Jane Eire Silva;
dos Santos, Helcio Silva

Publication type:

Article

Anxiolytic and Anticonvulsant Effects of Fisetin Isolated from Bauhinia pentandra on Adult Zebrafish (Danio rerio).

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 11, p. 1, doi. 10.1002/cbdv.202401207

By:

da Silva, Horlando Carlota;
das Chagas Lima Pinto, Francisco;
Silva Marinho, Emmanuel;
Alencar de Menezes, Jane Eire Silva;
Kueirislene Amâncio Ferreira, Maria;
da Silva, Antonio Wlisses;
Machado Marinho, Emanuelle;
Marinho, Márcia Machado;
Pessoa Bezerra de Menezes, Ramon Róseo Paula;
Washington Cavalcante, John;
Silva dos Santos, Hélcio;
Pessoa, Otília Deusdênia Loiola;
Santiago, Gilvandete Maria Pinheiro

Publication type:

Article

Withanicandrin Isolated from Datura Ferox Promotes Antinociception by Modulating the Asics and TRPS Channels and Anti‐Inflammation in Adult Zebrafish.

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 7, p. 1, doi. 10.1002/cbdv.202400538

By:

Maciel, Jéssica Bezerra;
Liberato, Hortência Ribeiro;
da Silva, Antônio Wlisses;
da Silva, João Pedro Vieira;
das Chagas L. Pinto, Francisco;
de Lima Rebouças, Emanuela;
da Silva, Francisco Sydney Henrique;
Ferreira, Maria Kueirislene Amâncio;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
Pessoa, Otília Deusdênia Loiola;
de Barros Silva, Paulo Goberlânio;
Coelho‐de‐Souza, Andrelina Noronha;
Guedes, Maria Izabel Florindo;
de Castro Gomes, Andreia Ferreira;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Essential Oils from the Genus Piper Promote Antinociception by Modulating TRP Channels and Anti‐Inflammatory Effects in Adult Zebrafish.

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 3, p. 1, doi. 10.1002/cbdv.202301807

By:

Pereira, Wandresa Francelino;
Everson da Silva, Luiz;
do Amaral, Wanderlei;
Andrade Rebelo, Ricardo;
Quefi, Blasco;
Wlisses da Silva, Antonio;
Silva Marinho, Emmanuel;
Borges Leal, Antonio Linkoln Alves;
Mesquita Cajazeiras, Francisco Ferdinando;
Amâncio Ferreira, Maria Kueirislene;
Bezerra Maciel, Jéssica;
Ribeiro Liberato, Hortência;
Guedes, Jesyka Macêdo;
Silva Alencar de Menezes, Jane Eire;
Teixeira, Alexandre Magno Rodrigues;
Silva dos Santosa, Helcio

Publication type:

Article

Assessment In vitro and In silico of the Activity of Thiadiazines as NorA Efflux Pump Inhibitors.

Published in:

Current Microbiology, 2024, v. 81, n. 10, p. 1, doi. 10.1007/s00284-024-03836-0

By:

de Araújo, Ana Carolina Justino;
Freitas, Priscilla Ramos;
Araújo, Isaac Moura;
de Oliveira Borges, João Arthur;
Gonçalves, Sheila Alves;
Paulo, Cícera Laura Roque;
Almeida, Ray Silva;
de Moraes Oliveira-Tintino, Cícera Datiane;
de Araújo-Neto, José Bezerra;
dos Santos Nascimento, Igor José;
de Araújo-Júnior, João Xavier;
da Silva-Júnior, Edeildo Ferreira;
de Aquino, Thiago Mendonça;
Junior, Francisco Jaime Bezerra Mendonça;
Marinho, Emmanuel Silva;
dos Santos, Helcio Silva;
de Alencar Menezes, Irwin Rose;
Tintino, Saulo Relison;
Coutinho, Henrique Douglas Melo;
Braga, Maria Flaviana Bezerra Morais

Publication type:

Article

Antimicrobial, Antibiofilm Activities and Synergic Effect of Triterpene 3β,6β,16β-trihydroxyilup-20(29)-ene Isolated from Combretum leprosum Leaves Against Staphylococcus Strains.

Published in:

Current Microbiology, 2023, v. 80, n. 5, p. 1, doi. 10.1007/s00284-023-03284-2

By:

Teixeira, Edson Holanda;
Andrade, Alexandre Lopes;
Pereira, Rafael;
Farias, Livia Pontes;
Monteiro, Gabrieli Sobral;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
Santos, Hélcio Silva;
de Vasconcelos, Mayron Alves

Publication type:

Article

Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg.

Published in:

Current Microbiology, 2021, v. 78, n. 5, p. 1926, doi. 10.1007/s00284-021-02449-1

By:

do Vale, Jean Parcelli Costa;
Vasconcelos, Mayron Alves;
Arruda, Francisco Vassiliepe Sousa;
Firmino, Nairley Cardoso Sá;
Pereira, Anna Luísa;
Andrade, Alexandre Lopes;
Saker-Sampaio, Silvana;
Sampaio, Alexandre Holanda;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
Marinho, Márcia Machado;
Rodrigues, Tigressa Helena Soares;
Teixeira, Edson Holanda;
dos Santos, Hélcio Silva

Publication type:

Article

Chemical Composition, Antibacterial and Inhibitory Activity of the Efflux Pump of Essential Oils from Croton piauhiensis Müll.

Published in:

Nutraceuticals (1661-3821), 2023, v. 3, n. 4, p. 591, doi. 10.3390/nutraceuticals3040042

By:

Cruz, Beatriz Gonçalves;
de Freitas, Thiago Sampaio;
Costa, Maria do Socorro;
da Silva, Ana Raquel Pereira;
Coutinho, Henrique Douglas Melo;
de Morais, Selene Maia;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
Silva dos Santos, Hélcio

Publication type:

Article

Antioxidant Activity and Anxiolytic Effect of Cnidoscolus quercifolius Pohl Stem Bark Extract in Zebrafish.

Published in:

Future Pharmacology, 2025, v. 5, n. 2, p. 16, doi. 10.3390/futurepharmacol5020016

By:

do Nascimento, Joice Barbosa;
da Silva Mendes, Johnatan Wellisson;
Viturino, José Jonas Ferreira;
Inácio da Silva, Maria;
Pereira da Silva, Mariana;
Duarte Leite, Débora Odília;
Marinho, Emmanuel Silva;
de Menezes, Jane Eire Silva Alencar;
Santos, Hélcio Silva dos;
da Costa, José Galberto Martins

Publication type:

Article

Polyphenols of four medicinal plant extracts and relation with antifungal activities through in vitro and in silico studies.

Published in:

Revista Ciência e Natura, 2024, v. 46, p. 1, doi. 10.5902/2179460X76669

By:

da Silva Lopes, Francisco Flávio;
Soares Frota, Lucas;
Maria Neves, Andréa;
Oliveira Lima, Cecília Lara;
Ferreira da Silva, Marcus Vinícius;
Nunes da Rocha, Matheus;
Machado Marinho, Marcia;
dos Santos Fontenellem, Raquel Oliveira;
Silva Marinho, Emmanuel;
Maia Morais, Selene

Publication type:

Article

Synthesis, antibiotic modifying activity, ADMET study and molecular docking of chalcone (E)-3-(2,4-dichlorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying MepA efflux pumps.

Published in:

Archives of Microbiology, 2022, v. 204, n. 1, p. 1, doi. 10.1007/s00203-021-02666-z

By:

Rocha, Janaína Esmeraldo;
de Freitas, Thiago Sampaio;
da Cunha Xavier, Jayze;
Pereira, Raimundo Luiz Silva;
Pereira, Francisco Nascimento Jr;
Nogueira, Carlos Emídio Sampaio;
Marinho, Márcia Machado;
Bandeira, Paulo Nogueira;
Fernandes, Maria Alyce Albuquerque;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
dos Santos, Hélcio Silva;
Coutinho, Henrique Douglas Melo

Publication type:

Article

Chemical composition and potentiating action of Norfloxacin mediated by the essential oil of Piper caldense C.D.C. against Staphylococcus aureus strains overexpressing efflux pump genes.

Published in:

Archives of Microbiology, 2021, v. 203, n. 7, p. 4727, doi. 10.1007/s00203-021-02393-5

By:

Leal, Antonio Linkoln Alves Borges;
Bezerra, Camila Fonseca;
Confortin, Camila;
da Silva, Luiz Everson;
Marinho, Emanuelle Machado;
Marinho, Márcia Machado;
Vasconcelos, Mayron Alves;
da Silva, Terezinha Gonçalves;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
Coutinho, Henrique Douglas Melo;
Barreto, Humberto Medeiros;
dos Santos, Hélcio Silva

Publication type:

Article

Anacardic Acid Complexes as Possible Agents Against Alzheimer's Disease Through Their Antioxidant, In vitro, and In silico Anticholinesterase and Ansiolic Actions.

Published in:

Neurotoxicity Research, 2021, v. 39, n. 2, p. 467, doi. 10.1007/s12640-020-00306-w

By:

da Silva, Wildson Max Barbosa;
Pinheiro, Solange de Oliveira;
Alves, Daniela Ribeiro;
de Menezes, Jane Eire Silva Alencar;
Magalhães, Francisco Ernani Alves;
Silva, Francisca Crislândia Oliveira;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
de Morais, Selene Maia

Publication type:

Article

Insights of potential trypanocidal effect of the synthetic derivative (2E)-1-(4-aminophenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one: in vitro assay, MEV analysis, quantum study, molecular docking, molecular dynamics, MPO analysis, and predictive ADMET.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 10, p. 7797, doi. 10.1007/s00210-024-03138-z

By:

Marinho, Márcia Machado;
da Rocha, Matheus Nunes;
Magalhães, Emanuel Paula;
Ribeiro, Lyanna Rodrigues;
Roberto, Caio Henrique Alexandre;
de Queiroz Almeida-Neto, Francisco Wagner;
Monteiro, Marília Lopes;
Nunes, João Victor Serra;
de Menezes, Ramon Róseo Paula Pessoa Bezerra;
Marinho, Emmanuel Silva;
de Lima Neto, Pedro;
Martins, Alice Maria Costa;
dos Santos, Hélcio Silva

Publication type:

Article

Anxiolytic-like effect of natural product 2-hydroxy-3,4,6-trimethoxyacetophenone isolated from Croton anisodontus in adult zebrafish via serotonergic neuromodulation involvement of the 5-HT system.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2021, v. 394, n. 10, p. 2023, doi. 10.1007/s00210-021-02116-z

By:

da Silva, Antonio Wlisses;
Ferreira, Maria Kueirislene A.;
Rebouças, Emanuela L.;
Mendes, Francisco Rogenio S.;
dos S. Moura, Atilano Lucas;
de Menezes, Jane Eire S. A.;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
Santos, Hélcio S.;
Teixeira, Alexandre M. R.

Publication type:

Article

Synthesis, molecular docking, ADMET, and evaluation of the anxiolytic effect in adult zebrafish of synthetic chalcone (E)‐3‐(4‐(dimethylamino)phenyl)‐1‐(2‐hydroxyphenyl)prop‐2‐en‐1‐one: An in vivo and in silico approach

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 2, p. 290, doi. 10.1111/fcp.12960

By:

Santos Oliveira, Larissa;
Kueirislene Amâncio Ferreira, Maria;
Wagner de Queiroz Almeida‐Neto, Francisco;
Wlisses da Silva, Antonio;
Ivo Lima Pinto Filho, José;
Nunes da Rocha, Matheus;
Machado Marinho, Emanuelle;
Henrique Ferreira Ribeiro, Walber;
Machado Marinho, Márcia;
Silva Marinho, Emmanuel;
Eire Silva Alencar de Menezes, Jane;
dos Santos, Hélcio Silva

Publication type:

Article

Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains.

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 1, p. 84, doi. 10.1111/fcp.12950

By:

de Araújo, Ana Carolina Justino;
Freitas, Priscilla Ramos;
Araújo, Isaac Moura;
Siqueira, Gustavo Miguel;
de Oliveira Borges, João Arthur;
Alves, Daniel Sampaio;
Miranda, Gustavo Marinho;
dos Santos Nascimento, Igor José;
de Araújo‐Júnior, João Xavier;
da Silva‐Júnior, Edeildo Ferreira;
de Aquino, Thiago Mendonça;
Junior, Francisco Jaime Bezerra Mendonça;
Marinho, Emmanuel Silva;
dos Santos, Helcio Silva;
Tintino, Saulo Relison;
Coutinho, Henrique Douglas Melo

Publication type:

Article

Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one.

Published in:

Fundamental & Clinical Pharmacology, 2022, v. 36, n. 6, p. 1066, doi. 10.1111/fcp.12785

By:

Hemília de Souza Nunes, Paula;
Sampaio de Freitas, Thiago;
Esmeraldo Rocha, Janaína;
Luiz Silva Pereira, Raimundo;
Machado Marinho, Marcia;
de Oliveira, Mateus Rodrigues;
Santos Oliveira, Larissa;
Machado Marinho, Emanuelle;
Silva Marinho, Emmanuel;
Sousa Aquino, Silvia;
Emidio Sampaio Nogueira, Carlos;
Douglas Melo Coutinho, Henrique;
Nogueira Bandeira, Paulo;
Magno Rodrigues Teixeira, Alexandre;
dos Santos, Hélcio Silva

Publication type:

Article

Hypoglycemic effect on adult zebrafish (Danio rerio) of the 3β‐6β‐16β‐trihydroxylup‐20(29)‐ene triterpene isolated from Combretum leprosum leaves in vivo and in silico approach.

Published in:

Fundamental & Clinical Pharmacology, 2022, v. 36, n. 5, p. 818, doi. 10.1111/fcp.12776

By:

Coutinho, Marnielle Rodrigues;
da Silva, Antonio Wlisses;
Ferreira, Maria Kueirislene Amâncio;
de Lima Rebouças, Emanuela;
Mendes, Francisco Rogênio S.;
Teixeira, Edson Holanda;
Marinho, Emanuelle Machado;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Effects of ketamine in methicillin-resistant Staphylococcus aureus and in silico interaction with sortase A.

Published in:

Canadian Journal of Microbiology, 2021, v. 67, n. 12, p. 885, doi. 10.1139/cjm-2021-0093

By:

Coutinho, Tatiana do Nascimento Paiva;
Barroso, Fátima Daiana Dias;
da Silva, Cecília Rocha;
da Silva, Anderson Ramos;
Cabral, Vitória Pessoa de Farias;
Sá, Lívia Gurgel do Amaral Valente;
Cândido, Thiago Mesquita;
da Silva, Lisandra Juvencio;
Ferreira, Thais Lima;
da Silva, Wildson Max Barbosa;
Silva, Jacilene;
Marinho, Emmanuel Silva;
Cavalcanti, Bruno Coelho;
Moraes, Manoel Odorico de;
Nobre Júnior, Hélio Vitoriano;
Andrade Neto, João Batista

Publication type:

Article

Structure and Ligand Based Virtual Screening and MPO Topological Analysis of Triazolo Thiadiazepine-fused Coumarin Derivatives as Anti-Parkinson Drug Candidates.

Published in:

Molecular Biotechnology, 2025, v. 67, n. 6, p. 2339, doi. 10.1007/s12033-024-01200-y

By:

Pereira, Antônio Mateus Gomes;
de Oliveira, Victor Moreira;
da Rocha, Matheus Nunes;
Roberto, Caio Henrique Alexandre;
Cajazeiras, Francisco Ferdinando Mesquita;
Guedes, Jesyka Macêdo;
Marinho, Márcia Machado;
Teixeira, Alexandre Magno Rodrigues;
Marinho, Emmanuel Silva;
de Lima-Neto, Pedro;
dos Santos, Hélcio Silva

Publication type:

Article

Ligand and structure-based virtual screening approaches in drug discovery: minireview.

Published in:

Molecular Diversity, 2025, v. 29, n. 3, p. 2799, doi. 10.1007/s11030-024-10979-6

By:

da Rocha, Matheus Nunes;
de Sousa, Damião Sampaio;
da Silva Mendes, Francisco Rogenio;
dos Santos, Helcio Silva;
Marinho, Gabrielle Silva;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva

Publication type:

Article

In Vitro and In Silico Study of the Inhibitory Potential of Riparins I, II, III, and IV on the NorA Efflux Pump of Staphylococcus aureus.

Published in:

ChemistrySelect, 2025, v. 10, n. 23, p. 1, doi. 10.1002/slct.202500292

By:

Rodrigues dos Santos Barbosa, Cristina;
Rocha, Janaína Esmeraldo;
Silveira, Zildene de Sousa;
de Araújo, Ana Carolina Justino;
Freitas, Priscilla Ramos;
Oliveira‐Tintino, Cícera Datiane de Morais;
Macêdo, Nair Silva;
de Freitas, Thiago Sampaio;
da Cunha, Francisco Assis Bezerra;
Marinho, Emmanuel Silva;
de Sousa, Gabriela Ribeiro;
Barbosa‐Filho, José Maria;
de Souza‐Ferrari, Jailton;
Silva dos Santos, Hélcio;
Coutinho, Henrique Douglas Melo

Publication type:

Article

Antitrypanosomal Potential of Chalcone‐Based Ursolic Acid Derivatives via Ligand‐Based Virtual Screening, DMPK Analyses, Molecular Dynamics Simulation, and MM/GBSA Binding Energy.

Published in:

ChemistrySelect, 2024, v. 9, n. 44, p. 1, doi. 10.1002/slct.202402673

By:

Nunes, João Victor Serra;
da Rocha, Matheus Nunes;
de de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva;
Marinho, Márcia Machado;
Martins, Alice Maria Costa

Publication type:

Article

Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporter.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1425485

By:

Belal, Amany;
Elballal, Mohammed S.;
Al-Karmalawy, Ahmed A.;
Hassan, Ahmed H. E.;
Roh, Eun Joo;
Ghoneim, Mohammed M.;
Ali, Mohamed A. M.;
Obaidullah, Ahmad J.;
Alotaibi, Jawaher M.;
Shaaban, Salwa;
Elanany, Mohamed A.;
Marinho, Emmanuel Silva;
Dimiić, Dusan

Publication type:

Article

Structure-based virtual screening of mangiferin derivatives with antidiabetic action: a molecular docking and dynamics study and MPO-based drug-likeness approach.

Published in:

3 Biotech, 2024, v. 14, n. 5, p. 1, doi. 10.1007/s13205-024-03978-9

By:

da Silva Lopes, Francisco Flávio;
Lúcio, Francisco Nithael Melo;
da Rocha, Matheus Nunes;
de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
de Morais, Selene Maia

Publication type:

Article

De novo design of bioactive phenol and chromone derivatives for inhibitors of Spike glycoprotein of SARS-CoV-2 in silico.

Published in:

3 Biotech, 2023, v. 13, n. 9, p. 1, doi. 10.1007/s13205-023-03695-9

By:

Lima, Joan Petrus Oliveira;
da Fonseca, Aluísio Marques;
Marinho, Gabrielle Silva;
da Rocha, Matheus Nunes;
Marinho, Emanuelle Machado;
dos Santos, Helcio Silva;
Freire, Rafael Melo;
Marinho, Emmanuel Silva;
de Lima-Neto, Pedro;
Fechine, Pierre Basílio Almeida

Publication type:

Article

Heterocyclic chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(thiophen-2-yl) prop-2-en-1-one derived from a natural product with antinociceptive, anti-inflammatory, and hypoglycemic effect in adult zebrafish.

Published in:

3 Biotech, 2023, v. 13, n. 8, p. 1, doi. 10.1007/s13205-023-03696-8

By:

Ferreira, Maria Kueirislene Amancio;
Freitas, Wendy Pascoal Oliveira;
Barbosa, Italo Moura;
da Rocha, Matheus Nunes;
da Silva, Antônio Wlisses;
de Lima Rebouças, Emanuela;
da Silva Mendes, Francisco Rogênio;
Alves, Carlucio Roberto;
Nunes, Paulo Iury Gomes;
Marinho, Márcia Machado;
Furtado, Roselayne Ferro;
Santos, Flávia Almeida;
Marinho, Emmanuel Silva;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Helcio Silva

Publication type:

Article

Synthesis, structural, characterization, antibacterial and antibiotic modifying activity, ADMET study, molecular docking and dynamics of chalcone (E)-1-(4-aminophenyl)-3-(4-nitrophenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 4, p. 1670, doi. 10.1080/07391102.2023.2213777

By:

Souza, Mikael Amaro de;
Rodrigues, Leilane Gomes;
Rocha, Janaina Esmeraldo;
de Freitas, Thiago Sampaio;
Bandeira, Paulo Nogueira;
Marinho, Márcia Machado;
Nunes da Rocha, Matheus;
Marinho, Emmanuel Silva;
Honorato Barreto, Antonio Cesar;
Coutinho, Henrique Douglas Melo;
Silva, Lorena Mara Alexandre;
Julião, Murilo Sergio da Silva;
Marques Canuto, Kirley;
Marques da Fonseca, Aluísio;
Teixeira, Alexandre Magno Rodrigues;
dos Santos, Hélcio Silva

Publication type:

Article

Synthesis and anxiolytic effect of europium metallic complex containing lapachol [Eu(DBM)<sub>3</sub>. LAP] in adult zebrafish through serotonergic neurotransmission: in vivo and in silico approach.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 3, p. 1280, doi. 10.1080/07391102.2023.2199087

By:

de Menezes, Jorge Fernando Silva;
Sá Pires Silva, Andrei Marcelino;
Aparecida Faria de Almeida, Edna;
da Silva, Ananias Freire;
Morais Bomfim De Lima, Julia;
da Silva, Antonio Wlisses;
Ferreira, Maria Kueirislene Amâncio;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva;
Marinho, Gabrielle Silva;
Marques da Fonseca, Aluísio

Publication type:

Article

Isolation, characterization and in silico study of propenamide alkaloids from Hymenoepmecis bicolor poison against active μ-opioid receptor.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 24, p. 14621, doi. 10.1080/07391102.2023.2183043

By:

Marques da Fonseca, Aluísio;
Freire da Silva, Ananias;
Barbosa da Silva, Francisco Lennon;
Caluaco, Bernardino Joaquim;
Gaieta, Eduardo Menezes;
Nunes da Rocha, Matheus;
Colares, Regilany Paulo;
Sobczak, Jober Fernando;
Marinho, Gabrielle Silva;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

Anxiolytic and anticonvulsant effect of Ibuprofen derivative through GABAergic neuromodulation in adult Zebrafish.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 12055, doi. 10.1080/07391102.2023.2170915

By:

Rodrigues Garcia, Tatiana;
Freire, Paulo de Tarso Cavalcante;
da Silva, Antonio Wlisses;
Ferreira, Maria Kueirislene Amâncio;
Rebouças, Emanuela de Lima;
Mendes, Francisco Rogênio Silva;
Marinho, Emanuelle Machado;
Marinho, Marcia Machado;
Teixeira, Alexandre Magno Rodrigues;
Marinho, Emmanuel Silva;
Bandeira, Paulo Nogueira;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Helcio Silva

Publication type:

Article

GABA<sub>A</sub> and serotonergic receptors participation in anxiolytic effect of chalcones in adult zebrafish.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 12426, doi. 10.1080/07391102.2023.2167116

By:

Mendes, Francisco Rogênio Silva;
da Silva, Antonio Wlisses;
Ferreira, Maria Kueirislene Amâncio;
Rebouças, Emanuela de Lima;
Moura Barbosa, Italo;
da Rocha, Matheus Nunes;
Henrique Ferreira Ribeiro, Walber;
Menezes, Ramon Róseo Paula Pessoa Bezerra de;
Magalhães, Emanuel Paula;
Marinho, Emanuelle Machado;
Marinho, Márcia Machado;
Bandeira, Paulo Nogueira;
de Menezes, Jane Eire Silva Alencar;
Marinho, Emmanuel Silva;
dos Santos, Hélcio Silva

Publication type:

Article

Naphthoquinones biflorin and bis-biflorin (Capraria biflora) as possible inhibitors of the fungus Candida auris polymerase: molecular docking, molecular dynamics, MM/GBSA calculations and in silico drug-likeness study.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 11564, doi. 10.1080/07391102.2022.2163702

By:

da Fonseca, Aluísio Marques;
Soares, Neidelenio Baltazar;
Colares, Regilany Paulo;
Macedo de Oliveira, Mauro;
Santos Oliveira, Larissa;
Marinho, Gabrielle Silva;
Raya Paula de Lima, Mira;
da Rocha, Matheus Nunes;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article