Works by Marialessandra Contino

Results: 47

Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control.

Published in:

Drugs & Therapy Studies, 2013, v. 3, n. 1, p. 20, doi. 10.4081/dts.2013.e5

By:

Perrone, Maria Grazia;
Contino, Marialessandra;
Scilimati, Antonio

Publication type:

Article

Guinea-pig ileum as ex vivo model useful to characterize ligands displaying Imidazoline I2 and Adrenergic alpha2 mixed activity: a preliminary study.

Published in:

Drugs & Therapy Studies, 2013, v. 3, n. 1, p. 1, doi. 10.4081/dts.2013.e1

By:

Contino, Marialessandra;
Carrieri, Antonio;
Berardi, Francesco;
Leopoldo, Marcello;
Perrone, Roberto;
Thomas, Russell;
Colabufo, Nicola Antonio

Publication type:

Article

Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 1033, doi. 10.3390/cells9041033

By:

Kopecka, Joanna;
Godel, Martina;
Dei, Silvia;
Giampietro, Roberta;
Belisario, Dimas Carolina;
Akman, Muhlis;
Contino, Marialessandra;
Teodori, Elisabetta;
Riganti, Chiara

Publication type:

Article

Editorial: Molecular modulators of GPCRs signal transduction.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1252734

By:

Vrecl, Milka;
Contino, Marialessandra;
Leopoldo, Marcello

Publication type:

Article

Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 1, p. 135, doi. 10.3390/ph17010135

By:

Miciaccia, Morena;
Rizzo, Francesca;
Centonze, Antonella;
Cavallaro, Gianfranco;
Contino, Marialessandra;
Armenise, Domenico;
Baldelli, Olga Maria;
Solidoro, Roberta;
Ferorelli, Savina;
Scarcia, Pasquale;
Agrimi, Gennaro;
Zingales, Veronica;
Cimetta, Elisa;
Ronsisvalle, Simone;
Sipala, Federica Maria;
Polosa, Paola Loguercio;
Fortuna, Cosimo Gianluca;
Perrone, Maria Grazia;
Scilimati, Antonio

Publication type:

Article

Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells.

Published in:

Pharmaceuticals (14248247), 2019, v. 12, n. 2, p. 98, doi. 10.3390/ph12020098

By:

de Matos, Ana M.;
Martins, Alice;
Man, Teresa;
Evans, David;
Walter, Magnus;
Oliveira, Maria Conceição;
López, Óscar;
Fernandez-Bolaños, José G.;
Dätwyler, Philipp;
Ernst, Beat;
Macedo, M. Paula;
Contino, Marialessandra;
Colabufo, Nicola A.;
Rauter, Amélia P.

Publication type:

Article

An updated patent review on P-glycoprotein inhibitors (2011-2018).

Published in:

Expert Opinion on Therapeutic Patents, 2019, v. 29, n. 6, p. 455, doi. 10.1080/13543776.2019.1618273

By:

Leopoldo, Marcello;
Nardulli, Patrizia;
Contino, Marialessandra;
Leonetti, Francesco;
Luurtsema, Gert;
Colabufo, Nicola Antonio

Publication type:

Article

6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 974, doi. 10.1080/14756366.2020.1747449

By:

Braconi, Laura;
Bartolucci, Gianluca;
Contino, Marialessandra;
Chiaramonte, Niccolò;
Giampietro, Roberta;
Manetti, Dina;
Perrone, Maria Grazia;
Romanelli, Maria Novella;
Colabufo, Nicola Antonio;
Riganti, Chiara;
Dei, Silvia;
Teodori, Elisabetta

Publication type:

Article

Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine.

Published in:

Pharmacology Research & Perspectives, 2015, v. 3, n. 5, p. 1, doi. 10.1002/prp2.160

By:

Gualdani, Roberta;
Tadini ‐ Buoninsegni, Francesco;
Roselli, Mariagrazia;
Defrenza, Ivana;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Lentini, Giovanni

Publication type:

Article

Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6581, doi. 10.3390/ijms24076581

By:

Graziano, Giovanni;
Stefanachi, Angela;
Contino, Marialessandra;
Prieto-Díaz, Rubén;
Ligresti, Alessia;
Kumar, Poulami;
Scilimati, Antonio;
Sotelo, Eddy;
Leonetti, Francesco

Publication type:

Article

Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6381, doi. 10.3390/ijms24076381

By:

Thejer, Bashar M.;
Infantino, Vittoria;
Santarsiero, Anna;
Pappalardo, Ilaria;
Abatematteo, Francesca S.;
Teakel, Sarah;
Van Oosterum, Ashleigh;
Mach, Robert H.;
Denora, Nunzio;
Lee, Byung Chul;
Resta, Nicoletta;
Bagnulo, Rosanna;
Niso, Mauro;
Contino, Marialessandra;
Montsch, Bianca;
Heffeter, Petra;
Abate, Carmen;
Cahill, Michael A.

Publication type:

Article

Multi-Target Directed Ligands (MTDLs) Binding the σ 1 Receptor as Promising Therapeutics: State of the Art and Perspectives.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6359, doi. 10.3390/ijms22126359

By:

Abatematteo, Francesca Serena;
Niso, Mauro;
Contino, Marialessandra;
Leopoldo, Marcello;
Abate, Carmen

Publication type:

Article

Overexpression of Human ABCB1 and ABCG2 Reduces the Susceptibility of Cancer Cells to the Histone Deacetylase 6-Specific Inhibitor Citarinostat.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2592, doi. 10.3390/ijms22052592

By:

Wu, Chung-Pu;
Hung, Cheng-Yu;
Lusvarghi, Sabrina;
Chang, Yen-Fu;
Hsiao, Sung-Han;
Huang, Yang-Hui;
Hung, Tai-Ho;
Yu, Jau-Song;
Ambudkar, Suresh. V.;
Contino, Marialessandra;
Heo, Yong-Seok

Publication type:

Article

Therapeutic Agents for Oxaliplatin-Induced Peripheral Neuropathy; Experimental and Clinical Evidence.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1393, doi. 10.3390/ijms22031393

By:

Kawashiri, Takehiro;
Mine, Keisuke;
Kobayashi, Daisuke;
Inoue, Mizuki;
Ushio, Soichiro;
Uchida, Mayako;
Egashira, Nobuaki;
Shimazoe, Takao;
Contino, Marialessandra

Publication type:

Article

MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 9, p. 3333, doi. 10.3390/ijms21093333

By:

Riganti, Chiara;
Giampietro, Roberta;
Kopecka, Joanna;
Costamagna, Costanzo;
Abatematteo, Francesca Serena;
Contino, Marialessandra;
Abate, Carmen

Publication type:

Article

New Strategies to Overcome Resistance to Chemotherapy and Immune System in Cancer.

Published in:

2019

By:

Riganti, Chiara;
Contino, Marialessandra

Publication type:

Editorial

Antiproliferative and cytotoxic effects of some σ2 agonists and σ1 antagonists in tumour cell lines.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 370, n. 2, p. 106

By:

Colabufo, Nicola Antonio;
Berardi, Francesco;
Contino, Marialessandra;
Niso, Mauro;
Abate, Carmen;
Perrone, Roberto;
Tortorella, Vincenzo

Publication type:

Article

A new method for evaluating σ2 ligand activity in the isolated guinea-pig bladder.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 368, n. 2, p. 106, doi. 10.1007/s00210-003-0777-5

By:

Colabufo, Nicola A.;
Berardi, Francesco;
Contino, Marialessandra;
Perrone, Roberto;
Tortorella, Vincenzo

Publication type:

Article

PB28, the Sigma-1 and Sigma-2 Receptors Modulator With Potent Anti–SARS-CoV-2 Activity: A Review About Its Pharmacological Properties and Structure Affinity Relationships.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.589810

By:

Abate, Carmen;
Niso, Mauro;
Abatematteo, Francesca Serena;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

Editorial: The Canonical and Non-Canonical Endocannabinoid System as a Target in Cancer and Acute and Chronic Pain.

Published in:

2020

By:

Contino, Marialessandra;
McCormick, Peter J.

Publication type:

Editorial

The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line.

Published in:

Molecular Cancer, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1476-4598-12-47

By:

Pagliarulo, Vincenzo;
Ancona, Patrizia;
Niso, Mauro;
Colabufo, Nicola Antonio;
Contino, Marialessandra;
Cormio, Luigi;
Azzariti, Amalia;
Pagliarulo, Arcangelo

Publication type:

Article

Editorial: The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation.

Published in:

2017

By:

Contino, Marialessandra;
Capparelli, Elena;
Colabufo, Nicola A.;
Bush, Ashley I.

Publication type:

Editorial

The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxelmediated resistance in gastric cancer cell lines.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1129832

By:

Schirizzi, Annalisa;
Contino, Marialessandra;
Carrieri, Livianna;
Riganti, Chiara;
De Leonardis, Giampiero;
Scavo, Maria Principia;
Perrone, Maria Grazia;
Miciaccia, Morena;
Kopecka, Joanna;
Refolo, Maria Grazia;
Lotesoriere, Claudio;
Depalo, Nicoletta;
Rizzi, Federica;
Giannelli, Gianluigi;
Messa, Caterina;
D'Alessandro, Rosalba

Publication type:

Article

Assessing the Optimal Deoxygenation Pattern of Dodecyl Glycosides for Antimicrobial Activity Against Bacillus anthracis.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 12, p. 2224, doi. 10.1002/ejoc.201801764

By:

Dias, Catarina;
Martins, Alice;
Pelerito, Ana;
Oliveira, Maria C.;
Contino, Marialessandra;
Colabufo, Nicola A.;
Rauter, Amélia P.

Publication type:

Article

Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers.

Published in:

ChemMedChem, 2017, v. 12, n. 16, p. 1369, doi. 10.1002/cmdc.201700239

By:

Teodori, Elisabetta;
Dei, Silvia;
Bartolucci, Gianluca;
Perrone, Maria Grazia;
Manetti, Dina;
Romanelli, Maria Novella;
Contino, Marialessandra;
Colabufo, Nicola Antonio

Publication type:

Article

Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs).

Published in:

ChemMedChem, 2016, v. 11, n. 11, p. 1172, doi. 10.1002/cmdc.201500439

By:

Perrone, Maria Grazia;
Vitale, Paola;
Panella, Andrea;
Ferorelli, Savina;
Contino, Marialessandra;
Lavecchia, Antonio;
Scilimati, Antonio

Publication type:

Article

A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression.

Published in:

ChemMedChem, 2016, v. 11, n. 4, p. 374, doi. 10.1002/cmdc.201500538

By:

Guglielmo, Stefano;
Contino, Marialessandra;
Lazzarato, Loretta;
Perrone, Maria Grazia;
Blangetti, Marco;
Fruttero, Roberta;
Colabufo, Nicola Antonio

Publication type:

Article

Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules.

Published in:

ChemMedChem, 2016, v. 11, n. 1, p. 93, doi. 10.1002/cmdc.201500417

By:

Carocci, Alessia;
Catalano, Alessia;
Turi, Francesco;
Lovece, Angelo;
Cavalluzzi, Maria M.;
Bruno, Claudio;
Colabufo, Nicola A.;
Contino, Marialessandra;
Perrone, Maria G.;
Franchini, Carlo;
Lentini, Giovanni

Publication type:

Article

Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity.

Published in:

ChemMedChem, 2015, v. 10, n. 8, p. 1339, doi. 10.1002/cmdc.201500143

By:

Teodori, Elisabetta;
Dei, Silvia;
Floriddia, Elisa;
Perrone, Maria Grazia;
Manetti, Dina;
Romanelli, Maria Novella;
Contino, Marialessandra;
Colabufo, Nicola Antonio

Publication type:

Article

PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD.

Published in:

ChemMedChem, 2014, v. 9, n. 1, p. 38, doi. 10.1002/cmdc.201300362

By:

Leopoldo, Marcello;
Contino, Marialessandra;
Berardi, Francesco;
Perrone, Roberto;
Colabufo, Nicola Antonio

Publication type:

Article

Inside Cover: Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity (ChemMedChem 12/2013).

Published in:

ChemMedChem, 2013, v. 8, n. 12, p. 1898, doi. 10.1002/cmdc.201390051

By:

Niso, Mauro;
Abate, Carmen;
Contino, Marialessandra;
Ferorelli, Savina;
Azzariti, Amalia;
Perrone, Roberto;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity.

Published in:

ChemMedChem, 2013, v. 8, n. 12, p. 2026, doi. 10.1002/cmdc.201300291

By:

Niso, Mauro;
Abate, Carmen;
Contino, Marialessandra;
Ferorelli, Savina;
Azzariti, Amalia;
Perrone, Roberto;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease.

Published in:

ChemMedChem, 2012, v. 7, n. 3, p. 391, doi. 10.1002/cmdc.201100469

By:

Contino, Marialessandra;
Cantore, Mariangela;
Capparelli, Elena;
Perrone, Maria Grazia;
Niso, Mauro;
Inglese, Carmela;
Berardi, Francesco;
Leopoldo, Marcello;
Perrone, Roberto;
Colabufo, Nicola Antonio

Publication type:

Article

Inside Cover: 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ8-Δ7 Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity (ChemMedChem 1/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 1, p. 2, doi. 10.1002/cmdc.201090062

By:

Abate, Carmen;
Niso, Mauro;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Ferorelli, Savina;
Perrone, Roberto;
Berardi, Francesco

Publication type:

Article

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ8-Δ7 Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity.

Published in:

ChemMedChem, 2011, v. 6, n. 1, p. 73, doi. 10.1002/cmdc.201000371

By:

Abate, Carmen;
Niso, Mauro;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Ferorelli, Savina;
Perrone, Roberto;
Berardi, Francesco

Publication type:

Article

Multi-Drug-Resistance-Reverting Agents: 2-Aryloxazole and 2-Arylthiazole Derivatives as Potent BCRP or MRP1 Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 2, p. 188, doi. 10.1002/cmdc.200800329

By:

Colabufo, Nicola A.;
Berardi, Francesco;
Perrone, Maria Grazia;
Cantore, Mariangela;
Contino, Marialessandra;
Inglese, Carmela;
Niso, Mauro;
Perrone, Roberto

Publication type:

Article

Small and innovative molecules as new strategy to revert MDR.

Published in:

Frontiers in Oncology, 2014, v. 3, p. 1, doi. 10.3389/fonc.2014.00002

By:

Zinzi, Laura;
Capparelli, Elena;
Cantore, Mariangela;
Contino, Marialessandra;
Leopoldo, Marcello;
Colabufo, Nicola Antonio

Publication type:

Article

Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06488-4

By:

Dias, Catarina;
Pais, João P.;
Nunes, Rafael;
Blázquez-Sánchez, Maria-Teresa;
Marquês, Joaquim T.;
Almeida, Andreia F.;
Serra, Patrícia;
Xavier, Nuno M.;
Vila-Viçosa, Diogo;
Machuqueiro, Miguel;
Viana, Ana S.;
Martins, Alice;
Santos, Maria S.;
Pelerito, Ana;
Dias, Ricardo;
Tenreiro, Rogério;
Oliveira, Maria C.;
Contino, Marialessandra;
Colabufo, Nicola A.;
de Almeida, Rodrigo F. M.

Publication type:

Article

Editorial: Macromolecular interactions in signaling pathways: from classical approaches to virtual reality.

Published in:

Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1388849

By:

Leopoldo, Marcello;
Contino, Marialessandra;
Maudsley, Stuart;
Vrecl, Milka

Publication type:

Article

Functionalized Coumarine Fragment to Obtain Fluorescent and Selective P-Glycoprotein Ligands.

Published in:

Archiv der Pharmazie, 2016, v. 349, n. 3, p. 161, doi. 10.1002/ardp.201500325

By:

Capparelli, Elena;
Contino, Marialessandra;
Perrone, Maria G.;
Berardi, Francesco;
Perrone, Roberto;
Leopoldo, Marcello;
Colabufo, Nicola A.

Publication type:

Article

miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives.

Published in:

Molecules, 2014, v. 19, n. 5, p. 5611, doi. 10.3390/molecules19055611

By:

Gisel, Andreas;
Valvano, Mirna;
El Idrissi, Imane Ghafir;
Nardulli, Patrizia;
Azzariti, Amalia;
Carrieri, Antonio;
Contino, Marialessandra;
Colabufo, Nicola Antonio

Publication type:

Article

Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.

Published in:

Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 11, p. 1453

By:

Nicola Antonio Colabufo;
Francesco Berardi;
Marialessandra Contino;
Ferruccio Fazio;
Mario Matarrese;
Rosa Maria Moresco;
Mauro Niso;
Roberto Perrone;
Vincenzo Tortorella

Publication type:

Article

Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 2, p. 247

By:

Marcello Leopoldo;
Francesco Berardi;
Nicola A. Colabufo;
Marialessandra Contino;
Enza Lacivita;
Roberto Perrone;
Vincenzo Tortorella

Publication type:

Article

ABC transporters in CSCs membranes as a novel target for treating tumor relapse.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00163

By:

Zinzi, Laura;
Contino, Marialessandra;
Cantore, Mariangela;
Capparelli, Elena;
Leopoldo, Marcello;
Colabufo, Nicola A.

Publication type:

Article

ABC transporters in CSCs membranes as a novel target for treating tumour relapse.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00163

By:

ZINZI, LAURA;
Contino, Marialessandra;
Cantore, Mariangela;
Capparelli, Elena;
Leopoldo, Marcello;
Colabufo, Nicola Antonio

Publication type:

Article

Overcoming Multidrug Resistance (MDR): Design, Biological Evaluation and Molecular Modelling Studies of 2,4‐Substituted Quinazoline Derivatives.

Published in:

ChemMedChem, 2022, v. 17, n. 12, p. 1, doi. 10.1002/cmdc.202200027

By:

Braconi, Laura;
Teodori, Elisabetta;
Contino, Marialessandra;
Riganti, Chiara;
Bartolucci, Gianluca;
Manetti, Dina;
Romanelli, Maria Novella;
Perrone, Maria Grazia;
Colabufo, Nicola Antonio;
Guglielmo, Stefano;
Dei, Silvia

Publication type:

Article

Dual Inhibitors of P-gp and Carbonic Anhydrase XII (hCA XII) against Tumor Multidrug Resistance with Piperazine Scaffold †.

Published in:

Molecules, 2024, v. 29, n. 14, p. 3290, doi. 10.3390/molecules29143290

By:

Braconi, Laura;
Riganti, Chiara;
Parenti, Astrid;
Cecchi, Marta;
Nocentini, Alessio;
Bartolucci, Gianluca;
Menicatti, Marta;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Manetti, Dina;
Romanelli, Maria Novella;
Supuran, Claudiu T.;
Teodori, Elisabetta

Publication type:

Article