Found: 50
Select item for more details and to access through your institution.
QSAR and Chemical Read-Across Analysis of 370 Potential MGMT Inactivators to Identify the Structural Features Influencing Inactivation Potency.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 8, p. 2170, doi. 10.3390/pharmaceutics15082170
- By:
- Publication type:
- Article
Alkylpurine--DNA--N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 1, p. 253, doi. 10.1172/JCI59334
- By:
- Publication type:
- Article
Development and Application of a Slot-Blot Assay Using the Damage Sensing Protein Atl1 to Detect and Quantify O 6 -Alkylated Guanine Bases in DNA.
- Published in:
- Toxics, 2024, v. 12, n. 9, p. 649, doi. 10.3390/toxics12090649
- By:
- Publication type:
- Article
Experimental Study. ETHANOL MODULATES RAT HEPATIC DNA REPAIR FUNCTIONS.
- Published in:
- Alcohol & Alcoholism, 2001, v. 36, n. 5, p. 369, doi. 10.1093/alcalc/36.5.369
- By:
- Publication type:
- Article
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 10, p. 5524, doi. 10.1093/nar/gkt198
- By:
- Publication type:
- Article
The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 5, p. 3047, doi. 10.1093/nar/gks1476
- By:
- Publication type:
- Article
Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 16, p. 7806, doi. 10.1093/nar/gks522
- By:
- Publication type:
- Article
Expression of O<sup>6</sup>-Alkylguanine-DNA Alkyltransferase in Normal andMalignant Bladder Tissue of Egyptian Patients.
- Published in:
- Journal of Nucleic Acids, 2010, p. 1, doi. 10.4061/2010/840230
- By:
- Publication type:
- Article
Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells.
- Published in:
- Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-154
- By:
- Publication type:
- Article
Increased N7-methyldeoxyguanosine DNA adducts after occupational exposure to pesticides and influence of genetic polymorphisms of paraoxonase-1 and glutathione S-transferase M1 and T1.
- Published in:
- Environmental & Molecular Mutagenesis, 2015, v. 56, n. 5, p. 437, doi. 10.1002/em.21929
- By:
- Publication type:
- Article
Flipping of alkylated DNA damage bridges base and nucleotide excision repair.
- Published in:
- Nature, 2009, v. 459, n. 7248, p. 808, doi. 10.1038/nature08076
- By:
- Publication type:
- Article
hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents.
- Published in:
- Oncogene, 1997, v. 15, n. 1, p. 45, doi. 10.1038/sj.onc.1201167
- By:
- Publication type:
- Article
Reduced MGMT activity in human colorectal adenomas is associated with K-ras GC→AT transition mutations in a population exposed to methylating agents.
- Published in:
- Carcinogenesis, 2004, v. 25, n. 7, p. 1243, doi. 10.1093/carcin/bgh111
- By:
- Publication type:
- Article
Associations between tissue-specific DNA alkylation, DNA repair and cell proliferation in the colon and colon tumour yield in mice treated with 1,2-dimethylhydrazine.
- Published in:
- Carcinogenesis, 2003, v. 24, n. 3, p. 527, doi. 10.1093/carcin/24.3.527
- By:
- Publication type:
- Article
In vivo administration of O6-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine.
- Published in:
- Carcinogenesis, 2000, v. 21, n. 4, p. 593, doi. 10.1093/carcin/21.4.593
- By:
- Publication type:
- Article
Contribution of ogt-encoded alkyltransferase to resistance to chloroethylnitrosoureas in nucleotide excision repair-deficient Escherichia coli.
- Published in:
- Carcinogenesis, 1996, v. 17, n. 8, p. 1609, doi. 10.1093/carcin/17.8.1609
- By:
- Publication type:
- Article
A novel DNA damage recognition protein in Schizosaccharomyces pombe.
- Published in:
- Nucleic Acids Research, 2006, v. 34, n. 8, p. 2347, doi. 10.1093/nar/gkl270
- By:
- Publication type:
- Article
Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT).
- Published in:
- Nucleic Acids Research, 2006, v. 34, n. 6, p. 1884, doi. 10.1093/nar/gkl117
- By:
- Publication type:
- Article
Inhibition of O<sup>6</sup>-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli.
- Published in:
- Nucleic Acids Research, 2005, v. 33, n. 12, p. 3837, doi. 10.1093/nar/gki696
- By:
- Publication type:
- Article
Identification and characterisation of the Drosophila melanogaster O[sup 6]-alkylguanine-DNA alkyltransferase cDNA.
- Published in:
- Nucleic Acids Research, 1999, v. 27, n. 8, p. 1795, doi. 10.1093/nar/27.8.1795
- By:
- Publication type:
- Article
O[sup6]-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy.
- Published in:
- BioEssays, 2002, v. 24, n. 3, p. 255, doi. 10.1002/bies.10063
- By:
- Publication type:
- Article
Effect of stable integration of the Escherichia coli ada gene on the sensitivity of Saccharomyces cerevisiae to the toxic and mutagenic effects of alkylating agents.
- Published in:
- Environmental & Molecular Mutagenesis, 2000, v. 35, n. 1, p. 66, doi. 10.1002/(SICI)1098-2280(2000)35:1<66::AID-EM9>3.0.CO;2-2
- By:
- Publication type:
- Article
Targeting human 8-oxoguanine DNA glycosylase (hOGG1) to mitochondria enhances cisplatin cytotoxicity in hepatoma cells.
- Published in:
- Carcinogenesis, 2007, v. 28, n. 8, p. 1629, doi. 10.1093/carcin/bgm072
- By:
- Publication type:
- Article
Quantitative trait locus analysis reveals two intragenic sites that influence <it>O</it><sup>6</sup>-alkylguanine-DNA alkyltransferase activity in peripheral blood mononuclear cells.
- Published in:
- Carcinogenesis, 2005, v. 26, n. 8, p. 1473, doi. 10.1093/carcin/bgi087
- By:
- Publication type:
- Article
Association between lung cancer risk and single nucleotide polymorphisms in the first intron and codon 178 of the DNA repair gene, O.
- Published in:
- International Journal of Cancer, 2008, v. 122, n. 4, p. 791, doi. 10.1002/ijc.23059
- By:
- Publication type:
- Article
Smoking is associated with a decrease of O.
- Published in:
- International Journal of Cancer, 2006, v. 119, n. 2, p. 463, doi. 10.1002/ijc.21790
- By:
- Publication type:
- Article
Pharmacokinetic, biochemical and clinical effects of dimethyltriazenoimidazole-4-carboxamide-bischloroethylnitrosourea combination therapy in patients with advanced breast cancer.
- Published in:
- International Journal of Cancer, 2003, v. 103, n. 5, p. 686, doi. 10.1002/ijc.10849
- By:
- Publication type:
- Article
A potential role of heat shock proteins and nicotinamide N-methyl transferase in predicting response to radiation in bladder cancer.
- Published in:
- International Journal of Cancer, 2002, v. 101, n. 5, p. 454, doi. 10.1002/ijc.10631
- By:
- Publication type:
- Article
Effect of O.
- Published in:
- International Journal of Cancer, 2002, v. 100, n. 5, p. 615, doi. 10.1002/ijc.10532
- By:
- Publication type:
- Article
O
- Published in:
- International Journal of Cancer, 2000, v. 88, n. 3, p. 469, doi. 10.1002/1097-0215(20001101)88:3<469::AID-IJC21>3.0.CO;2-7
- By:
- Publication type:
- Article
O
- Published in:
- International Journal of Cancer, 2000, v. 85, n. 2, p. 248, doi. 10.1002/(SICI)1097-0215(20000115)85:2<248::AID-IJC16>3.0.CO;2-V
- By:
- Publication type:
- Article
ogt alkyltransferase enhances dibromoalkane mutagenicity in excision repair-deficient escherichia coli K-12.
- Published in:
- Molecular Carcinogenesis, 1995, v. 12, n. 2, p. 110, doi. 10.1002/mc.2940120208
- By:
- Publication type:
- Article
bcl-2 delay of alkylating agent-induced apoptotic death in a murine hemopoietic stem cell line.
- Published in:
- Molecular Carcinogenesis, 1994, v. 11, n. 1, p. 49, doi. 10.1002/mc.2940110109
- By:
- Publication type:
- Article
Tissue-specific expression and induction of human O<sup>6</sup>-alkylguanine-dna alkyltransferase in transgenic mice.
- Published in:
- Molecular Carcinogenesis, 1992, v. 6, n. 1, p. 26, doi. 10.1002/mc.2940060106
- By:
- Publication type:
- Article
Isolation and partial characterization of murine O<sup>6</sup>-alkyiguanine-DNA-alkyltransferase: Comparative sequence and structural properties.
- Published in:
- Molecular Carcinogenesis, 1992, v. 5, n. 2, p. 161, doi. 10.1002/mc.2940050212
- By:
- Publication type:
- Article
Four-hourly scheduling of temozolomide improves tumour growth delay but not therapeutic index in A375M melanoma xenografts.
- Published in:
- 2000
- By:
- Publication type:
- journal article
Mechanisms of carcinogenicity/chemotherapy by O6-methylguanine.
- Published in:
- Mutagenesis, 2002, v. 17, n. 6, p. 483, doi. 10.1093/mutage/17.6.483
- By:
- Publication type:
- Article
O6-Methylguanine-DNA methyltransferase inactivation and chemotherapy.
- Published in:
- British Medical Bulletin, 2008, v. 85, n. 1, p. 17, doi. 10.1093/bmb/ldm036
- By:
- Publication type:
- Article
Targeting O<sup>6</sup>-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy.
- Published in:
- Cellular & Molecular Life Sciences, 2010, v. 67, n. 21, p. 3663, doi. 10.1007/s00018-010-0491-7
- By:
- Publication type:
- Article
Induction of O<sup>6</sup>-Alkylguanine-DNA-Alkyltransferase in the Hepatocytes of Rats Following Treatment with 2-Acetylaminofluorene.
- Published in:
- DNA & Cell Biology, 1997, v. 16, n. 4, p. 493, doi. 10.1089/dna.1997.16.493
- By:
- Publication type:
- Article
Dual agent chemoprotection by retroviral co-expression of either MDR1 or MRP1 with the P<sub>140</sub>K mutant of O<sup>6</sup>-methylguanine-DNA-methyl transferase.
- Published in:
- Journal of Gene Medicine, 2006, v. 8, n. 8, p. 972, doi. 10.1002/jgm.914
- By:
- Publication type:
- Article
The P140K mutant of human O<sup>6</sup>-methylguanine-DNA-methyltransferase (MGMT) confers resistance in vitro and in vivo to temozolomide in combination with the novel MGMT inactivator O<sup>6</sup>-(4-bromothenyl)guanine.
- Published in:
- Journal of Gene Medicine, 2006, v. 8, n. 1, p. 29, doi. 10.1002/jgm.816
- By:
- Publication type:
- Article
Equal Potency of Gammaretroviral and Lentiviral SIN Vectors for Expression of O<sup>6</sup>-Methylguanine–DNA Methyltransferase in Hematopoietic cells.
- Published in:
- Molecular Therapy, 2006, v. 13, n. 2, p. 391, doi. 10.1016/j.ymthe.2005.08.012
- By:
- Publication type:
- Article
Erratum to “Enhanced in Vivo Selection of Bone Marrow Cells by Retroviral-Mediated Coexpression of Mutant O <sup>6</sup>-Methylguanine-DNA-methyltransferase and HOXB4”
- Published in:
- 2005
- By:
- Publication type:
- Correction Notice
Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O<sup>6</sup>-methylguanine-DNA-methyltransferase and HOXB4
- Published in:
- Molecular Therapy, 2004, v. 10, n. 5, p. 862, doi. 10.1016/j.ymthe.2004.07.019
- By:
- Publication type:
- Article
Heterogeneity of O[sup 6] -Alkylguanine-DNA Alkyltransferase Activity in Colorectal Cancer: Implications for Treatment.
- Published in:
- Oncology, 2002, v. 63, n. 4, p. 393, doi. 10.1159/000066221
- By:
- Publication type:
- Article
Thresholds for Genotoxic Carcinogens.
- Published in:
- Toxicologic Pathology, 2000, v. 28, n. 3, p. 375, doi. 10.1177/019262330002800304
- By:
- Publication type:
- Article
Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI.
- Published in:
- Virology Journal, 2006, v. 3, p. 14, doi. 10.1186/1743-422X-3-14
- By:
- Publication type:
- Article
The DNA Alkyltransferase Family of DNA Repair Proteins: Common Mechanisms, Diverse Functions.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 463, doi. 10.3390/ijms25010463
- By:
- Publication type:
- Article
Cytostatic drug resistance: parallel assessment of glutathione-based detoxifying enzymes, O.
- Published in:
- British Journal of Haematology, 1993, v. 85, n. 1, p. 103, doi. 10.1111/j.1365-2141.1993.tb08652.x
- By:
- Publication type:
- Article