Works by Maretzky, Thorsten

Results: 28

ADAM10 cleavage of N-cadherin and regulation of cell–cell adhesion andβ-catenin nuclear signalling.

Published in:

2005

By:

Reiss, Karina;
Maretzky, Thorsten;
Ludwig, Andreas;
Tousseyn, Thomas;
de Strooper, Bart;
Hartmann, Dieter;
Saftig, Paul

Publication type:

Correction Notice

ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion andß-catenin nuclear signalling.

Published in:

EMBO Journal, 2005, v. 24, n. 4, p. 742, doi. 10.1038/sj.emboj.7600548

By:

Reiss, Karina;
Maretzky, Thorsten;
Ludwig, Andreas;
Tousseyn, Thomas;
de Strooper, Bart;
Hartmann, Dieter;
Saftig, Paul

Publication type:

Article

The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 3, p. 2247, doi. 10.1002/jcp.26097

By:

Urriola‐Muñoz, Paulina;
Li, Xue;
Maretzky, Thorsten;
McIlwain, David R.;
Mak, Tak W.;
Reyes, Juan G.;
Blobel, Carl P.;
Moreno, Ricardo D.

Publication type:

Article

DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation.

Published in:

EMBO Reports, 2023, v. 24, n. 5, p. 1, doi. 10.15252/embr.202255543

By:

Teghanemt, Athmane;
Misel‐Wuchter, Kara;
Heath, Jace;
Thurman, Andrew;
Pulipati, Priyanjali;
Dixit, Garima;
Geesala, Ramasatya;
Meyerholz, David K;
Maretzky, Thorsten;
Pezzulo, Alejandro;
Issuree, Priya D

Publication type:

Article

Characterization of the catalytic properties of the membrane-anchored metalloproteinase ADAM9 in cell-based assays.

Published in:

Biochemical Journal, 2017, v. 474, n. 9, p. 1467, doi. 10.1042/BCJ20170075

By:

Maretzky, Thorsten;
Swendeman, Steven;
Mogollon, Elin;
Weskamp, Gisela;
Sahin, Umut;
Reiss, Karina;
Blobel, Carl P.

Publication type:

Article

The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner.

Published in:

Frontiers in Cellular & Infection Microbiology, 2021, p. N.PAG, doi. 10.3389/fcimb.2020.620392

By:

Skurski, Joseph;
Dixit, Garima;
Blobel, Carl P.;
Issuree, Priya D.;
Maretzky, Thorsten

Publication type:

Article

A Disintegrin and Metalloproteases (ADAMs): Activation, Regulation and Mechanisms of Catalysis.

Published in:

2021

By:

Maretzky, Thorsten

Publication type:

Editorial

ADAM10 Site-Dependent Biology: Keeping Control of a Pervasive Protease.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4969, doi. 10.3390/ijms22094969

By:

Tosetti, Francesca;
Alessio, Massimo;
Poggi, Alessandro;
Zocchi, Maria Raffaella;
Maretzky, Thorsten;
Baykov, Alexande

Publication type:

Article

Role of ADAM10 and ADAM17 in Regulating CD137 Function.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2730, doi. 10.3390/ijms22052730

By:

Seidel, Jana;
Leitzke, Sinje;
Ahrens, Björn;
Sperrhacke, Maria;
Bhakdi, Sucharit;
Reiss, Karina;
Maretzky, Thorsten

Publication type:

Article

Constitutive and Regulated Shedding of Soluble FGF Receptors Releases Biologically Active Inhibitors of FGF-2.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2712, doi. 10.3390/ijms22052712

By:

Hanneken, Anne;
Mercado, Maluz;
Maher, Pamela;
Maretzky, Thorsten

Publication type:

Article

ADAM10 Plasma and CSF Levels Are Increased in Mild Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2416, doi. 10.3390/ijms22052416

By:

Pereira Vatanabe, Izabela;
Peron, Rafaela;
Mantellatto Grigoli, Marina;
Pelucchi, Silvia;
De Cesare, Giulia;
Magalhães, Thamires;
Manzine, Patricia Regina;
Figueredo Balthazar, Marcio Luiz;
Di Luca, Monica;
Marcello, Elena;
Cominetti, Marcia Regina;
Maretzky, Thorsten

Publication type:

Article

Quantitative Proteomics Reveals Changes Induced by TIMP-3 on Cell Membrane Composition and Novel Metalloprotease Substrates.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2392, doi. 10.3390/ijms22052392

By:

Carreca, Anna Paola;
Pravatà, Veronica Maria;
D'Apolito, Danilo;
Bonelli, Simone;
Calligaris, Matteo;
Monaca, Elisa;
Müller, Stephan A.;
Lichtenthaler, Stefan F.;
Scilabra, Simone Dario;
Maretzky, Thorsten

Publication type:

Article

Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1846, doi. 10.3390/ijms22041846

By:

Alabi, Rolake O.;
Lora, Jose;
Celen, Arda B.;
Maretzky, Thorsten;
Blobel, Carl P.;
Kambe, Taiho

Publication type:

Article

Phosphatidylserine exposure is required for ADAM17 sheddase function.

Published in:

Nature Communications, 2016, v. 7, n. 5, p. 11523, doi. 10.1038/ncomms11523

By:

Sommer, Anselm;
Kordowski, Felix;
Büch, Joscha;
Maretzky, Thorsten;
Evers, Astrid;
Andrä, Jörg;
Düsterhöft, Stefan;
Michalek, Matthias;
Lorenzen, Inken;
Somasundaram, Prasath;
Tholey, Andreas;
Sönnichsen, Frank D.;
Kunzelmann, Karl;
Heinbockel, Lena;
Nehls, Christian;
Gutsmann, Thomas;
Grötzinger, Joachim;
Bhakdi, Sucharit;
Reiss, Karina

Publication type:

Article

Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.

Published in:

Science Signaling, 2015, v. 8, n. 401, p. 1, doi. 10.1126/scisignal.aac5356

By:

Maney, Sathish K.;
McIlwain, David R.;
Polz, Robin;
Pandyra, Aleksandra A.;
Sundaram, Balamurugan;
Wolff, Dorit;
Ohishi, Kazuhito;
Maretzky, Thorsten;
Brooke, Matthew A.;
Evers, Astrid;
Vasudevan, Ananda A. Jaguva;
Aghaeepour, Nima;
Scheller, Jürgen;
Münk, Carsten;
Häussinger, Dieter;
Mak, Tak W.;
Nolan, Garry P.;
Kelsell, David P.;
Blobel, Carl P.;
Lang, Karl S.

Publication type:

Article

Advantages of Tyrosine Kinase Anti-Angiogenic Cediranib over Bevacizumab: Cell Cycle Abrogation and Synergy with Chemotherapy.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 7, p. 682, doi. 10.3390/ph14070682

By:

Bi, Jianling;
Dixit, Garima;
Zhang, Yuping;
Devor, Eric J.;
Losh, Haley A.;
Newtson, Andreea M.;
Coleman, Kristen L.;
Santillan, Donna A.;
Maretzky, Thorsten;
Thiel, Kristina W.;
Leslie, Kimberly K.

Publication type:

Article

LRRK2 G2019S Promotes Colon Cancer Potentially via LRRK2–GSDMD Axis-Mediated Gut Inflammation.

Published in:

Cells (2073-4409), 2024, v. 13, n. 7, p. 565, doi. 10.3390/cells13070565

By:

Wang, Yuhang;
Gao, Joyce Z.;
Sakaguchi, Taylor;
Maretzky, Thorsten;
Gurung, Prajwal;
Narayanan, Nandakumar S.;
Short, Sarah;
Xiong, Yiqin;
Kang, Zizhen

Publication type:

Article

Functional Distinctions of Endometrial Cancer-Associated Mutations in the Fibroblast Growth Factor Receptor 2 Gene.

Published in:

Cells (2073-4409), 2023, v. 12, n. 18, p. 2227, doi. 10.3390/cells12182227

By:

Dixit, Garima;
Pappas, Benjamin A.;
Bhardwaj, Gourav;
Schanz, Willow;
Maretzky, Thorsten

Publication type:

Article

ADAM10-Mediated E-Cadherin Release Is Regulated by Proinflammatory Cytokines and Modulates Keratinocyte Cohesion in Eczematous Dermatitis.

Published in:

Journal of Investigative Dermatology, 2008, v. 128, n. 7, p. 1737, doi. 10.1038/sj.jid.5701242

By:

Maretzky, Thorsten;
Scholz, Felix;
Köten, Bente;
Proksch, Ehrhardt;
Saftig, Paul;
Reiss, Karina

Publication type:

Article

ADAM17 Controls Endochondral Ossiffication by Regulating Terminal Differentiation of Chondrocytes.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 15, p. 3077, doi. 10.1128/MCB.00291-13

By:

Hall, Katherine C.;
Hill, Daniel;
Otero, Miguel;
Plumb, Darren A.;
Froemel, Dara;
Dragomir, Cecilia L.;
Maretzky, Thorsten;
Boskey, Adele;
Crawford, Howard C.;
Selleri, Licia;
Goldring, Mary B.;
Blobel, Carl P.

Publication type:

Article

L1 Is Sequentially Processed by Two Differently Activated Metalloproteases and Presenilin/&#x03B3-Secretase and Regulates Neural Cell Adhesion, Cell Migration, and Neurite Outgrowth.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 20, p. 9040, doi. 10.1128/MCB.25.20.9040-9053.2005

By:

Maretzky, Thorsten;
Schulte, Marc;
Ludwig, Andreas;
Rose-John, Stefan;
Blobel, Carl;
Hartmann, Dieter;
Altevogt, Peter;
Saftig, Paul;
Reiss, Karma

Publication type:

Article

FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways.

Published in:

Clinical & Translational Medicine, 2023, v. 13, n. 5, p. 1, doi. 10.1002/ctm2.1223

By:

Dixit, Garima;
Gonzalez‐Bosquet, Jesus;
Skurski, Joseph;
Devor, Eric J.;
Dickerson, Erin B.;
Nothnick, Warren B.;
Issuree, Priya D.;
Leslie, Kimberly K.;
Maretzky, Thorsten

Publication type:

Article

iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.

Published in:

European Journal of Immunology, 2016, v. 46, n. 12, p. 2737, doi. 10.1002/eji.201646482

By:

Qing, Xiaoping;
D. Rogers, Lindsay;
Mortha, Arthur;
Lavin, Yonit;
Redecha, Patricia;
Issuree, Priya D.;
Maretzky, Thorsten;
Merad, Miriam;
R. McIlwain, David;
Mak, Tak W.;
Overall, Christopher M.;
Blobel, Carl P.;
Salmon, Jane E.

Publication type:

Article

CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28914-4

By:

Teghanemt, Athmane;
Pulipati, Priyanjali;
Misel-Wuchter, Kara;
Day, Kenneth;
Yorek, Matthew S.;
Yi, Ren;
Keen, Henry L.;
Au, Christy;
Maretzky, Thorsten;
Gurung, Prajwal;
Littman, Dan R.;
Issuree, Priya D.

Publication type:

Article

Novel functions of inactive rhomboid proteins in immunity and disease.

Published in:

Journal of Leukocyte Biology, 2019, v. 106, n. 4, p. 823, doi. 10.1002/JLB.3VMR0219-069R

By:

Geesala, Ramasatyaveni;
Issuree, Priya D.;
Maretzky, Thorsten

Publication type:

Article

Loss of RHBDF2 results in an early‐onset spontaneous murine colitis.

Published in:

Journal of Leukocyte Biology, 2019, v. 105, n. 4, p. 767, doi. 10.1002/JLB.4A0718-283RR

By:

Geesala, Ramasatyaveni;
Schanz, Willow;
Biggs, Mikayla;
Dixit, Garima;
Skurski, Joseph;
Gurung, Prajwal;
Meyerholz, David K.;
Elliott, David;
Issuree, Priya D.;
Maretzky, Thorsten

Publication type:

Article

Substrate‐selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.

Published in:

FASEB Journal, 2020, v. 34, n. 4, p. 4956, doi. 10.1096/fj.201902649R

By:

Tang, Beiyu;
Li, Xue;
Maretzky, Thorsten;
Perez‐Aguilar, Jose Manuel;
McIlwain, David;
Xie, Yifang;
Zheng, Yufang;
Mak, Tak W.;
Weinstein, Harel;
Blobel, Carl P.

Publication type:

Article

iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 928, doi. 10.1172/JCI66168

By:

Issuree, Priya Darshinee A.;
Maretzky, Thorsten;
McIlwain, David R.;
Monette, Sébastien;
Qing, Xiaoping;
Lang, Philipp A.;
Swendeman, Steven L.;
Park-Min, Kyung-Hyun;
Binder, Nikolaus;
Kalliolias, George D.;
Yarilina, Anna;
Horiuchi, Keisuke;
Ivashkiv, Lionel B.;
Mak, Tak W.;
Salmon, Jane E.;
Blobel, Carl P.

Publication type:

Article