Works by Marcus Bantscheff

Results: 41
    1

    One‐Step Synthesis of Photoaffinity Probes for Live‐Cell MS‐Based Proteomics.

    Published in:
    Chemistry - A European Journal, 2021, v. 27, n. 71, p. 17880, doi. 10.1002/chem.202102036
    By:
    • Fallon, David J.;
    • Lehmann, Stephanie;
    • Chung, Chun‐wa;
    • Phillipou, Alex;
    • Eberl, Christian;
    • Fantom, Ken G. M.;
    • Zappacosta, Francesca;
    • Patel, Vipulkumar K.;
    • Bantscheff, Marcus;
    • Schofield, Christopher J.;
    • Tomkinson, Nicholas C. O.;
    • Bush, Jacob T.
    Publication type:
    Article
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    The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.

    Published in:
    Science Translational Medicine, 2022, v. 14, n. 667, p. 1, doi. 10.1126/scitranslmed.abo7219
    By:
    • Arendse, Lauren B.;
    • Murithi, James M.;
    • Qahash, Tarrick;
    • Pasaje, Charisse Flerida A.;
    • Godoy, Luiz C.;
    • Dey, Sumanta;
    • Gibhard, Liezl;
    • Ghidelli-Disse, Sonja;
    • Drewes, Gerard;
    • Bantscheff, Marcus;
    • Lafuente-Monasterio, Maria J.;
    • Fienberg, Stephen;
    • Wambua, Lynn;
    • Gachuhi, Samuel;
    • Coertzen, Dina;
    • van der Watt, Mariëtte;
    • Reader, Janette;
    • Aswat, Ayesha S.;
    • Erlank, Erica;
    • Venter, Nelius
    Publication type:
    Article
    8

    CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model.

    Published in:
    Science Translational Medicine, 2020, v. 12, n. 541, p. 1, doi. 10.1126/scitranslmed.aaz2415
    By:
    • Ketley, Ami;
    • Wojciechowska, Marzena;
    • Ghidelli-Disse, Sonja;
    • Bamborough, Paul;
    • Ghosh, Tushar K.;
    • Morato, Marta Lopez;
    • Sedehizadeh, Saam;
    • Malik, Naveed Altaf;
    • Tang, Zhenzhi;
    • Powalowska, Paulina;
    • Tanner, Matthew;
    • Billeter-Clark, Rudolf;
    • Trueman, Rebecca C.;
    • Geiszler, Philippine C.;
    • Agostini, Alessandra;
    • Othman, Othman;
    • Bösche, Markus;
    • Bantscheff, Marcus;
    • Rüdiger, Martin;
    • Mossakowska, Danuta E.
    Publication type:
    Article
    9

    Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs.

    Published in:
    Angewandte Chemie International Edition, 2021, v. 60, n. 43, p. 23327, doi. 10.1002/anie.202109237
    By:
    • Law, Robert P.;
    • Nunes, Joao;
    • Chung, Chun‐wa;
    • Bantscheff, Marcus;
    • Buda, Karol;
    • Dai, Han;
    • Evans, John P.;
    • Flinders, Adam;
    • Klimaszewska, Diana;
    • Lewis, Antonia J.;
    • Muelbaier, Marcel;
    • Scott‐Stevens, Paul;
    • Stacey, Peter;
    • Tame, Christopher J.;
    • Watt, Gillian F.;
    • Zinn, Nico;
    • Queisser, Markus A.;
    • Harling, John D.;
    • Benowitz, Andrew B.
    Publication type:
    Article
    10

    Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition.

    Published in:
    Molecular Systems Biology, 2024, v. 20, n. 4, p. 458, doi. 10.1038/s44320-024-00025-w
    By:
    • Burtscher, Mira L;
    • Gade, Stephan;
    • Garrido-Rodriguez, Martin;
    • Rutkowska, Anna;
    • Werner, Thilo;
    • Eberl, H Christian;
    • Petretich, Massimo;
    • Knopf, Natascha;
    • Zirngibl, Katharina;
    • Grandi, Paola;
    • Bergamini, Giovanna;
    • Bantscheff, Marcus;
    • Fälth-Savitski, Maria;
    • Saez-Rodriguez, Julio
    Publication type:
    Article
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    Systematic analysis of protein turnover in primary cells.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03106-1
    By:
    • Mathieson, Toby;
    • Franken, Holger;
    • Kosinski, Jan;
    • Kurzawa, Nils;
    • Zinn, Nico;
    • Sweetman, Gavain;
    • Poeckel, Daniel;
    • Ratnu, Vikram S.;
    • Schramm, Maike;
    • Becher, Isabelle;
    • Steidel, Michael;
    • Kyung-Min Noh;
    • Bergamini, Giovanna;
    • Beck, Martin;
    • Bantscheff, Marcus;
    • Savitski, Mikhail M.
    Publication type:
    Article
    13

    Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

    Published in:
    Nature Biotechnology, 2011, v. 29, n. 3, p. 255, doi. 10.1038/nbt.1759
    By:
    • Bantscheff, Marcus;
    • Hopf, Carsten;
    • Savitski, Mikhail M.;
    • Dittmann, Antje;
    • Grandi, Paola;
    • Michon, Anne-Marie;
    • Schlegl, Judith;
    • Abraham, Yann;
    • Becher, Isabelle;
    • Bergamini, Giovanna;
    • Boesche, Markus;
    • Delling, Manja;
    • Eberhard, Dirk;
    • Huthmacher, Carola;
    • Mathieson, Toby;
    • Poeckel, Daniel;
    • Reader, Valérie;
    • Strunk, Katja;
    • Sweetman, Gavain;
    • Kruse, Ulrich
    Publication type:
    Article
    14

    Human Proteinpedia enables sharing of human protein data.

    Published in:
    2008
    By:
    • Mathivanan, Suresh;
    • Ahmed, Mukhtar;
    • Ahn, Natalie G.;
    • Alexandre, Hainard;
    • Amanchy, Ramars;
    • Andrews, Philip C.;
    • Bader, Joel S.;
    • Balgley, Brian M.;
    • Bantscheff, Marcus;
    • Bennett, Keiryn L.;
    • Björling, Erik;
    • Blagoev, Blagoy;
    • Bose, Ron;
    • Brahmachari, Samir K.;
    • Burlingame, Alma S.;
    • Bustelo, Xosé R.;
    • Cagney, Gerard;
    • Cantin, Greg T.;
    • Cardasis, Helene L.;
    • Celis, Julio E.
    Publication type:
    Letter
    15

    Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.

    Published in:
    Nature Biotechnology, 2007, v. 25, n. 9, p. 1035, doi. 10.1038/nbt1328
    By:
    • Bantscheff, Marcus;
    • Eberhard, Dirk;
    • Abraham, Yann;
    • Bastuck, Sonja;
    • Boesche, Markus;
    • Hobson, Scott;
    • Mathieson, Toby;
    • Perrin, Jessica;
    • Raida, Manfred;
    • Rau, Christina;
    • Reader, Valérie;
    • Sweetman, Gavain;
    • Bauer, Andreas;
    • Bouwmeester, Tewis;
    • Hopf, Carsten;
    • Kruse, Ulrich;
    • Neubauer, Gitte;
    • Ramsden, Nigel;
    • Rick, Jens;
    • Kuster, Bernhard
    Publication type:
    Article
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    Mutational Analysis of Glycogen Synthase Kinase 3β Protein Kinase Together with Kinome-Wide Binding and Stability Studies Suggests Context-Dependent Recognition of Kinases by the Chaperone Heat Shock Protein 90.

    Published in:
    Molecular & Cellular Biology, 2016, v. 36, n. 6, p. 1007, doi. 10.1128/MCB.01045-15
    By:
    • Jing Jin;
    • Ruijun Tian;
    • Pasculescu, Adrian;
    • Anna Yue Dai;
    • Williton, Kelly;
    • Lorne Taylor;
    • Savitski, Mikhail M.;
    • Bantscheff, Marcus;
    • Woodgett, James R.;
    • Pawson, Tony;
    • Colwill, Karen
    Publication type:
    Article
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    Drug-perturbation-based stratification of blood cancer.

    Published in:
    2018
    By:
    • Dietrich, Sascha;
    • Oleś, Małgorzata;
    • Junyan Lu;
    • Sellner, Leopold;
    • Anders, Simon;
    • Velten, Britta;
    • Bian Wu;
    • Hüllein, Jennifer;
    • da Silva Liberio, Michelle;
    • Walther, Tatjana;
    • Wagner, Lena;
    • Rabe, Sophie;
    • Ghidelli-Disse, Sonja;
    • Bantscheff, Marcus;
    • Oleś, Andrzej K.;
    • Słabicki, Mikołaj;
    • Mock, Andreas;
    • Oakes, Christopher C.;
    • Shihui Wang;
    • Oppermann, Sina
    Publication type:
    journal article
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    Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs.

    Published in:
    Angewandte Chemie, 2021, v. 133, n. 43, p. 23515, doi. 10.1002/ange.202109237
    By:
    • Law, Robert P.;
    • Nunes, Joao;
    • Chung, Chun‐wa;
    • Bantscheff, Marcus;
    • Buda, Karol;
    • Dai, Han;
    • Evans, John P.;
    • Flinders, Adam;
    • Klimaszewska, Diana;
    • Lewis, Antonia J.;
    • Muelbaier, Marcel;
    • Scott‐Stevens, Paul;
    • Stacey, Peter;
    • Tame, Christopher J.;
    • Watt, Gillian F.;
    • Zinn, Nico;
    • Queisser, Markus A.;
    • Harling, John D.;
    • Benowitz, Andrew B.
    Publication type:
    Article
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    Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 387, p. 1, doi. 10.1126/scitranslmed.aad9735
    By:
    • Paquet, Tanya;
    • Le Manach, Claire;
    • González Cabrera, Diego;
    • Younis, Yassir;
    • Henrich, Philipp P.;
    • Abraham, Tara S.;
    • Lee, Marcus C. S.;
    • Basak, Rajshekhar;
    • Ghidelli-Disse, Sonja;
    • Lafuente-Monasterio, María José;
    • Bantscheff, Marcus;
    • Ruecker, Andrea;
    • Blagborough, Andrew M.;
    • Zakutansky, Sara E.;
    • Zeeman, Anne-Marie;
    • White, Karen L.;
    • Shackleford, David M.;
    • Mannila, Janne;
    • Morizzi, Julia;
    • Scheurer, Christian
    Publication type:
    Article
    26

    New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 11, p. 878, doi. 10.1038/nchembio.1930
    By:
    • Okoye-Okafor, Ujunwa C;
    • Bartholdy, Boris;
    • Cartier, Jessy;
    • Gao, Enoch N;
    • Pietrak, Beth;
    • Rendina, Alan R;
    • Rominger, Cynthia;
    • Quinn, Chad;
    • Smallwood, Angela;
    • Wiggall, Kenneth J;
    • Reif, Alexander J;
    • Schmidt, Stanley J;
    • Qi, Hongwei;
    • Zhao, Huizhen;
    • Joberty, Gerard;
    • Faelth-Savitski, Maria;
    • Bantscheff, Marcus;
    • Drewes, Gerard;
    • Duraiswami, Chaya;
    • Brady, Pat
    Publication type:
    Article
    27

    Catalytic in vivo protein knockdown by small-molecule PROTACs.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 8, p. 611, doi. 10.1038/nchembio.1858
    By:
    • Bondeson, Daniel P;
    • Mares, Alina;
    • Smith, Ian E D;
    • Ko, Eunhwa;
    • Campos, Sebastien;
    • Miah, Afjal H;
    • Mulholland, Katie E;
    • Routly, Natasha;
    • Buckley, Dennis L;
    • Gustafson, Jeffrey L;
    • Zinn, Nico;
    • Grandi, Paola;
    • Shimamura, Satoko;
    • Bergamini, Giovanna;
    • Faelth-Savitski, Maria;
    • Bantscheff, Marcus;
    • Cox, Carly;
    • Gordon, Deborah A;
    • Willard, Ryan R;
    • Flanagan, John J
    Publication type:
    Article
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    SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.

    Published in:
    Science Immunology, 2021, v. 6, n. 58, p. 1, doi. 10.1126/sciimmunol.abg0833
    By:
    • Yan, Bingyu;
    • Freiwald, Tilo;
    • Chauss, Daniel;
    • Wang, Luopin;
    • West, Erin;
    • Mirabelli, Carmen;
    • Zhang, Charles J.;
    • Nichols, Eva-Maria;
    • Malik, Nazish;
    • Gregory, Richard;
    • Bantscheff, Marcus;
    • Ghidelli-Disse, Sonja;
    • Kolev, Martin;
    • Frum, Tristan;
    • Spence, Jason R.;
    • Sexton, Jonathan Z.;
    • Alysandratos, Konstantinos D.;
    • Kotton, Darrell N.;
    • Pittaluga, Stefania;
    • Bibby, Jack
    Publication type:
    Article
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    Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.

    Published in:
    Acta Neuropathologica, 2017, v. 133, n. 5, p. 731, doi. 10.1007/s00401-016-1663-9
    By:
    • Wang, Peng;
    • Joberty, Gerard;
    • Buist, Arjan;
    • Vanoosthuyse, Alexandre;
    • Stancu, Ilie-Cosmin;
    • Vasconcelos, Bruno;
    • Pierrot, Nathalie;
    • Faelth-Savitski, Maria;
    • Kienlen-Campard, Pascal;
    • Octave, Jean-Noël;
    • Bantscheff, Marcus;
    • Drewes, Gerard;
    • Moechars, Diederik;
    • Dewachter, Ilse
    Publication type:
    Article
    36

    Mass-spectrometry-based draft of the human proteome.

    Published in:
    Nature, 2014, v. 509, n. 7502, p. 1, doi. 10.1038/nature13319
    By:
    • Wilhelm, Mathias;
    • Schlegl, Judith;
    • Hahne, Hannes;
    • Gholami, Amin Moghaddas;
    • Lieberenz, Marcus;
    • Savitski, Mikhail M.;
    • Ziegler, Emanuel;
    • Butzmann, Lars;
    • Gessulat, Siegfried;
    • Marx, Harald;
    • Mathieson, Toby;
    • Lemeer, Simone;
    • Schnatbaum, Karsten;
    • Reimer, Ulf;
    • Wenschuh, Holger;
    • Mollenhauer, Martin;
    • Slotta-Huspenina, Julia;
    • Boese, Joos-Hendrik;
    • Bantscheff, Marcus;
    • Gerstmair, Anja
    Publication type:
    Article
    37

    A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.

    Published in:
    Nature, 2012, v. 488, n. 7411, p. 404, doi. 10.1038/nature11262
    By:
    • Kruidenier, Laurens;
    • Chung, Chun-wa;
    • Cheng, Zhongjun;
    • Liddle, John;
    • Che, KaHing;
    • Joberty, Gerard;
    • Bantscheff, Marcus;
    • Bountra, Chas;
    • Bridges, Angela;
    • Diallo, Hawa;
    • Eberhard, Dirk;
    • Hutchinson, Sue;
    • Jones, Emma;
    • Katso, Roy;
    • Leveridge, Melanie;
    • Mander, Palwinder K.;
    • Mosley, Julie;
    • Ramirez-Molina, Cesar;
    • Rowland, Paul;
    • Schofield, Christopher J.
    Publication type:
    Article
    38

    Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.

    Published in:
    Nature, 2011, v. 478, n. 7370, p. 529, doi. 10.1038/nature10509
    By:
    • Dawson, Mark A.;
    • Prinjha, Rab K.;
    • Dittmann, Antje;
    • Giotopoulos, George;
    • Bantscheff, Marcus;
    • Chan, Wai-In;
    • Robson, Samuel C.;
    • Chung, Chun-wa;
    • Hopf, Carsten;
    • Savitski, Mikhail M.;
    • Huthmacher, Carola;
    • Gudgin, Emma;
    • Lugo, Dave;
    • Beinke, Soren;
    • Chapman, Trevor D.;
    • Roberts, Emma J.;
    • Soden, Peter E.;
    • Auger, Kurt R.;
    • Mirguet, Olivier;
    • Doehner, Konstanze
    Publication type:
    Article
    39

    Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2.

    Published in:
    Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0868-6
    By:
    • Mares, Alina;
    • Miah, Afjal H.;
    • Smith, Ian E. D.;
    • Rackham, Mark;
    • Thawani, Aditya R.;
    • Cryan, Jenni;
    • Haile, Pamela A.;
    • Votta, Bartholomew J.;
    • Beal, Allison M.;
    • Capriotti, Carol;
    • Reilly, Michael A.;
    • Fisher, Don T.;
    • Zinn, Nico;
    • Bantscheff, Marcus;
    • MacDonald, Thomas T.;
    • Vossenkamper, Anna;
    • Dace, Phoebe;
    • Churcher, Ian;
    • Benowitz, Andrew B.;
    • Watt, Gillian
    Publication type:
    Article
    40

    Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines.

    Published in:
    G3: Genes | Genomes | Genetics, 2020, v. 10, n. 5, p. 1585, doi. 10.1534/g3.119.401031
    By:
    • Mueller, William F.;
    • Jakob, Petra;
    • Han Sun;
    • Clauder-Münster, Sandra;
    • Ghidelli-Disse, Sonja;
    • Ordonez, Diana;
    • Boesche, Markus;
    • Bantscheff, Marcus;
    • Collier, Paul;
    • Haase, Bettina;
    • Benes, Vladimir;
    • Paulsen, Malte;
    • Sehr, Peter;
    • Lewis, Joe;
    • Drewes, Gerard;
    • Steinmetz, Lars M.
    Publication type:
    Article
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