Works by Maragakis, Nicholas J.


Results: 50
    1

    Reldesemtiv in Amyotrophic Lateral Sclerosis: Results From the COURAGE-ALS Randomized Clinical Trial.

    Published in:
    JAMA Neurology, 2025, v. 82, n. 5, p. 477, doi. 10.1001/jamaneurol.2025.0241
    By:
    • Shefner, Jeremy M.;
    • Cudkowicz, Merit E.;
    • Genge, Angela;
    • Hardiman, Orla;
    • Al-Chalabi, Ammar;
    • Andrews, Jinsy A.;
    • Chio, Adriano;
    • Corcia, Philippe;
    • Couratier, Philippe;
    • de Carvalho, Mamede;
    • Heiman-Patterson, Terry;
    • Henderson, Robert D.;
    • Ingre, Caroline;
    • Johnston, Wendy;
    • Ludolph, Albert;
    • Maragakis, Nicholas J.;
    • Miller, Timothy M.;
    • Mora, Jesus S.;
    • Petri, Susanne;
    • Simmons, Zachary
    Publication type:
    Article
    2

    Stable Decoding from a Speech BCI Enables Control for an Individual with ALS without Recalibration for 3 Months.

    Published in:
    Advanced Science, 2023, v. 10, n. 35, p. 1, doi. 10.1002/advs.202304853
    By:
    • Luo, Shiyu;
    • Angrick, Miguel;
    • Coogan, Christopher;
    • Candrea, Daniel N.;
    • Wyse‐Sookoo, Kimberley;
    • Shah, Samyak;
    • Rabbani, Qinwan;
    • Milsap, Griffin W.;
    • Weiss, Alexander R.;
    • Anderson, William S.;
    • Tippett, Donna C.;
    • Maragakis, Nicholas J.;
    • Clawson, Lora L.;
    • Vansteensel, Mariska J.;
    • Wester, Brock A.;
    • Tenore, Francesco V.;
    • Hermansky, Hynek;
    • Fifer, Matthew S.;
    • Ramsey, Nick F.;
    • Crone, Nathan E.
    Publication type:
    Article
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    Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.

    Published in:
    JAMA Neurology, 2021, v. 78, n. 2, p. 186, doi. 10.1001/jamaneurol.2020.4300
    By:
    • Wainger, Brian J.;
    • Macklin, Eric A.;
    • Vucic, Steve;
    • McIlduff, Courtney E.;
    • Paganoni, Sabrina;
    • Maragakis, Nicholas J.;
    • Bedlack, Richard;
    • Goyal, Namita A.;
    • Rutkove, Seward B.;
    • Lange, Dale J.;
    • Rivner, Michael H.;
    • Goutman, Stephen A.;
    • Ladha, Shafeeq S.;
    • Mauricio, Elizabeth A.;
    • Baloh, Robert H.;
    • Simmons, Zachary;
    • Pothier, Lindsay;
    • Kassis, Sylvia Baedorf;
    • La, Thuong;
    • Hall, Meghan
    Publication type:
    Article
    5

    Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis.

    Published in:
    Glia (0894-1491), 2016, v. 64, n. 8, p. 1298, doi. 10.1002/glia.23003
    By:
    • Qosa, Hisham;
    • Lichter, Jessica;
    • Sarlo, Mark;
    • Markandaiah, Shashirekha S.;
    • McAvoy, Kevin;
    • Richard, Jean‐Philippe;
    • Jablonski, Michael R.;
    • Maragakis, Nicholas J.;
    • Pasinelli, Piera;
    • Trotti, Davide
    Publication type:
    Article
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    MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.

    Published in:
    Journal of Neuroscience, 2017, v. 37, n. 22, p. 5574, doi. 10.1523/JNEUROSCI.3582-16.2017
    By:
    • Hoye, Mariah L.;
    • Koval, Erica D.;
    • Wegener, Amy J.;
    • Hyman, Theodore S.;
    • Chengran Yang;
    • O'Brien, David R.;
    • Miller, Rebecca L.;
    • Cole, Tracy;
    • Schoch, Kathleen M.;
    • Tao Shen;
    • Tomonori Kunikata;
    • Richard, Jean-Philippe;
    • Gutmann, David H.;
    • Maragakis, Nicholas J.;
    • Kordasiewicz, Holly B.;
    • Dougherty, Joseph D.;
    • Miller, Timothy M.
    Publication type:
    Article
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    C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

    Published in:
    Nature, 2014, v. 507, n. 7491, p. 195, doi. 10.1038/nature13124
    By:
    • Haeusler, Aaron R.;
    • Donnelly, Christopher J.;
    • Periz, Goran;
    • Simko, Eric A. J.;
    • Shaw, Patrick G.;
    • Kim, Min-Sik;
    • Maragakis, Nicholas J.;
    • Troncoso, Juan C.;
    • Pandey, Akhilesh;
    • Sattler, Rita;
    • Rothstein, Jeffrey D.;
    • Wang, Jiou
    Publication type:
    Article
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    Olfactory dysfunction in amyotrophic lateral sclerosis.

    Published in:
    Annals of Clinical & Translational Neurology, 2018, v. 5, n. 8, p. 976, doi. 10.1002/acn3.594
    By:
    • Viguera, Cristina;
    • Wang, Jiangxia;
    • Mosmiller, Elizabeth;
    • Cerezo, Aiana;
    • Maragakis, Nicholas J.
    Publication type:
    Article
    27

    Multimodal Actions of Neural Stem Cells in a Mouse Model of ALS: A Meta-Analysis.

    Published in:
    Science Translational Medicine, 2012, v. 4, n. 165, p. 1, doi. 10.1126/scitranslmed.3004579
    By:
    • Teng, Yang D.;
    • Benn, Susanna C.;
    • Kalkanis, Steven N.;
    • Shefner, Jeremy M.;
    • Onario, Renna C.;
    • Bin Cheng;
    • Lachyankar, Mahesh B.;
    • Marconi, Michael;
    • Jianxue Li;
    • Dou Yu;
    • Han, Inbo;
    • Maragakis, Nicholas J.;
    • Lládo, Jeronia;
    • Erkmen, Kadir;
    • Redmond Jr., D. Eugene;
    • Sidman, Richard L.;
    • Przedborski, Serge;
    • Rothstein, Jeffrey D.;
    • Brown Jr., Robert H.;
    • Snyder, Evan Y.
    Publication type:
    Article
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    Exome sequencing to identify de novo mutations in sporadic ALS trios.

    Published in:
    Nature Neuroscience, 2013, v. 16, n. 7, p. 851, doi. 10.1038/nn.3412
    By:
    • Chesi, Alessandra;
    • Staahl, Brett T;
    • Jovičić, Ana;
    • Couthouis, Julien;
    • Fasolino, Maria;
    • Raphael, Alya R;
    • Yamazaki, Tomohiro;
    • Elias, Laura;
    • Polak, Meraida;
    • Kelly, Crystal;
    • Williams, Kelly L;
    • Fifita, Jennifer A;
    • Maragakis, Nicholas J;
    • Nicholson, Garth A;
    • King, Oliver D;
    • Reed, Robin;
    • Crabtree, Gerald R;
    • Blair, Ian P;
    • Glass, Jonathan D;
    • Gitler, Aaron D
    Publication type:
    Article
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    Electrical impedance myography correlates with standard measures of Als severity.

    Published in:
    Muscle & Nerve, 2014, v. 49, n. 3, p. 441, doi. 10.1002/mus.24128
    By:
    • Rutkove, Seward B.;
    • Caress, James B.;
    • Cartwright, Michael S.;
    • Burns, Ted M.;
    • Warder, Judy;
    • David, William S.;
    • Goyal, Namita;
    • Maragakis, Nicholas J.;
    • Benatar, Michael;
    • Sharma, Khema R.;
    • Narayanaswami, Pushpa;
    • Raynor, Elizabeth M.;
    • Watson, Mary Lou;
    • Shefner, Jeremy M.
    Publication type:
    Article
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    Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.

    Published in:
    Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0217-5
    By:
    • Konrad, Csaba;
    • Hibiki Kawamata;
    • Bredvik, Kirsten G.;
    • Arreguin, Andrea J.;
    • Cajamarca, Steven A.;
    • Hupf, Jonathan C.;
    • Ravits, John M.;
    • Miller, Timothy M.;
    • Maragakis, Nicholas J.;
    • Hales, Chadwick M.;
    • Glass, Jonathan D.;
    • Gross, Steven;
    • Hiroshi Mitsumoto;
    • Manfredi, Giovanni
    Publication type:
    Article
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    COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success.

    Published in:
    Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2023, v. 24, n. 5/6, p. 523, doi. 10.1080/21678421.2023.2216223
    By:
    • Shefner, Jeremy M.;
    • Al-Chalabi, Ammar;
    • Andrews, Jinsy A.;
    • Chio, Adriano;
    • De Carvalho, Mamede;
    • Cockroft, Bettina M.;
    • Corcia, Philippe;
    • Couratier, Philippe;
    • Cudkowicz, Merit E.;
    • Genge, Angela;
    • Hardiman, Orla;
    • Heiman-Patterson, Terry;
    • Henderson, Robert D.;
    • Ingre, Caroline;
    • Jackson, Carlayne E.;
    • Johnston, Wendy;
    • Lechtzin, Noah;
    • Ludolph, Albert;
    • Maragakis, Nicholas J.;
    • Miller, Timothy M.
    Publication type:
    Article
    46

    Primary lateral sclerosis natural history study – planning, designing, and early enrollment.

    Published in:
    Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2023, v. 24, n. 5/6, p. 394, doi. 10.1080/21678421.2022.2161912
    By:
    • Mitsumoto, Hiroshi;
    • Jang, Grace;
    • Lee, Ikjae;
    • Simmons, Zachary;
    • Sherman, Alexander V.;
    • Heitzman, Daragh;
    • Sorenson, Eric;
    • Cheung, Ken;
    • Andrews, Jinsy;
    • Harms, Matthew;
    • Shneider, Neil A.;
    • Santella, Regina;
    • Paganoni, Sabrina;
    • Ajroud-Driss, Senda;
    • Fernandes, J. Americo M.;
    • Burke, Katherine M.;
    • Gwathmey, Kelly;
    • Habib, Ali A.;
    • Maragakis, Nicholas J.;
    • Walk, David
    Publication type:
    Article
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    CNM-Au8 in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial.

    Published in:
    JAMA: Journal of the American Medical Association, 2025, v. 333, n. 13, p. 1138, doi. 10.1001/jama.2024.27643
    By:
    • Berry, James D.;
    • Maragakis, Nicholas J.;
    • Macklin, Eric A.;
    • Chibnik, Lori B.;
    • Quintana, Melanie;
    • Saville, Benjamin R.;
    • Detry, Michelle A.;
    • Vestrucci, Matteo;
    • Marion, Joseph;
    • McGlothlin, Anna;
    • Stommel, Elijah W.;
    • Chase, Marianne;
    • Pothier, Lindsay;
    • Harkey, Brittney A.;
    • Yu, Hong;
    • Sherman, Alex;
    • Shefner, Jeremy;
    • Hall, Meghan;
    • Kittle, Gale;
    • Babu, Suma
    Publication type:
    Article