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Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients.
Published in:
2008
By:
- Howe, Steven J.;
- Mansour, Marc R.;
- Schwarzwaelder, Kerstin;
- Bartholomae, Cynthia;
- Hubank, Michael;
- Kempski, Helena;
- Brugman, Martijn H.;
- Pike-Overzet, Karin;
- Chatters, Stephen J.;
- de Ridder, Dick;
- Gilmour, Kimberly C.;
- Adams, Stuart;
- Thornhill, Susannah I.;
- Parsley, Kathryn L.;
- Staal, Frank J.T.;
- Gale, Rosemary E.;
- Linch, David C.;
- Bayford, Jinhua;
- Brown, Lucie;
- Quaye, Michelle
Publication type:
journal article
Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP- related domain.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.14713
By:
- Shuning He;
- Mansour, Marc R.;
- Zimmerman, Mark W.;
- Dong Hyuk Ki;
- Layden, Hillary M.;
- Koshi Akahane;
- Gjini, Evisa;
- de Groh, Eric D.;
- Perez-Atayde, Antonio R.;
- Shizhen Zhu;
- Epstein, Jonathan A.;
- Look, A. Thomas
Publication type:
Article
Current and emerging therapeutic approaches for T‐cell acute lymphoblastic leukaemia.
Published in:
British Journal of Haematology, 2021, v. 194, n. 1, p. 28, doi. 10.1111/bjh.17310
By:
- Pocock, Rachael;
- Farah, Nadine;
- Richardson, Simon E.;
- Mansour, Marc R.
Publication type:
Article
Successful remission induction therapy with gilteritinib in a patient with de novo FLT3‐mutated acute myeloid leukaemia and severe COVID‐19.
Published in:
British Journal of Haematology, 2020, v. 190, n. 4, p. e189, doi. 10.1111/bjh.16962
By:
- Wilson, Andrew J.;
- Troy‐Barnes, Ethan;
- Subhan, Maryam;
- Clark, Fiona;
- Gupta, Rajeev;
- Fielding, Adele K.;
- Kottaridis, Panagiotis;
- Mansour, Marc R.;
- O'Nions, Jenny;
- Payne, Elspeth;
- Chavda, Naina;
- Baker, Robert;
- Thomson, Kirsty;
- Khwaja, Asim
Publication type:
Article
In trans early mosaic mutational escape and novel phenotypic features of germline SAMD9 mutation.
Published in:
British Journal of Haematology, 2020, v. 188, n. 4, p. e53, doi. 10.1111/bjh.16322
By:
- Hockings, Catherine;
- Gohil, Satyen;
- Dowse, Robin;
- Hoade, Yvette;
- Mansour, Marc R.;
- Gale, Rosemary E.;
- Linch, David C.;
- Rao, Anupama;
- Payne, Elspeth M.
Publication type:
Article
Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia.
Published in:
British Journal of Haematology, 2015, v. 168, n. 2, p. 230, doi. 10.1111/bjh.13115
By:
- Mansour, Marc R.;
- Reed, Casie;
- Eisenberg, Amy R.;
- Tseng, Jen ‐ Chieh;
- Twizere, Jean ‐ Claude;
- Daakour, Sarah;
- Yoda, Akinori;
- Rodig, Scott J.;
- Tal, Noa;
- Shochat, Chen;
- Berezovskaya, Alla;
- DeAngelo, Daniel J.;
- Sallan, Stephen E.;
- Weinstock, David M.;
- Izraeli, Shai;
- Kung, Andrew L.;
- Kentsis, Alex;
- Look, A. Thomas
Publication type:
Article
Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma.
Published in:
Cancers, 2023, v. 15, n. 3, p. 647, doi. 10.3390/cancers15030647
By:
- Provez, Lien;
- Putteman, Tom;
- Landfors, Mattias;
- Roels, Juliette;
- Reunes, Lindy;
- T'Sas, Sara;
- Van Loocke, Wouter;
- Lintermans, Béatrice;
- De Coninck, Stien;
- Thenoz, Morgan;
- Sleeckx, Wouter;
- Maćkowska-Maślak, Natalia;
- Taghon, Tom;
- Mansour, Marc R.;
- Farah, Nadine;
- Norga, Koen;
- Vandenberghe, Peter;
- Kotecha, Rishi S.;
- Goossens, Steven;
- Degerman, Sofie
Publication type:
Article
Cyclin C is a haploinsufficient tumour suppressor.
Published in:
Nature Cell Biology, 2014, v. 16, n. 11, p. 1080, doi. 10.1038/ncb3046
By:
- Li, Na;
- Fassl, Anne;
- Chick, Joel;
- Inuzuka, Hiroyuki;
- Li, Xiaoyu;
- Mansour, Marc R.;
- Liu, Lijun;
- Wang, Haizhen;
- King, Bryan;
- Shaik, Shavali;
- Gutierrez, Alejandro;
- Ordureau, Alban;
- Otto, Tobias;
- Kreslavsky, Taras;
- Baitsch, Lukas;
- Bury, Leah;
- Meyer, Clifford A.;
- Ke, Nan;
- Mulry, Kristin A.;
- Kluk, Michael J.
Publication type:
Article
Corrigendum: Small genomic insertions form enhancers that misregulate oncogenes.
Published in:
Nature Communications, 2017, v. 8, n. 6, p. 15797, doi. 10.1038/ncomms15797
By:
- Abraham, Brian J.;
- Hnisz, Denes;
- Weintraub, Abraham S.;
- Kwiatkowski, Nicholas;
- Li, Charles H.;
- Li, Zhaodong;
- Weichert-Leahey, Nina;
- Rahman, Sunniyat;
- Liu, Yu;
- Etchin, Julia;
- Li, Benshang;
- Shen, Shuhong;
- Lee, Tong Ihn;
- Zhang, Jinghui;
- Look, A. Thomas;
- Mansour, Marc R.;
- Young, Richard A.
Publication type:
Article
Small genomic insertions form enhancers that misregulate oncogenes.
Published in:
Nature Communications, 2017, v. 8, n. 2, p. 14385, doi. 10.1038/ncomms14385
By:
- Abraham, Brian J.;
- Hnisz, Denes;
- Weintraub, Abraham S.;
- Kwiatkowski, Nicholas;
- Li, Charles H.;
- Li, Zhaodong;
- Weichert-Leahey, Nina;
- Rahman, Sunniyat;
- Liu, Yu;
- Etchin, Julia;
- Li, Benshang;
- Shen, Shuhong;
- Lee, Tong Ihn;
- Zhang, Jinghui;
- Look, A. Thomas;
- Mansour, Marc R.;
- Young, Richard A.
Publication type:
Article
KPT-330 inhibitor of CRM1 ( XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia.
Published in:
British Journal of Haematology, 2013, v. 161, n. 1, p. 117, doi. 10.1111/bjh.12231
By:
- Etchin, Julia;
- Sanda, Takaomi;
- Mansour, Marc R.;
- Kentsis, Alex;
- Montero, Joan;
- Le, Bonnie T.;
- Christie, Amanda L.;
- McCauley, Dilara;
- Rodig, Scott J.;
- Kauffman, Michael;
- Shacham, Sharon;
- Stone, Richard;
- Letai, Anthony;
- Kung, Andrew L.;
- Thomas Look, A.
Publication type:
Article

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