Works by Mansell, Ashley

Results: 47

A novel function of InlB from Listeria monocytogenes: activation of NF-κB in J774 macrophages.

Published in:

Cellular Microbiology, 2000, v. 2, n. 2, p. 127, doi. 10.1046/j.1462-5822.2000.00038.x

By:

Mansell, Ashley;
Braun, Laurence;
Cossart, Pascale;
O'neill, Luke A. J.

Publication type:

Article

Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation.

Published in:

Journal of Inflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12950-023-00365-8

By:

Barry, Kristian;
Harpur, Christopher;
Lam, Maggie;
Tate, Michelle D.;
Mansell, Ashley

Publication type:

Article

Evaluation of inflammation and follicle depletion during ovarian ageing in mice.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79488-4

By:

Lliberos, Carolina;
Liew, Seng H.;
Zareie, Pirooz;
La Gruta, Nicole L.;
Mansell, Ashley;
Hutt, Karla

Publication type:

Article

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04581-2

By:

Lee, Jacinta P. W.;
Fan, Huapeng;
Deen, Nadia S.;
Morand, Eric F.;
Harris, James;
Tali Lang;
Pinar, Anita A.;
Mueller, Ivo;
Stanisic, Danielle;
Baiwog, Francesca S.;
Skene, Colin;
Elgass, Kirstin;
Creed, Sarah J.;
Tate, Michelle D.;
Mansell, Ashley;
Aitken, Elizabeth H.;
Wilce, Matthew C. J.;
Traore, Daouda A. K.

Publication type:

Article

Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection.

Published in:

Cell Death & Disease, 2023, v. 14, n. 11, p. 1, doi. 10.1038/s41419-023-06258-1

By:

Rosli, Sarah;
Harpur, Christopher M.;
Lam, Maggie;
West, Alison C.;
Hodges, Christopher;
Mansell, Ashley;
Lawlor, Kate E.;
Tate, Michelle D.

Publication type:

Article

Circulating BiP/Grp78 is a novel prognostic marker for sepsis‐mediated immune cell death.

Published in:

FEBS Journal, 2021, v. 288, n. 6, p. 1809, doi. 10.1111/febs.15552

By:

Doerflinger, Marcel;
Reljic, Boris;
Menassa, Joseph;
Nedeva, Christina;
Jose, Irvin;
Faou, Pierre;
Mackiewicz, Liana;
Mansell, Ashley;
Pellegrini, Marc;
Hotchkiss, Richard;
Puthalakath, Hamsa

Publication type:

Article

A type III effector antagonizes death receptor signalling during bacterial gut infection.

Published in:

Nature, 2013, v. 501, n. 7466, p. 247, doi. 10.1038/nature12524

By:

Pearson, Jaclyn S.;
Giogha, Cristina;
Ong, Sze Ying;
Kennedy, Catherine L.;
Kelly, Michelle;
Robinson, Keith S.;
Lung, Tania Wong Fok;
Mansell, Ashley;
Riedmaier, Patrice;
Oates, Clare V. L.;
Zaid, Ali;
Mühlen, Sabrina;
Crepin, Valerie F.;
Marches, Olivier;
Ang, Ching-Seng;
Williamson, Nicholas A.;
O'Reilly, Lorraine A.;
Bankovacki, Aleksandra;
Nachbur, Ueli;
Infusini, Giuseppe

Publication type:

Article

Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia.

Published in:

BMC Microbiology, 2008, v. 8, p. 1, doi. 10.1186/1471-2180-8-39

By:

Howden, Benjamin P.;
Smith, Danielle J.;
Mansell, Ashley;
Johnson, Paul D. R.;
Ward, Peter B.;
Stinear, Timothy P.;
Davies, John K.

Publication type:

Article

NLRP1- A CINDERELLA STORY: a perspective of recent advances in NLRP1 and the questions they raise.

Published in:

Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05684-3

By:

Barry, Kristian;
Murphy, Christopher;
Mansell, Ashley

Publication type:

Article

Cherry Valley Ducks Mitochondrial Antiviral-Signaling Protein-Mediated Signaling Pathway and antiviral activity research.

Published in:

Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00377

By:

Ning Li;
Tianqi Hong;
Rong Li;
Yao Wang;
Mengjiao Guo;
Zongxi Cao;
Yumei Cai;
Sidang Liu;
Tongjie Chai;
Liangmeng Wei;
Mansell, Ashley;
Brien, James Drew

Publication type:

Article

Insights into Soluble Toll-Like Receptor 2 as a Downregulator of Virally Induced Inflammation.

Published in:

Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00291

By:

Henrick, Bethany M.;
Xiao-Dan Yao;
Taha, Ameer Y.;
German, J. Bruce;
Rosenthal, Kenneth Lee;
Mansell, Ashley;
Kumar, Arun

Publication type:

Article

Innate immune programing by endotoxin and its pathological consequences.

Published in:

Frontiers in Immunology, 2015, v. 5, p. 1, doi. 10.3389/fimmu.2014.00680

By:

Morris, Matthew C.;
Gilliam, Elizabeth A.;
Liwu Li;
Pucillo, Carlo;
Mansell, Ashley

Publication type:

Article

Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension.

Published in:

Cardiovascular Research, 2019, v. 115, n. 4, p. 776, doi. 10.1093/cvr/cvy252

By:

Krishnan, Shalini M;
Ling, Yeong H;
Huuskes, Brooke M;
Ferens, Dorota M;
Saini, Narbada;
Chan, Christopher T;
Diep, Henry;
Kett, Michelle M;
Samuel, Chrishan S;
Kemp-Harper, Barbara K;
Robertson, Avril A B;
Cooper, Matthew A;
Peter, Karlheinz;
Latz, Eicke;
Mansell, Ashley S;
Sobey, Christopher G;
Drummond, Grant R;
Vinh, Antony

Publication type:

Article

Interleukin‐1β exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection.

Published in:

Immunology & Cell Biology, 2021, v. 99, n. 7, p. 737, doi. 10.1111/imcb.12459

By:

Bawazeer, Abdulah OS;
Rosli, Sarah;
Harpur, Christopher M;
Docherty, Callum AH;
Mansell, Ashley;
Tate, Michelle D

Publication type:

Article

Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase‐5 in human monocytes.

Published in:

Immunology & Cell Biology, 2018, v. 96, n. 10, p. 1120, doi. 10.1111/imcb.12190

By:

Bitto, Natalie J;
Baker, Paul J;
Dowling, Jennifer K;
Wray‐McCann, Georgie;
De Paoli, Amanda;
Tran, Le Son;
Leung, Pak Ling;
Stacey, Katryn J;
Mansell, Ashley;
Masters, Seth L;
Ferrero, Richard L

Publication type:

Article

Induction of memory cytotoxic T cells to influenza A virus and subsequent viral clearance is not modulated by PB1-F2-dependent inflammasome activation.

Published in:

Immunology & Cell Biology, 2016, v. 94, n. 5, p. 439, doi. 10.1038/icb.2015.115

By:

Lee, Patricia (Hoi Yee);
Bird, Nicola;
MacKenzie‐Kludas, Charley;
Mansell, Ashley;
Kedzierska, Katherine;
Brown, Lorena;
McAuley, Julie

Publication type:

Article

STAT1 plays a role in TLR signal transduction and inflammatory responses.

Published in:

Immunology & Cell Biology, 2014, v. 92, n. 9, p. 761, doi. 10.1038/icb.2014.51

By:

Luu, Kevin;
Greenhill, Claire J;
Majoros, Andrea;
Decker, Thomas;
Jenkins, Brendan J;
Mansell, Ashley

Publication type:

Article

Mitochondrially localised MUL1 is a novel modulator of antiviral signaling.

Published in:

Immunology & Cell Biology, 2013, v. 91, n. 4, p. 321, doi. 10.1038/icb.2013.7

By:

Jenkins, Kristie;
Khoo, Jing Jing;
Sadler, Anthony;
Piganis, Rebecca;
Wang, Die;
Borg, Natalie A;
Hjerrild, Kathryn;
Gould, Jodee;
Thomas, Belinda J;
Nagley, Phillip;
Hertzog, Paul J;
Mansell, Ashley

Publication type:

Article

LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.

Published in:

Immunology & Cell Biology, 2012, v. 90, n. 5, p. 564, doi. 10.1038/icb.2012.25

By:

Greenhill, Claire J;
Gould, Jodee;
Ernst, Matthias;
Jarnicki, Andrew;
Hertzog, Paul J;
Mansell, Ashley;
Jenkins, Brendan J

Publication type:

Article

LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.

Published in:

Immunology & Cell Biology, 2012, v. 90, n. 5, p. 559, doi. 10.1038/icb.2011.56

By:

Greenhill, Claire J;
Gould, Jodee;
Ernst, Matthias;
Jarnicki, Andrew;
Hertzog, Paul J;
Mansell, Ashley;
Jenkins, Brendan J

Publication type:

Article

The negative regulation of Toll-like receptor and associated pathways.

Published in:

Immunology & Cell Biology, 2007, v. 85, n. 6, p. 425, doi. 10.1038/sj.icb.7100094

By:

Lang, Tali;
Mansell, Ashley

Publication type:

Article

Life is so much easier for the sea urchin.

Published in:

Immunology & Cell Biology, 2007, v. 85, n. 6, p. 404, doi. 10.1038/sj.icb.7100096

By:

Mansell, Ashley

Publication type:

Article

The Australian Toll-way gets the Nod—meeting report of TLROZ 2007: pattern recognition receptors in immunity and disease, Melbourne, Australia, 16–18th May 2007.

Published in:

Immunology & Cell Biology, 2007, v. 85, n. 6, p. 401, doi. 10.1038/sj.icb.7100101

By:

Sweet, Matthew J.;
Mansell, Ashley;
Wilson, Trevor J.

Publication type:

Article

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Published in:

Nature, 2001, v. 413, n. 6851, p. 78, doi. 10.1038/35092578

By:

Fitzgerald, Katherine A.;
Palsson-McDermott, Eva M.;
Bowie, Andrew G.;
Jefferies, Caroline A.;
Mansell, Ashley S.;
Brady, Gareth;
Brint, Elizabeth;
Dunne, Aisling;
Gray, Pearl;
Harte, Mary T.;
McMurray, Diane;
Smith, Dirk E.;
Sims, John E.;
Bird, Timothy A.

Publication type:

Article

Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01017

By:

Cecil, Jessica D.;
O'Brien-Simpson, Neil M.;
Lenzo, Jason C.;
Holden, James A.;
Singleton, William;
Perez-Gonzalez, Alexis;
Mansell, Ashley;
Reynolds, Eric C.

Publication type:

Article

Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection.

Published in:

2019

By:

Rosli, Sarah;
Kirby, Francis J.;
Lawlor, Kate E.;
Rainczuk, Kate;
Drummond, Grant R.;
Mansell, Ashley;
Tate, Michelle D.

Publication type:

journal article

Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines.

Published in:

International Immunology, 2006, v. 18, n. 12, p. 1801, doi. 10.1093/intimm/dxl114

By:

Lau, Yuk Fai;
Deliyannis, Georgia;
Zeng, Weiguang;
Mansell, Ashley;
Jackson, David C.;
Brown, Lorena E.

Publication type:

Article

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.

Published in:

Nature Communications, 2015, v. 6, n. 4, p. 6795, doi. 10.1038/ncomms7795

By:

Sadler, Anthony J.;
Suliman, Bandar A.;
Yu, Liang;
Yuan, Xiangliang;
Wang, Die;
Irving, Aaron T.;
Sarvestani, Soroush T.;
Banerjee, Ashish;
Mansell, Ashley S.;
Liu, Jun-Ping;
Gerondakis, Steve;
Williams, Bryan R. G.;
Xu, Dakang

Publication type:

Article

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

Published in:

PLoS Pathogens, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.ppat.1003392

By:

McAuley, Julie L.;
Tate, Michelle D.;
MacKenzie-Kludas, Charley J.;
Pinar, Anita;
Zeng, Weiguang;
Stutz, Andrea;
Latz, Eicke;
Brown, Lorena E.;
Mansell, Ashley

Publication type:

Article

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition.

Published in:

Scientific Reports, 2016, p. 27912, doi. 10.1038/srep27912

By:

Tate, Michelle D.;
Ong, James D. H.;
Dowling, Jennifer K.;
McAuley, Julie L.;
Robertson, Avril B.;
Latz, Eicke;
Drummond, Grant R.;
Cooper, Matthew A.;
Hertzog, Paul J.;
Mansell, Ashley

Publication type:

Article

IL11 activates the placental inflammasome to drive preeclampsia.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1175926

By:

Menkhorst, Ellen;
Santos, Leilani L.;
Wei Zhou;
Guannan Yang;
Winship, Amy L.;
Rainczuk, Katarzyna E.;
Nguyen, Philana;
Jian-Guo Zhang;
Moore, Paddy;
Williams, Michelle;
Kim-Anh LêCao;
Mansell, Ashley;
Dimitriadis, Evdokia

Publication type:

Article

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17669-5

By:

Balic, Jesse J.;
Albargy, Hassan;
Luu, Kevin;
Kirby, Francis J.;
Jayasekara, W. Samantha N.;
Mansell, Finbar;
Garama, Daniel J.;
De Nardo, Dominic;
Baschuk, Nikola;
Louis, Cynthia;
Humphries, Fiachra;
Fitzgerald, Katherine;
Latz, Eicke;
Gough, Daniel J.;
Mansell, Ashley

Publication type:

Article

IRF7 in the Australian Black Flying Fox, <i>Pteropus alecto</i>: Evidence for a Unique Expression Pattern and Functional Conservation.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0103875

By:

Zhou, Peng;
Cowled, Chris;
Mansell, Ashley;
Monaghan, Paul;
Green, Diane;
Wu, Lijun;
Shi, Zhengli;
Wang, Lin-Fa;
Baker, Michelle L.

Publication type:

Article

MyD88 Is a Critical Regulator of Hematopoietic Cell-Mediated Neuroprotection Seen after Stroke.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057948

By:

Downes, Catherine E.;
Wong, Connie H. Y.;
Henley, Katya J.;
Guio-Aguilar, Pedro L.;
Zhang, Moses;
Ates, Robert;
Mansell, Ashley;
Kile, Benjamin T.;
Crack, Peter J.

Publication type:

Article

A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases.

Published in:

Clinical & Translational Immunology, 2023, v. 12, n. 6, p. 1, doi. 10.1002/cti2.1455

By:

Docherty, Callum AH;
Fernando, Anuruddika J;
Rosli, Sarah;
Lam, Maggie;
Dolle, Roland E;
Navia, Manuel A;
Farquhar, Ronald;
La France, Danny;
Tate, Michelle D;
Murphy, Christopher K;
Rossi, Adriano G;
Mansell, Ashley

Publication type:

Article

Parsing the IL-37-Mediated Suppression of Inflammasome Function.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010178

By:

Rudloff, Ina;
Ung, Holly K.;
Dowling, Jennifer K.;
Mansell, Ashley;
D’Andrea, Laura;
Ellisdon, Andrew M.;
Whisstock, James C.;
Berger, Philip J.;
Nold-Petry, Claudia A.;
Nold, Marcel F.

Publication type:

Article

Endogenous macrophage migration inhibitory factor modulates glucocorticoid sensitivity in macrophages via effects on MAP kinase phosphatase-1 and p38 MAP kinase

Published in:

FEBS Letters, 2006, v. 580, n. 3, p. 974, doi. 10.1016/j.febslet.2006.01.027

By:

Aeberli, Daniel;
Yang, Yuan;
Mansell, Ashley;
Santos, Lanie;
Leech, Michelle;
Morand, Eric F.

Publication type:

Article

Another One Fights the Dust: Targeting the NLRP3 Inflammasome for the Treatment of Silicosis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 6, p. 601, doi. 10.1165/rcmb.2021-0545TR

By:

Lam, Maggie;
Mansell, Ashley;
Tate, Michelle D.

Publication type:

Article

Carbonylation Caused by Cigarette Smoke Extract Is Associated with Defective Macrophage Immunity.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2011, v. 45, n. 2, p. 229, doi. 10.1165/rcmb.2010-0272OC

By:

Bozinovski, Steven;
Vlahos, Ross;
Yilin Zhang;
Lin Chin Lah;
Huei Jiunn Seow;
Mansell, Ashley;
Anderson, Gary P.

Publication type:

Article

NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis.

Published in:

Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03192-y

By:

Lam, Maggie;
Barry, Kristian T.;
Hodges, Christopher J.;
Harpur, Christopher M.;
Ong, James D. H.;
Rosli, Sarah;
West, Alison C.;
Dousha, Lovisa;
Hertzog, Paul J.;
Mansell, Ashley;
Tate, Michelle D.

Publication type:

Article

Sculpting the immune response to infection.

Published in:

Nature Immunology, 2011, v. 12, n. 7, p. 579, doi. 10.1038/ni0711-579

By:

Hertzog, Paul J;
Mansell, Ashley;
van Driel, Ian R;
Hartland, Elizabeth L

Publication type:

Article

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation.

Published in:

Nature Immunology, 2006, v. 7, n. 2, p. 148, doi. 10.1038/ni1299

By:

Mansell, Ashley;
Smith, Rosealee;
Doyle, Sarah L;
Gray, Pearl;
Fenner, Jennifer E;
Crack, Peter J;
Nicholson, Sandra E;
Hilton, Douglas J;
O'Neill, Luke A J;
Hertzog, Paul J

Publication type:

Article

TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3<sup>hi</sup> regulatory T cells.

Published in:

European Journal of Immunology, 2013, v. 43, n. 3, p. 723, doi. 10.1002/eji.201242747

By:

Mittag, Diana;
Varese, Nirupama;
Scholzen, Anja;
Mansell, Ashley;
Barker, Gillian;
Rice, Gregory;
Rolland, Jennifer M.;
O'Hehir, Robyn E.

Publication type:

Article

The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms.

Published in:

Journal of Leukocyte Biology, 2022, v. 111, n. 2, p. 327, doi. 10.1002/JLB.2MR1021-260R

By:

Ramnath, Divya;
Das Gupta, Kaustav;
Wang, Yizhuo;
Abrol, Rishika;
Curson, James E. B.;
Lim, Junxian;
Reid, Robert C.;
Mansell, Ashley;
Blumenthal, Antje;
Karunakaran, Denuja;
Fairlie, David P.;
Sweet, Matthew J.

Publication type:

Article

Hero turned villain: NLRP3 inflammasome‐induced inflammation during influenza A virus infection.

Published in:

Journal of Leukocyte Biology, 2017, v. 101, n. 4, p. 863, doi. 10.1189/jlb.4MR0616-288R

By:

Ong, James D. H.;
Mansell, Ashley;
Tate, Michelle D.

Publication type:

Article

The immune modulatory peptide FhHDM‐1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.

Published in:

FASEB Journal, 2017, v. 31, n. 1, p. 85, doi. 10.1096/fj.201500093r

By:

Alvarado, Raquel;
To, Joyce;
Lund, Maria E.;
Pinar, Anita;
Mansell, Ashley;
Robinson, Mark W.;
O'Brien, Bronwyn A.;
Dalton, John P.;
Donnelly, Sheila

Publication type:

Article

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.

Published in:

FASEB Journal, 2017, v. 31, n. 1, p. 85, doi. 10.1096/fj.201500093R

By:

Alvarado, Raquel;
To, Joyce;
Lund, Maria E.;
Pinar, Anita;
Mansell, Ashley;
Robinson, Mark W.;
O'Brien, Bronwyn A.;
Dalton, John P.;
Donnelly, Sheila

Publication type:

Article