Works by Manning, Gerard

Results: 29

Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration.

Published in:

Biochemical Journal, 2023, v. 480, n. 16, p. 1299, doi. 10.1042/BCJ20220397

By:

Jones, Alexander C.;
Kornev, Alexandr P.;
Jui-Hung Weng;
Manning, Gerard;
Taylor, Susan S.;
Newton, Alexandra C.

Publication type:

Article

Assessment of computational methods for redicting the effects of missense mutations in uman cancers.

Published in:

BMC Genomics, 2013, v. 14, n. Suppl 3, p. 1, doi. 10.1186/1471-2164-14-S3-S7

By:

Gnad, Florian;
Baucom, Albion;
Mukhyala, Kiran;
Manning, Gerard;
Zhang, Zemin

Publication type:

Article

Genomics and evolution of protein phosphatases.

Published in:

Science Signaling, 2017, v. 10, n. 474, p. 1, doi. 10.1126/scisignal.aag1796

By:

Chen, Mark J.;
Dixon, Jack E.;
Manning, Gerard

Publication type:

Article

The Raine Syndrome Protein FAM20C Is a Golgi Kinase That Phosphorylates Bio-Mineralization Proteins.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042988

By:

Ishikawa, Hiroyuki O.;
Xu, Aiguo;
Ogura, Eri;
Manning, Gerard;
Irvine, Kenneth D.;
Giniger, Edward

Publication type:

Article

How the vertebrates were made: selective pruning of a double-duplicated genome.

Published in:

BMC Biology, 2010, v. 8, p. 144, doi. 10.1186/1741-7007-8-144

By:

Manning, Gerard;
Scheeff, Eric

Publication type:

Article

Genomic Survey of Premetazoans Shows Deep Conservation of Cytoplasmic Tyrosine Kinases and Multiple Radiations of Receptor Tyrosine Kinases.

Published in:

Science Signaling, 2012, v. 5, n. 222, p. 1, doi. 10.1126/scisignal.2002733

By:

Suga, Hiroshi;
Dacre, Michael;
de Mendoza, Alex;
Shalchian-Tabrizi, Kamran;
Manning, Gerard;
Ruiz-Trillo, Iñaki

Publication type:

Article

Plk5, a Polo Box Domain-Only Protein with Specific Roles in Neuron Differentiation and Glioblastoma Suppression.

Published in:

Molecular & Cellular Biology, 2011, v. 31, n. 6, p. 1225, doi. 10.1128/MCB.00607-10

By:

de Cárcer, Guillermo;
Escobar, Beatriz;
Higuero, Alonso M.;
García, Laura;
Ansón, Alejandra;
Pérez, Gema;
Mollejo, Manuela;
Manning, Gerard;
Meléndez, Bárbara;
Abad-Rodríguez, José;
Malumbres, Marcos

Publication type:

Article

The Sorcerer II Global Ocean Sampling Expedition: Expanding the Universe of Protein Families.

Published in:

PLoS Biology, 2007, v. 5, n. 3, p. 0432, doi. 10.1371/journal.pbio.0050016

By:

Yooseph, Shibu;
Sutton, Granger;
Rusch, Douglas B.;
Halpern, Aaron L.;
Williamson, Shannon J.;
Remington, Karin;
Eisen, Jonathan A.;
Heidelberg, Karla B.;
Manning, Gerard;
Li, Weizhong;
Jaroszewski, Lukasz;
Cieplak, Piotr;
Miller, Christopher S.;
Li, Huiying;
Mashiyama, Susan T.;
Joachimiak, Marcin P.;
van Belle, Christopher;
Chandonia, John-Marc;
Soergel, David A.;
Zhai, Yufeng

Publication type:

Article

Structural and Functional Diversity of the Microbial Kinome.

Published in:

PLoS Biology, 2007, v. 5, n. 3, p. 0467, doi. 10.1371/journal.pbio.0050017

By:

Kannan, Natarajan;
Taylor, Susan S.;
Zhai, Yufeng;
Venter, J. Craig;
Manning, Gerard

Publication type:

Article

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat.

Published in:

2015

By:

Babbitt, Patricia C.;
Bagos, Pantelis G.;
Bairoch, Amos;
Bateman, Alex;
Chatonnet, Arnaud;
Jinan Chen, Mark;
Craik, David J.;
Finn, Robert D.;
Gloriam, David;
Haft, Daniel H.;
Henrissat, Bernard;
Holliday, Gemma L.;
Isberg, Vignir;
Kaas, Quentin;
Landsman, David;
Lenfant, Nicolas;
Manning, Gerard;
Nozomi Nagano;
Srinivasan, Narayanaswamy;
O'Donovan, Claire

Publication type:

Proceeding

From Plk1 to Plk5.

Published in:

Cell Cycle, 2011, v. 10, n. 14, p. 2255, doi. 10.4161/cc.10.14.16494

By:

De Cárcer, Guillermo;
Manning, Gerard;
Malumbres, Marcos

Publication type:

Article

Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer.

Published in:

BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/1471-2164-16-S8-S5

By:

Gnad, Florian;
Doll, Sophia;
Manning, Gerard;
Arnott, David;
Zemin Zhang

Publication type:

Article

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 6, p. 2068, doi. 10.1128/MCB.23.6.2068-2082.2003

By:

Wright, Jocelyn H.;
Xueyan Wang;
Manning, Gerard;
LaMere, Brandon J.;
Phuong Le;
Zhu, Shirley;
Deepak Khatry;
Flanagan, Peter M.;
Buckley, Sharon D.;
Whyte, David B.;
Howlett, Anthony R.;
Bischoff, James R.;
Lipson, Kenneth E.;
Jallal, Bahija

Publication type:

Article

The Capsaspora genome reveals a complex unicellular prehistory of animals.

Published in:

Nature Communications, 2013, v. 4, n. 8, p. 2325, doi. 10.1038/ncomms3325

By:

Suga, Hiroshi;
Chen, Zehua;
de Mendoza, Alex;
Sebé-Pedrós, Arnau;
Brown, Matthew W.;
Kramer, Eric;
Carr, Martin;
Kerner, Pierre;
Vervoort, Michel;
Sánchez-Pons, Núria;
Torruella, Guifré;
Derelle, Romain;
Manning, Gerard;
Lang, B. Franz;
Russ, Carsten;
Haas, Brian J.;
Roger, Andrew J.;
Nusbaum, Chad;
Ruiz-Trillo, Iñaki

Publication type:

Article

Acute Post‐Measles Encephalitis in a Returning Traveller: Highlighting the Need for MMR Vaccination.

Published in:

Reviews in Medical Virology, 2024, v. 34, n. 6, p. 1, doi. 10.1002/rmv.2588

By:

Johnson, Sarah May;
Hassell, Jane;
Manning, Gerard Leslie Peter;
Sudhakar, Sniya;
Brierley, Joe;
Grandjean, Louis;
Breuer, Judith;
Kadambari, Seilesh

Publication type:

Article

Programmed ribosomal frameshifting in the expression of the regulator of intestinal stem cell proliferation, adenomatous polyposis coli (APC).

Published in:

RNA Biology, 2011, v. 8, n. 4, p. 637, doi. 10.4161/rna.8.4.15395

By:

Baranov, Pavel V.;
Wills, Norma M.;
Barriscale, Kathy A.;
Firth, Andrew E.;
Jud, Molly C.;
Letsou, Anthea;
Manning, Gerard;
Atkins, John F.

Publication type:

Article

Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases.

Published in:

Nature Chemical Biology, 2008, v. 4, n. 10, p. 617, doi. 10.1038/nchembio.113

By:

O'Maille, Paul E.;
Malone, Arthur;
Dellas, Nikki;
Andes Hess Jr., B.;
Smentek, Lidia;
Sheehan, Iseult;
Greenhagen, Bryan T.;
Chappell, Joe;
Manning, Gerard;
Noel, Joseph P.

Publication type:

Article

Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta.

Published in:

Genome Biology, 2013, v. 14, n. 2, p. 1, doi. 10.1186/gb-2013-14-2-r15

By:

Fairclough, Stephen R.;
Zehua Chen;
Kramer, Eric;
Zeng, Qiandong;
Young, Sarah;
Robertson, Hugh M.;
Begovic, Emina;
Richter, Daniel J.;
Russ, Carsten;
Westbrook, M. Jody;
Manning, Gerard;
Lang, B. Franz;
Haas, Brian;
Nusbaum, Chad;
King, Nicole

Publication type:

Article

The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology.

Published in:

Genome Biology, 2011, v. 12, n. 7, p. 1, doi. 10.1186/gb-2011-12-7-r66

By:

Manning, Gerard;
Reiner, David S.;
Lauwaet, Tineke;
Dacre, Michael;
Smith, Alias;
Yufeng Zhai;
Svard, Staffan;
Gillin, Frances D.

Publication type:

Article

HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors.

Published in:

2018

By:

Daemen, Anneleen;
Manning, Gerard

Publication type:

journal article

The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors.

Published in:

PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0231999

By:

Rinaldi, Jacob;
Sokol, Ethan S.;
Hartmaier, Ryan J.;
Trabucco, Sally E.;
Frampton, Garrett M.;
Goldberg, Michael E.;
Albacker, Lee A.;
Daemen, Anneleen;
Manning, Gerard

Publication type:

Article

RPN-6 determines C. elegans longevity under proteotoxic stress conditions.

Published in:

Nature, 2012, v. 489, n. 7415, p. 263, doi. 10.1038/nature11315

By:

Vilchez, David;
Morantte, Ianessa;
Liu, Zheng;
Douglas, Peter M.;
Merkwirth, Carsten;
Rodrigues, Ana P. C.;
Manning, Gerard;
Dillin, Andrew

Publication type:

Article

Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.

Published in:

Nature, 2012, v. 485, n. 7399, p. 530, doi. 10.1038/nature11009

By:

Ngaki, Micheline N.;
Louie, Gordon V.;
Philippe, Ryan N.;
Manning, Gerard;
Pojer, Florence;
Bowman, Marianne E.;
Li, Ling;
Larsen, Elise;
Wurtele, Eve Syrkin;
Noel, Joseph P.

Publication type:

Article

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.

Published in:

Nature, 2011, v. 470, n. 7334, p. 404, doi. 10.1038/nature09706

By:

Mair, William;
Morantte, Ianessa;
Rodrigues, Ana P. C.;
Manning, Gerard;
Montminy, Marc;
Shaw, Reuben J.;
Dillin, Andrew

Publication type:

Article

Cyclin-dependent kinases: a family portrait.

Published in:

2009

By:

Malumbres, Marcos;
Harlow, Edward;
Hunt, Tim;
Hunter, Tony;
Lahti, Jill M.;
Manning, Gerard;
Morgan, David O.;
Tsai, Li-Huei;
Wolgemuth, Debra J.

Publication type:

Letter

Key challenges for the creation and maintenance of specialist protein resources.

Published in:

2015

By:

Holliday, Gemma L.;
Bairoch, Amos;
Bagos, Pantelis G.;
Chatonnet, Arnaud;
Craik, David J.;
Finn, Robert D.;
Henrissat, Bernard;
Landsman, David;
Manning, Gerard;
Nagano, Nozomi;
O'Donovan, Claire;
Pruitt, Kim D.;
Rawlings, Neil D.;
Saier, Milton;
Sowdhamini, Ramanathan;
Spedding, Michael;
Srinivasan, Narayanaswamy;
Vriend, Gert;
Babbitt, Patricia C.;
Bateman, Alex

Publication type:

Editorial

Genomics, evolution, and crystal structure of a new family of bacterial spore kinases.

Published in:

Proteins, 2010, v. 78, n. 6, p. 1470, doi. 10.1002/prot.22663

By:

Scheeff, Eric D.;
Axelrod, Herbert L.;
Miller, Mitchell D.;
Chiu, Hsiu-Ju;
Deacon, Ashley M.;
Wilson, Ian A.;
Manning, Gerard

Publication type:

Article

Amphioxus encodes the largest known family of green fluorescent proteins, which have diversified into distinct functional classes.

Published in:

BMC Evolutionary Biology, 2009, v. 9, p. 1, doi. 10.1186/1471-2148-9-77

By:

Bomati, Erin K.;
Manning, Gerard;
Deheyn, Dimitri D.

Publication type:

Article

The Dictyostelium Kinome—Analysis of the<br /> Protein Kinases from a Simple Model Organism.

Published in:

PLoS Genetics, 2006, v. 2, n. 3, p. e38, doi. 10.1371/journal.pgen.0020038

By:

Goldberg, Jonathan M.;
Manning, Gerard;
Liu, Allen;
Fey, Petra;
Pilcher, Karen E.;
Xu, Yanji;
Smith, Janet L.

Publication type:

Article