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How can drug discovery for psychiatric disorders be improved?
- Published in:
- 2007
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- Publication type:
- review
The Role of Hippocampal GluR1 and GluR2 Receptors in Manic-Like Behavior.
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- Journal of Neuroscience, 2008, v. 27, n. 53, p. 68, doi. 10.1523/JNEUROSCI.3080-07.2008
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- Publication type:
- Article
The Anti-Apoptotic, Glucocorticoid Receptor Cochaperone Protein BAG-1 Is a Long-Term Target for the Actions of Mood Stabilizers.
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- Journal of Neuroscience, 2005, v. 25, n. 18, p. 4493, doi. 10.1523/JNEUROSCI.4530-04.2005
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- Publication type:
- Article
Mood Stabilizer Valproate Promotes ERK Pathway-Dependent Cortical Neuronal Growth and Neurogenesis.
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- Journal of Neuroscience, 2004, v. 24, n. 29, p. 6590, doi. 10.1523/JNEUROSCI.5747-03.2004
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- Publication type:
- Article
Modulation of Synaptic Plasticity by Antimanic Agents: The Role of AMPA Glutamate Receptor Subunit 1 Synaptic Expression.
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- Journal of Neuroscience, 2004, v. 24, n. 29, p. 6578, doi. 10.1523/JNEUROSCI.1258-04.2004
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- Publication type:
- Article
Identification of molecular mechanisms underlying mood stabilization through genome-wide gene expression profilingSee Chetcuti et al. (this issue). Altered gene expression in mice treated with the mood stabilizer sodium valproate.
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- International Journal of Neuropsychopharmacology, 2006, v. 9, n. 3, p. 263, doi. 10.1017/s1461145705006176
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- Publication type:
- Article
Focus on CaMKII: a molecular switch in the pathophysiology and treatment of mood and anxiety disorders.
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- International Journal of Neuropsychopharmacology, 2004, v. 7, n. 3, p. 243, doi. 10.1017/S1461145704004432
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- Publication type:
- Article
Strategies for Gene and Protein Expression Studies in Neuropsychopharmacology and Biological Psychiatry.
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- International Journal of Neuropsychopharmacology, 2001, v. 4, n. 1, p. 45, doi. 10.1017/S1461145701009476
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- Publication type:
- Article
Signalling pathways in the brain: Cellular transduction of mood stabilisation in the treatment of manic-depressive illness.
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- Australian & New Zealand Journal of Psychiatry, 1999, v. 33, p. S65, doi. 10.1111/j.1440-1614.1999.00670.x
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- Publication type:
- Article
Early intervention in bipolar disorder, part I: clinical and imaging findings.
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- Early Intervention in Psychiatry, 2008, v. 2, n. 3, p. 122, doi. 10.1111/j.1751-7893.2008.00071.x
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- Publication type:
- Article
Early intervention in bipolar disorder, part II: therapeutics.
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- Early Intervention in Psychiatry, 2008, v. 2, n. 3, p. 136, doi. 10.1111/j.1751-7893.2008.00072.x
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- Publication type:
- Article
Long-term action of lithium: A role for transcriptional and posttranscriptional factors regulated by protein kinase C.
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- Synapse, 1994, v. 16, n. 1, p. 11, doi. 10.1002/syn.890160103
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- Publication type:
- Article
Evidence for Involvement of ERK, PI3K, and RSK in Induction of Bcl-2 by Valproate.
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- Journal of Molecular Neuroscience, 2009, v. 37, n. 2, p. 123, doi. 10.1007/s12031-008-9122-2
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- Publication type:
- Article
Neuronal Peroxisome Proliferator-Activated Receptor γ Signaling: Regulation by Mood-Stabilizer Valproate.
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- Journal of Molecular Neuroscience, 2008, v. 35, n. 2, p. 225, doi. 10.1007/s12031-008-9056-8
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- Publication type:
- Article
New insights into BDNF function in depression and anxiety.
- Published in:
- Nature Neuroscience, 2007, v. 10, n. 9, p. 1089, doi. 10.1038/nn1971
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- Publication type:
- Article
Genome-wide gene expression profiling in GluR1 knockout mice: key role of the calcium signaling pathway in glutamatergically mediated hippocampal transmission.
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- European Journal of Neuroscience, 2009, v. 30, n. 12, p. 2318, doi. 10.1111/j.1460-9568.2009.07022.x
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- Publication type:
- Article
MicroRNAs in Mental Health: From Biological Underpinnings to Potential Therapies.
- Published in:
- NeuroMolecular Medicine, 2009, v. 11, n. 3, p. 173, doi. 10.1007/s12017-009-8070-5
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- Publication type:
- Article
Platelet α2-adrenoreceptors in depression: a critical examination.
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- Journal of Psychopharmacology, 1993, v. 7, p. 4, doi. 10.1177/0269881193007001031
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- Publication type:
- Article
ECT treatment does not enhance neuroendocrine responses to serotonergic challenge.
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- Journal of Psychopharmacology, 1992, v. 6, n. 4, p. 501, doi. 10.1177/026988119200600405
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- Publication type:
- Article
Bag-1 mediates glucocorticoid receptor trafficking to mitochondria after corticosterone stimulation: Potential role in regulating affective resilience.
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- Journal of Neurochemistry, 2021, v. 158, n. 2, p. 358, doi. 10.1111/jnc.15211
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- Publication type:
- Article
Bag‐1 mediates glucocorticoid receptor trafficking to mitochondria after corticosterone stimulation: Potential role in regulating affective resilience.
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- Journal of Neurochemistry, 2021, v. 158, n. 1, p. 358, doi. 10.1111/jnc.15211
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- Publication type:
- Article
Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study.
- Published in:
- Neuropsychopharmacology, 2012, v. 37, n. 6, p. 1526, doi. 10.1038/npp.2011.338
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- Publication type:
- Article
Serotonin Depletion Hampers Survival and Proliferation in Neurospheres Derived from Adult Neural Stem Cells.
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- Neuropsychopharmacology, 2010, v. 35, n. 4, p. 893, doi. 10.1038/npp.2009.181
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- Publication type:
- Article
Evidence for Selective microRNAs and Their Effectors as Common Long-Term Targets for the Actions of Mood Stabilizers.
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- Neuropsychopharmacology, 2009, v. 34, n. 6, p. 1395, doi. 10.1038/npp.2008.131
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- Publication type:
- Article
Non-canonical pathways in the pathophysiology and therapeutics of bipolar disorder.
- Published in:
- Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1228455
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- Publication type:
- Article
Lithium Activates the c-Jun NH<sub>2</sub>-Terminal Kinases In Vitro and in the CNS In Vivo.
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- Journal of Neurochemistry, 1999, v. 73, n. 6, p. 2299, doi. 10.1046/j.1471-4159.1999.0732299.x
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- Publication type:
- Article
Lithium Increases Tyrosine Hydroxylase Levels Both In Vivo and In Vitro.
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- Journal of Neurochemistry, 1998, v. 70, n. 4, p. 1768, doi. 10.1046/j.1471-4159.1998.70041768.x
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- Publication type:
- Article
A Naturally Occurring Amino Acid Substitution of the Human Serotonin 5-HT<sub>2A</sub> Receptor Influences Amplitude and Timing of Intracellular Calcium Mobilization.
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- Journal of Neurochemistry, 1997, v. 68, n. 5, p. 2186, doi. 10.1046/j.1471-4159.1997.68052186.x
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- Publication type:
- Article
Attenuation of Cyclic AMP Production by Carbamazepine.
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- Journal of Neurochemistry, 1996, v. 67, n. 5, p. 2079, doi. 10.1046/j.1471-4159.1996.67052079.x
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- Publication type:
- Article
Chronic Sodium Valproate Selectively Decreases Protein Kinase C α and ε In Vitro.
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- Journal of Neurochemistry, 1994, v. 63, n. 6, p. 2361, doi. 10.1046/j.1471-4159.1994.63062361.x
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- Publication type:
- Article
In Vivo Evidence that Nonneuronal β-Adrenoceptors as Well as Dopamine Receptors Contribute to Cyclic AMP Efflux in Rat Striatum.
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- Journal of Neurochemistry, 1994, v. 62, n. 5, p. 1734, doi. 10.1046/j.1471-4159.1994.62051734.x
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- Publication type:
- Article
Lithium Decreases Membrane-Associated Protein Kinase C in Hippocampus: Selectivity for the α Isozyme.
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- Journal of Neurochemistry, 1993, v. 61, n. 6, p. 2303, doi. 10.1111/j.1471-4159.1993.tb07474.x
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- Publication type:
- Article
Structurally Dissimilar Antimanic Agents Modulate Synaptic Plasticity by Regulating AMPA Glutamate Receptor Subunit GluR1 Synaptic Expression.
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- Annals of the New York Academy of Sciences, 2003, v. 1003, n. 1, p. 378, doi. 10.1196/annals.1300.031
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- Publication type:
- Article
Lithium Regulates Total and Synaptic Expression of the AMPA Glutamate Receptor GluR2 in Vitro and in Vivo.
- Published in:
- Annals of the New York Academy of Sciences, 2003, v. 1003, n. 1, p. 402, doi. 10.1196/annals.1300.036
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- Publication type:
- Article
Regulation of Cellular Plasticity Cascades in the Pathophysiology and Treatment of Mood Disorders.
- Published in:
- Annals of the New York Academy of Sciences, 2003, v. 1003, n. 1, p. 273, doi. 10.1196/annals.1300.017
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- Publication type:
- Article
Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression: A Randomized Clinical Trial.
- Published in:
- 2018
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- Publication type:
- journal article
Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions.
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- Metabolomics, 2010, v. 6, n. 2, p. 165, doi. 10.1007/s11306-010-0208-9
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- Publication type:
- Article
New Approaches to Modeling Bipolar Disorder.
- Published in:
- Psychopharmacology Bulletin, 2003, v. 37, n. 1, p. 47
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- Publication type:
- Article
Modulators of the Glutamatergic System: Implications for the Development of Improved Therapeutics in Mood Disorders.
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- Psychopharmacology Bulletin, 2002, v. 36, n. 4, p. 35
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- Publication type:
- Article
Lithium Salts in AIDS and AIDS-Related Dementia.
- Published in:
- Psychopharmacology Bulletin, 2002, v. 36, n. 1, p. 5
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- Publication type:
- Article
Impairments of Neuroplasticity and Cellular Resilience in Severe Mood Disorders: Implications for the Development of Novel Therapeutics.
- Published in:
- Psychopharmacology Bulletin, 2001, v. 35, n. 2, p. 5
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- Publication type:
- Article
Alterations in Cyclic AMP Generation and G Protein Subunits Following Transient Ischemia inGerbil Hippocampus.
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- Journal of Cerebral Blood Flow & Metabolism, 1995, v. 15, n. 5, p. 877, doi. 10.1038/jcbfm.1995.109
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- Publication type:
- Article
Harnessing digital technology to predict, diagnose, monitor, and develop treatments for brain disorders.
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- NPJ Digital Medicine, 2019, v. 2, p. N.PAG, doi. 10.1038/s41746-019-0123-z
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- Publication type:
- Article
Getting balance: Drugs for bipolar disorder share target.
- Published in:
- Nature Medicine, 2002, v. 8, n. 6, p. 557, doi. 10.1038/nm0602-557
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- Publication type:
- Article
The cellular neurobiology of depression.
- Published in:
- Nature Medicine, 2001, v. 7, n. 5, p. 541, doi. 10.1038/87865
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- Publication type:
- Article
Arc Regulates Experience-Dependent Persistent Firing Patterns in Frontal Cortex.
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- Journal of Neuroscience, 2014, v. 34, n. 19, p. 6583, doi. 10.1523/JNEUROSCI.0167-14.2014
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- Publication type:
- Article
Impaired mitochondrial function in psychiatric disorders.
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- Nature Reviews Neuroscience, 2012, v. 13, n. 5, p. 293, doi. 10.1038/nrn3229
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- Publication type:
- Article
The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders.
- Published in:
- Neuroscientist, 2009, v. 15, n. 5, p. 525, doi. 10.1177/1073858409336093
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- Publication type:
- Article
The Wnt Signaling Pathway in Bipolar Disorder.
- Published in:
- Neuroscientist, 2002, v. 8, n. 5, p. 497, doi. 10.1177/107385802237176
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- Publication type:
- Article
Differential effect of lithium on cell number in the hippocampus and prefrontal cortex in adult mice: a stereological study.
- Published in:
- Bipolar Disorders, 2016, v. 18, n. 1, p. 41, doi. 10.1111/bdi.12364
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- Publication type:
- Article