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Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond.
Published in:
Seminars in Immunopathology, 2019, v. 41, n. 1, p. 41, doi. 10.1007/s00281-018-0702-0
By:
- Muller, Alexander J.;
- Manfredi, Mark G.;
- Zakharia, Yousef;
- Prendergast, George C.
Publication type:
Article
Multimodal Imaging with <sup>18</sup>F-FDG PET and Cerenkov Luminescence Imaging After MLN4924 Treatment in a Human Lymphoma Xenograft Model.
Published in:
Journal of Nuclear Medicine, 2011, v. 52, n. 11, p. 1764, doi. 10.2967/jnumed.111.091710
By:
- Robertson, Robbie;
- Germanos, Melissa Saylor;
- Manfredi, Mark G.;
- Smith, Peter G.;
- Silva, Matthew D.
Publication type:
Article
Preclinical pharmacokinetic/pharmacodynamic/efficacy relationships for alisertib, an investigational small-molecule inhibitor of Aurora A kinase.
Published in:
Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 6, p. 1255, doi. 10.1007/s00280-013-2305-8
By:
- Palani, Santhosh;
- Patel, Mayankbhai;
- Huck, Jessica;
- Zhang, Mengkun;
- Balani, Suresh K.;
- Yang, Johnny;
- Chen, Susan;
- Mettetal, Jerome;
- Manfredi, Mark;
- Shyu, Wen Chyi;
- Ecsedy, Jeffrey A.;
- Chakravarty, Arijit
Publication type:
Article
Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1145, doi. 10.1007/s00280-011-1591-2
By:
- Bannerman, Bret;
- Xu, Ling;
- Jones, Matthew;
- Tsu, Christopher;
- Yu, Jie;
- Hales, Paul;
- Monbaliu, Johan;
- Fleming, Paul;
- Dick, Lawrence;
- Manfredi, Mark;
- Claiborne, Christopher;
- Bolen, Joseph;
- Kupperman, Erik;
- Berger, Allison
Publication type:
Article
Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1291, doi. 10.1007/s00280-011-1618-8
By:
- Carol, Hernan;
- Boehm, Ingrid;
- Reynolds, C.;
- Kang, Min;
- Maris, John;
- Morton, Christopher;
- Gorlick, Richard;
- Kolb, E.;
- Keir, Stephen;
- Wu, Jianrong;
- Wozniak, Amy;
- Yang, Yu;
- Manfredi, Mark;
- Ecsedy, Jeffrey;
- Wang, Jianmin;
- Neale, Geoffrey;
- Houghton, Peter;
- Smith, Malcolm;
- Lock, Richard
Publication type:
Article
Phase 1 study of MLN8054, a selective inhibitor of Aurora A kinase in patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 4, p. 945, doi. 10.1007/s00280-010-1377-y
By:
- Dees, E.;
- Infante, Jeffrey;
- Cohen, Roger;
- O'Neil, Bert;
- Jones, Suzanne;
- Mehren, Margaret;
- Danaee, Hadi;
- Lee, Yih;
- Ecsedy, Jeffrey;
- Manfredi, Mark;
- Galvin, Katherine;
- Stringer, Bradley;
- Liu, Hua;
- Eton, Omar;
- Fingert, Howard;
- Burris, Howard
Publication type:
Article
KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.
Published in:
PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0144825
By:
- Chattopadhyay, Nibedita;
- Berger, Allison J.;
- Koenig, Erik;
- Bannerman, Bret;
- Garnsey, James;
- Bernard, Hugues;
- Hales, Paul;
- Maldonado Lopez, Angel;
- Yang, Yu;
- Donelan, Jill;
- Jordan, Kristen;
- Tirrell, Stephen;
- Stringer, Bradley;
- Xia, Cindy;
- Hather, Greg;
- Galvin, Katherine;
- Manfredi, Mark;
- Rhodes, Nelson;
- Amidon, Ben
Publication type:
Article
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20223-y
By:
- Tajan, Mylène;
- Hennequart, Marc;
- Cheung, Eric C.;
- Zani, Fabio;
- Hock, Andreas K.;
- Legrave, Nathalie;
- Maddocks, Oliver D. K.;
- Ridgway, Rachel A.;
- Athineos, Dimitris;
- Suárez-Bonnet, Alejandro;
- Ludwig, Robert L.;
- Novellasdemunt, Laura;
- Angelis, Nikolaos;
- Li, Vivian S. W.;
- Vlachogiannis, Georgios;
- Valeri, Nicola;
- Mainolfi, Nello;
- Suri, Vipin;
- Friedman, Adam;
- Manfredi, Mark
Publication type:
Article
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17750-z
By:
- Campesato, Luis Felipe;
- Budhu, Sadna;
- Tchaicha, Jeremy;
- Weng, Chien-Huan;
- Gigoux, Mathieu;
- Cohen, Ivan Jose;
- Redmond, David;
- Mangarin, Levi;
- Pourpe, Stephane;
- Liu, Cailian;
- Zappasodi, Roberta;
- Zamarin, Dmitriy;
- Cavanaugh, Jill;
- Castro, Alfredo C.;
- Manfredi, Mark G.;
- McGovern, Karen;
- Merghoub, Taha;
- Wolchok, Jedd D.
Publication type:
Article
A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191046
By:
- Gallery, Melissa;
- Zhang, Julie;
- Bradley, Daniel P.;
- Brauer, Pamela;
- Cvet, Donna;
- Estevam, Jose;
- Danaee, Hadi;
- Greenfield, Edward;
- Li, Ping;
- Manfredi, Mark;
- Loke, Huay-Keng;
- Rabino, Claudia;
- Stringer, Brad;
- Williamson, Mark;
- Wyant, Tim;
- Yang, Johnny;
- Zhu, Qing;
- Abu-Yousif, Adnan;
- Veiby, O. Petter
Publication type:
Article

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