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Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells.
- Published in:
- Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1359147
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- Publication type:
- Article
Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14585, doi. 10.3390/ijms241914585
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- Publication type:
- Article
Obesity‐induced changes in gene expression in feline adipose and skeletal muscle tissue.
- Published in:
- Journal of Animal Physiology & Animal Nutrition, 2023, v. 107, n. 5, p. 1262, doi. 10.1111/jpn.13802
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- Publication type:
- Article
Interaction Between Dietary Iron Intake and Genetically Determined Iron Overload: Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in the TEDDY Study.
- Published in:
- Diabetes Care, 2023, v. 46, n. 5, p. 1014, doi. 10.2337/dc22-1359
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- Publication type:
- Article
A randomized, double‐blind, crossover study of the effect of the fluoroquinolone moxifloxacin on glucose levels and insulin sensitivity in young men and women.
- Published in:
- Diabetes, Obesity & Metabolism, 2023, v. 25, n. 1, p. 98, doi. 10.1111/dom.14851
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- Publication type:
- Article
A Blunted GPR183/Oxysterol Axis During Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung During Mycobacterium tuberculosis Infection.
- Published in:
- 2022
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- Publication type:
- journal article
Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells.
- Published in:
- Biomedicines, 2022, v. 10, n. 4, p. 814, doi. 10.3390/biomedicines10040814
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- Publication type:
- Article
Celebrities in the heart, strangers in the pancreatic beta cell: Voltage‐gated potassium channels K<sub>v</sub>7.1 and K<sub>v</sub>11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes.
- Published in:
- Acta Physiologica, 2022, v. 234, n. 3, p. 1, doi. 10.1111/apha.13781
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- Publication type:
- Article
Divalent Metal Transporter 1 Knock-Down Modulates IL-1β Mediated Pancreatic Beta-Cell Pro-Apoptotic Signaling Pathways through the Autophagic Machinery.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8013, doi. 10.3390/ijms22158013
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- Publication type:
- Article
Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90452-8
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- Article
Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk.
- Published in:
- Diabetologia, 2021, v. 64, n. 4, p. 826, doi. 10.1007/s00125-020-05358-3
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- Publication type:
- Article
Proinflammatory Cytokines Perturb Mouse and Human Pancreatic Islet Circadian Rhythmicity and Induce Uncoordinated β-Cell Clock Gene Expression via Nitric Oxide, Lysine Deacetylases, and Immunoproteasomal Activity.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 83, doi. 10.3390/ijms22010083
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- Publication type:
- Article
GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity.
- Published in:
- Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.601534
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- Publication type:
- Article
Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in β-Cells.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8016, doi. 10.3390/ijms21218016
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- Publication type:
- Article
Pancreatic β-cells respond to fuel pressure with an early metabolic switch.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72348-1
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- Publication type:
- Article
Interleukin-6 receptor blockade or TNFα inhibition for reducing glycaemia in patients with RA and diabetes: post hoc analyses of three randomised, controlled trials.
- Published in:
- Arthritis Research & Therapy, 2020, v. 22, n. 1, p. 1, doi. 10.1186/s13075-020-02229-5
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- Publication type:
- Article
The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4311, doi. 10.3390/ijms21124311
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- Publication type:
- Article
Combination of ferric ammonium citrate with cytokines involved in apoptosis and insulin secretion of human pancreatic beta cells related to diabetes in thalassemia.
- Published in:
- PeerJ, 2020, p. 1, doi. 10.7717/peerj.9298
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- Publication type:
- Article
The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β.
- Published in:
- PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0222432
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- Publication type:
- Article
The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis.
- Published in:
- Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/5451038
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- Publication type:
- Article
Treatment of type 2 diabetes by targeting interleukin-1: a meta-analysis of 2921 patients.
- Published in:
- Seminars in Immunopathology, 2019, v. 41, n. 4, p. 413, doi. 10.1007/s00281-019-00743-6
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- Publication type:
- Article
No direct effect of SGLT2 activity on glucagon secretion.
- Published in:
- Diabetologia, 2019, v. 62, n. 6, p. 1011, doi. 10.1007/s00125-019-4849-6
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- Publication type:
- Article
054 Effect of sarilumab on glycosylated hemoglobin in patients with rheumatoid arthritis and diabetes.
- Published in:
- 2019
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- Publication type:
- Abstract
Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.
- Published in:
- 2019
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- Publication type:
- journal article
The No-Go and Nonsense-Mediated RNA Decay Pathways Are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and Survival.
- Published in:
- 2018
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- Publication type:
- journal article
MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage.
- Published in:
- PLoS ONE, 2018, v. 13, n. 9, p. 1, doi. 10.1371/journal.pone.0203713
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- Publication type:
- Article
Iron Status and Gestational Diabetes—A Meta-Analysis.
- Published in:
- Nutrients, 2018, v. 10, n. 5, p. 621, doi. 10.3390/nu10050621
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- Publication type:
- Article
Increased Plasma Ferritin Concentration and Low-Grade Inflammation--A Mendelian Randomization Study.
- Published in:
- Clinical Chemistry, 2018, v. 64, n. 2, p. 374, doi. 10.1373/clinchem.2017.276055
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- Publication type:
- Article
Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice.
- Published in:
- Diabetologia, 2018, v. 61, n. 2, p. 389, doi. 10.1007/s00125-017-4459-0
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- Article
Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No.
- Published in:
- 2017
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- Publication type:
- journal article
Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study.
- Published in:
- 2017
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- Publication type:
- journal article
Regional differences in milk and complementary feeding patterns in infants participating in an international nutritional type 1 diabetes prevention trial.
- Published in:
- Maternal & Child Nutrition, 2017, v. 13, n. 3, p. n/a, doi. 10.1111/mcn.12354
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- Publication type:
- Article
A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells.
- Published in:
- International Journal of Molecular Sciences, 2016, v. 17, n. 6, p. 896, doi. 10.3390/ijms17060896
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- Publication type:
- Article
A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats.
- Published in:
- PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0154727
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- Publication type:
- Article
MicroRNAs as regulators of beta-cell function and dysfunction.
- Published in:
- 2016
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- Publication type:
- journal article
Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset.
- Published in:
- European Journal of Immunology, 2016, v. 46, n. 4, p. 1030, doi. 10.1002/eji.201546005
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- Publication type:
- Article
JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression.
- Published in:
- Disease Markers, 2016, p. 1, doi. 10.1155/2016/1312705
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- Publication type:
- Article
JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression.
- Published in:
- Journal of Diabetes Research, 2016, p. 1, doi. 10.1155/2016/1312705
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- Publication type:
- Article
Skeletal Muscle to Pancreatic β-Cell Cross-talk: The Effect of Humoral Mediators Liberated by Muscle Contraction and Acute Exercise on β-Cell Apoptosis.
- Published in:
- 2015
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- Publication type:
- journal article
Tissue Inhibitor Of Matrix Metalloproteinase-1 Is Required for High-Fat Diet-Induced Glucose Intolerance and Hepatic Steatosis in Mice.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132910
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- Publication type:
- Article
Inhibition of beta cell growth and function by bone morphogenetic proteins.
- Published in:
- Diabetologia, 2014, v. 57, n. 12, p. 2546, doi. 10.1007/s00125-014-3384-8
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- Publication type:
- Article
Interleukin-1 Antagonism: A Sturdy Companion for Immune Tolerance Induction in Type 1 Diabetes?
- Published in:
- Diabetes, 2014, v. 63, n. 6, p. 1833, doi. 10.2337/db14-0371
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- Publication type:
- Article
Need for Reclassification of Diabetes Secondary to Iron Overload in the ADA and WHO Classifications.
- Published in:
- Diabetes Care, 2014, v. 37, n. 6, p. e137, doi. 10.2337/dc14-0119
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- Publication type:
- Article
Use of vitamin D supplements during infancy in an international feeding trial.
- Published in:
- Public Health Nutrition, 2014, v. 17, n. 4, p. 810, doi. 10.1017/S1368980013001122
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- Publication type:
- Article
Total and Cause-Specific Mortality by Elevated Transferrin Saturation and Hemochromatosis Genotype in Individuals With Diabetes: Two General Population Studies.
- Published in:
- Diabetes Care, 2014, v. 37, n. 2, p. 444, doi. 10.2337/dc13-1198
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- Publication type:
- Article
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist.
- Published in:
- Journal of Neuroinflammation, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1742-2094-11-27
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- Publication type:
- Article
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist.
- Published in:
- 2014
- By:
- Publication type:
- journal article
JNK1 Protects against Glucolipotoxicity-Mediated Beta-Cell Apoptosis.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087067
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- Publication type:
- Article
Total Mortality by Elevated Transferrin Saturation in Patients With Diabetes.
- Published in:
- Diabetes Care, 2013, v. 36, n. 9, p. 2646, doi. 10.2337/dc12-2032
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- Publication type:
- Article
Serum adipokines as biomarkers of beta-cell function in patients with type 1 diabetes: positive association with leptin and resistin and negative association with adiponectin.
- Published in:
- Diabetes/Metabolism Research & Reviews, 2013, v. 29, n. 2, p. 166, doi. 10.1002/dmrr.2378
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- Publication type:
- Article