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Apoptosis and the pathogenesis of IDDM: a question of life and death.
- Published in:
- 1998
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- Publication type:
- journal article
Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission.
- Published in:
- 2007
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- Publication type:
- Journal Article
Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission.
- Published in:
- Diabetic Medicine, 2007, v. 24, n. 5, p. 512, doi. 10.1111/j.1464-5491.2007.02096.x
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- Publication type:
- Article
Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats.
- Published in:
- Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 703, doi. 10.1111/dom.12470
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- Publication type:
- Article
Age-dependent decline of β-cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study.
- Published in:
- Diabetes, Obesity & Metabolism, 2014, v. 16, n. 3, p. 262, doi. 10.1111/dom.12216
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- Publication type:
- Article
Small-molecule inhibition of inflammatory β-cell death.
- Published in:
- Diabetes, Obesity & Metabolism, 2013, v. 15, p. 176, doi. 10.1111/dom.12158
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- Publication type:
- Article
Functional SOCS1 polymorphisms are associated with variation in obesity in whites.
- Published in:
- Diabetes, Obesity & Metabolism, 2009, v. 11, n. 3, p. 196, doi. 10.1111/j.1463-1326.2008.00900.x
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- Publication type:
- Article
The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase.
- Published in:
- Cellular & Molecular Life Sciences, 2008, v. 65, n. 7/8, p. 1248, doi. 10.1007/s00018-008-7564-x
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- Publication type:
- Article
The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.
- Published in:
- 2000
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- Publication type:
- journal article
Beta-cell maturation leads to in vitro sensitivity to cytotoxins.
- Published in:
- 1999
- By:
- Publication type:
- journal article
Ciliary neurotrophic factor potentiates the beta-cell inhibitory effect of IL-1beta in rat pancreatic islets associated with increased nitric oxide synthesis and increased expression of inducible nitric oxide synthase.
- Published in:
- 1998
- By:
- Publication type:
- journal article
Linkage and association between a CD4 gene polymorphism and IDDM in Danish IDDM patients. The Danish IDDM Epidemiology and Genetics Group, and The Danish Study Group of Diabetes in Childhood.
- Published in:
- 1998
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- Publication type:
- journal article
Strain-dependent differences in sensitivity of rat beta-cells to interleukin 1 beta in vitro and in vivo: association with islet nitric oxide synthesis.
- Published in:
- 1996
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- Publication type:
- journal article
Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide.
- Published in:
- 1995
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- Publication type:
- journal article
Glutamic acid decarboxylase (GAD65) autoantibodies in prediction of beta-cell function and remission in recent-onset IDDM after cyclosporin treatment. The Canadian-European Randomized Control Trial Group.
- Published in:
- 1994
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- Publication type:
- journal article
Monokine antagonism is reduced in patients with IDDM.
- Published in:
- 1994
- By:
- Publication type:
- journal article
Nicotinamide prevents interleukin-1 effects on accumulated insulin release and nitric oxide production in rat islets of Langerhans.
- Published in:
- 1994
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- Publication type:
- journal article
Lack of predictive value of islet cell antibodies, insulin antibodies, and HLA-DR phenotype for remission in cyclosporin-treated IDDM patients. The Canadian-European Randomized Control Trial Group.
- Published in:
- 1990
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- Publication type:
- journal article
Interaction of beta-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans.
- Published in:
- 1989
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- Publication type:
- journal article
Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics.
- Published in:
- 1987
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- Publication type:
- journal article
Direct effects of cyclosporin A on human pancreatic beta-cells.
- Published in:
- 1986
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- Publication type:
- journal article
Direct Effects of Cyclosporin A on Human Pancreatic β-cells.
- Published in:
- Diabetes, 1986, v. 35, n. 9, p. 1049, doi. 10.2337/diab.35.9.1049
- By:
- Publication type:
- Article
Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance.
- Published in:
- Genes & Immunity, 2006, v. 7, n. 4, p. 316, doi. 10.1038/sj.gene.6364300
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- Publication type:
- Article
Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia.
- Published in:
- Genes & Immunity, 2005, v. 6, n. 8, p. 699, doi. 10.1038/sj.gene.6364259
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- Publication type:
- Article
Characterization of new polymorphisms in the 5′UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level.
- Published in:
- Genes & Immunity, 2000, v. 1, n. 8, p. 495
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- Publication type:
- Article
Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation.
- Published in:
- 2012
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- Publication type:
- journal article
Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Islet Cell Cytoplasmic Antibodies (ICA) in Diabetes and Disorders of Glucose Tolerance.
- Published in:
- Diabetic Medicine, 1991, v. 8, n. 9, p. 812, doi. 10.1111/j.1464-5491.1991.tb02118.x
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- Publication type:
- Article
Nephrotoxicity of Cyclosporin A in Patients with Newly Diagnosed Type 1 Diabetes Mellitus.
- Published in:
- Diabetic Medicine, 1990, v. 7, n. 5, p. 429, doi. 10.1111/j.1464-5491.1990.tb01418.x
- By:
- Publication type:
- Article
A Role for Cyclosporin A in the Treatment of Insulin-dependent Diabetes Mellitus?
- Published in:
- Diabetic Medicine, 1985, v. 2, n. 6, p. 441, doi. 10.1111/j.1464-5491.1985.tb00679.x
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- Publication type:
- Article
BMI is an important driver of β-cell loss in type 1 diabetes upon diagnosis in 10 to 18-year-old children.
- Published in:
- European Journal of Endocrinology, 2015, v. 172, n. 2, p. 107, doi. 10.1530/EJE-14-0522
- By:
- Publication type:
- Article
Dietary Supplementation with ω-3-Polyunsaturated Fatty Acids Decreases Mononuclear Cell Proliferation and Interleukin-1β Content but not Monokine Secretion in Healthy and Insulin--Dependent Diabetic Individuals.
- Published in:
- Scandinavian Journal of Immunology, 1991, v. 34, n. 4, p. 399
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- Publication type:
- Article
Monocyte Function in IDDM Patients and Healthy Individuals.
- Published in:
- Scandinavian Journal of Immunology, 1990, v. 32, n. 3, p. 297, doi. 10.1111/j.1365-3083.1990.tb02924.x
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- Publication type:
- Article
Identification of a Type 1 Diabetes-Associated CD4 Promoter Haplotype with High Constitutive Activity.
- Published in:
- Scandinavian Journal of Immunology, 2004, v. 59, n. 6, p. 582, doi. 10.1111/j.1365-3083.2004.01444.x
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- Publication type:
- Article
Seven years of remission in a type I diabetic patient.
- Published in:
- 1993
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- Publication type:
- journal article
Natural course of remission in IDDM during 1st yr after diagnosis.
- Published in:
- 1992
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- Publication type:
- journal article
The intercellular adhesion molecule-1 K469E polymorphism in type 1 diabetes.
- Published in:
- Immunogenetics, 2000, v. 52, n. 1/2, p. 107, doi. 10.1007/s002510000258
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- Publication type:
- Article
Immune markers for monitoring the progression of autoimmune disease.
- Published in:
- 1999
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- Publication type:
- journal article
Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer term type 1 diabetes.
- Published in:
- Diabetologia, 2013, v. 56, n. 6, p. 1356, doi. 10.1007/s00125-013-2883-3
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- Publication type:
- Article
Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children.
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- Diabetologia, 2012, v. 55, n. 9, p. 2421, doi. 10.1007/s00125-012-2615-0
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- Publication type:
- Article
Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines.
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- Diabetologia, 2010, v. 53, n. 12, p. 2569, doi. 10.1007/s00125-010-1892-8
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- Publication type:
- Article
Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes.
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- Diabetologia, 2010, v. 53, n. 10, p. 2129, doi. 10.1007/s00125-010-1843-4
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- Publication type:
- Article
The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation.
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- Diabetologia, 2010, v. 53, n. 1, p. 10, doi. 10.1007/s00125-009-1573-7
- By:
- Publication type:
- Article
IL-1β-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells.
- Published in:
- Diabetologia, 2009, v. 52, n. 2, p. 281, doi. 10.1007/s00125-008-1199-1
- By:
- Publication type:
- Article
Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection.
- Published in:
- Diabetologia, 2008, v. 51, n. 10, p. 1873, doi. 10.1007/s00125-008-1090-0
- By:
- Publication type:
- Article
Proliferation of sorted human and rat beta cells.
- Published in:
- Diabetologia, 2008, v. 51, n. 1, p. 91, doi. 10.1007/s00125-007-0855-1
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- Publication type:
- Article
Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells.
- Published in:
- Diabetologia, 2007, v. 50, n. 4, p. 779, doi. 10.1007/s00125-006-0562-3
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- Publication type:
- Article
IL-1β-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line.
- Published in:
- Diabetologia, 2006, v. 49, n. 8, p. 1864, doi. 10.1007/s00125-006-0296-2
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- Publication type:
- Article
Growth arrest- and DNA-damage-inducible 45β gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1β-induced apoptosis in insulin-producing INS-1E cells.
- Published in:
- Diabetologia, 2006, v. 49, n. 5, p. 980, doi. 10.1007/s00125-006-0164-0
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- Publication type:
- Article
Plasma cytokine levels in young and elderly twins: genes versus environment and relation to in vivo insulin action.
- Published in:
- Diabetologia, 2006, v. 49, n. 2, p. 343, doi. 10.1007/s00125-005-0080-8
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- Publication type:
- Article