Works by Manahan-Vaughan, Denise

Results: 125

The Suprapyramidal and Infrapyramidal Blades of the Dentate Gyrus Exhibit Different GluN Subunit Content and Dissimilar Frequency‐Dependent Synaptic Plasticity In Vivo.

Published in:

Hippocampus, 2025, v. 35, n. 2, p. 1, doi. 10.1002/hipo.70002

By:

Strauch, Christina;
Böge, Juliane;
Shchyglo, Olena;
Dubovyk, Valentyna;
Manahan‐Vaughan, Denise

Publication type:

Article

Cover Image, Volume 35, Issue 2.

Published in:

Hippocampus, 2025, v. 35, n. 2, p. C1, doi. 10.1002/hipo.70009

By:

Strauch, Christina;
Böge, Juliane;
Shchyglo, Olena;
Dubovyk, Valentyna;
Manahan‐Vaughan, Denise

Publication type:

Article

The Modulation by the Locus Coeruleus of Recent and Remote Memory Retrieval is Activity‐Dependent.

Published in:

Hippocampus, 2025, v. 35, n. 2, p. 1, doi. 10.1002/hipo.70004

By:

Babushkina, Natalia;
Manahan‐Vaughan, Denise

Publication type:

Article

Learning shifts the preferred theta phase of gamma oscillations in CA1.

Published in:

Hippocampus, 2022, v. 32, n. 9, p. 695, doi. 10.1002/hipo.23460

By:

Rayan, Abdelrahman;
Donoso, José R.;
Mendez‐Couz, Marta;
Dolón, Laura;
Cheng, Sen;
Manahan‐Vaughan, Denise

Publication type:

Article

Frequency–dependency of the involvement of dopamine D1/D5 and beta‐adrenergic receptors in hippocampal LTD triggered by locus coeruleus stimulation.

Published in:

Hippocampus, 2022, v. 32, n. 6, p. 449, doi. 10.1002/hipo.23419

By:

Babushkina, Natalia;
Manahan‐Vaughan, Denise

Publication type:

Article

Cover Image, Volume 31, Issue 9.

Published in:

Hippocampus, 2021, v. 31, n. 9, p. C1, doi. 10.1002/hipo.23384

By:

Collitti‐Klausnitzer, Jens;
Hagena, Hardy;
Dubovyk, Valentyna;
Manahan‐Vaughan, Denise

Publication type:

Article

Preferential frequency‐dependent induction of synaptic depression by the lateral perforant path and of synaptic potentiation by the medial perforant path inputs to the dentate gyrus.

Published in:

Hippocampus, 2021, v. 31, n. 9, p. 957, doi. 10.1002/hipo.23338

By:

Collitti‐Klausnitzer, Jens;
Hagena, Hardy;
Dubovyk, Valentyna;
Manahan‐Vaughan, Denise

Publication type:

Article

Hippocampal subfield‐specific Homer1a expression is triggered by learning‐facilitated long‐term potentiation and long‐term depression at medial perforant path synapses.

Published in:

Hippocampus, 2021, v. 31, n. 8, p. 897, doi. 10.1002/hipo.23333

By:

Hoang, Thu‐Huong;
Böge, Juliane;
Manahan‐Vaughan, Denise

Publication type:

Article

Cover Image, Volume 28, Issue 5.

Published in:

Hippocampus, 2018, v. 28, n. 5, p. C1, doi. 10.1002/hipo.22848

By:

Hoang, Thu‐Huong;
Aliane, Verena;
Manahan‐Vaughan, Denise

Publication type:

Article

Novel encoding and updating of positional, or directional, spatial cues are processed by distinct hippocampal subfields: Evidence for parallel information processing and the “what” stream.

Published in:

Hippocampus, 2018, v. 28, n. 5, p. 315, doi. 10.1002/hipo.22833

By:

Hoang, Thu‐Huong;
Aliane, Verena;
Manahan‐Vaughan, Denise

Publication type:

Article

Less means more: The magnitude of synaptic plasticity along the hippocampal dorso‐ventral axis is inversely related to the expression levels of plasticity‐related neurotransmitter receptors.

Published in:

Hippocampus, 2018, v. 28, n. 2, p. 136, doi. 10.1002/hipo.22816

By:

Dubovyk, Valentyna;
Manahan‐Vaughan, Denise

Publication type:

Article

Cover Image, Volume 28, Issue 2.

Published in:

Hippocampus, 2018, v. 28, n. 2, p. C1, doi. 10.1002/hipo.22772

By:

Dubovyk, Valentyna;
Manahan‐Vaughan, Denise

Publication type:

Article

Intrinsic cellular and molecular properties of in vivo hippocampal synaptic plasticity are altered in the absence of key synaptic matrix molecules.

Published in:

Hippocampus, 2017, v. 27, n. 8, p. 920, doi. 10.1002/hipo.22742

By:

Jansen, Stephan;
Gottschling, Christine;
Faissner, Andreas;
Manahan‐Vaughan, Denise

Publication type:

Article

The 5-hydroxytryptamine<sub>4</sub> receptor enables differentiation of informational content and encoding in the hippocampus.

Published in:

Hippocampus, 2016, v. 26, n. 7, p. 875, doi. 10.1002/hipo.22569

By:

Twarkowski, Hannah;
Hagena, Hardy;
Manahan‐Vaughan, Denise

Publication type:

Article

The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent.

Published in:

Hippocampus, 2016, v. 26, n. 6, p. 739, doi. 10.1002/hipo.22555

By:

Aarse, Janna;
Herlitze, Stefan;
Manahan‐Vaughan, Denise

Publication type:

Article

Hippocampal long-term potentiation that is elicited by perforant path stimulation or that occurs in conjunction with spatial learning is tightly controlled by beta-adrenoreceptors and the locus coeruleus.

Published in:

Hippocampus, 2015, v. 25, n. 11, p. 1285, doi. 10.1002/hipo.22436

By:

Hansen, Niels;
Manahan‐Vaughan, Denise

Publication type:

Article

The metabotropic glutamate receptor, mGlu5, is required for extinction learning that occurs in the absence of a context change.

Published in:

Hippocampus, 2015, v. 25, n. 2, p. 149, doi. 10.1002/hipo.22359

By:

André, Marion Agnes Emma;
Güntürkün, Onur;
Manahan‐Vaughan, Denise

Publication type:

Article

BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment.

Published in:

Hippocampus, 2015, v. 25, n. 1, p. 1, doi. 10.1002/hipo.22342

By:

Novkovic, Tanja;
Mittmann, Thomas;
Manahan‐Vaughan, Denise

Publication type:

Article

Antagonism of D1/ D5 receptors prevents long-term depression ( LTD) and learning-facilitated LTD at the perforant path-dentate gyrus synapse in freely behaving rats.

Published in:

Hippocampus, 2014, v. 24, n. 12, p. 1615, doi. 10.1002/hipo.22340

By:

Wiescholleck, Valentina;
Manahan‐Vaughan, Denise

Publication type:

Article

Place field stability requires the metabotropic glutamate receptor, mGlu5.

Published in:

Hippocampus, 2014, v. 24, n. 11, p. 1330, doi. 10.1002/hipo.22314

By:

Zhang, Sijie;
Manahan‐Vaughan, Denise

Publication type:

Article

Early age-dependent impairments of context-dependent extinction learning, object recognition, and object-place learning occur in rats.

Published in:

Hippocampus, 2014, v. 24, n. 3, p. 270, doi. 10.1002/hipo.22220

By:

Wiescholleck, Valentina;
Emma André, Marion Agnès;
Manahan‐Vaughan, Denise

Publication type:

Article

Hippocampal long-term depression in freely behaving mice requires the activation of beta-adrenergic receptors.

Published in:

Hippocampus, 2013, v. 23, n. 12, p. 1299, doi. 10.1002/hipo.22168

By:

Goh, Jinzhong Jeremy;
Manahan‐Vaughan, Denise

Publication type:

Article

Spatial olfactory learning facilitates long-term depression in the hippocampus.

Published in:

Hippocampus, 2013, v. 23, n. 10, p. 963, doi. 10.1002/hipo.22158

By:

André, Marion Agnès Emma;
Manahan‐Vaughan, Denise

Publication type:

Article

Endogenous hippocampal LTD that is enabled by spatial object recognition requires activation of NMDA receptors and the metabotropic glutamate receptor, mGlu5.

Published in:

Hippocampus, 2013, v. 23, n. 2, p. 129, doi. 10.1002/hipo.22072

By:

Goh, Jinzhong Jeremy;
Manahan‐Vaughan, Denise

Publication type:

Article

Frequency dependency of NMDA receptor-dependent synaptic plasticity in the hippocampal CA1 region of freely behaving mice.

Published in:

Hippocampus, 2012, v. 22, n. 12, p. 2238, doi. 10.1002/hipo.22041

By:

Buschler, Arne;
Goh, Jinzhong Jeremy;
Manahan-Vaughan, Denise

Publication type:

Article

A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats.

Published in:

Hippocampus, 2008, v. 18, n. 2, p. 125, doi. 10.1002/hipo.20367

By:

Manahan-Vaughan, Denise;
von Haebler, Dorothea;
Winter, Christine;
Juckel, Georg;
Heinemann, Uwe

Publication type:

Article

Modulation by group 1 metabotropic glutamate receptors of depotentiation in the dentate gyrus of freely moving rats.

Published in:

Hippocampus, 2008, v. 18, n. 1, p. 48, doi. 10.1002/hipo.20366

By:

Kulla, Alexander;
Manahan-Vaughan, Denise

Publication type:

Article

Synaptic plasticity in the adult visual cortex is regulated by the metabotropic glutamate receptor, mGLUR5.

Published in:

Experimental Brain Research, 2009, v. 199, n. 3/4, p. 391, doi. 10.1007/s00221-009-1965-4

By:

Tsanov, Marian;
Manahan-Vaughan, Denise

Publication type:

Article

Experience-Dependency of Reliance on Local Visual and Idiothetic Cues for Spatial Representations Created in the Absence of Distal Information.

Published in:

Frontiers in Behavioral Neuroscience, 2017, p. 1, doi. 10.3389/fnbeh.2017.00092

By:

Draht, Fabian;
Zhang, Sijie;
Rayan, Abdelrahman;
Schönfeld, Fabian;
Wiskott, Laurenz;
Manahan-Vaughan, Denise

Publication type:

Article

Changes in Neuronal Oscillations Accompany the Loss of Hippocampal LTP that Occurs in an Animal Model of Psychosis.

Published in:

Frontiers in Behavioral Neuroscience, 2017, v. 11, p. 1, doi. 10.3389/fnbeh.2017.00036

By:

Kalweit, Alexander N.;
Amanpour-Gharaei, Bezhad;
Colitti-Klausnitzer, Jens;
Manahan-Vaughan, Denise

Publication type:

Article

Editorial: Extinction Learning from a Mechanistic and Systems Perspective.

Published in:

2016

By:

Manahan-Vaughan, Denise;
Wolf, Oliver T.;
Güntürkün, Onur;
Sousa, Nuno

Publication type:

Editorial

Involvement of Dopamine D1/D5 and D2 Receptors in Context-Dependent Extinction Learning and Memory Reinstatement.

Published in:

Frontiers in Behavioral Neuroscience, 2016, p. 1, doi. 10.3389/fnbeh.2015.00372

By:

André, Marion Agnès Emma;
Manahan-Vaughan, Denise

Publication type:

Article

Beta-adrenergic receptors support attention to extinction learning that occurs in the absence, but not the presence, of a context change.

Published in:

Frontiers in Behavioral Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnbeh.2015.00125

By:

André, Marion Agnès Emma;
Wolf, Oliver T.;
Manahan-Vaughan, Denise

Publication type:

Article

Altered neuronal excitability underlies impaired hippocampal function in an animal model of psychosis.

Published in:

Frontiers in Behavioral Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnbeh.2015.00117

By:

Grüter, Thomas;
Wiescholleck, Valentina;
Dubovyk, Valentyna;
Aliane, Verena;
Manahan-Vaughan, Denise

Publication type:

Article

Spatial representations of place cells in darkness are supported by path integration and border information.

Published in:

Frontiers in Behavioral Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fnbeh.2014.00222

By:

Sijie Zhang;
Schonfeid, Fabian;
Wiskott, Laurenz;
Manahan-Vaughan, Denise

Publication type:

Article

Brief environmental enrichment elicits metaplasticity of hippocampal synaptic potentiation in vivo.

Published in:

Frontiers in Behavioral Neuroscience, 2012, v. 6, p. 1, doi. 10.3389/fnbeh.2012.00085

By:

Buschler, Arne;
Manahan-Vaughan, Denise

Publication type:

Article

Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00095

By:

Barmashenko, Gleb;
Buttgereit, Jens;
Herring, Neil;
Bader, Michael;
Özcelik, Cemil;
Manahan-Vaughan, Denise;
Braunewell, Karl H.

Publication type:

Article

Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13127-y

By:

Hagena, Hardy;
Feldmann, Mirko;
Manahan-Vaughan, Denise

Publication type:

Article

Afferent Input Selects NMDA Receptor Subtype to Determine the Persistency of Hippocampal LTP in Freely Behaving Mice.

Published in:

Frontiers in Synaptic Neuroscience, 2016, v. 8, p. 1, doi. 10.3389/fnsyn.2016.00033

By:

Ballesteros, Jesús J.;
Buschler, Arne;
Köhr, Georg;
Manahan-Vaughan, Denise

Publication type:

Article

Loss of Catecholaminergic Neuromodulation of Persistent Forms of Hippocampal Synaptic Plasticity with Increasing Age.

Published in:

Frontiers in Synaptic Neuroscience, 2016, p. 1, doi. 10.3389/fnsyn.2016.00030

By:

Twarkowski, Hannah;
Manahan-Vaughan, Denise

Publication type:

Article

Dopamine D1/D5, But not D2/D3, Receptor Dependency of Synaptic Plasticity at Hippocampal Mossy Fiber Synapses that Is Enabled by Patterned Afferent Stimulation, or Spatial Learning.

Published in:

Frontiers in Synaptic Neuroscience, 2016, p. 1, doi. 10.3389/fnsyn.2016.00031

By:

Hagena, Hardy;
Manahan-Vaughan, Denise

Publication type:

Article

Learning-facilitated synaptic plasticity occurs in the intermediate hippocampus in association with spatial learning.

Published in:

Frontiers in Synaptic Neuroscience, 2013, v. 5, p. 1, doi. 10.3389/fnsyn.2013.00010

By:

Kenney, Jana;
Manahan-Vaughan, Denise

Publication type:

Article

The temporoammonic hehippocampal CA1 region displays distinctly different synaptic plasticity compared to the Schaffer collateral input in vivo: significance for synaptic information processing.

Published in:

Frontiers in Synaptic Neuroscience, 2013, v. 5, p. 1, doi. 10.3389/fnsyn.2013.00005

By:

Aksoy-Aksel, Ayla;
Manahan-Vaughan, Denise

Publication type:

Article

Intracerebral inoculation of healthy non-transgenic rats with a single aliquot of oligomeric amyloid-β (1-42) profoundly and progressively alters brain function throughout life.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1397901

By:

Kramer, Marco;
Thu-Huong Hoang;
Honghong Yang;
Shchyglo, Olena;
Böge, Juliane;
Neubacher, Ute;
Colitti-Klausnitzer, Jens;
Manahan-Vaughan, Denise

Publication type:

Article

Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1373477

By:

Tarhan, Melih;
Hartl, Tim;
Shchyglo, Olena;
Colitti-Klausnitzer, Jens;
Kuhla, Angela;
Breuer, Tobias Maximilian;
Manahan-Vaughan, Denise

Publication type:

Article

GluN2A or GluN2B subunits of the NMDA receptor contribute to changes in neuronal excitability and impairments in LTP in the hippocampus of aging mice but do not mediate detrimental effects of oligomeric Aβ (1-42).

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1377085

By:

Südkamp, Nicolina;
Shchyglo, Olena;
Manahan-Vaughan, Denise

Publication type:

Article

Optogenetic Modulation and Multi-Electrode Analysis of Cerebellar Networks <i>In Vivo</i>.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105589

By:

Kruse, Wolfgang;
Krause, Martin;
Aarse, Janna;
Mark, Melanie D.;
Manahan-Vaughan, Denise;
Herlitze, Stefan

Publication type:

Article

Pannexin1 Stabilizes Synaptic Plasticity and Is Needed for Learning.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051767

By:

Prochnow, Nora;
Abdulazim, Amr;
Kurtenbach, Stefan;
Wildförster, Verena;
Dvoriantchikova, Galina;
Hanske, Julian;
Petrasch-Parwez, Elisabeth;
Shestopalov, Valery I.;
Dermietzel, Rolf;
Manahan-Vaughan, Denise;
Zoidl, Georg

Publication type:

Article

Identification of a Novel Signaling Pathway and Its Relevance for GluA1 Recycling.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033889

By:

Seebohm, Guiscard;
Neumann, Sebastian;
Theiss, Carsten;
Novkovic, Tanja;
Hill, Elaine V.;
Tavaré, Jeremy M.;
Lang, Florian;
Hollmann, Michael;
Manahan-Vaughan, Denise;
Strutz-Seeboh, Nathalie

Publication type:

Article

Long-Term Plasticity Is Proportional to Theta-Activity.

Published in:

PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005850

By:

Tsanov, Marian;
Manahan-Vaughan, Denise

Publication type:

Article