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Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial.
Published in:
2016
By:
- Johnston, Sebastian L.;
- Szigeti, Matyas;
- Brightling, Christopher;
- Chaudhuri, Rekha;
- Harrison, Timothy;
- Mansur, Adel;
- Robison, Laura;
- Sattar, Zahid;
- Jackson, David;
- Mallia, Patrick;
- Wong, Ernie;
- Corrigan, Christopher;
- Higgins, Bernard;
- Ind, Philip;
- Singh, Dave;
- Thomson, Neil C.;
- Ashby, Deborah;
- Chauhan, Anoop;
- Cross, Mary;
- AZALEA Trial Team
Publication type:
journal article
Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus.
Published in:
EMBO Molecular Medicine, 2012, v. 4, n. 12, p. 1244, doi. 10.1002/emmm.201201650
By:
- Bartlett, Nathan W.;
- Slater, Louise;
- Glanville, Nicholas;
- Haas, Jennifer J.;
- Caramori, Gaetano;
- Casolari, Paolo;
- Clarke, Deborah L.;
- Message, Simon D.;
- Aniscenko, Julia;
- Kebadze, Tatiana;
- Zhu, Jie;
- Mallia, Patrick;
- Mizgerd, Joseph P.;
- Belvisi, Maria;
- Papi, Alberto;
- Kotenko, Sergei V.;
- Johnston, Sebastian L.;
- Edwards, Michael R.
Publication type:
Article
Factors associated with reattendance to emergency services following COVID‐19 hospitalization.
Published in:
Journal of Medical Virology, 2021, v. 93, n. 3, p. 1250, doi. 10.1002/jmv.26594
By:
- Daunt, Anna;
- Perez‐Guzman, Pablo N.;
- Cafferkey, John;
- Manalan, Kavina;
- Cooke, Graham;
- White, Peter J.;
- Hauck, Katharina;
- Mallia, Patrick;
- Nayagam, Shevanthi
Publication type:
Article
Inflammation and infections in unreported chronic obstructive pulmonary disease exacerbations.
Published in:
International Journal of COPD, 2019, v. 14, p. 823, doi. 10.2147/COPD.S191946
By:
- Adelaide Calderazzo, Maria;
- Trujillo-Torralbo, Maria-Belen;
- Finney, Lydia Joanne;
- Singanayagam, Aran;
- Bakhsolian, Eteri;
- Padmanaban, Vijay;
- Kebadze, Tatiana;
- Aniscenko, Julia;
- Elkin, Sarah L.;
- Johnston, Sebastian L.;
- Mallia, Patrick
Publication type:
Article
Reduced sputum expression of interferon-stimulated genes in severe COPD.
Published in:
International Journal of COPD, 2016, v. 11, p. 1485, doi. 10.2147/copd.s105948
By:
- Hilzendeger, Clarissa;
- Silva, Jane da;
- Henket, Monique;
- Schleich, Florence;
- Corhay, Jean Louis;
- Kebadze, Tatiana;
- Edwards, Michael R.;
- Mallia, Patrick;
- Johnston, Sebastian L.;
- Louis, Renaud
Publication type:
Article
Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae.
Published in:
International Journal of COPD, 2014, v. 9, p. 1119, doi. 10.2147/COPD.S54477
By:
- Finney, Lydia J.;
- Ritchie, Andrew;
- Pollard, Elizabeth;
- Johnston, Sebastian L.;
- Mallia, Patrick
Publication type:
Article
Lung microbiology and exacerbations in COPD.
Published in:
International Journal of COPD, 2012, v. 7, p. 555, doi. 10.2147/COPD.S28286
By:
- Beasley, Victoria;
- Joshi, Priya V.;
- Singanayagam, Aran;
- Molyneaux, Philip L.;
- Johnston3, Sebastian L.;
- Mallia, Patrick
Publication type:
Article
Influenza infection and COPD.
Published in:
International Journal of COPD, 2007, v. 2, n. 1, p. 55, doi. 10.2147/copd.2007.2.1.55
By:
- Mallia, Patrick;
- Johnston, Sebastian L.
Publication type:
Article
Role of deficient type III interferon-λ production in asthma exacerbations.
Published in:
Nature Medicine, 2006, v. 12, n. 9, p. 1023, doi. 10.1038/nm1462
By:
- Contoli, Marco;
- Message, Simon D.;
- Laza-Stanca, Vasile;
- Edwards, Michael R.;
- Wark, Peter A. B.;
- Bartlett, Nathan W.;
- Kebadze, Tatiana;
- Mallia, Patrick;
- Stanciu, Luminita A.;
- Parker, Hayley L.;
- Slater, Louise;
- Lewis-Antes, Anita;
- Kon, Onn M.;
- Holgate, Stephen T.;
- Davies, Donna E.;
- Kotenko, Sergei V.;
- Papi, Alberto;
- Johnston, Sebastian L.
Publication type:
Article
RSV-Induced Bronchial Epithelial Cell PD-L1 Expression Inhibits CD8+ T Cell Nonspecific Antiviral Activity.
Published in:
Journal of Infectious Diseases, 2011, v. 203, n. 1, p. 85, doi. 10.1093/infdis/jiq020
By:
- Telcian, Aurica G.;
- Laza-Stanca, Vasile;
- Edwards, Michael R.;
- Harker, James A.;
- Wang, Hongwei;
- Bartlett, Nathan W.;
- Mallia, Patrick;
- Zdrenghea, Mihnea T.;
- Kebadze, Tatiana;
- Coyle, Anthony J.;
- Openshaw, Peter J.M.;
- Stanciu, Luminita A.;
- Johnston, Sebastian L.
Publication type:
Article
Innate-like Gene Expression of Lung-Resident Memory CD8<sup>+</sup> T Cells during Experimental Human Influenza: A Clinical Study.
Published in:
2021
By:
- Paterson, Suzanna;
- Kar, Satwik;
- Ung, Seng Kuong;
- Gardener, Zoe;
- Bergstrom, Emma;
- Ascough, Stephanie;
- Kalyan, Mohini;
- Zyla, Joanna;
- Maertzdorf, Jeroen;
- Mollenkopf, Hans-Joachim;
- Weiner, January;
- Jozwik, Agnieszka;
- Jarvis, Hannah;
- Jha, Akhilesh;
- Nicholson, Bradly P.;
- Veldman, Timothy;
- Woods, Chris W.;
- Mallia, Patrick;
- Kon, Onn Min;
- Kaufmann, Stefan H. E.
Publication type:
journal article
Targeted Retreatment of Incompletely Recovered Chronic Obstructive Pulmonary Disease Exacerbations with Ciprofloxacin. A Double-Blind, Randomized, Placebo-controlled, Multicenter, Phase III Clinical Trial.
Published in:
2020
By:
- Ritchie, Andrew I.;
- Brill, Simon E.;
- Vlies, Ben H.;
- Finney, Lydia J.;
- Allinson, James P.;
- Alves-Moreira, Luana;
- Wiseman, Dexter J.;
- Walker, Paul P.;
- Baker, Emma;
- Elkin, Sarah L.;
- Mallia, Patrick;
- Law, Martin;
- Donaldson, Gavin C.;
- Calverley, Peter M. A.;
- Wedzicha, Jadwiga A.
Publication type:
journal article
Human Rhinovirus Impairs the Innate Immune Response to Bacteria in Alveolar Macrophages in Chronic Obstructive Pulmonary Disease.
Published in:
2019
By:
- Finney, Lydia J;
- Belchamber, Kylie B R;
- Fenwick, Peter S;
- Kemp, Samuel V;
- Edwards, Michael R;
- Mallia, Patrick;
- Donaldson, Gavin;
- Johnston, Sebastian L;
- Donnelly, Louise E;
- Wedzicha, Jadwiga A
Publication type:
journal article
Neutrophil adhesion molecules in experimental rhinovirus infection in COPD.
Published in:
Respiratory Research, 2013, v. 14, n. 7, p. 1, doi. 10.1186/1465-9921-14-72
By:
- Mallia, Patrick;
- Message, Simon D.;
- Contoli, Marco;
- Gray, Katrina K.;
- Telcian, Aurica;
- Laza-Stanca, Vasile;
- Papi, Alberto;
- Stanciu, Luminita A.;
- Elkin, Sarah;
- Kon, Onn M.;
- Johnson, Malcolm;
- Johnston, Sebastian L.
Publication type:
Article
Neutrophil adhesion molecules in experimental rhinovirus infection in COPD.
Published in:
2013
By:
- Mallia, Patrick;
- Message, Simon D;
- Contoli, Marco;
- Gray, Katrina K;
- Telcian, Aurica;
- Laza-Stanca, Vasile;
- Papi, Alberto;
- Stanciu, Luminita A;
- Elkin, Sarah;
- Kon, Onn M;
- Johnson, Malcolm;
- Johnston, Sebastian L
Publication type:
journal article
An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study.
Published in:
Respiratory Research, 2006, v. 7, p. 116, doi. 10.1186/1465-9921-7-116
By:
- Mallia, Patrick;
- Message, Simon D.;
- Kebadze, Tatiana;
- Parker, Hayley L.;
- Kon, Onn M.;
- Johnston, Sebastian L.
Publication type:
Article
Chest CT features and functional correlates of COVID-19 at 3 months and 12 months follow-up.
Published in:
Clinical Medicine, 2023, v. 23, n. 5, p. 467, doi. 10.7861/clinmed.2023-0059
By:
- Kumar, Kartik;
- Ratnakumar, Ratnaprashanthika;
- Collin, Simon M.;
- Berrocal-Almanza, Luis C.;
- Ricci, Piera;
- Al-Zubaidy, Mustafa;
- Coker, Robina K.;
- Coleman, Meg;
- Elkin, Sarah L.;
- Mallia, Patrick;
- Meghji, Jamilah;
- Ross, Clare;
- Russell, Georgina K.;
- Ward, Katie;
- Wickremasinghe, Melissa;
- Sheard, Sarah;
- Copley, Susan J.;
- Onn Min Kon
Publication type:
Article
Lesson of the month 2: A case of nitrous oxide-induced pancytopenia.
Published in:
Clinical Medicine, 2019, v. 19, n. 2, p. 129, doi. 10.7861/clinmedicine.19-2-129
By:
- Norris, Felicity;
- Mallia, Patrick
Publication type:
Article
The role of viral infections in exacerbations of chronic obstructive pulmonary disease and asthma.
Published in:
Therapeutic Advances in Respiratory Disease, 2016, v. 10, n. 2, p. 158, doi. 10.1177/1753465815618113
By:
- Hewitt, Richard;
- Farne, Hugo;
- Ritchie, Andrew;
- Luke, Emma;
- Johnston, Sebastian L.;
- Mallia, Patrick
Publication type:
Article
Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection.
Published in:
2020
By:
- Guvenel, Aleks;
- Jozwik, Agnieszka;
- Ascough, Stephanie;
- Seng Kuong Ung;
- Paterson, Suzanna;
- Kalyan, Mohini;
- Gardener, Zoe;
- Bergstrom, Emma;
- Kar, Satwik;
- Habibi, Maximillian S.;
- Paras, Allan;
- Jie Zhu;
- Park, Mirae;
- Dhariwal, Jaideep;
- Almond, Mark;
- Wong, Ernie H. C.;
- Sykes, Annemarie;
- Del Rosario, Jerico;
- Trujillo-Torralbo, Maria-Belen;
- Mallia, Patrick
Publication type:
journal article
Epitope-specific airway-resident CD4<sup>+</sup> T cell dynamics during experimental human RSV infection.
Published in:
Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 523, doi. 10.1172/JCI131696
By:
- Guvenel, Aleks;
- Jozwik, Agnieszka;
- Ascough, Stephanie;
- Seng Kuong Ung;
- Paterson, Suzanna;
- Kalyan, Mohini;
- Gardener, Zoe;
- Bergstrom, Emma;
- Kar, Satwik;
- Habibi, Maximillian S.;
- Paras, Allan;
- Jie Zhu;
- Park, Mirae;
- Dhariwal, Jaideep;
- Almond, Mark;
- Wong, Ernie H. C.;
- Sykes, Annemarie;
- Del Rosario, Jerico;
- Trujillo-Torralbo, Maria-Belen;
- Mallia, Patrick
Publication type:
Article
Erratum: RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.
Published in:
Nature Communications, 2016, v. 7, n. 3, p. 11011, doi. 10.1038/ncomms11011
By:
- Jozwik, Agnieszka;
- Habibi, Maximillian S.;
- Paras, Allan;
- Zhu, Jie;
- Guvenel, Aleks;
- Dhariwal, Jaideep;
- Almond, Mark;
- Wong, Ernie H. C.;
- Sykes, Annemarie;
- Maybeno, Matthew;
- Del Rosario, Jerico;
- Trujillo-Torralbo, Maria-Belen;
- Mallia, Patrick;
- Sidney, John;
- Peters, Bjoern;
- Kon, Onn Min;
- Sette, Alessandro;
- Johnston, Sebastian L.;
- Openshaw, Peter J.;
- Chiu, Christopher
Publication type:
Article
RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.
Published in:
Nature Communications, 2015, v. 6, n. 12, p. 10224, doi. 10.1038/ncomms10224
By:
- Jozwik, Agnieszka;
- Habibi, Maximillian S.;
- Paras, Allan;
- Zhu, Jie;
- Guvenel, Aleks;
- Dhariwal, Jaideep;
- Almond, Mark;
- Wong, Ernie H. C.;
- Sykes, Annemarie;
- Maybeno, Matthew;
- Del Rosario, Jerico;
- Trujillo-Torralbo, Maria-Belen;
- Mallia, Patrick;
- Sidney, John;
- Peters, Bjoern;
- Kon, Onn Min;
- Sette, Alessandro;
- Johnston, Sebastian L.;
- Openshaw, Peter J.;
- Chiu, Christopher
Publication type:
Article
Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease.
Published in:
Science Translational Medicine, 2019, v. 11, n. 507, p. 1, doi. 10.1126/scitranslmed.aav3879
By:
- Singanayagam, Aran;
- Glanville, Nicholas;
- Cuthbertson, Leah;
- Bartlett, Nathan W.;
- Finney, Lydia J.;
- Turek, Elena;
- Bakhsoliani, Eteri;
- Calderazzo, Maria Adelaide;
- Trujillo-Torralbo, Maria-Belen;
- Footitt, Joseph;
- James, Phillip L.;
- Fenwick, Peter;
- Kemp, Samuel V.;
- Clarke, Thomas B.;
- Wedzicha, Jadwiga A.;
- Edwards, Michael R.;
- Moffatt, Miriam;
- Cookson, William O.;
- Mallia, Patrick;
- Johnston, Sebastian L.
Publication type:
Article
Interleukin-18 Is Associated With Protection Against Rhinovirus-Induced Colds and Asthma Exacerbations.
Published in:
Clinical Infectious Diseases, 2015, v. 60, n. 10, p. 1528, doi. 10.1093/cid/civ062
By:
- Jackson, David J.;
- Glanville, Nicholas;
- Trujillo-Torralbo, Maria-Belen;
- Shamji, Betty W. H.;
- del-Rosario, Jerico;
- Mallia, Patrick;
- Edwards, Matthew J.;
- Walton, Ross P.;
- Edwards, Michael R.;
- Johnston, Sebastian L.
Publication type:
Article
The Role of Bacteria in the Pathogenesis and Progression of Idiopathic Pulmonary Fibrosis.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 8, p. 906, doi. 10.1164/rccm.201403-0541OC
By:
- Molyneaux, Phillip L.;
- Cox, Michael J.;
- Willis-Owen, Saffron A. G.;
- Mallia, Patrick;
- Russell, Kirsty E.;
- Russell, Anne-Marie;
- Murphy, Elissa;
- Johnston, Sebastian L.;
- Schwartz, David A.;
- Wells, Athol U.;
- Cookson, William O. C.;
- Maher, Toby M.;
- Moffatt, Miriam F.
Publication type:
Article
Outgrowth of the Bacterial Airway Microbiome after Rhinovirus Exacerbation of Chronic Obstructive Pulmonary Disease.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2013, v. 188, n. 10, p. 1224, doi. 10.1164/rccm.201302-0341OC
By:
- Molyneaux, Philip L.;
- Mallia, Patrick;
- Cox, Michael J.;
- Footitt, Joseph;
- Willis-Owen, Saffron A. G.;
- Homola, Daniel;
- Trujillo-Torralbo, Maria-Belen;
- Elkin, Sarah;
- Kon, Onn Min;
- Cookson, William O. C.;
- Moffatt, Miriam F.;
- Johnston, Sebastian L.
Publication type:
Article
Rhinovirus Infection Induces Degradation of Antimicrobial Peptides and Secondary Bacterial Infection in Chronic Obstructive Pulmonary Disease.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2012, v. 186, n. 11, p. 1117, doi. 10.1164/rccm.201205-0806OC
By:
- Mallia, Patrick;
- Footitt, Joseph;
- Sotero, Rosa;
- Jepson, Annette;
- Contoli, Marco;
- Trujillo-Torralbo, Maria-Belen;
- Kebadze, Tatiana;
- Aniscenko, Julia;
- Oleszkiewicz, Gregory;
- Gray, Katrina;
- Message, Simon D.;
- Ito, Kazuhiro;
- Barnes, Peter J.;
- Adcock, Ian M.;
- Papi, Alberto;
- Stanciu, Luminita A.;
- Elkin, Sarah L.;
- Kon, Onn M.;
- Johnson, Malcolm;
- Johnston, Sebastian L.
Publication type:
Article
The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations.
Published in:
PLoS Pathogens, 2011, v. 7, n. 7, p. 1, doi. 10.1371/journal.ppat.1002114
By:
- Laza-Stanca, Vasile;
- Message, Simon D.;
- Edwards, Michael R.;
- Parker, Hayley L.;
- Zdrenghea, Mihnea T.;
- Kebadze, Tatiana;
- Kon, Onn M.;
- Mallia, Patrick;
- Stanciu, Luminita A.;
- Johnston, Sebastian L.
Publication type:
Article
Immunological pathways in virus-induced COPD exacerbations: a role for IL-15.
Published in:
European Journal of Clinical Investigation, 2012, v. 42, n. 9, p. 1010, doi. 10.1111/j.1365-2362.2012.02672.x
By:
- Zdrenghea, Mihnea T.;
- Mallia, Patrick;
- Johnston, Sebastian L.
Publication type:
Article
The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD.
Published in:
PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146102
By:
- Russell, Kirsty E.;
- Chung, Kian Fan;
- Clarke, Colin J.;
- Durham, Andrew L.;
- Mallia, Patrick;
- Footitt, Joseph;
- Johnston, Sebastian L.;
- Barnes, Peter J.;
- Hall, Simon R.;
- Simpson, Karen D.;
- Starkey, Malcolm R.;
- Hansbro, Philip M.;
- Adcock, Ian M.;
- Wiegman, Coen H.
Publication type:
Article
Experimental Antiviral Therapeutic Studies for Human Rhinovirus Infections.
Published in:
Journal of Experimental Pharmacology, 2021, v. 13, p. 645, doi. 10.2147/JEP.S255211
By:
- Coultas, James A;
- Cafferkey, John;
- Mallia, Patrick;
- Johnston, Sebastian L
Publication type:
Article
Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04574-1
By:
- Singanayagam, Aran;
- Glanville, Nicholas;
- Yee Man Ching;
- Marcellini, Andrea;
- Porter, James D.;
- Toussaint, Marie;
- Walton, Ross P.;
- Finney, Lydia J.;
- Aniscenko, Julia;
- Jie Zhu;
- Trujillo-Torralbo, Maria-Belen;
- Calderazzo, Maria Adelaide;
- Solari, Roberto;
- Edwards, Michael R.;
- Mallia, Patrick;
- Johnston, Sebastian L.;
- Bartlett, Nathan W.;
- Girkin, Jason L.;
- Grainge, Chris;
- Su-Ling Loo
Publication type:
Article
T regulatory cells from atopic asthmatic individuals show a Th2‐like phenotype.
Published in:
Allergy, 2022, v. 77, n. 4, p. 1320, doi. 10.1111/all.15193
By:
- Jansen, Kirstin;
- Satitsuksanoa, Pattraporn;
- Wirz, Oliver F.;
- Schneider, Stephan R.;
- van de Veen, Willem;
- Tan, Ge;
- Sokolowska, Milena;
- Message, Simon D.;
- Kebadze, Tatiana;
- Glanville, Nicholas;
- Mallia, Patrick;
- Akdis, Cezmi A.;
- Moniuszko, Marcin;
- Johnston, Sebastian L.;
- Nadeau, Kari;
- Akdis, Mübeccel
Publication type:
Article
Experimental rhinovirus infection induces an antiviral response in circulating B cells which is dysregulated in patients with asthma.
Published in:
Allergy, 2022, v. 77, n. 1, p. 130, doi. 10.1111/all.14985
By:
- Wirz, Oliver F.;
- Jansen, Kirstin;
- Satitsuksanoa, Pattraporn;
- van de Veen, Willem;
- Tan, Ge;
- Sokolowska, Milena;
- Mirer, David;
- Stanić, Barbara;
- Message, Simon D.;
- Kebadze, Tatiana;
- Glanville, Nicholas;
- Mallia, Patrick;
- Gern, James E.;
- Papadopoulos, Nikolaos;
- Akdis, Cezmi A.;
- Johnston, Sebastian L.;
- Nadeau, Kari;
- Akdis, Mübeccel
Publication type:
Article
Pathogenesis of Viral Infection in Exacerbations of Airway Disease.
Published in:
2015
By:
- Ritchie, Andrew I.;
- Farne, Hugo A.;
- Singanayagam, Aran;
- Jackson, David J.;
- Mallia, Patrick;
- Johnston, Sebastian L.
Publication type:
journal article
Asthma-COPD Overlap Syndrome: A Review of Current Knowledge and Future Directions.
Published in:
Malta Medical Journal, 2017, v. 29, n. 2, p. 22
By:
- Mallia, Patrick;
- Johnston, Sebastian L.
Publication type:
Article
Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma.
Published in:
PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183864
By:
- Upton, Nadine;
- Jackson, David J.;
- Nikonova, Alexandra A.;
- Hingley-Wilson, Suzie;
- Khaitov, Musa;
- del Rosario, Ajerico;
- Traub, Stephanie;
- Trujillo-Torralbo, Maria-Belen;
- Habibi, Max;
- Elkin, Sarah L.;
- Kon, Onn M.;
- Edwards, Michael R.;
- Mallia, Patrick;
- Footitt, Joseph;
- Macintyre, Jonathan;
- Stanciu, Luminita A.;
- Johnston, Sebastian L.;
- Sykes, Annemarie
Publication type:
Article

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