Works by Malina, Jaroslav

Results: 41

Optically pure, water-stable metallo-helical 'flexicate' assemblies with antibiotic activity.

Published in:

Nature Chemistry, 2012, v. 4, n. 1, p. 31, doi. 10.1038/nchem.1206

By:

Howson, Suzanne E.;
Bolhuis, Albert;
Brabec, Viktor;
Clarkson, Guy J.;
Malina, Jaroslav;
Rodger, Alison;
Scott, Peter

Publication type:

Article

FeII Metallohelices Stabilize DNA G‐Quadruplexes and Downregulate the Expression of G‐Quadruplex‐Regulated Oncogenes.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 45, p. 11682, doi. 10.1002/chem.202101388

By:

Malina, Jaroslav;
Kostrhunova, Hana;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

On the Biology of Werner's Complex.

Published in:

Angewandte Chemie, 2021, v. 133, n. 31, p. 17260, doi. 10.1002/ange.202105019

By:

Paiva, Raphael E. F.;
Peterson, Erica J.;
Malina, Jaroslav;
Zoepfl, Mary;
Hampton, J. David;
Johnson, Wyatt E.;
Graminha, Angelica;
Ourahmane, Amine;
McVoy, Michael A.;
Brabec, Viktor;
Berners‐Price, Susan J.;
Farrell, Nicholas P.

Publication type:

Article

Substitution‐Inert Polynuclear Platinum Complexes That Inhibit the Activity of DNA Polymerase in Triplex‐Forming Templates.

Published in:

Angewandte Chemie, 2018, v. 130, n. 28, p. 8671, doi. 10.1002/ange.201803448

By:

Malina, Jaroslav;
Farrell, Nicholas P.;
Brabec, Viktor

Publication type:

Article

Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 2, p. 720, doi. 10.1093/nar/gkq803

By:

Malina, Jaroslav;
Kasparkova, Jana;
Farrell, Nicholas P.;
Brabec, Viktor

Publication type:

Article

Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 16, p. 5432, doi. 10.1093/nar/gkp580

By:

Malina, Jaroslav;
Vrana, Oldrich;
Brabec, Viktor

Publication type:

Article

DNA binding of dinuclear iron(II) metallosupramolecular cylinders. DNA unwinding and sequence preference.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 11, p. 3630, doi. 10.1093/nar/gkn244

By:

Malina, Jaroslav;
Hannon, Michael J.;
Brabec, Viktor

Publication type:

Article

DNA–protein cross‐linking by trans‐[PtCl2(E‐iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 22, p. 6450, doi. 10.1093/nar/gkg863

By:

Novakova, Olga;
Kasparkova, Jana;
Malina, Jaroslav;
Natile, Giovanni;
Brabec, Viktor

Publication type:

Article

Recognition of DNA bulges by dinuclear iron( II) metallosupramolecular helicates.

Published in:

2014

By:

Malina, Jaroslav;
Hannon, Michael J.;
Brabec, Viktor

Publication type:

Editorial

Probing the Thermodynamics of Incorporation of N6‐methyl‐dATP Opposite an Abasic Site, dCMP, and dTMP During Simulated DNA Synthesis by Differential Scanning Calorimetry.

Published in:

ChemistrySelect, 2018, v. 3, n. 46, p. 13076, doi. 10.1002/slct.201803565

By:

Malina, Jaroslav;
Brabec, Viktor

Publication type:

Article

Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cells.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2198678

By:

Malina, Jaroslav;
Kostrhunova, Hana;
Song, Hualong;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

On the Biology of Werner's Complex.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 31, p. 17123, doi. 10.1002/anie.202105019

By:

de Paiva, Raphael E. F.;
Peterson, Erica J.;
Malina, Jaroslav;
Zoepfl, Mary;
Hampton, J. David;
Johnson, Wyatt E.;
Graminha, Angelica;
Ourahmane, Amine;
McVoy, Michael A.;
Brabec, Viktor;
Berners‐Price, Susan J.;
Farrell, Nicholas P.

Publication type:

Article

Cationic FeII Triplex‐Forming Metallohelices as DNA Bulge Binders.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 69, p. 16554, doi. 10.1002/chem.202004060

By:

Hrabina, Ondrej;
Malina, Jaroslav;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

Shape‐Selective Targeting on RNA Bulges by Peptidomimetic Metallohelices.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 38, p. 8435, doi. 10.1002/chem.202001107

By:

Malina, Jaroslav;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

Substitution‐Inert Polynuclear Platinum Complexes Act as Potent Inducers of Condensation/Aggregation of Short Single‐ and Double‐Stranded DNA and RNA Oligonucleotides.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 12, p. 2995, doi. 10.1002/chem.201806276

By:

Malina, Jaroslav;
Farrell, Nicholas P.;
Brabec, Viktor

Publication type:

Article

Architekt ↔ Potencolog (Janu Velkovi k pětaedesátinám).

Published in:

Anthropologia Integra, 2017, v. 8, n. 1, p. 56

By:

MALINA, JAROSLAV

Publication type:

Article

Sexāgēnārius ↔ Gigant (Makarónsky Václavu Soukupovi k edesátinám).

Published in:

Anthropologia Integra, 2017, v. 8, n. 1, p. 55

By:

MALINA, JAROSLAV

Publication type:

Article

Iron(II) Supramolecular Helicates Condense Plasmid DNA and Inhibit Vital DNA-Related Enzymatic Activities.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 31, p. 11189, doi. 10.1002/chem.201501307

By:

Malina, Jaroslav;
Hannon, Michael J.;
Brabec, Viktor

Publication type:

Article

Thermodynamic Impact of Abasic Sites on Simulated Translesion DNA Synthesis.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 25, p. 7566, doi. 10.1002/chem.201402600

By:

Malina, Jaroslav;
Brabec, Viktor

Publication type:

Article

Spontaneous Translocation of Antitumor Oxaliplatin, its Enantiomeric Analogue, and Cisplatin from One Strand to Another in Double-Helical DNA.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 36, p. 11984, doi. 10.1002/chem.201300946

By:

Malina, Jaroslav;
Natile, Giovanni;
Brabec, Viktor

Publication type:

Article

Thermodynamic and Mechanistic Insights into Translesion DNA Synthesis Catalyzed by Y-Family DNA Polymerase Across a Bulky Double-Base Lesion of an Antitumor Platinum Drug.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 48, p. 15439, doi. 10.1002/chem.201202117

By:

Brabec, Viktor;
Malina, Jaroslav;
Margiotta, Nicola;
Natile, Giovanni;
Kasparkova, Jana

Publication type:

Article

Substitution-Inert Trinuclear Platinum Complexes Efficiently Condense/Aggregate Nucleic Acids and Inhibit Enzymatic Activity.

Published in:

Angewandte Chemie, 2014, v. 126, n. 47, p. 13026, doi. 10.1002/ange.201408012

By:

Malina, Jaroslav;
Farrell, Nicholas P.;
Brabec, Viktor

Publication type:

Article

Metallohelices stabilize DNA three-way junctions and induce DNA damage in cancer cells.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 14, p. 7174, doi. 10.1093/nar/gkad536

By:

Malina, Jaroslav;
Kostrhunova, Hana;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 2, p. 674, doi. 10.1093/nar/gkab1277

By:

Malina, Jaroslav;
Kostrhunova, Hana;
Novohradsky, Vojtech;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 11, p. 5297, doi. 10.1093/nar/gkv438

By:

Malina, Jaroslav;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

The Thermodynamics of Translesion DNA Synthesis Past Major Adducts of Enantiomeric Analogues of Antitumor Cisplatin.

Published in:

Chemistry - An Asian Journal, 2012, v. 7, n. 5, p. 1026, doi. 10.1002/asia.201100886

By:

Malina, Jaroslav;
Novakova, Olga;
Natile, Giovanni;
Brabec, Viktor

Publication type:

Article

DNA Interstrand Cross-Links of an Antitumor Trinuclear Platinum(II) Complex: Thermodynamic Analysis and Chemical Probing.

Published in:

Chemistry - An Asian Journal, 2011, v. 6, n. 6, p. 1566, doi. 10.1002/asia.201000935

By:

Malina, Jaroslav;
Farrell, Nicholas P.;
Brabec, Viktor

Publication type:

Article

Stabilization of human telomeric RNA G-quadruplex by the water-compatible optically pure and biologically-active metallohelices.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71429-5

By:

Malina, Jaroslav;
Scott, Peter;
Brabec, Viktor

Publication type:

Article

Reply to comments.

Published in:

Norwegian Archaeological Review, 1983, v. 16, n. 2, p. 83, doi. 10.1080/00293652.1983.9965389

By:

Malina, Jaroslav

Publication type:

Article

Archaeology and experiment.

Published in:

Norwegian Archaeological Review, 1983, v. 16, n. 2, p. 69, doi. 10.1080/00293652.1983.9965385

By:

Malina, Jaroslav

Publication type:

Article

Energetics, Conformation, and Recognition of DNA Duplexes Modified by Monodentate RuII Complexes Containing Terphenyl Arenes.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 19, p. 5744, doi. 10.1002/chem.200903078

By:

Novakova, Olga;
Malina, Jaroslav;
Suchankova, Tereza;
Kasparkova, Jana;
Bugarcic, Tijana;
Sadler, Peter J.;
Brabec, Viktor

Publication type:

Article

Interaction of Dinuclear Ruthenium(II) Supramolecular Cylinders with DNA: Sequence-Specific Binding, Unwinding, and Photocleavage.

Published in:

Chemistry - A European Journal, 2008, v. 14, n. 33, p. 10408, doi. 10.1002/chem.200801364

By:

Malina, Jaroslav;
Hannon, Michael J.;
Brabec, Viktor

Publication type:

Article

Recognition of DNA Three-Way Junctions by Metallosupramolecular Cylinders: Gel Electrophoresis Studies.

Published in:

Chemistry - A European Journal, 2007, v. 13, n. 14, p. 3871, doi. 10.1002/chem.200700159

By:

Malina, Jaroslav;
Hannon, Michael J.;
Brabec, Viktor

Publication type:

Article

A DNA-Binding Copper(I) Metallosupramolecular Cylinder that Acts as an Artificial Nuclease.

Published in:

Chemistry - A European Journal, 2006, v. 12, n. 18, p. 4919, doi. 10.1002/chem.200600060

By:

Laura J. Childs;
Jaroslav Malina;
Britt Elin Rolfsnes;
Mirela Pascu;
Maria J. Prieto;
Mark J. Broome;
P. Mark Rodger;
Einar Sletten;
Virtudes Moreno;
Alison Rodger;
Michael J. Hannon

Publication type:

Article

Design and DNA Binding of an Extended Triple-Stranded Metallo-supramolecular Cylinder.

Published in:

Chemistry - A European Journal, 2005, v. 11, n. 6, p. 1750, doi. 10.1002/chem.200401054

By:

Carsten Uerpmann;
Jaroslav Malina;
Mirela Pascu;
Guy J. Clarkson;
Virtudes Moreno;
Alison Rodger;
Anna Grandas;
Michael J. Hannon

Publication type:

Article

Substitution‐Inert Polynuclear Platinum Complexes That Inhibit the Activity of DNA Polymerase in Triplex‐Forming Templates.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 28, p. 8535, doi. 10.1002/anie.201803448

By:

Malina, Jaroslav;
Farrell, Nicholas P.;
Brabec, Viktor

Publication type:

Article

Substitution-Inert Trinuclear Platinum Complexes Efficiently Condense/Aggregate Nucleic Acids and Inhibit Enzymatic Activity.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 47, p. 12812, doi. 10.1002/anie.201408012

By:

Malina, Jaroslav;
Farrell, Nicholas P.;
Brabec, Viktor

Publication type:

Article

NMR analysis of duplex d(CGCGATCGCG)2 modified by Λ- and Δ-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2007, v. 12, n. 3, p. 279, doi. 10.1007/s00775-006-0184-8

By:

Myari, Alexandra;
Hadjiliadis, Nick;
Garoufis, Achilleas;
Malina, Jaroslav;
Brabec, Viktor

Publication type:

Article

NMR analysis of duplex d(CGCGATCGCG)2 modified by Λ- and Δ-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study.

Published in:

2007

By:

Myari, Alexandra;
Hadjiliadis, Nick;
Garoufis, Achilleas;
Malina, Jaroslav;
Brabec, Viktor

Publication type:

Correction Notice

Iron(II) supramolecular helicates interfere with the HIV-1 Tat-TAR RNA interaction critical for viral replication.

Published in:

Scientific Reports, 2016, p. 29674, doi. 10.1038/srep29674

By:

Malina, Jaroslav;
Hannon, Michael J.;
Brabec, Viktor

Publication type:

Article

Ni(II) Cylinders Damage DNA in Cancer Cells and Preferentially Bind Y‐Shaped DNA Three‐Way Junctions Blocking DNA Synthesis.

Published in:

Small, 2024, v. 20, n. 52, p. 1, doi. 10.1002/smll.202406814

By:

Malina, Jaroslav;
Kostrhunova, Hana;
Brabec, Viktor

Publication type:

Article