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Octanol/water partition coefficients estimated using retention times in reverse-phase liquid chromatography and calculated in silico as one of the determinant factors for pharmacokinetic parameter estimations of general chemical substances.
- Published in:
- Journal of Toxicological Sciences, 2024, v. 49, n. 4, p. 127, doi. 10.2131/jts.49.127
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- Publication type:
- Article
Deschloroclozapine exhibits an exquisite agonistic effect at lower concentration compared to clozapine-N-oxide in hM3Dq expressing chemogenetically modified rats.
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- Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1301515
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- Publication type:
- Article
Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection.
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- Journal of Pharmaceutical Health Care & Sciences, 2023, v. 9, n. 1, p. 1, doi. 10.1186/s40780-023-00303-z
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- Publication type:
- Article
Metabolic Syndrome and the Increased Risk of Medically Certified Long-term Sickness Absence: A Prospective Analysis Among Japanese Workers.
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- Journal of Epidemiology, 2023, v. 33, n. 6, p. 311, doi. 10.2188/jea.JE20210185
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- Publication type:
- Article
Forward and reverse dosimetry for aniline and 2,6-dimethylaniline in humans extrapolated from humanized-liver mouse data using simplified physiologically based pharmacokinetic models.
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- Journal of Toxicological Sciences, 2022, v. 47, n. 12, p. 531, doi. 10.2131/jts.47.531
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- Publication type:
- Article
Updated in silico prediction methods for fractions absorbed and absorption rate constants of 372 disparate chemicals for use in physiologically based pharmacokinetic models for estimating internal concentrations in rats.
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- Journal of Toxicological Sciences, 2022, v. 47, n. 11, p. 453, doi. 10.2131/jts.47.453
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- Publication type:
- Article
Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03879-8
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- Publication type:
- Article
Diagnosis-specific Cumulative Incidence of Return-to-work, Resignation, and Death Among Long-term Sick-listed Employees: Findings From the Japan Epidemiology Collaboration on Occupational Health Study.
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- Journal of Epidemiology, 2022, v. 32, n. 9, p. 431, doi. 10.2188/jea.JE20200541
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- Publication type:
- Article
Expression of oxytocin in hypothalamus and reduction of nociceptive stress following administration of Kamikihi-to in female rats.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.961135
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- Publication type:
- Article
Plasma and synovial fluid concentrations of linezolid in patients with knee osteoarthritis infected with Staphylococcus aureus.
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- Journal of Pharmaceutical Health Care & Sciences, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s40780-022-00248-9
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- Publication type:
- Article
Pharmacokinetics of primary metabolites 5-hydroxythalidomide and 5'-hydroxythalidomide formed after oral administration of thalidomide in the rabbit, a thalidomide-sensitive species.
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- Journal of Toxicological Sciences, 2021, v. 46, n. 12, p. 553, doi. 10.2131/jts.46.553
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- Publication type:
- Article
Roles of human cytochrome P450 1A2 in coumarin 3,4-epoxidation mediated by untreated hepatocytes and by those metabolically inactivated with furafylline in previously transplanted chimeric mice.
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- Journal of Toxicological Sciences, 2021, v. 46, n. 11, p. 525, doi. 10.2131/jts.46.525
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- Article
Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital.
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- Journal of Pharmaceutical Health Care & Sciences, 2021, v. 7, n. 1, p. 1, doi. 10.1186/s40780-021-00220-z
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- Publication type:
- Article
Pharmacokinetics of loxoprofen in a self-administered overdose in a Japanese patient admitted to hospital.
- Published in:
- 2021
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- Publication type:
- Case Study
Metabolic profiles for the pyrrolizidine alkaloid neopetasitenine and its metabolite petasitenine in humans extrapolated from rat in vivo and in vitro data sets using a simplified physiologically based pharmacokinetic model.
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- Journal of Toxicological Sciences, 2021, v. 46, n. 9, p. 391, doi. 10.2131/jts.46.391
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- Publication type:
- Article
Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital.
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- Journal of Pharmaceutical Health Care & Sciences, 2021, v. 7, n. 1, p. 1, doi. 10.1186/s40780-021-00215-w
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- Publication type:
- Article
Visit-to-visit variability of blood pressure and cardiovascular events among the working-age population in Japan: findings from the Japan Epidemiology Collaboration on Occupational Health Study.
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- Hypertension Research, 2021, v. 44, n. 8, p. 1017, doi. 10.1038/s41440-021-00654-w
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- Publication type:
- Article
Loss of Working Life Years Due to Mortality, Sickness Absence, or Ill-health Retirement: A Comprehensive Approach to Estimating Disease Burden in the Workplace.
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- Journal of Epidemiology, 2021, v. 31, n. 7, p. 403, doi. 10.2188/jea.JE20190332
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- Publication type:
- Article
Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention against colorectal tumors in single Japanese cohort using daily low-dose aspirin: insights into future personalized treatments.
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- Journal of Pharmaceutical Health Care & Sciences, 2021, v. 7, n. 1, p. 1, doi. 10.1186/s40780-021-00209-8
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- Publication type:
- Article
Pharmacokinetics of primary oxidative metabolites of thalidomide in rats and in chimeric mice humanized with different human hepatocytes.
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- Journal of Toxicological Sciences, 2021, v. 46, n. 7, p. 311, doi. 10.2131/jts.46.311
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- Publication type:
- Article
Indication of intravaginal insemination for infertility treatment in couples with sexual dysfunction.
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- Reproductive Medicine & Biology, 2021, v. 20, n. 2, p. 241, doi. 10.1002/rmb2.12376
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- Publication type:
- Article
Prediabetes, Diabetes, and the Risk of All-Cause and Cause-Specific Mortality in a Japanese Working Population: Japan Epidemiology Collaboration on Occupational Health Study.
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- 2021
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- Publication type:
- journal article
Pharmacokinetics of duloxetine self-administered in overdose with quetiapine and other antipsychotic drugs in a Japanese patient admitted to hospital.
- Published in:
- Journal of Pharmaceutical Health Care & Sciences, 2021, v. 7, n. 1, p. 1, doi. 10.1186/s40780-021-00189-9
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- Publication type:
- Article
Smoking Cessation, Weight Gain, and the Trajectory of Estimated Risk of Coronary Heart Disease: 8-Year Follow-up From a Prospective Cohort Study.
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- 2021
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- Publication type:
- journal article
Metabolic profiles of coumarin in human plasma extrapolated from a rat data set with a simplified physiologically based pharmacokinetic model.
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- Journal of Toxicological Sciences, 2020, v. 45, n. 11, p. 695, doi. 10.2131/jts.45.695
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- Publication type:
- Article
Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital.
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- Journal of Pharmaceutical Health Care & Sciences, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40780-020-00176-6
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- Publication type:
- Article
Associations of anemia and hemoglobin with hemoglobin A1c among non‐diabetic workers in Japan.
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- Journal of Diabetes Investigation, 2020, v. 11, n. 3, p. 719, doi. 10.1111/jdi.13159
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- Publication type:
- Article
Smoking cessation after long-term sick leave due to cancer in comparison with cardiovascular disease: Japan Epidemiology Collaboration on Occupational Health Study.
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- Industrial Health, 2020, v. 58, n. 3, p. 246, doi. 10.2486/indhealth.2019-0136
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- Publication type:
- Article
BMI and Medically Certified Long-Term Sickness Absence Among Japanese Employees.
- Published in:
- 2020
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- Publication type:
- journal article
Five‐year cumulative incidence of overweight and obesity, and longitudinal change in body mass index in Japanese workers: The Japan Epidemiology Collaboration on Occupational Health Study.
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- Journal of Occupational Health, 2020, v. 62, n. 1, p. 1, doi. 10.1002/1348-9585.12095
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- Publication type:
- Article
Association between anthropometric indices of obesity and risk of cardiovascular disease in Japanese men.
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- Journal of Occupational Health, 2020, v. 62, n. 1, p. 1, doi. 10.1002/1348-9585.12098
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- Publication type:
- Article
Adult and infant pharmacokinetic profiling of dihydrocodeine using physiologically based pharmacokinetic modeling.
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- Biopharmaceutics & Drug Disposition, 2019, v. 40, n. 9, p. 350, doi. 10.1002/bdd.2209
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- Publication type:
- Article
Serum cholesterol levels preceding to suicide death in Japanese workers: a nested case-control study.
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- Acta Neuropsychiatrica, 2019, v. 31, n. 5, p. 266, doi. 10.1017/neu.2019.26
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- Publication type:
- Article
Low serum creatinine and risk of diabetes: The Japan Epidemiology Collaboration on Occupational Health Study.
- Published in:
- Journal of Diabetes Investigation, 2019, v. 10, n. 5, p. 1209, doi. 10.1111/jdi.13024
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- Publication type:
- Article
Human plasma and liver concentrations of styrene estimated by combining a simple physiologically based pharmacokinetic model with rodent data.
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- Journal of Toxicological Sciences, 2019, v. 44, n. 8, p. 543, doi. 10.2131/jts.44.543
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- Publication type:
- Article
Smoking, Smoking Cessation, and the Risk of Hearing Loss: Japan Epidemiology Collaboration on Occupational Health Study.
- Published in:
- 2019
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- Publication type:
- journal article
Expression and metabolic activity of flavin‐containing monooxygenase 1 in cynomolgus macaque kidney.
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- Journal of Medical Primatology, 2019, v. 48, n. 1, p. 51, doi. 10.1111/jmp.12385
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- Publication type:
- Article
Association of pharmacokinetic profiles of lenalidomide in human plasma simulated using pharmacokinetic data in humanized-liver mice with liver toxicity detected by human serum albumin RNA.
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- Journal of Toxicological Sciences, 2018, v. 43, n. 6, p. 369, doi. 10.2131/jts.43.369
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- Publication type:
- Article
Human plasma concentrations of trimethylamine N-oxide extrapolated using pharmacokinetic modeling based on metabolic profiles of deuterium-labeled trimethylamine in humanized-liver mice.
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- Journal of Toxicological Sciences, 2018, v. 43, n. 6, p. 387, doi. 10.2131/jts.43.387
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- Publication type:
- Article
Development and validation of risk models to predict the 7‐year risk of type 2 diabetes: The Japan Epidemiology Collaboration on Occupational Health Study.
- Published in:
- Journal of Diabetes Investigation, 2018, v. 9, n. 5, p. 1052, doi. 10.1111/jdi.12809
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- Publication type:
- Article
Correction: Development of Risk Score for Predicting 3-Year Incidence of Type 2 Diabetes: Japan Epidemiology Collaboration on Occupational Health Study.
- Published in:
- 2018
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- Publication type:
- Correction Notice
Preclinical and phase I clinical studies of KW-2450, a dual IGF-1R/IR tyrosine kinase inhibitor, in combination with lapatinib and letrozole.
- Published in:
- Therapeutic Advances in Medical Oncology, 2018, v. 10, n. 1, p. 1, doi. 10.1177/1758835918786858
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- Publication type:
- Article
Efavirenz clearances in vitro and in vivo in six cynomolgus monkeys associated with polymorphic cytochrome P450 2C9 and simulated by individual physiologically based pharmacokinetic models.
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- Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 7, p. 439, doi. 10.1002/bdd.2084
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- Publication type:
- Article
Metabolic syndrome components and diabetes incidence according to the presence or absence of impaired fasting glucose: The Japan Epidemiology Collaboration on Occupational Health Study.
- Published in:
- Journal of Epidemiology, 2017, v. 27, n. 9, p. 408, doi. 10.1016/j.je.2016.08.015
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- Publication type:
- Article
Human plasma and urinary metabolic profiles of trimethylamine and trimethylamine N-oxide extrapolated using a simple physiologically based pharmacokinetic model.
- Published in:
- Journal of Toxicological Sciences, 2017, v. 42, n. 4, p. 485, doi. 10.2131/jts.42.485
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- Publication type:
- Article
Current status of health among workers in Japan: Results from the Japan Epidemiology Collaboration on Occupational Health Study.
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- Industrial Health, 2016, v. 54, n. 6, p. 505
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- Publication type:
- Article
Physiologically based pharmacokinetic-pharmacodynamic modeling to predict concentrations and actions of sodium-dependent glucose transporter 2 inhibitor canagliflozin in human intestines and renal tubules.
- Published in:
- Biopharmaceutics & Drug Disposition, 2016, v. 37, n. 8, p. 491, doi. 10.1002/bdd.2040
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- Publication type:
- Article
Hba1c, Blood Pressure, and Lipid Control in People with Diabetes: Japan Epidemiology Collaboration on Occupational Health Study.
- Published in:
- PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159071
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- Publication type:
- Article
Identification of putative substrates for cynomolgus monkey cytochrome P450 2C8 by substrate depletion assays with 22 human P450 substrates and inhibitors.
- Published in:
- Biopharmaceutics & Drug Disposition, 2016, v. 37, n. 5, p. 310, doi. 10.1002/bdd.1998
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- Publication type:
- Article
Analysis of gene expression for microminipig liver transcriptomes using parallel long-read technology and short-read sequencing.
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- Biopharmaceutics & Drug Disposition, 2016, v. 37, n. 4, p. 220, doi. 10.1002/bdd.2007
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- Publication type:
- Article