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Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β.
Published in:
Journal of Molecular Neuroscience, 2015, v. 57, n. 4, p. 561, doi. 10.1007/s12031-015-0638-y
By:
- Hu, Shengquan;
- Cui, Wei;
- Zhang, Zaijun;
- Mak, Shinghung;
- Xu, Daping;
- Li, Gang;
- Hu, Yuanjia;
- Wang, Yuqiang;
- Lee, Mingyuen;
- Tsim, Karl;
- Han, Yifan
Publication type:
Article
Reduced Expression of P2Y2 Receptor and Acetylcholinesterase at Neuromuscular Junction of P2Y1 Receptor Knock-out Mice.
Published in:
Journal of Molecular Neuroscience, 2015, v. 57, n. 3, p. 446, doi. 10.1007/s12031-015-0591-9
By:
- Xu, Miranda;
- Bi, Cathy;
- Cheng, Lily;
- Mak, Shinghung;
- Yao, Ping;
- Luk, Wilson;
- Lau, Kitty;
- Cheng, Anthony;
- Tsim, Karl
Publication type:
Article
Inhibiting β-Amyloid-Associated Alzheimer's Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue.
Published in:
Journal of Molecular Neuroscience, 2015, v. 55, n. 4, p. 1014, doi. 10.1007/s12031-014-0458-5
By:
- Hu, Shengquan;
- Wang, Rui;
- Cui, Wei;
- Zhang, Zaijun;
- Mak, Shinghung;
- Xu, Daping;
- Choi, Chunglit;
- Tsim, Karl;
- Carlier, Paul;
- Lee, Mingyuen;
- Han, Yifan
Publication type:
Article
Synergistic Inhibition on Acetylcholinesterase by the Combination of Berberine and Palmatine Originally Isolated from Chinese Medicinal Herbs.
Published in:
Journal of Molecular Neuroscience, 2014, v. 53, n. 3, p. 511, doi. 10.1007/s12031-014-0288-5
By:
- Mak, Shinghung;
- Luk, Wilson;
- Cui, Wei;
- Hu, Shengquan;
- Tsim, Karl;
- Han, Yifan
Publication type:
Article
Unexpected Neuronal Protection of SU5416 against 1-Methyl-4-Phenylpyridinium Ion-Induced Toxicity via Inhibiting Neuronal Nitric Oxide Synthase.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046253
By:
- Wei Cui;
- Zaijun Zhang;
- Wenming Li;
- Shinghung Mak;
- Shengquan Hu;
- Huan Zhang;
- Shuai Yuan;
- Jianhui Rong;
- Choi, Tony Chunglit;
- Lee, Simon M. Y.;
- Yifan Han;
- Vitorica, Javier
Publication type:
Article
Promising tacrine/huperzine A‐based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget.
Published in:
Journal of Neurochemistry, 2021, v. 158, n. 6, p. 1381, doi. 10.1111/jnc.15379
By:
- Mak, Shinghung;
- Li, Wenming;
- Fu, Hongjun;
- Luo, Jialie;
- Cui, Wei;
- Hu, Shengquan;
- Pang, Yuanping;
- Carlier, Paul R.;
- Tsim, Karl Wahkeung;
- Pi, Rongbiao;
- Han, Yifan
Publication type:
Article
Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice.
Published in:
Frontiers in Cellular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fncel.2018.00396
By:
- Chen, Huixin;
- Wu, Xiang;
- Gu, Xinmei;
- Zhou, Yiying;
- Ye, Luying;
- Zhang, Ke;
- Pan, Hanbo;
- Wang, Jialing;
- Wei, Hua;
- Zhu, Binbin;
- Naman, C. Benjamin;
- Mak, Shinghung;
- Carlier, Paul R.;
- Cui, Wei;
- Han, Yifan
Publication type:
Article
Potent Protection Against MPP-Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine.
Published in:
NeuroMolecular Medicine, 2016, v. 18, n. 4, p. 561, doi. 10.1007/s12017-016-8399-5
By:
- Hu, Shengquan;
- Wang, Liang;
- Mak, Shinghung;
- Zhang, Zaijun;
- Xu, Daping;
- Li, Haitao;
- Li, Yide;
- Hu, Yuanjia;
- Lee, Simon;
- Wang, Yuqiang;
- Han, Yifan
Publication type:
Article
Regulation of acetylcholinesterase during the lipopolysaccharide‐induced inflammatory responses in microglial cells.
Published in:
FASEB Journal, 2022, v. 36, n. 3, p. 1, doi. 10.1096/fj.202101302RR
By:
- Xia, Yingjie;
- Wu, Qiyun;
- Mak, Shinghung;
- Liu, Etta Y. L.;
- Zheng, Brody Z. Y.;
- Dong, Tina T. X.;
- Pi, Rongbiao;
- Tsim, Karl W. K.
Publication type:
Article
Neuroprotection Against MPP<sup>+</sup>-Induced Cytotoxicity Through the Activation of PI3-K/Akt/GSK3β/MEF2D Signaling Pathway by Rhynchophylline, the Major Tetracyclic Oxindole Alkaloid Isolated From Uncaria rhynchophylla.
Published in:
Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00768
By:
- Shengquan Hu;
- Shinghung Mak;
- Xialin Zuo;
- Haitao Li;
- Yuqiang Wang;
- Yifan Han
Publication type:
Article
The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models.
Published in:
2019
By:
- Luo, Fangcheng;
- Wu, Liangmiao;
- Zhang, Zhixiang;
- Zhu, Zeyu;
- Liu, Zheng;
- Guo, Baojian;
- Li, Ning;
- Ju, Jun;
- Zhou, Qiang;
- Li, Shupeng;
- Yang, Xifei;
- Mak, Shinghung;
- Han, Yifan;
- Sun, Yewei;
- Wang, Yuqiang;
- Zhang, Gaoxiao;
- Zhang, Zaijun
Publication type:
journal article
Indirubin-3-Oxime Prevents HO-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway.
Published in:
Cellular & Molecular Neurobiology, 2017, v. 37, n. 4, p. 655, doi. 10.1007/s10571-016-0402-z
By:
- Yu, Jie;
- Zheng, Jiacheng;
- Lin, Jiajia;
- Jin, Linlu;
- Yu, Rui;
- Mak, Shinghung;
- Hu, Shengquan;
- Sun, Hongya;
- Wu, Xiang;
- Zhang, Zaijun;
- Lee, Mingyuen;
- Tsim, Wahkeung;
- Su, Wei;
- Zhou, Wenhua;
- Cui, Wei;
- Han, Yifan;
- Wang, Qinwen
Publication type:
Article
Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin.
Published in:
Scientific Reports, 2015, p. 10256, doi. 10.1038/srep10256
By:
- Chang, Lan;
- Yang, Yong;
- Xu, Shujun;
- Zhou, Wenhua;
- Hu, Juwei;
- Wang, Qinwen;
- Cui, Wei;
- Fu, Hongjun;
- Hu, Shengquan;
- Mak, Shinghung;
- Chung-lit Choi, Tony;
- Han, Yifan;
- Wang, Qin;
- Tao, Liang;
- Pui-Yan Ma, Victor;
- Dik-lung Ma, Edmond;
- Pang, Yuanping;
- Rowan, Michael J.;
- Anwyl, Roger
Publication type:
Article
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor.
Published in:
Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00073
By:
- Hu, Shengquan;
- Hu, Huihui;
- Mak, Shinghung;
- Cui, Guozhen;
- Lee, Mingyuen;
- Shan, Luchen;
- Wang, Yuqiang;
- Lin, Huangquan;
- Zhang, Zaijun;
- Han, Yifan
Publication type:
Article
The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Published in:
2013
By:
- Cui, Wei;
- Zhang, Zaijun;
- Li, Wenming;
- Hu, Shengquan;
- Mak, Shinghung;
- Zhang, Huan;
- Han, Renwen;
- Yuan, Shuai;
- Li, Sai;
- Sa, Fei;
- Xu, Daping;
- Lin, Zhixiu;
- Zuo, Zhong;
- Rong, Jianhui;
- Ma, Edmond Dik-Lung;
- Choi, Tony Chunglit;
- Lee, Simon My;
- Han, Yifan
Publication type:
journal article
The anti-cancer agent SU4312 unexpectedly protects against MPP<sup>+</sup>-induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Published in:
British Journal of Pharmacology, 2013, v. 168, n. 5, p. 1201, doi. 10.1111/bph.12004
By:
- Cui, Wei;
- Zhang, Zaijun;
- Li, Wenming;
- Hu, Shengquan;
- Mak, Shinghung;
- Zhang, Huan;
- Han, Renwen;
- Yuan, Shuai;
- Li, Sai;
- Sa, Fei;
- Xu, Daping;
- Lin, Zhixiu;
- Zuo, Zhong;
- Rong, Jianhui;
- Ma, Edmond Dik ‐ Lung;
- Choi, Tony Chunglit;
- Lee, Simon MY;
- Han, Yifan
Publication type:
Article

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