Works by Major, Michael B.

Results: 27

STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.

Published in:

Advanced Science, 2023, v. 10, n. 3, p. 1, doi. 10.1002/advs.202203718

By:

Zhu, Zhichuan;
Zhou, Xin;
Du, Hongwei;
Cloer, Erica W.;
Zhang, Jiaming;
Mei, Liu;
Wang, Ying;
Tan, Xianming;
Hepperla, Austin J.;
Simon, Jeremy M.;
Cook, Jeanette Gowen;
Major, Michael B.;
Dotti, Gianpietro;
Liu, Pengda

Publication type:

Article

FAM123A Binds to Microtubules and Inhibits the Guanine Nucleotide Exchange Factor ARHGEF2 to Decrease Actomyosin Contractility.

Published in:

Science Signaling, 2012, v. 5, n. 240, p. 1, doi. 10.1126/scisignal.2002871

By:

Siesser, Priscila F.;
Motolese, Marta;
Walker, Matthew P.;
Goldfarb, Dennis;
Gewain, Kelly;
Yan, Feng;
Kulikauskas, Rima M.;
Chien, Andy J.;
Wordeman, Linda;
Major, Michael B.

Publication type:

Article

Bruton's Tyrosine Kinase Revealed as a Negative Regulator of Wnt-β-Catenin Signaling.

Published in:

Science Signaling, 2009, v. 2, n. 72, p. 1, doi. 10.1126/scisignal.2000230

By:

James, Richard G.;
Biechele, Travis L.;
Conrad, William H.;
Camp, Nathan D.;
Fass, Daniel M.;
Major, Michael B.;
Sommer, Karen;
Yi, XianHua;
Roberts, Brian S.;
Cleary, Michele A.;
Arthur, William T.;
MacCoss, Michael;
Rawlings, David J.;
Haggarty, Stephen J.;
Moon, Randall T.

Publication type:

Article

"Omic" Risk Assessment.

Published in:

Science Signaling, 2009, v. 2, n. 72, p. 1, doi. 10.1126/scisignal.272eg7

By:

Major, Michael B.;
Moon, Randall T.

Publication type:

Article

Integrative Analysis of Genome-Wide RNA Interference Screens.

Published in:

Science Signaling, 2009, v. 2, n. 70, p. 1, doi. 10.1126/scisignal.270pt4

By:

Berndt, Jason D.;
Biechele, Travis L.;
Moon, Randall T.;
Major, Michael B.

Publication type:

Article

New Regulators of Wnt/β-Catenin Signaling Revealed by Integrative Molecular Screening.

Published in:

Science Signaling, 2008, v. 1, n. 45, p. 1, doi. 10.1126/scisignal.2000037

By:

Major, Michael B.;
Roberts, Brian S.;
Berndt, Jason D.;
Marine, Shane;
Anastas, Jamie;
Chung, Namjin;
Ferrer, Marc;
XianHua Yi;
Stoick-Cooper, Cristi L.;
Haller, Priska D. von;
Kategaya, Lorna;
Chien, Andy;
Angers, Stephane;
MacCoss, Michael;
Cleary, Michele A.;
Arthur, William T.;
Moon, Randall T.

Publication type:

Article

ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas.

Published in:

PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0297741

By:

Nguyen, Vinh;
Schrank, Travis P.;
Major, Michael B.;
Weissman, Bernard E.

Publication type:

Article

Engineering a genetically encoded competitive inhibitor of the KEAP1–NRF2 interaction via structure-based design and phage display.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 1, p. 1, doi. 10.1093/protein/gzv055

By:

Guntas, Gurkan;
Lewis, Steven M.;
Mulvaney, Kathleen M.;
Cloer, Erica W.;
Tripathy, Ashutosh;
Lane, Thomas R.;
Major, Michael B.;
Kuhlman, Brian

Publication type:

Article

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.

Published in:

Journal of Pathology, 2020, v. 252, n. 2, p. 125, doi. 10.1002/path.5504

By:

Bowman, Brittany M;
Montgomery, Stephanie A;
Schrank, Travis P;
Simon, Jeremy M;
Ptacek, Travis S;
Tamir, Tigist Y;
Mulvaney, Kathleen M;
Weir, Seth J;
Nguyen, Tuong T;
Murphy, Ryan M;
Makowski, Liza;
Hayes, D Neil;
Chen, Xiaoxin L;
Randell, Scott H;
Weissman, Bernard E;
Major, Michael B

Publication type:

Article

Weight loss reduces basal-like breast cancer through kinome reprogramming.

Published in:

Cancer Cell International, 2016, v. 16, p. 1, doi. 10.1186/s12935-016-0300-y

By:

Yuanyuan Qin;
Sundaram, Sneha;
Essaid, Luma;
Xin Chen;
Miller, Samantha M.;
Feng Yan;
Darr, David B.;
Galanko, Joseph A.;
Montgomery, Stephanie A.;
Major, Michael B.;
Johnson, Gary L.;
Troester, Melissa A.;
Makowski, Liza

Publication type:

Article

Glycosylation of KEAP1 links nutrient sensing to redox stress signaling.

Published in:

EMBO Journal, 2017, v. 36, n. 15, p. 2233, doi. 10.15252/embj.201696113

By:

Chen, Po‐Han;
Smith, Timothy J;
Wu, Jianli;
Siesser, Priscila F;
Bisnett, Brittany J;
Khan, Farhan;
Hogue, Maxwell;
Soderblom, Erik;
Tang, Flora;
Marks, Jeffrey R;
Major, Michael B;
Swarts, Benjamin M;
Boyce, Michael;
Chi, Jen‐Tsan

Publication type:

Article

Author Correction: A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

Published in:

2024

By:

Gao, Yanzhe;
Mutter-Rottmayer, Elizabeth;
Greenwalt, Alicia M.;
Goldfarb, Dennis;
Yan, Feng;
Yang, Yang;
Martinez-Chacin, Raquel C.;
Pearce, Kenneth H.;
Tateishi, Satoshi;
Major, Michael B.;
Vaziri, Cyrus

Publication type:

Correction Notice

A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52803-7

By:

Puray-Chavez, Maritza;
Eschbach, Jenna E.;
Xia, Ming;
LaPak, Kyle M.;
Zhou, Qianzi;
Jasuja, Ria;
Pan, Jiehong;
Xu, Jian;
Zhou, Zixiang;
Mohammed, Shawn;
Wang, Qibo;
Lawson, Dana Q.;
Djokic, Sanja;
Hou, Gaopeng;
Ding, Siyuan;
Brody, Steven L.;
Major, Michael B.;
Goldfarb, Dennis;
Kutluay, Sebla B.

Publication type:

Article

The mucolipidosis IV Ca<sup>2+</sup> channel TRPML1 (MCOLN1) is regulated by the TOR kinase.

Published in:

Biochemical Journal, 2015, v. 470, n. 3, p. 331, doi. 10.1042/BJ20150219

By:

Onyenwoke, Rob U.;
Sexton, Jonathan Z.;
Feng Yan;
Huertas Díaz, María Cristina;
Forsberg, Lawrence J.;
Major, Michael B.;
Brenman, Jay E.

Publication type:

Article

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.

Published in:

PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0174863

By:

Stratford, Jeran K.;
Graves, Lee M.;
Der, Channing J.;
Yeh, Jen Jen;
Hill, Rebecca A.;
Major, Michael B.;
Yan, Feng

Publication type:

Article

A 1,536-Well Ultra-High-Throughput siRNA Screen to Identify Regulators of the Wnt/β-Catenin Pathway.

Published in:

Assay & Drug Development Technologies, 2010, v. 8, n. 3, p. 286, doi. 10.1089/adt.2009.0262

By:

Namjin Chung;
Shane Marine;
Emily A. Smith;
Robert Liehr;
S. Todd Smith;
Louis Locco;
Edward Hudak;
Anthony Kreamer;
Alison Rush;
Brian Roberts;
Michael B. Major;
Randall T. Moon;
William Arthur;
Michele Cleary;
Berta Strulovici;
Marc Ferrer

Publication type:

Article

MSAcquisitionSimulator: data-dependent acquisition simulator for LC-MS shotgun proteomics.

Published in:

Bioinformatics, 2016, v. 32, n. 8, p. 1269, doi. 10.1093/bioinformatics/btv745

By:

Goldfarb, Dennis;
Wei Wang;
Major, Michael B.

Publication type:

Article

The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33601-w

By:

Gao, Yanzhe;
Kardos, Jordan;
Yang, Yang;
Tamir, Tigist Y.;
Mutter-Rottmayer, Elizabeth;
Weissman, Bernard;
Major, Michael B.;
Kim, William Y.;
Vaziri, Cyrus

Publication type:

Article

Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 17, p. 9415, doi. 10.1093/nar/gkaa544

By:

Skrajna, Aleksandra;
Goldfarb, Dennis;
Kedziora, Katarzyna M;
Cousins, Emily M;
Grant, Gavin D;
Spangler, Cathy J;
Barbour, Emily H;
Yan, Xiaokang;
Hathaway, Nathaniel A;
Brown, Nicholas G;
Cook, Jeanette G;
Major, Michael B;
McGinty, Robert K

Publication type:

Article

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

Published in:

Nature Communications, 2016, v. 7, n. 7, p. 12105, doi. 10.1038/ncomms12105

By:

Gao, Yanzhe;
Mutter-Rottmayer, Elizabeth;
Greenwalt, Alicia M.;
Goldfarb, Dennis;
Yan, Feng;
Yang, Yang;
Martinez-Chacin, Raquel C.;
Pearce, Kenneth H.;
Tateishi, Satoshi;
Major, Michael B.;
Vaziri, Cyrus

Publication type:

Article

FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma.

Published in:

Science Signaling, 2015, v. 8, n. 362, p. 1, doi. 10.1126/scisignal.2005654

By:

Walker, Matthew P.;
Rabinowitz, Alex D.;
Graham, David M.;
Feng Yan;
Major, Michael B.;
Stopford, Charles M.;
Damania, Blossom;
Cederlund, Maria;
Jahn, Christopher;
Weidinger, Gilbert;
Fang Fang;
Davis, Ian J.;
Goldfarb, Dennis;
Deal, Allison M.;
Fedoriw, Yuri;
Richards, Kristy L.

Publication type:

Article

Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening.

Published in:

Integrative Biology, 2014, v. 6, n. 7, p. 673, doi. 10.1039/c4ib00050a

By:

Shah, Pavak K.;
Walker, Matthew P.;
Sims, Christopher E.;
Major, Michael B.;
Allbritton, Nancy L.

Publication type:

Article

WIKI4, a Novel Inhibitor of Tankyrase and Wnt/ß-Catenin Signaling.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050457

By:

James, Richard G.;
Davidson, Kathryn C.;
Bosch, Katherine A.;
Biechele, Travis L.;
Robin, Nicholas C.;
Taylor, Russell J.;
Major, Michael B.;
Camp, Nathan D.;
Fowler, Kerry;
Martins, Timothy J.;
Moon, Randall T.

Publication type:

Article

Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p53.

Published in:

PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002922

By:

Sorrells, Shelly;
Carbonneau, Seth;
Harrington, Erik;
Chen, Aye T.;
Hast, Bridgid;
Milash, Brett;
Pyati, Ujwal;
Major, Michael B.;
Yi Zhou;
Zon, Leonard I.;
Stewart, Rodney A.;
Look, A. Thomas;
Jette, Cicely

Publication type:

Article

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.17101

By:

Harrison, Joseph S.;
Cornett, Evan M.;
Goldfarb, Dennis;
DaRosa, Paul A.;
Li, Zimeng M.;
Feng Yan;
Dickson, Bradley M.;
Guo, Angela H.;
Cantu, Daniel V.;
Kaustov, Lilia;
Brown, Peter J.;
Arrowsmith, Cheryl H.;
Erie, Dorothy A.;
Major, Michael B.;
Klevit, Rachel E.;
Krajewski, Krzysztof;
Kuhlman, Brian;
Strahl, Brian D.;
Rothbart, Scott B.

Publication type:

Article

Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 19, p. 11536, doi. 10.1093/nar/gkae761

By:

Chen, Jianfeng;
Su, Siyuan;
Pickar-Oliver, Adrian;
Chiarella, Anna M;
Hahn, Quentin;
Goldfarb, Dennis;
Cloer, Erica W;
Small, George W;
Sivashankar, Smaran;
Ramsden, Dale A;
Major, Michael B;
Hathaway, Nathaniel A;
Gersbach, Charles A;
Liu, Pengda

Publication type:

Article

The MyMOMA domain of MYO19 encodes for distinct Miro‐dependent and Miro‐independent mechanisms of interaction with mitochondrial membranes.

Published in:

Cytoskeleton, 2020, v. 77, n. 3/4, p. 149, doi. 10.1002/cm.21560

By:

Bocanegra, Jennifer L.;
Fujita, Barbara M.;
Melton, Natalie R.;
Cowan, James M.;
Schinski, Elizabeth L.;
Tamir, Tigist Y.;
Major, Michael B.;
Quintero, Omar A.

Publication type:

Article