Works matching AU Main, Leighanne R

Results: 25
    1

    Examination of MGMT as a risk gene for dementia in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 1, p. 1, doi. 10.1002/alz.14356
    By:
    • Main, Leighanne R.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Laux, Renee A.;
    • Miskimen, Kristy L.;
    • Osterman, Michael D.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Dorfsman, Daniel A.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Adams, Larry D.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Scott, William K.
    Publication type:
    Article
    2

    Biomarker‐guided clustering in an Amish population older than 60 reveals subgroups featuring distinct Alzheimer Disease pathologies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.089004
    By:
    • Wang, Ping;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Miskimen, Kristy L.;
    • Prough, Michael B.;
    • Dorfsman, Daniel A.;
    • Gulyayev, Alex V.;
    • Laux, Renee A.;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Zaman, Andrew F;
    • Adams, Larry D.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Whitehead, Patrice L.;
    • Liu, Yining;
    • Moore, Noel C.;
    • Main, Leighanne R.;
    • Ogrocki, Paula K.
    Publication type:
    Article
    3

    Linkage and Haplotype Association of Cognitive SuperAging to Chromosome 14 in the Midwestern Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.090963
    By:
    • Dorfsman, Daniel A.;
    • Prough, Michael B.;
    • Gulyayev, Alex V.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R.;
    • Wang, Ping;
    • Liu, Yining;
    • Moore, Noel C.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.
    Publication type:
    Article
    4

    Mosaic Loss of Chromosome Y in Peripheral Blood Cells from Whole‐Genome Sequencing and Alzheimer's Disease in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.089681
    By:
    • Song, Yeunjoo E.;
    • Laux, Renee A.;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Miskimen, Kristy L.;
    • Lynn, Audrey;
    • Wang, Weihuan;
    • Main, Leighanne R.;
    • Wang, Ping;
    • Liu, Yining;
    • Moore, Noel C.;
    • Prough, Michael B.;
    • Dorfsman, Daniel A.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Gulyayev, Alex V.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Vance, Jeffery M.
    Publication type:
    Article
    5

    Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 11, p. 7453, doi. 10.1002/alz.14045
    By:
    • Main, Leighanne R.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Laux, Renee A.;
    • Miskimen, Kristy L.;
    • Osterman, Michael D.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Dorfsman, Daniel A.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Adams, Larry D.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Scott, William K.
    Publication type:
    Article
    6

    Detecting Protective Rare Variants for Alzheimer's Disease from Whole‐Genome Sequencing in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080040
    By:
    • Song, Yeunjoo E.;
    • Wang, Weihuan;
    • Miskimen, Kristy L.;
    • Laux, Renee A.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Main, Leighanne R.;
    • Osterman, Michael D.;
    • Lynn, Audrey;
    • Prough, Michael B.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Dorfsman, Daniel A.;
    • Vance, Jeffery M.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.
    Publication type:
    Article
    7

    The Genetics of Cognitive Resistance and Resilience in the Ohio and Indiana Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071640
    By:
    • Main, Leighanne R.;
    • Song, Yeunjoo E.;
    • Laux, Renee A.;
    • Miskimen, Kristy L.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Osterman, Michael D.;
    • Lynn, Audrey;
    • Dorfsman, Daniel A.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Adams, Larry D.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Scott, William K.
    Publication type:
    Article
    8

    Detecting Protective Rare Variants for Alzheimer's Disease from Whole‐Genome Sequencing in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080040
    By:
    • Song, Yeunjoo E.;
    • Wang, Weihuan;
    • Miskimen, Kristy L.;
    • Laux, Renee A.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Main, Leighanne R.;
    • Osterman, Michael D.;
    • Lynn, Audrey;
    • Prough, Michael B.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Dorfsman, Daniel A.;
    • Vance, Jeffery M.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.
    Publication type:
    Article
    9

    The Genetics of Cognitive Resistance and Resilience in the Ohio and Indiana Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071640
    By:
    • Main, Leighanne R.;
    • Song, Yeunjoo E.;
    • Laux, Renee A.;
    • Miskimen, Kristy L.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Osterman, Michael D.;
    • Lynn, Audrey;
    • Dorfsman, Daniel A.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Adams, Larry D.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Scott, William K.
    Publication type:
    Article
    10

    Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 2, p. 611, doi. 10.1002/alz.12686
    By:
    • Ramos, Jairo;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R.;
    • Osterman, Michael D.;
    • Zaman, Andrew F.;
    • Whitehead, Patrice L.;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Song, Yeunjoo E.;
    • Foroud, Tatiana M.;
    • Mayeux, Richard P.;
    • St. George‐Hyslop, Peter
    Publication type:
    Article
    11

    Plasma pTau181 is associated with impaired cognition in the Old Order Amish and adds additional information beyond the known genetic risk factors for AD.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.067752
    By:
    • Prough, Michael B.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Dorfsman, Daniel A.;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Miller, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R.;
    • Osterman, Michael D.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Cuccaro, Michael L.
    Publication type:
    Article
    12

    Mosaic Loss of Chromosome Y in Peripheral Blood Cells and Cognitive Status in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.068167
    By:
    • Song, Yeunjoo E.;
    • Miskimen, Kristy L.;
    • Laux, Renee A.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Miller, Sherri D.;
    • Main, Leighanne R.;
    • Osterman, Michael D.;
    • Lynn, Audrey;
    • Prough, Michael B.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Dorfsman, Daniel A.;
    • Vance, Jeffery M.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.
    Publication type:
    Article
    13

    Association of mitochondrial haplogroups and cognitive impairment in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067658
    By:
    • Dorfsman, Daniel A.;
    • Prough, Michael B.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R.;
    • Osterman, Michael D.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Cuccaro, Michael L.
    Publication type:
    Article
    14

    Assessing a Network‐Specific Polygenic Risk Score for Alzheimer's Disease in the Midwestern Amish and Across Diverse Ancestries.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067210
    By:
    • Osterman, Michael D.;
    • Song, Yeunjoo E.;
    • Wheeler, Nicholas R.;
    • Laux, Renee A.;
    • Adams, Larry D.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Lynn, Audrey;
    • Bartlett, Jacquelaine;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R.;
    • Dorfsman, Daniel A.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.
    Publication type:
    Article
    15

    Detecting genetic loci for preservation of cognition in the Midwestern United States Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.061554
    By:
    • Main, Leighanne R.;
    • Song, Yeunjoo E.;
    • Laux, Renee A.;
    • Miskimen, Kristy L.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Hochstetler, Sherri D.;
    • Osterman, Michael D.;
    • Lynn, Audrey;
    • Dorfsman, Daniel A.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Adams, Larry D.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Scott, William K.
    Publication type:
    Article
    16

    Genome‐wide association study of cognitive status and decline in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056525
    By:
    • Song, Yeunjoo E.;
    • Main, Leighanne R;
    • Miskimen, Kristy L.;
    • Laux, Renee A.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Miller, Sherri D.;
    • Sewell, Jane L.;
    • Osterman, Michael D.;
    • Lynn, Audrey;
    • Prough, Michael B.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Ramos, Jairo;
    • Dorfsman, Daniel A.;
    • Vance, Jeffery M.;
    • Cuccaro, Michael L.
    Publication type:
    Article
    17

    Genome‐wide association for protective variants in Alzheimer's disease in the Midwestern Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056363
    By:
    • Main, Leighanne R;
    • Song, Yeunjoo E.;
    • Laux, Renee A.;
    • Miskimen, Kristy L.;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Sewell, Jane L.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Adams, Larry D.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Scott, William K.;
    • Pericak‐Vance, Margaret A.;
    • Haines, Jonathan L.
    Publication type:
    Article
    18

    Preferential preservation of constructional praxis delayed recall compared to word list delayed recall in the Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056386
    By:
    • Prough, Michael B.;
    • Caywood, Laura J.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Dorfsman, Daniel A.;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Sewell, Jane L.;
    • Miller, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R;
    • Osterman, Michael D.;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Ramos, Jairo
    Publication type:
    Article
    19

    Suggestive linkage and association of preserved cognition to chromosome 18 in genetically at‐risk Amish.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056306
    By:
    • Dorfsman, Daniel A.;
    • Prough, Michael B.;
    • Caywood, Laura J.;
    • Close, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Sewell, Jane L.;
    • Miller, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R;
    • Osterman, Michael D.;
    • Fuzzell, Sarada L.;
    • Fuzzell, M. Denise;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Ramos, Jairo
    Publication type:
    Article
    20

    Association of a locus on chromosome 17 with earlier age at onset of cognitive impairment in a familial Amish dataset.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056288
    By:
    • Scott, William K.;
    • Ramos, Jairo;
    • Slifer, Susan H.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Clouse, Jason E.;
    • Dorfsman, Daniel A.;
    • Herington, Sharlene D.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Sewell, Jane L.;
    • Miller, Sherri D.;
    • Osterman, Michael D.;
    • Main, Leighanne R;
    • Miskimen, Kristy L.;
    • Lynn, Audrey;
    • Whitehead, Patrice L.;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Song, Yeunjoo E.
    Publication type:
    Article
    21

    Genetic risk score for Alzheimer's disease in the Amish highlights differences in the genetic architecture compared to other European ancestry populations.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053304
    By:
    • Osterman, Michael D.;
    • Song, Yeunjoo E.;
    • Lynn, Audrey;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Caywood, Laura J.;
    • Prough, Michael B.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Fuzzell, M Denise;
    • Fuzzell, Sarada L.;
    • Sewell, Jane L.;
    • Miller, Sherri D.;
    • Miskimen, Kristy L.;
    • Main, Leighanne R;
    • Ogrocki, Paula K.;
    • Lerner, Alan J.;
    • Ramos, Jairo;
    • Vance, Jeffery M.
    Publication type:
    Article
    22

    Joint linkage and association mapping of preserved cognition in the old‐order Amish: Genetics/genetics of cognitive aging.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046416
    By:
    • Ramos, Jairo;
    • Jaworski, James;
    • Adams, Larry D.;
    • Laux, Renee A.;
    • Caywood, Laura J.;
    • Prough, Michael;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Slifer, Susan H.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Sewell, Jane L.;
    • Miller, Sherri D.;
    • Song, Yeunjoo E.;
    • Miskimen, Kristy;
    • Main, Leighanne R.;
    • Ogrocki, Paula;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Cuccaro, Michael L.
    Publication type:
    Article
    23

    Search for protective genetic variants in Alzheimer disease in the U.S. Midwestern Amish: Genetics/genetic factors of Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045350
    By:
    • Main, Leighanne R.;
    • Song, Yeunjoo E.;
    • Laux, Renee A.;
    • Miskimen, Kristy;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, M. Denise;
    • Fuzzell, Sarada L.;
    • Sewell, Jane L.;
    • Lynn, Audrey;
    • Caywood, Laura J.;
    • Prough, Michael;
    • Scott, Bill;
    • Adams, Larry D.;
    • Clouse, Jason E.;
    • Herington, Sharlene D.;
    • Pericak‐Vance, Margaret A.;
    • Haines, Jonathan L.
    Publication type:
    Article
    24

    P3‐135: PROTECTIVE GENETIC VARIANTS IN THE MIDWESTERN AMISH.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P982, doi. 10.1016/j.jalz.2019.06.3163
    By:
    • Main, Leighanne R.;
    • Disher, Michelle C.;
    • Song, Yeunjoo;
    • Laux, Renee;
    • Miskimen, Kristy;
    • Cuccaro, Michael L.;
    • Ogrocki, Paula;
    • Lerner, Alan J.;
    • Vance, Jeffery M.;
    • Fuzzell, M Denise;
    • Fuzzell, Sarada;
    • Sewell, Jane;
    • Caywood, Laura J.;
    • Prough, Michael;
    • Scott, Bill;
    • Pericak-Vance, Margaret A.;
    • Haines, Jonathan L.
    Publication type:
    Article
    25