Works by Maher, Pamela

Results: 80

Affinity‐Based Protein Profiling Reveals IDH2 as a Mitochondrial Target of Cannabinol in Receptor‐Independent Neuroprotection.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 33, p. 1, doi. 10.1002/chem.202501143

By:

Schaller, Eva;
Lamer, Stephanie;
Schlosser, Andreas;
Stigloher, Christian;
Maher, Pamela;
Decker, Michael

Publication type:

Article

Sterubin: Enantioresolution and Configurational Stability, Enantiomeric Purity in Nature, and Neuroprotective Activity in Vitro and in Vivo.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 32, p. 7299, doi. 10.1002/chem.202001264

By:

Hofmann, Julian;
Fayez, Shaimaa;
Scheiner, Matthias;
Hoffmann, Matthias;
Oerter, Sabrina;
Appelt‐Menzel, Antje;
Maher, Pamela;
Maurice, Tangui;
Bringmann, Gerhard;
Decker, Michael

Publication type:

Article

Effect of fibroblast growth factor saporin mitotoxins on human bladder cell lines.

Published in:

Clinical & Experimental Metastasis, 1997, v. 15, n. 6, p. 620, doi. 10.1023/A:1018443430904

By:

Tetzke, Tamara;
Caton, Maureen;
Maher, Pamela;
Parandoosh, Zahra

Publication type:

Article

Regulation of xCT expression and system function in neuronal cells.

Published in:

Amino Acids, 2012, v. 42, n. 1, p. 171, doi. 10.1007/s00726-011-0862-x

By:

Lewerenz, Jan;
Maher, Pamela;
Methner, Axel

Publication type:

Article

A Potential Role for the Amyloid Precursor Protein in the Regulation of Interferon Signaling, Cholesterol Homeostasis, and Tau Phosphorylation in Niemann–Pick Disease Type C.

Published in:

Genes, 2024, v. 15, n. 8, p. 1066, doi. 10.3390/genes15081066

By:

Sanchez, Kayla L.;
Shin, Samuel D.;
Rajagopal, Naren P.;
White, Jacob B.;
Currais, Antonio;
Soriano-Castell, David;
Maher, Pamela;
Soriano, Salvador

Publication type:

Article

Differential Interferon Signaling Regulation and Oxidative Stress Responses in the Cerebral Cortex and Cerebellum Could Account for the Spatiotemporal Pattern of Neurodegeneration in Niemann–Pick Disease Type C.

Published in:

Genes, 2024, v. 15, n. 1, p. 101, doi. 10.3390/genes15010101

By:

Tolan, Andrew J.;
Sanchez, Kayla L.;
Shin, Samuel D.;
White, Jacob B.;
Currais, Antonio;
Soriano-Castell, David;
Wilson, Christopher G.;
Maher, Pamela;
Soriano, Salvador

Publication type:

Article

Hyperosmotic Stress Initiates AMPK-Independent Autophagy and AMPK- and Autophagy-Independent Depletion of Thioredoxin 1 and Glyoxalase 2 in HT22 Nerve Cells.

Published in:

Oxidative Medicine & Cellular Longevity, 2019, p. 1, doi. 10.1155/2019/2715810

By:

Dafre, Alcir Luiz;
Schmitz, Ariana Ern;
Maher, Pamela

Publication type:

Article

Evidence of Oxytosis/Ferroptosis in Niemann–Pick Disease Type C.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 7, p. 2915, doi. 10.3390/ijms26072915

By:

Sanchez, Kayla L.;
Kim, Jeanyoung;
White, Jacob B.;
Tolan, Andrew;
Rajagopal, Naren P.;
Anderson, Douglas W.;
Shin, Alexandra N.;
Shin, Samuel D.;
Currais, Antonio;
Soriano-Castell, David;
Maher, Pamela;
Soriano, Salvador

Publication type:

Article

Attenuation of Age-Related Hearing Impairment in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice Treated with Fatty Acid Synthase Inhibitor CMS121.

Published in:

Journal of Molecular Neuroscience, 2023, v. 73, n. 4/5, p. 307, doi. 10.1007/s12031-023-02119-w

By:

Pham, Tammy B.;
Boussaty, Ely Cheikh;
Currais, Antonio;
Maher, Pamela;
Schubert, David R.;
Manor, Uri;
Friedman, Rick A.

Publication type:

Article

A chemical biology approach to identifying molecular pathways associated with aging.

Published in:

GeroScience, 2021, v. 43, n. 1, p. 353, doi. 10.1007/s11357-020-00238-5

By:

Currais, Antonio;
Huang, Ling;
Petrascheck, Michael;
Maher, Pamela;
Schubert, David

Publication type:

Article

A structural comparison of salt forms of dopamine with the structures of other phenylethylamines.

Published in:

Acta Crystallographica Section C: Structural Chemistry, 2023, v. 79, n. 10, p. 386, doi. 10.1107/S2053229623007696

By:

Kennedy, Alan R.;
Cruickshank, Laura;
Maher, Pamela;
McKinnon, Zoe

Publication type:

Article

Neuroimmunology of the Interleukins 13 and 4.

Published in:

Brain Sciences (2076-3425), 2016, v. 6, n. 2, p. 18, doi. 10.3390/brainsci6020018

By:

Mori, Simone;
Conti, Bruno;
Maher, Pamela

Publication type:

Article

A Novel Neurotrophic Drug for Cognitive Enhancement and Alzheimer's Disease.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0027865

By:

Chen, Qi;
Prior, Marguerite;
Dargusch, Richard;
Roberts, Amanda;
Riek, Roland;
Eichmann, Cédric;
Chiruta, Chandramouli;
Akaishi, Tatsuhiro;
Abe, Kazuho;
Maher, Pamela;
Schubert, David

Publication type:

Article

Fisetin Lowers Methylglyoxal Dependent Protein Glycation and Limits the Complications of Diabetes.

Published in:

PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021226

By:

Maher, Pamela;
Dargusch, Richard;
Ehren, Jennifer L.;
Okada, Shinichi;
Sharma, Kumar;
Schubert, David

Publication type:

Article

Chronic Glutamate Toxicity in Neurodegenerative Diseases--What is the Evidence?

Published in:

Frontiers in Neuroscience, 2015, p. 1, doi. 10.3389/fnins.2015.00469

By:

Lewerenz, Jan;
Maher, Pamela;
Freire, Marco Aurelio M.;
Vickers, James C.

Publication type:

Article

Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain.

Published in:

FASEB Journal, 2017, v. 31, n. 1, p. 5, doi. 10.1096/fj.201601184

By:

Currais, Antonio;
Fischer, Wolfgang;
Maher, Pamela;
Schubert, David

Publication type:

Article

The basic fibroblast growth factor-saporin mitotoxin acts through the basic fibroblast growth factor receptor.

Published in:

Journal of Cellular Physiology, 1991, v. 147, n. 1, p. 17, doi. 10.1002/jcp.1041470104

By:

Lappi, Douglas A.;
Maher, Pamela A.;
Martineau, Darlene;
Baird, Andrew

Publication type:

Article

Comparative study of the tyrosine phosphorylation of proteins in Swiss 3T3 fibroblasts stimulated by a variety of mitogenic agents.

Published in:

Journal of Cellular Physiology, 1988, v. 137, n. 1, p. 146, doi. 10.1002/jcp.1041370118

By:

Pasquale, Elena B.;
Maher, Pamela A.;
Singer, S. J.

Publication type:

Article

Phosphotyrosine-Containing Proteins are Concentrated in Differentiating Cells During Chicken Embryonic Development.

Published in:

Growth Factors, 1993, v. 9, n. 3, p. 243, doi. 10.3109/08977199309010836

By:

Patstone, Gail;
Maher, Pamela A.

Publication type:

Article

The search for anti‐oxytotic/ferroptotic compounds in the plant world.

Published in:

British Journal of Pharmacology, 2021, v. 178, n. 18, p. 3611, doi. 10.1111/bph.15517

By:

Soriano‐Castell, David;
Liang, Zhibin;
Maher, Pamela;
Currais, Antonio

Publication type:

Article

Modulation of 5-Lipoxygenase in Proteotoxicity and Alzheimer's Disease.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 25, p. 10512, doi. 10.1523/JNEUROSCI.5183-12.2013

By:

Valera, Elvira;
Dargusch, Richard;
Maher, Pamela A.;
Schubert, David

Publication type:

Article

Targeting mitochondria for healthy brain aging: a case study of non‐psychoactive cannabinoids to rescue mitochondrial dysfunction in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.062544

By:

Liang, Zhibin;
Maher, Pamela

Publication type:

Article

Transcriptomic signatures of oxytosis/ferroptosis are enriched in Alzheimer's disease.

Published in:

BMC Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12915-025-02235-6

By:

Currais, Antonio;
Sanchez, Kayla;
Soriano-Castell, David;
Dar, Nawab John;
Evensen, K. Garrett;
Soriano, Salvador;
Maher, Pamela

Publication type:

Article

Integrative nuclear FGFR1 signaling (INFS) as a part of a universal feed-forward-and-gate signaling module that controls cell growth and differentiation.

Published in:

Journal of Cellular Biochemistry, 2003, v. 90, n. 4, p. 662, doi. 10.1002/jcb.10606

By:

Michal K. Stachowiak;
Xiaohong Fang;
Jason M. Myers;
Star M. Dunham;
Ronald Berezney;
Pamela A. Maher;
Ewa K. Stachowiak

Publication type:

Article

Fisetin Reduces the Impact of Aging on Behavior and Physiology in the Rapidly Aging SAMP8 Mouse.

Published in:

2018

By:

Currais, Antonio;
Farrokhi, Catherine;
Dargusch, Richard;
Armando, Aaron;
Quehenberger, Oswald;
Schubert, David;
Maher, Pamela

Publication type:

journal article

Methylglyoxal-Induced Protection Response and Toxicity: Role of Glutathione Reductase and Thioredoxin Systems.

Published in:

Neurotoxicity Research, 2017, v. 32, n. 3, p. 340, doi. 10.1007/s12640-017-9738-5

By:

Schmitz, Ariana;
Souza, Luiz;
Santos, Barbara;
Maher, Pamela;
Lopes, Fernanda;
Londero, Giovana;
Klamt, Fabio;
Dafre, Alcir

Publication type:

Article

Characterization of the Neuroprotective Potential of Derivatives of the Iron Chelating Drug Deferiprone.

Published in:

Neurochemical Research, 2015, v. 40, n. 3, p. 609, doi. 10.1007/s11064-014-1508-7

By:

Maher, Pamela;
Kontoghiorghes, George

Publication type:

Article

The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 5, p. 835, doi. 10.1038/jcbfm.2011.189

By:

Gelderblom, Mathias;
Leypoldt, Frank;
Lewerenz, Jan;
Birkenmayer, Gabriel;
Orozco, Denise;
Ludewig, Peter;
Thundyil, John;
Arumugam, Thiruma V;
Gerloff, Christian;
Tolosa, Eva;
Maher, Pamela;
Magnus, Tim

Publication type:

Article

Ligand Dependent and Independent Internalization and Nuclear Translocation of Fibroblast Growth Factor (FGF) Receptor 1.

Published in:

DNA & Cell Biology, 2004, v. 23, n. 9, p. 538, doi. 10.1089/dna.2004.23.538

By:

Reilly, John F.;
Mizukoshi, Eiichi;
Maher, Pamela A.

Publication type:

Article

Regulation of astrocyte GFAP expression by TGF-β1 and FGF-2.

Published in:

Glia (0894-1491), 1998, v. 22, n. 2, p. 202, doi. 10.1002/(SICI)1098-1136(199802)22:2<202::AID-GLIA11>3.0.CO;2-1

By:

Reilly, John F.;
Maher, Pamela A.;
Kumari, Vijaya G.

Publication type:

Article

Editorial: Psychoactive natural products: Potential in the treatment of brain diseases and strategies to improve delivery.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1032496

By:

Cabral, Célia;
Carbone, Claudia;
Maher, Pamela;
Castelo-Branco, Miguel

Publication type:

Article

Phorbol esters inhibit fibroblast growth factor-2-stimulated fibroblast proliferation by a p38 MAP kinase dependent pathway.

Published in:

Oncogene, 2002, v. 21, n. 13, p. 1978, doi. 10.1038/sj.onc.1205268

By:

Maher, Pamela

Publication type:

Article

ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 2, p. 261, doi. 10.1093/hmg/ddq460

By:

Maher, Pamela;
Dargusch, Richard;
Bodai, Laszlo;
Gerard, Paul E.;
Purcell, Judith M.;
Marsh, J. Lawrence

Publication type:

Article

Mechanisms of resistance to oxidative stress in Alzheimer's disease.

Published in:

Biofactors, 1998, v. 8, n. 1/2, p. 45, doi. 10.1002/biof.5520080109

By:

Sagara, Yutaka;
Tan, Shirlee;
Maher, Pamela;
Schubert, David

Publication type:

Article

Fibroblast growth factor receptor signaling affects development and function of dopamine neurons – inhibition results in a schizophrenia-like syndrome in transgenic mice.

Published in:

Journal of Neurochemistry, 2006, v. 97, n. 5, p. 1243, doi. 10.1111/j.1471-4159.2006.03754.x

By:

Klejbor, Ilona;
Myers, Jason M.;
Hausknecht, Kathy;
Corso, Thomas D.;
Gambino, Angelo S.;
Morys, Janusz;
Maher, Pamela A.;
Hard, Robert;
Richards, Jerry;
Stachowiak, Ewa K.;
Stachowiak, Michal K.

Publication type:

Article

Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity.

Published in:

Journal of Neurochemistry, 2005, v. 93, n. 2, p. 493, doi. 10.1111/j.1471-4159.2005.03052.x

By:

Conti, Bruno;
Sugama, Shuei;
Lucero, Jacinta;
Winsky-Sommerer, Raphaelle;
Wirz, Sebastian A.;
Maher, Pamela;
Andrews, Zane;
Barr, Alasdair M.;
Morale, Maria C.;
Paneda, Covadonga;
Pemberton, Janell;
Gaidarova, Svetlana;
Behrens, M. Margarita;
Beal, Flint;
Sanna, Pietro Paolo;
Horvath, Tamas;
Bartfai, Tamas

Publication type:

Article

Induction of PC12 cell differentiation by flavonoids is dependent upon extracellular signal-regulated kinase activation.

Published in:

Journal of Neurochemistry, 2004, v. 90, n. 5, p. 1144, doi. 10.1111/j.1471-4159.2004.02563.x

By:

Sagara, Yutaka;
Vanhnasy, Julie;
Maher, Pamela

Publication type:

Article

Oxidative Stress Induces a Form of Programmed Cell Death with Characteristics of Both Apoptosis and Necrosis in Neuronal Cells.

Published in:

Journal of Neurochemistry, 1998, v. 71, n. 1, p. 95, doi. 10.1046/j.1471-4159.1998.71010095.x

By:

Tan, Shirlee;
Wood, Malcolm;
Maher, Pamela

Publication type:

Article

Schwannoma-Derived Growth Factor Interacts with the Epidermal Growth Factor Receptor.

Published in:

Journal of Neurochemistry, 1995, v. 65, n. 4, p. 1895, doi. 10.1046/j.1471-4159.1995.65041895.x

By:

Maher, Pamela A.;
Schubert, David

Publication type:

Article

CMS121 Partially Attenuates Disease Progression in Mouse Models of Huntington's Disease.

Published in:

Molecular Neurobiology, 2024, v. 61, n. 4, p. 2165, doi. 10.1007/s12035-023-03711-2

By:

Ates, Gamze;
Taguchi, Taketo;
Maher, Pamela

Publication type:

Article

Efficacy of Cannabinoids in a Pre-Clinical Drug-Screening Platform for Alzheimer's Disease.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 11, p. 7719, doi. 10.1007/s12035-019-1637-8

By:

Schubert, David;
Kepchia, Devin;
Liang, Zhibin;
Dargusch, Richard;
Goldberg, Joshua;
Maher, Pamela

Publication type:

Article

Dual activities of 22-24 kda basic fibroblast growth factor: Inhibition of migration and stimulation of proliferation.

Published in:

Journal of Cellular Physiology, 1999, v. 178, n. 2, p. 144, doi. 10.1002/(SICI)1097-4652(199902)178:2<144::AID-JCP3>3.0.CO;2-Z

By:

Piotrowicz, Randolph S.;
Maher, Pamela A.;
Levin, Eugene G.

Publication type:

Article

Identification and characterization of a novel, intracellular isoform of fibroblast growth factor receptor-1 (FGFR-1).

Published in:

Journal of Cellular Physiology, 1996, v. 169, n. 2, p. 380, doi. 10.1002/(SICI)1097-4652(199611)169:2<380::AID-JCP18>3.0.CO;2-D

By:

Maher, Pamela A.

Publication type:

Article

Expression of basic fibroblast growth factor and its receptor in an invasive bladder carcinoma cell line.

Published in:

Journal of Cellular Physiology, 1993, v. 155, n. 2, p. 368, doi. 10.1002/jcp.1041550218

By:

Allen, Lynn E.;
Maher, Pamela A.

Publication type:

Article

Modulation of the epidermal growth factor receptor by basic fibroblast growth factor.

Published in:

Journal of Cellular Physiology, 1993, v. 154, n. 2, p. 350, doi. 10.1002/jcp.1041540219

By:

Maher, Pamela A.

Publication type:

Article

Stimulation of endothelial cell proliferation by vanadate is specific for microvascular endothelial cells.

Published in:

Journal of Cellular Physiology, 1992, v. 151, n. 3, p. 549, doi. 10.1002/jcp.1041510314

By:

Maher, Pamela A.

Publication type:

Article

Practical Implications for Extending Planetarium Instruction Using Motion Sensor Devices and Head-Mounted Displays.

Published in:

Planetarian, 2019, v. 48, n. 4, p. 22

By:

Maher, Pamela A.;
Bailey, Janelle M.;
Schrader, P. G.

Publication type:

Article

How Can Simulations Promote Learning in Science? An Exploratory Study to Examine Two Simulation Tools.

Published in:

Planetarian, 2016, v. 45, n. 1, p. 24

By:

Maher, Pamela A.;
Schrader, P. G.;
Ormord, James;
Kerr, Andrew W.

Publication type:

Article

Delayed treatment with a novel neurotrophic compound reduces behavioral deficits in rabbit ischemic stroke.

Published in:

Journal of Neurochemistry, 2011, v. 116, n. 1, p. 122, doi. 10.1111/j.1471-4159.2010.07090.x

By:

Lapchak, Paul A.;
Schubert, David R.;
Maher, Pamela A.

Publication type:

Article

Lactacidosis modulates glutathione metabolism and oxidative glutamate toxicity.

Published in:

Journal of Neurochemistry, 2010, v. 113, n. 2, p. 502, doi. 10.1111/j.1471-4159.2010.06621.x

By:

Lewerenz, Jan;
Dargusch, Richard;
Maher, Pamela

Publication type:

Article