Works by Mahad, Don

Results: 30

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.

Published in:

Acta Neuropathologica, 2014, v. 128, n. 2, p. 247, doi. 10.1007/s00401-014-1263-5

By:

Schuh, Cornelia;
Wimmer, Isabella;
Hametner, Simon;
Haider, Lukas;
Dam, Anne-Marie;
Liblau, Roland;
Smith, Ken;
Probert, Lesley;
Binder, Christoph;
Bauer, Jan;
Bradl, Monika;
Mahad, Don;
Lassmann, Hans

Publication type:

Article

Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis.

Published in:

Acta Neuropathologica, 2012, v. 124, n. 2, p. 209, doi. 10.1007/s00401-012-1001-9

By:

Campbell, Graham;
Kraytsberg, Yevgenya;
Krishnan, Kim;
Ohno, Nobuhiko;
Ziabreva, Iryna;
Reeve, Amy;
Trapp, Bruce;
Newcombe, Jia;
Reynolds, Richard;
Lassmann, Hans;
Khrapko, Konstantin;
Turnbull, Doug;
Mahad, Don

Publication type:

Article

Temporal lobe cortical pathology and inhibitory GABA interneuron cell loss are associated with seizures in multiple sclerosis.

Published in:

Multiple Sclerosis Journal, 2016, v. 22, n. 1, p. 25, doi. 10.1177/1352458515579445

By:

Nicholas, Richard;
Magliozzi, Roberta;
Campbell, Graham;
Mahad, Don;
Reynolds, Richard

Publication type:

Article

The central role of mitochondria in axonal degeneration in multiple sclerosis.

Published in:

Multiple Sclerosis Journal, 2014, v. 20, n. 14, p. 1806, doi. 10.1177/1352458514544537

By:

Campbell, Graham R;
Worrall, Joseph T;
Mahad, Don J

Publication type:

Article

No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis.

Published in:

Multiple Sclerosis Journal, 2013, v. 19, n. 14, p. 1858, doi. 10.1177/1352458513490547

By:

Campbell, Graham R;
Reeve, Amy K;
Ziabreva, Iryna;
Reynolds, Richard;
Turnbull, Doug M;
Mahad, Don J

Publication type:

Article

The ‘best’ basic science paper on multiple sclerosis in 2012.

Published in:

Multiple Sclerosis Journal, 2013, v. 19, n. 9, p. 1128, doi. 10.1177/1352458513486520

By:

Mahad, Don

Publication type:

Article

Disease-specific molecular events in cortical multiple sclerosis lesions.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 6, p. 1799, doi. 10.1093/brain/awt110

By:

Fischer, Marie Therese;
Wimmer, Isabella;
Höftberger, Romana;
Gerlach, Susanna;
Haider, Lukas;
Zrzavy, Tobias;
Hametner, Simon;
Mahad, Don;
Binder, Christoph J.;
Krumbholz, Markus;
Bauer, Jan;
Bradl, Monika;
Lassmann, Hans

Publication type:

Article

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 3, p. 886, doi. 10.1093/brain/aws012

By:

Fischer, Marie T.;
Sharma, Rakhi;
Lim, Jamie L.;
Haider, Lukas;
Frischer, Josa M.;
Drexhage, Joost;
Mahad, Don;
Bradl, Monika;
van Horssen, Jack;
Lassmann, Hans

Publication type:

Article

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis.

Published in:

Brain: A Journal of Neurology, 2011, v. 134, n. 7, p. 1901, doi. 10.1093/brain/awr110

By:

Zambonin, Jessica L.;
Zhao, Chao;
Ohno, Nobuhiko;
Campbell, Graham R.;
Engeham, Sarah;
Ziabreva, Iryna;
Schwarz, Nadine;
Lee, Sok Ee;
Frischer, Josa M.;
Turnbull, Doug M.;
Trapp, Bruce D.;
Lassmann, Hans;
Franklin, Robin J. M.;
Mahad, Don J.

Publication type:

Article

Mitochondrial changes within axons in multiple sclerosis.

Published in:

2009

By:

Mahad DJ;
Ziabreva I;
Campbell G;
Lax N;
White K;
Hanson PS;
Lassmann H;
Turnbull DM;
Mahad, Don J;
Ziabreva, Iryna;
Campbell, Graham;
Lax, Nichola;
White, Katherine;
Hanson, Peter S;
Lassmann, Hans;
Turnbull, Douglass M

Publication type:

journal article

Mitochondrial changes within axons in multiple sclerosis.

Published in:

Brain: A Journal of Neurology, 2009, v. 132, n. 5, p. 1161, doi. 10.1093/brain/awp046

By:

Mahad, Don J.;
Ziabreva, Iryna;
Campbell, Graham;
Lax, Nichola;
White, Katherine;
Hanson, Peter S.;
Lassmann, Hans;
Turnbull, Douglass M.

Publication type:

Article

Mitochondrial defects in acute multiple sclerosis lesions.

Published in:

Brain: A Journal of Neurology, 2008, v. 131, n. 7, p. 1722, doi. 10.1093/brain/awn105

By:

Don Mahad;
Iryna Ziabreva;
Hans Lassmann;
Douglas Turnbull

Publication type:

Article

Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis.

Published in:

2006

By:

Mahad D;
Callahan MK;
Williams KA;
Ubogu EE;
Kivisäkk P;
Tucky B;
Kidd G;
Kingsbury GA;
Chang A;
Fox RJ;
Mack M;
Sniderman MB;
Ravid R;
Staugaitis SM;
Stins MF;
Ransohoff RM;
Mahad, Don;
Callahan, Melissa K;
Williams, Katherine A;
Ubogu, Eroboghene E

Publication type:

journal article

Modulating CCR2 and CCL2 at the bloodbrain barrier: relevance for multiple sclerosis pathogenesis.

Published in:

Brain: A Journal of Neurology, 2006, v. 129, n. 1, p. 212, doi. 10.1093/brain/awh655

By:

Don Mahad;
Melissa K. Callahan

Publication type:

Article

Chemokines and chemokine receptors in inflammatory demyelinating neuropathies: a central role for IP‐10.

Published in:

Brain: A Journal of Neurology, 2002, v. 125, n. 4, p. 823, doi. 10.1093/brain/awf070

By:

Kieseier, Bernd C.;
Tani, Marie;
Mahad, Don;
Oka, Nobuyuki;
Ho, Tony;
Woodroofe, Nicola;
Griffin, John W.;
Toyka, Klaus V.;
Ransohoff, Richard M.;
Hartung, Hans‐Peter

Publication type:

Article

Neurofascin 140 Is an Embryonic Neuronal Neurofascin Isoform That Promotes the Assembly of the Node of Ranvier.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 5, p. 2246, doi. 10.1523/JNEUROSCI.3552-14.2015

By:

Ao Zhang;
Desmazieres, Anne;
Zonta, Barbara;
Melrose, Shona;
Campbell, Graham;
Mahad, Don;
Qiushi Li;
Sherman, Diane L.;
Reynolds, Richard;
Brophy, Peter J.

Publication type:

Article

Mitochondria as Crucial Players in Demyelinated Axons: Lessons from Neuropathology and Experimental Demyelination.

Published in:

Autoimmune Diseases (2090-0422), 2011, p. 1, doi. 10.4061/2011/262847

By:

Campbell, Graham R.;
Mahad, Don J.

Publication type:

Article

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis.

Published in:

Annals of Neurology, 2011, v. 69, n. 3, p. 481, doi. 10.1002/ana.22109

By:

Campbell, Graham R.;
Ziabreva, Iryna;
Reeve, Amy K.;
Krishnan, Kim J.;
Reynolds, Richard;
Howell, Owen;
Lassmann, Hans;
Turnbull, Doug M.;
Mahad, Don J.

Publication type:

Article

Expression of CCR7 in multiple sclerosis: Implications for CNS immunity.

Published in:

Annals of Neurology, 2004, v. 55, n. 5, p. 627

By:

Pia Kivisäkk;
Don J. Mahad;
Melissa K. Callahan;
Keith Sikora;
Corinna Trebst;
Barbara Tucky;
Jerome Wujek;
Rivka Ravid;
Susan M. Staugaitis;
Hans Lassmann;
Richard M. Ransohoff

Publication type:

Article

A Targeted Mutation Disrupting Mitochondrial Complex IV Function in Primary Afferent Neurons Leads to Pain Hypersensitivity Through P2Y<sub>1</sub> Receptor Activation.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 8, p. 5917, doi. 10.1007/s12035-018-1455-4

By:

Mitchell, Rory;
Campbell, Graham;
Mikolajczak, Marta;
McGill, Katie;
Mahad, Don;
Fleetwood-Walker, Sue M.

Publication type:

Article

Mitochondrial dysfunction and axon degeneration in progressive multiple sclerosis.

Published in:

FEBS Letters, 2018, v. 592, n. 7, p. 1113, doi. 10.1002/1873-3468.13013

By:

Campbell, Graham;
Mahad, Don J.

Publication type:

Article

Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short-term facilitation at mossy fibre to CA3 pyramidal cell synapses.

Published in:

Journal of Physiology, 2017, v. 595, n. 6, p. 2147, doi. 10.1113/JP273581

By:

Booker, Sam A.;
Campbell, Graham R.;
Mysiak, Karolina S.;
Brophy, Peter J.;
Kind, Peter C.;
Mahad, Don J.;
Wyllie, David J. A.

Publication type:

Article

Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes.

Published in:

Glia (0894-1491), 2010, v. 58, n. 15, p. 1827, doi. 10.1002/glia.21052

By:

Ziabreva, Iryna;
Campbell, Graham;
Rist, Julia;
Zambonin, Jessica;
Rorbach, Joanna;
Wydro, Mateusz M.;
Lassmann, Hans;
Franklin, Robin J. M.;
Mahad, Don

Publication type:

Article

Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.

Published in:

Acta Neuropathologica, 2021, v. 141, n. 2, p. 257, doi. 10.1007/s00401-020-02252-5

By:

Mehta, Arpan R.;
Gregory, Jenna M.;
Dando, Owen;
Carter, Roderick N.;
Burr, Karen;
Nanda, Jyoti;
Story, David;
McDade, Karina;
Smith, Colin;
Morton, Nicholas M.;
Mahad, Don J.;
Hardingham, Giles E.;
Chandran, Siddharthan;
Selvaraj, Bhuvaneish T.

Publication type:

Article

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.

Published in:

2017

By:

Syed, Yasir;
Zhao, Chao;
Mahad, Don;
Möbius, Wiebke;
Altmann, Friedrich;
Foss, Franziska;
González, G.;
Sentürk, Aycan;
Acker-Palmer, Amparo;
Lubec, Gert;
Lilley, Kathryn;
Franklin, Robin;
Nave, Klaus-A.;
Kotter, Mark

Publication type:

Erratum

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.

Published in:

2016

By:

Syed, Yasir;
Zhao, Chao;
Mahad, Don;
Möbius, Wiebke;
Altmann, Friedrich;
Foss, Franziska;
González, G.;
Sentürk, Aycan;
Acker-Palmer, Amparo;
Lubec, Gert;
Lilley, Kathryn;
Franklin, Robin;
Nave, Klaus-A.;
Kotter, Mark

Publication type:

Erratum

Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.

Published in:

Acta Neuropathologica, 2016, v. 131, n. 2, p. 281, doi. 10.1007/s00401-015-1521-1

By:

Syed, Yasir;
Zhao, Chao;
Mahad, Don;
Möbius, Wiebke;
Altmann, Friedrich;
Foss, Franziska;
Sentürk, Aycan;
Acker-Palmer, Amparo;
Lubec, Gert;
Lilley, Kathryn;
Franklin, Robin;
Nave, Klaus-A.;
Kotter, Mark

Publication type:

Article

Mitochondrial fission augments capsaicin-induced axonal degeneration.

Published in:

Acta Neuropathologica, 2015, v. 129, n. 1, p. 81, doi. 10.1007/s00401-014-1354-3

By:

Chiang, Hao;
Ohno, Nobuhiko;
Hsieh, Yu-Lin;
Mahad, Don;
Kikuchi, Shin;
Hsieh, Sung-Tsang;
Komuro, Hitoshi;
Trapp, Bruce

Publication type:

Article

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity.

Published in:

Nature, 2012, v. 485, n. 7399, p. 517, doi. 10.1038/nature11007

By:

Fünfschilling, Ursula;
Supplie, Lotti M.;
Mahad, Don;
Boretius, Susann;
Saab, Aiman S.;
Edgar, Julia;
Brinkmann, Bastian G.;
Kassmann, Celia M.;
Tzvetanova, Iva D.;
Möbius, Wiebke;
Diaz, Francisca;
Meijer, Dies;
Suter, Ueli;
Hamprecht, Bernd;
Sereda, Michael W.;
Moraes, Carlos T.;
Frahm, Jens;
Goebbels, Sandra;
Nave, Klaus-Armin

Publication type:

Article

Myelination and Axonal Electrical Activity Modulate the Distribution and Motility of Mitochondria at CNS Nodes of Ranvier.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 20, p. 7249, doi. 10.1523/JNEUROSCI.0095-11.2011

By:

Ohno, Nobuhiko;
Kidd, Grahame J.;
Mahad, Don;
Kiryu-Seo, Sumiko;
Avishai, Amir;
Komuro, Hitoshi;
Trapp, Bruce D.

Publication type:

Article