Works by Magin, Thomas M.

Results: 47

MEK inhibitor cobimetinib rescues a dRaf mutant lethal phenotype in Drosophila melanogaster.

Published in:

Experimental Dermatology, 2019, v. 28, n. 9, p. 1079, doi. 10.1111/exd.14010

By:

Pfeifle, Isabelle;
Bohnekamp, Jens;
Volkhardt, Anna;
Kirsten, Holger;
Rohwedder, Astrid;
Thum, Andreas;
Magin, Thomas M.;
Kunz, Manfred

Publication type:

Article

Orf virus infection of human keratinocytes and dermal fibroblasts: Limited virus detection and interference with intercellular adhesion molecule‐1 up‐regulation.

Published in:

Experimental Dermatology, 2019, v. 28, n. 2, p. 142, doi. 10.1111/exd.13861

By:

Schneider, Laura E.;
Protschka, Martina;
Müller, Uwe;
Muhsen, Mahmod;
Büttner, Mathias;
Alber, Gottfried;
Siegemund, Sabine;
Magin, Thomas M.;
Anderegg, Ulf;
Saalbach, Anja

Publication type:

Article

Involvement of the ubiquitin-proteasome system in the stabilization of cell-cell contacts in human keratinocytes.

Published in:

Experimental Dermatology, 2012, v. 21, n. 10, p. 791, doi. 10.1111/j.1600-0625.2012.01564.x

By:

Löffek, Stefanie;
Bruckner-Tuderman, Leena;
Magin, Thomas M.

Publication type:

Article

Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00528

By:

Vielmuth, Franziska;
Walter, Elias;
Fuchs, Michael;
Radeva, Mariya Y.;
Buechau, Fanny;
Magin, Thomas M.;
Spindler, Volker;
Waschke, Jens

Publication type:

Article

Keratin function and regulation in tissue homeostasis and pathogenesis.

Published in:

Biomolecular Concepts, 2012, v. 3, n. 2, p. 161, doi. 10.1515/bmc.2011.060

By:

Roth, Wera;
Hatzfeld, Mechthild;
Friedrich, Maik;
Thiering, Sören;
Magin, Thomas M.

Publication type:

Article

Structural heterogeneity of cellular K5/ K14 filaments as revealed by cryoelectron microscopy.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.70307

By:

Weber, Miriam S.;
Eibauer, Matthias;
Sivagurunathan, Suganya;
Magin, Thomas M.;
Goldman, Robert D.;
Medalia, Ohad

Publication type:

Article

Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo.

Published in:

EMBO Journal, 2022, v. 41, n. 7, p. 1, doi. 10.15252/embj.2021108747

By:

Nahaboo, Wallis;
Eski, Sema Elif;
Despin‐Guitard, Evangéline;
Vermeersch, Marjorie;
Versaevel, Marie;
Saykali, Bechara;
Monteyne, Daniel;
Gabriele, Sylvain;
Magin, Thomas M;
Schwarz, Nicole;
Leube, Rudolf E;
Zwijsen, An;
Perez‐Morga, David;
Singh, Sumeet Pal;
Migeotte, Isabelle

Publication type:

Article

Cx31 and Cx43 double-deficient mice reveal independent functions in murine placental and skin development.

Published in:

Developmental Dynamics, 2005, v. 233, n. 3, p. 853

By:

Mark Kibschull;
Thomas M. Magin;
Otto Traub;
Elke Winterhager

Publication type:

Article

Animal models of human skin disease.

Published in:

2004

By:

Magin, Thomas M.

Publication type:

Other

A keaper and a striker maintain epidermal homeostasis.

Published in:

Nature Genetics, 2003, v. 35, n. 3, p. 202, doi. 10.1038/ng1103-202

By:

Magin, Thomas M.

Publication type:

Article

Dissection of keratin network formation, turnover and reorganization in living murine embryos.

Published in:

Scientific Reports, 2015, p. 9007, doi. 10.1038/srep09007

By:

Schwarz, Nicole;
Windoffer, Reinhard;
Magin, Thomas M.;
Leube, Rudolf E.

Publication type:

Article

Mitogen‐activated protein kinase pathway inhibitors rescue lethal phenotypes in a BRAF gain‐of‐function Drosophila melanogaster model.

Published in:

2018

By:

Volkhardt, Anna;
Bohnekamp, Jens;
Pfeifle, Isabelle;
Engel, Christoph;
Magin, Thomas M.;
Kunz, Manfred

Publication type:

Letter to the Editor

Genomewide RNAi screen identifies protein kinase Cβ and new members of mitogen-activated protein kinase pathway as regulators of melanoma cell growth and metastasis.

Published in:

Pigment Cell & Melanoma Research, 2014, v. 27, n. 3, p. 418, doi. 10.1111/pcmr.12216

By:

Schönherr, Madeleine;
Bhattacharya, Animesh;
Kottek, Tina;
Szymczak, Silke;
Köberle, Margarethe;
Wickenhauser, Claudia;
Siebolts, Udo;
Saalbach, Anja;
Koczan, Dirk;
Magin, Thomas M.;
Simon, Jan C.;
Kunz, Manfred

Publication type:

Article

Orf virus (ORFV) infection in a three-dimensional human skin model: Characteristic cellular alterations and interference with keratinocyte differentiation.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0210504

By:

Muhsen, Mahmod;
Protschka, Martina;
Schneider, Laura E.;
Müller, Uwe;
Köhler, Gabriele;
Magin, Thomas M.;
Büttner, Mathias;
Alber, Gottfried;
Siegemund, Sabine

Publication type:

Article

The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.

Published in:

Human Mutation, 2010, v. 31, n. 4, p. 466, doi. 10.1002/humu.21222

By:

Löffek, Stefanie;
Wöll, Stefan;
Höhfeld, Jörg;
Leube, Rudolf E.;
Has, Cristina;
Bruckner-Tuderman, Leena;
Magin, Thomas M.

Publication type:

Article

Cytokines as genetic modifiers in K5<sup>-/-</sup> mice and in human epidermolysis bullosa simplex.

Published in:

Human Mutation, 2009, v. 30, n. 5, p. 832, doi. 10.1002/humu.20981

By:

Roth, Wera;
Reuter, Ursula;
Wohlenberg, Claudia;
Bruckner-Tuderman, Leena;
Magin, Thomas M.

Publication type:

Article

Denaturing temperature selection may underestimate keratin mutation detection by DHPLC.

Published in:

Human Mutation, 2006, v. 27, n. 5, p. 444, doi. 10.1002/humu.20311

By:

Strnad, Pavel;
Lienau, Tim Christian;
Tao, Guo-Zhong;
Ku, Nam-On;
Magin, Thomas M.;
Omary, M. Bishr

Publication type:

Article

Bidirectional regulation of desmosome hyperadhesion by keratin isotypes and desmosomal components.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 5, p. 1, doi. 10.1007/s00018-022-04244-y

By:

Büchau, Fanny;
Vielmuth, Franziska;
Waschke, Jens;
Magin, Thomas M.

Publication type:

Article

An intact keratin network is crucial for mechanical integrity and barrier function in keratinocyte cell sheets.

Published in:

Cellular & Molecular Life Sciences, 2020, v. 77, n. 21, p. 4397, doi. 10.1007/s00018-019-03424-7

By:

Karsch, Susanne;
Büchau, Fanny;
Magin, Thomas M.;
Janshoff, Andreas

Publication type:

Article

Plectin in the human central nervous system: predominant expression at pia/glia and endothelia/glia interfaces.

Published in:

Acta Neuropathologica, 1998, v. 96, n. 3, p. 215, doi. 10.1007/s004010050885

By:

Lie, A. A.;
Schröder, R.;
Blümcke, Ingmar;
Magin, Thomas M.;
Wiestler, Otmar D.;
Elger, Christian E.

Publication type:

Article

Keratins control intercellular adhesion involving PKC-α-mediated desmoplakin phosphorylation.

Published in:

Journal of Cell Biology, 2013, v. 201, n. 5, p. 681, doi. 10.1083/jcb.201208162

By:

Kröger, Cornelia;
Loschke, Fanny;
Schwarz, Nicole;
Windoffer, Reinhard;
Leube, Rudolf E.;
Magin, Thomas M.

Publication type:

Article

Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithelia.

Published in:

Journal of Cell Biology, 2011, v. 194, n. 5, p. 669, doi. 10.1083/jcb.201008095

By:

Windoffer, Reinhard;
Beil, Michael;
Magin, Thomas M.;
Leube, Rudolf E.

Publication type:

Article

Keratins regulate protein biosynthesis through localization of GLUT1 and-3 upstream of AMP kinase and Raptor.

Published in:

Journal of Cell Biology, 2009, v. 187, n. 2, p. 175, doi. 10.1083/jcb.200906094

By:

Vijayaraj, Preethi;
Kröger, Cornelia;
Reuter, Ursula;
Windoffer, Reinhard;
Leube, Rudolf E.;
Magin, Thomas M.

Publication type:

Article

New consensus nomenclature for mammalian keratins.

Published in:

Journal of Cell Biology, 2006, v. 174, n. 2, p. 169, doi. 10.1083/jcb.200603161

By:

Schweizer, Jürgen;
Rogers, Michael A.;
Langbein, Lutz;
Bowden, Paul E.;
Coulombe, Pierre A.;
Lane, E. Birgitte;
Magin, Thomas M.;
Maltais, Lois;
Omary, M. Bishr;
Parry, David A. D.;
Wright, Mathew W.

Publication type:

Article

Immunofluorescence analysis of sensory nerve endings in the interosseous membrane of the forearm.

Published in:

Journal of Anatomy, 2020, v. 236, n. 5, p. 906, doi. 10.1111/joa.13138

By:

Rein, Susanne;
Esplugas, Mireia;
Garcia‐Elias, Marc;
Magin, Thomas M.;
Randau, Thomas M.;
Siemers, Frank;
Philipps, Hubertus M.

Publication type:

Article

Loss of Keratin 10 Leads to Mitogen-activated Protein Kinase (MAPK) Activation, Increased Keratinocyte Turnover, and Decreased Tumor Formation in Mice.

Published in:

Journal of Investigative Dermatology, 2004, v. 123, n. 5, p. 973, doi. 10.1111/j.0022-202X.2004.23426.x

By:

Reichelt, Julia;
Furstenberger, Gerhard;
Magin, Thomas M.

Publication type:

Article

Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles.

Published in:

Journal of Investigative Dermatology, 2002, v. 119, n. 1, p. 32, doi. 10.1046/j.1523-1747.2002.01806.x

By:

Porter, Rebecca M.;
Jahoda, Colin A. B.;
Lunny, Declan P.;
Henderson, Gayle;
Ross, Jane;
Irwin McLean, W. H.;
Whittock, Neil V.;
Wilson, Neil J.;
Reichelt, Julia;
Magin, Thomas M.;
Lane, E. Birgitte

Publication type:

Article

Skin-Specific Expression of ank-3<sub>93</sub>, a Novel Ankyrin-3 Splice Variant.

Published in:

Journal of Investigative Dermatology, 2001, v. 116, n. 2, p. 216, doi. 10.1046/j.1523-1747.2001.01210.x

By:

Peters, Bettina;
Kaiser, Hans Wilhelm;
Magin, Thomas M.

Publication type:

Article

The Relationship Between Hyperproliferation and Epidermal Thickening in a Mouse Model for BCIE.

Published in:

Journal of Investigative Dermatology, 1998, v. 110, n. 6, p. 951, doi. 10.1046/j.1523-1747.1998.00218.x

By:

Porter, Rebecca M.;
Reichelt, Julia;
Lunny, Declan P.;
Magin, Thomas M.;
Lane, E. Birgitte

Publication type:

Article

Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality.

Published in:

EMBO Journal, 2000, v. 19, n. 19, p. 5060, doi. 10.1093/emboj/19.19.5060

By:

Hesse, Michael;
Franz, Thomas;
Tamai, Yoshitaka;
Taketo, Makoto M.;
Magin, Thomas M.

Publication type:

Article

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

Published in:

Journal of Cell Biology, 2015, v. 211, n. 5, p. 1057, doi. 10.1083/jcb.201404147

By:

Kumar, Vinod;
Bouameur, Jamal-Eddine;
Bär, Janina;
Rice, Robert H.;
Hue-Tran Hornig-Do;
Roop, Dennis R.;
Schwarz, Nicole;
Brodesser, Susanne;
Thiering, Sören;
Leube, Rudolf E.;
Wiesner, Rudolf J.;
Brazel, Christina B.;
Heller, Sandra;
Binder, Hans;
Loffler-Wirth, Henry;
Seibel, Peter;
Magin, Thomas M.

Publication type:

Article

Mouse Keratinocytes Without Keratin Intermediate Filaments Demonstrate Substrate Stiffness Dependent Behaviors.

Published in:

Cellular & Molecular Bioengineering, 2018, v. 11, n. 3, p. 163, doi. 10.1007/s12195-018-0526-y

By:

Zarkoob, Hoda;
Chinnathambi, Sathivel;
Halberg, Spencer A.;
Selby, John C.;
Magin, Thomas M.;
Sander, E. A.

Publication type:

Article

Biomolecule Function: No Reliable Prediction from Cell Culture.

Published in:

Traffic, 2000, v. 1, n. 10, p. 803, doi. 10.1034/j.1600-0854.2000.011007.x

By:

Kolter, Thomas;
Magin, Thomas M.;
Sandhoff, Konrad

Publication type:

Article

Dominant cataract formation in association with a vimentin assembly disrupting mutation.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 6, p. 1052, doi. 10.1093/hmg/ddn440

By:

Müller, Martin;
Bhattacharya, Shomi S.;
Moore, Tony;
Prescott, Quincy;
Wedig, Tatjana;
Herrmann, Harald;
Magin, Thomas M.

Publication type:

Article

Loss of the Keratin Cytoskeleton Is Not Sufficient to Induce Epithelial Mesenchymal Transition in a Novel KRAS Driven Sporadic Lung Cancer Mouse Model.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057996

By:

König, Katharina;
Meder, Lydia;
Kröger, Cornelia;
Diehl, Linda;
Florin, Alexandra;
Rommerscheidt-Fuss, Ursula;
Kahl, Philip;
Wardelmann, Eva;
Magin, Thomas M.;
Buettner, Reinhard;
Heukamp, Lukas C.

Publication type:

Article

Novel origin of lamin-derived cytoplasmic intermediate filaments in tardigrades.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.11117

By:

Hering, Lars;
Bouameur, Jamal-Eddine;
Reichelt, Julian;
Magin, Thomas M.;
Mayer, Georg

Publication type:

Article

Correction: Winkler et al. The Adhesion G-Protein-Coupled Receptor GPR115/ ADGRF4 Regulates Epidermal Differentiation and Associates with Cytoskeletal KRT1. Cells 2022, 11 , 3151.

Published in:

2023

By:

Winkler, Romy;
Quaas, Marianne;
Glasmacher, Stefan;
Wolfrum, Uwe;
Thalheim, Torsten;
Galle, Jörg;
Krohn, Knut;
Magin, Thomas M.;
Aust, Gabriela

Publication type:

Correction Notice

The Adhesion G-Protein-Coupled Receptor GPR115/ ADGRF4 Regulates Epidermal Differentiation and Associates with Cytoskeletal KRT1.

Published in:

Cells (2073-4409), 2022, v. 11, n. 19, p. 3151, doi. 10.3390/cells11193151

By:

Winkler, Romy;
Quaas, Marianne;
Glasmacher, Stefan;
Wolfrum, Uwe;
Thalheim, Torsten;
Galle, Jörg;
Krohn, Knut;
Magin, Thomas M.;
Aust, Gabriela

Publication type:

Article

Distinct Impact of Two Keratin Mutations Causing Epidermolysis Bullosa Simplex on Keratinocyte Adhesion and Stiffness.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 10, p. 2437, doi. 10.1038/jid.2015.184

By:

Homberg, Melanie;
Ramms, Lena;
Schwarz, Nicole;
Dreissen, Georg;
Leube, Rudolf E;
Merkel, Rudolf;
Hoffmann, Bernd;
Magin, Thomas M

Publication type:

Article

A Drosophila Model of Epidermolysis Bullosa Simplex.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 8, p. 2031, doi. 10.1038/jid.2015.129

By:

Bohnekamp, Jens;
Cryderman, Diane E;
Paululat, Achim;
Baccam, Gabriel C;
Wallrath, Lori L;
Magin, Thomas M

Publication type:

Article

Keratins Stabilize Hemidesmosomes through Regulation of β4-Integrin Turnover.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 6, p. 1609, doi. 10.1038/jid.2015.46

By:

Seltmann, Kristin;
Cheng, Fang;
Wiche, Gerhard;
Eriksson, John E;
Magin, Thomas M

Publication type:

Article

Skin Fragility and Impaired Desmosomal Adhesion in Mice Lacking All Keratins.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 4, p. 1012, doi. 10.1038/jid.2013.416

By:

Bär, Janina;
Kumar, Vinod;
Roth, Wera;
Schwarz, Nicole;
Richter, Miriam;
Leube, Rudolf E;
Magin, Thomas M

Publication type:

Article

Keratins Mediate Localization of Hemidesmosomes and Repress Cell Motility.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 1, p. 181, doi. 10.1038/jid.2012.256

By:

Seltmann, Kristin;
Roth, Wera;
Kröger, Cornelia;
Loschke, Fanny;
Lederer, Marcell;
Hüttelmaier, Stefan;
Magin, Thomas M

Publication type:

Article

Targeting the Palm: A Leap Forward Toward Treatment of Keratin Disorders.

Published in:

Journal of Investigative Dermatology, 2012, v. 132, n. 6, p. 1541, doi. 10.1038/jid.2012.99

By:

Roth, Wera;
Hatzfeld, Mechthild;
Magin, Thomas M.

Publication type:

Article

Induction of Inflammatory Cytokines by a Keratin Mutation and their Repression by a Small Molecule in a Mouse Model for EBS.

Published in:

Journal of Investigative Dermatology, 2007, v. 127, n. 12, p. 2781, doi. 10.1038/sj.jid.5700918

By:

Hong Lu;
Jian Chen;
Planko, Laura;
Zigrino, Paola;
Klein-Hitpass, Ludger;
Magin, Thomas M.

Publication type:

Article

Mechanisms of Fibroblast Cell Therapy for Dystrophic Epidermolysis Bullosa: High Stability of Collagen VII Favors Long-term Skin Integrity.

Published in:

Molecular Therapy, 2009, v. 17, n. 9, p. 1605, doi. 10.1038/mt.2009.144

By:

Kern, Johannes S.;
Loeckermann, Stefan;
Fritsch, Anja;
Hausser, Ingrid;
Roth, Wera;
Magin, Thomas M.;
Mack, Claudia;
Müller, Marcel L.;
Paul, Oliver;
Ruther, Patrick;
Bruckner-Tuderman, Leena

Publication type:

Article

Insulin receptor plays a central role in skin carcinogenesis by regulating cytoskeleton assembly.

Published in:

FASEB Journal, 2019, v. 33, n. 2, p. 2241, doi. 10.1096/fj.201800847R

By:

Weingarten, Galina;
Yaakov, Aya Ben;
Dror, Erez;
Russ, Jenny;
Magin, Thomas M.;
Kahn, C. Ronald;
Wertheimer, Efrat

Publication type:

Article