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GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
- Published in:
- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01654-0
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- Publication type:
- Article
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
- Published in:
- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01654-0
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- Publication type:
- Article
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
- Published in:
- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01654-0
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- Publication type:
- Article
Promising Perspectives of the Antiproliferative GPER Inverse Agonist ERα17p in Breast Cancer.
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- Cells (2073-4409), 2023, v. 12, n. 4, p. 653, doi. 10.3390/cells12040653
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- Publication type:
- Article
Role of the G Protein-Coupled Receptors in Cancer and Stromal Cells: From Functions to Novel Therapeutic Perspectives.
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- Cells (2073-4409), 2023, v. 12, n. 4, p. 626, doi. 10.3390/cells12040626
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- Publication type:
- Article
The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells.
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- Cells (2073-4409), 2022, v. 11, n. 15, p. 2402, doi. 10.3390/cells11152402
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- Publication type:
- Article
Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells.
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- Cells (2073-4409), 2021, v. 10, n. 11, p. 3145, doi. 10.3390/cells10113145
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- Publication type:
- Article
Role of Gonadotropin-Releasing Hormone (GnRH) in Ovarian Cancer.
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- Cells (2073-4409), 2021, v. 10, n. 2, p. 437, doi. 10.3390/cells10020437
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- Publication type:
- Article
Correction: Rigiracciolo, D.C., et al., IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells. Cells 2020, 9, 1010.
- Published in:
- 2020
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- Publication type:
- Correction Notice
IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 4, p. 1010, doi. 10.3390/cells9041010
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- Publication type:
- Article
The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis.
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- Cells (2073-4409), 2020, v. 9, n. 3, p. 622, doi. 10.3390/cells9030622
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- Publication type:
- Article
Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology.
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- Cells (2073-4409), 2020, v. 9, n. 2, p. 447, doi. 10.3390/cells9020447
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- Publication type:
- Article
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells.
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- Cells (2073-4409), 2019, v. 8, n. 6, p. 590, doi. 10.3390/cells8060590
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- Publication type:
- Article
GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression.
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- Cells (2073-4409), 2019, v. 8, n. 3, p. 223, doi. 10.3390/cells8030223
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- Publication type:
- Article
miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs).
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- Cells (2073-4409), 2018, v. 7, n. 11, p. 203, doi. 10.3390/cells7110203
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- Publication type:
- Article
Commentary: harnessing the first peptidic modulator of the estrogen receptor GPER.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1413058
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- Publication type:
- Article
Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation.
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- Oncogene, 2002, v. 21, n. 42, p. 6434, doi. 10.1038/sj.onc.1205822
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- Publication type:
- Article
Pharmacotherapeutic Targeting of G Protein-Coupled Receptors in Oncology: Examples of Approved Therapies and Emerging Concepts.
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- Drugs, 2017, v. 77, n. 9, p. 951, doi. 10.1007/s40265-017-0738-9
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- Publication type:
- Article
miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0767-6
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- Publication type:
- Article
Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.
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- Molecular Nutrition & Food Research, 2010, v. 54, n. 6, p. 833, doi. 10.1002/mnfr.200900111
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- Publication type:
- Article
Structure-activity relationships of resveratrol and derivatives in breast cancer cells.
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- Molecular Nutrition & Food Research, 2009, v. 53, n. 7, p. 845, doi. 10.1002/mnfr.200800331
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- Publication type:
- Article
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 435, doi. 10.3390/ijms25010435
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- Publication type:
- Article
G-Protein-Coupled Estrogen Receptor Expression in Rat Uterine Artery Is Increased by Pregnancy and Induces Dilation in a Ca 2+ and ERK1/2 Dependent Manner.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 5996, doi. 10.3390/ijms23115996
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- Publication type:
- Article
S100A4 Is Involved in Stimulatory Effects Elicited by the FGF2/FGFR1 Signaling Pathway in Triple-Negative Breast Cancer (TNBC) Cells.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4720, doi. 10.3390/ijms22094720
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- Publication type:
- Article
Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7797, doi. 10.3390/ijms21207797
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- Publication type:
- Article
GPCR Modulation in Breast Cancer.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3840, doi. 10.3390/ijms19123840
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- Publication type:
- Article
Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMT.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 7, p. 2011, doi. 10.3390/ijms19072011
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- Article
G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 12, p. 2713, doi. 10.3390/ijms18122713
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- Publication type:
- Article
Fibronectin and type IV collagen activate ERaAF-1 by c-Src pathway: effect on breast cancer cell motility.
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- Oncogene, 2004, v. 23, n. 55, p. 8920, doi. 10.1038/sj.onc.1208098
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- Publication type:
- Article
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC).
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- Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02396-0
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- Publication type:
- Article
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC).
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- Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02396-0
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- Publication type:
- Article
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells.
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- Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05269-6
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- Publication type:
- Article
Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth.
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- Breast Cancer Research & Treatment, 2014, v. 146, n. 2, p. 273, doi. 10.1007/s10549-014-3017-4
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- Article
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts.
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- Clinical & Translational Medicine, 2021, v. 11, n. 11, p. 1, doi. 10.1002/ctm2.516
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- Article
Notch1 Mediates Preconditioning Protection Induced by GPER in Normotensive and Hypertensive Female Rat Hearts.
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- Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00521
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- Article
Differential expression of estrogen receptors (ERα/ERβ) in testis of mature and immature pigs.
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- Anatomical Record: Advances in Integrative Anatomy & Evolutionary Biology, 2004, v. 281A, n. 2, p. 1234, doi. 10.1002/ar.a.20131
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- Article
GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment.
- Published in:
- 2017
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- Publication type:
- journal article
The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs).
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2020, v. 39, n. 1, p. 1, doi. 10.1186/s13046-020-01667-y
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- Publication type:
- Article
Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells.
- Published in:
- Molecular Nutrition & Food Research, 2014, v. 58, n. 3, p. 478, doi. 10.1002/mnfr.201300323
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- Publication type:
- Article
GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts.
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- Molecular Carcinogenesis, 2017, v. 56, n. 2, p. 580, doi. 10.1002/mc.22518
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- Publication type:
- Article
GPER Mediates Cardiotropic Effects in Spontaneously Hypertensive Rat Hearts.
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- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0069322
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- Publication type:
- Article
The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes.
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- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016631
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- Publication type:
- Article
GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response.
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- Scientific Reports, 2016, p. 24354, doi. 10.1038/srep24354
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- Publication type:
- Article
DDR1 Affects Metabolic Reprogramming in Breast Cancer Cells by Cross-Talking to the Insulin/IGF System.
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- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 926, doi. 10.3390/biom11070926
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- Publication type:
- Article
Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF.
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- EMBO Journal, 2009, v. 28, n. 5, p. 523, doi. 10.1038/emboj.2008.304
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- Publication type:
- Article
Interleukin (IL)-11 Is Involved in the Functional Liaison between Breast Tumor Cells and the Surrounding Stroma †.
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- Biology & Life Sciences Forum, 2023, v. 21, n. 1, p. 23, doi. 10.3390/blsf2023021023
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- Publication type:
- Article
Mechanistic Insights on the Anticancer Effects of Metformin in Primary Breast Cancer Cells †.
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- Biology & Life Sciences Forum, 2023, v. 21, n. 1, p. 18, doi. 10.3390/blsf2023021018
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- Publication type:
- Article
Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells—identification of a novel androgen response element.
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- Nucleic Acids Research, 2010, v. 38, n. 16, p. 5351, doi. 10.1093/nar/gkq278
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- Publication type:
- Article
Novel aspects concerning the functional cross-talk between the insulin/IGF-I system and estrogen signaling in cancer cells.
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- Frontiers in Endocrinology, 2015, v. 6, p. 1, doi. 10.3389/fendo.2015.00030
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- Article
GPER function in breast cancer: an overview.
- Published in:
- Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00066
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- Publication type:
- Article