Works matching AU Mager, Donald E.

Results: 71

Population Pharmacokinetics of Tacrolimus in Transplant Recipients: What Did We Learn About Sources of Interindividual Variabilities?

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 3, p. 309, doi. 10.1002/jcph.1325

By:

Campagne, Olivia;
Mager, Donald E.;
Tornatore, Kathleen M.

Publication type:

Article

Population Pharmacokinetics and Pharmacodynamics of Carfilzomib in Combination with Rituximab, Ifosfamide, Carboplatin, and Etoposide in Adult Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma.

Published in:

Targeted Oncology, 2023, v. 18, n. 5, p. 685, doi. 10.1007/s11523-023-00992-4

By:

Lin, Lan-Hsi;
Ghasemi, Mohammad;
Burke, Sarah M.;
Mavis, Cory K.;
Nichols, Jenna R.;
Torka, Pallawi;
Mager, Donald E.;
Hernandez-Ilizaliturri, Francisco J.;
Goey, Andrew K. L.

Publication type:

Article

Enantioselective pharmacokinetics of ( R)- and ( S)-ketamine after a 5-day infusion in patients with complex regional pain syndrome.

Published in:

Chirality, 2011, v. 23, n. 2, p. 138, doi. 10.1002/chir.20890

By:

Goldberg, Michael E.;
Torjman, Marc C.;
Schwartzman, Robert J.;
Mager, Donald E.;
Wainer, Irving W.

Publication type:

Article

Quantitative systems pharmacology modeling of tumor heterogeneity in response to BH3‐mimetics using virtual tumors calibrated with cell viability assays.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 7, p. 1252, doi. 10.1002/psp4.13158

By:

Derippe, Thibaud;
Fouliard, Sylvain;
Decleves, Xavier;
Mager, Donald E.

Publication type:

Article

Pharmacodynamic Models of Differential Bortezomib Signaling Across Several Cell Lines of Multiple Myeloma.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 3, p. 146, doi. 10.1002/psp4.12358

By:

Ramakrishnan, Vidya;
Mager, Donald E.

Publication type:

Article

Cell Signaling Model Connects Vorinostat Pharmacokinetics and Tumor Growth Response in Multiple Myeloma Xenografts.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2017, v. 6, n. 11, p. 756, doi. 10.1002/psp4.12246

By:

Nanavati, Charvi;
Ruszaj, Donna;
Mager, Donald E.

Publication type:

Article

In Memoriam: Darrell R. Abernethy 1949–2017.

Published in:

2018

By:

Greenblatt, David J.;
Mager, Donald E.;
Meibohm, Bernd;
Burckart, Gilbert J.

Publication type:

Obituary

Dynamic Model of Platelet Lifespan in Adult and Newborn Mice.

Published in:

FASEB Journal, 2013, v. 27, p. lb535, doi. 10.1096/fasebj.27.1_supplement.lb535

By:

Ait‐Oudhia, Sihem;
Mager, Donald E.;
Liu, Zhi‐Jian;
Veng‐Pedersen, Peter;
Sola‐Visner, Martha

Publication type:

Article

Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats.

Published in:

FASEB Journal, 2006, v. 20, n. 6, p. 631, doi. 10.1096/fj.05-5263com

By:

Mager, Donald E.;
Ruiqian Wan;
Brown, Martin;
Aiwu Cheng;
Wareski, Przemyslaw;
Abernethy, Darrell R.;
Mattson, Mark P.

Publication type:

Article

Immunosuppressant adherence in adult outpatient hematopoietic cell transplant recipients.

Published in:

Journal of Oncology Pharmacy Practice, 2024, v. 30, n. 2, p. 322, doi. 10.1177/10781552231171607

By:

McCune, Jeannine S;
Armenian, Saro H;
Nakamura, Ryotaro;
Shan, Haoyue;
Kanakry, Christopher G;
Mielcarek, Marco;
Gao, Wei;
Mager, Donald E

Publication type:

Article

Inter-Antibody Variability in the Clinical Pharmacokinetics of Monoclonal Antibodies Characterized Using Population Physiologically Based Pharmacokinetic Modeling.

Published in:

Antibodies (2073-4468), 2024, v. 13, n. 3, p. 54, doi. 10.3390/antib13030054

By:

Kumar, Mokshada;
Lanke, Sravani;
Yadav, Alka;
Ette, Mfonabasi;
Mager, Donald E.;
Shah, Dhaval K.

Publication type:

Article

PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation.

Published in:

2015

By:

Quach, Holly P;
Yang, Qi J;
Chow, Edwin C;
Mager, Donald E;
Hoi, Stacie Y;
Pang, K Sandy

Publication type:

journal article

PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation.

Published in:

British Journal of Pharmacology, 2015, v. 172, n. 14, p. 3611, doi. 10.1111/bph.13153

By:

Quach, Holly P;
Yang, Qi J;
Chow, Edwin C;
Mager, Donald E;
Hoi, Stacie Y;
Pang, K Sandy

Publication type:

Article

Population Pharmacodynamic Modelling of Aspirin- and Ibuprofen-Induced Inhibition of Platelet Aggregation in Healthy Subjects.

Published in:

Clinical Pharmacokinetics, 2008, v. 47, n. 2, p. 129, doi. 10.2165/00003088-200847020-00006

By:

Ying Hong;
Gengo, Fran M.;
Rainka, Michelle M.;
Bates, Vernice E.;
Mager, Donald E.

Publication type:

Article

Systems pharmacology and enhanced pharmacodynamic models for understanding antibody-based drug action and toxicity.

Published in:

mAbs (1942-0862), 2017, v. 9, n. 1, p. 15, doi. 10.1080/19420862.2016.1238995

By:

Ait-Oudhia, Sihem;
Ovacik, Meric Ayse;
Mager, Donald E.

Publication type:

Article

Comparison of sequential and joint nonlinear mixed effects modeling of tumor kinetics and survival following Durvalumab treatment in patients with metastatic urothelial carcinoma.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 4, p. 251, doi. 10.1007/s10928-023-09848-w

By:

Chen, Ting;
Zheng, Yanan;
Roskos, Lorin;
Mager, Donald E.

Publication type:

Article

Accelerating robust plausible virtual patient cohort generation by substituting ODE simulations with parameter space mapping.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 6, p. 625, doi. 10.1007/s10928-022-09826-8

By:

Derippe, Thibaud;
Fouliard, Sylvain;
Declèves, Xavier;
Mager, Donald E.

Publication type:

Article

Population-based meta-analysis of bortezomib exposure–response relationships in multiple myeloma patients.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 1, p. 77, doi. 10.1007/s10928-019-09670-3

By:

Zhang, Li;
Mager, Donald E.

Publication type:

Article

Boolean network modeling in systems pharmacology.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 1, p. 159, doi. 10.1007/s10928-017-9567-4

By:

Bloomingdale, Peter;
Nguyen, Van Anh;
Niu, Jin;
Mager, Donald E.

Publication type:

Article

Impact of dose selection on parameter estimation using a rapid binding approximation model of target-mediated drug disposition.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2011, v. 38, n. 2, p. 223, doi. 10.1007/s10928-010-9190-0

By:

Marathe, Anshu;
Van Wart, Scott;
Mager, Donald E.

Publication type:

Article

Rituximab dosing in hematological malignancies: an old question, revisited.

Published in:

2019

By:

Morcos, Peter N.;
Boehnke, Axel;
Valente, Nancy;
Mager, Donald E.

Publication type:

journal article

Quantitative structure–property relationships of camptothecins in humans.

Published in:

2010

By:

Xu C;
Barchet TM;
Mager DE;
Xu, Chao;
Barchet, Thomas M;
Mager, Donald E

Publication type:

journal article

Quantitative structure–property relationships of camptothecins in humans.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 325, doi. 10.1007/s00280-009-1037-2

By:

Chao Xu;
Barchet, Thomas M.;
Mager, Donald E.

Publication type:

Article

Tacrolimus Population Pharmacokinetics and Multiple CYP3A5 Genotypes in Black and White Renal Transplant Recipients.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 9, p. 1184, doi. 10.1002/jcph.1118

By:

Campagne, Olivia;
Mager, Donald E.;
Brazeau, Daniel;
Venuto, Rocco C.;
Tornatore, Kathleen M.

Publication type:

Article

In Memoriam: Darrell R. Abernethy, 1949–2017.

Published in:

2018

By:

Greenblatt, David J.;
Mager, Donald E.;
Meibohm, Bernd;
Burckart, Gilbert J.

Publication type:

Obituary

Influence of Meals and Glycemic Changes on QT Interval Dynamics.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 8, p. 966, doi. 10.1002/jcph.933

By:

Cirincione, Brenda;
Sager, Philip T.;
Mager, Donald E.

Publication type:

Article

Model-Based Evaluation of Exenatide Effects on the QT Interval in Healthy Subjects Following Continuous IV Infusion.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 8, p. 956, doi. 10.1002/jcph.882

By:

Cirincione, Brenda;
LaCreta, Frank;
Sager, Philip;
Mager, Donald E.

Publication type:

Article

A Limited Sampling Schedule to Estimate Mycophenolic Acid Area Under the Concentration-Time Curve in Hematopoietic Cell Transplantation Recipients.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1654, doi. 10.1177/0091270011429567

By:

Li, Hong;
Mager, Donald E.;
Bemer, Meagan J.;
Salinger, David H.;
Vicini, Paolo;
Sandmaier, Brenda M.;
Nash, Richard;
McCune, Jeannine S.

Publication type:

Article

Population Pharmacokinetic Model for a Novel Oral Hypoglycemic Formed In Vivo: Comparing the Use of Active Metabolite Data Alone Versus Using Data of Upstream and Downstream Metabolites.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 3, p. 404, doi. 10.1177/0091270010396373

By:

Kastrissios, Helen;
Walker, Joseph R.;
Carrothers, Timothy J.;
Kshirsagar, Smita;
Khariton, Tatiana;
Habtemariam, Bahru;
Mager, Donald E.;
Rohatagi, Shashank

Publication type:

Article

Bridging Pharmacology and Pathophysiology via Systems Modeling.

Published in:

Journal of Clinical Pharmacology, 2010, v. 50, n. 9, p. 56S, doi. 10.1177/0091270010377505

By:

D'Argenio, David Z.;
Mager, Donald E.

Publication type:

Article

Quantitative Structure-Property Relationships Modeling to Predict In Vitro and In Vivo Binding of Drugs to the Bile Sequestrant, Colesevelam (Welchol).

Published in:

Journal of Clinical Pharmacology, 2009, v. 49, n. 10, p. 1185, doi. 10.1177/0091270009340783

By:

Walker, Joseph R.;
Brown, Karen;
Rohatagi, Shashank;
Bathala, Mohinder S.;
Chao Xu;
Wickremasingha, Prachi K.;
Salazar, Daniel E.;
Mager, Donald E.

Publication type:

Article

Population Exposure-Response Modeling of Metformin in Patients With Type 2 Diabetes Mellitus.

Published in:

Journal of Clinical Pharmacology, 2008, v. 48, n. 6, p. 696, doi. 10.1177/0091270008316884

By:

Ying Hong;
Rohatagi, Shashank;
Habtemariam, Bahru;
Walker, Joseph R.;
Schwartz, Sherwyn L.;
Mager, Donald E.

Publication type:

Article

Dose Equivalency Evaluation of Major Corticosteroids: Pharmacokinetics and Cell Trafficking and Cortisol Dynamics.

Published in:

Journal of Clinical Pharmacology, 2003, v. 43, n. 11, p. 1216, doi. 10.1177/0091270003258651

By:

Mager, Donald E.;
Lin, Sheren X.;
Blum, Robert A.;
Lates, Christian D.;
Jusko, William J.

Publication type:

Article

Editorial: Model-informed decision making in the preclinical stages of pharmaceutical research and development.

Published in:

Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1184914

By:

Rui Li;
Craig, Morgan;
D’Argenio, David Z.;
Betts, Alison;
Mager, Donald E.;
Maurer, Tristan S.

Publication type:

Article

Immune regulatory adjuvant approach to mitigate subcutaneous immunogenicity of monoclonal antibodies.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1496169

By:

Jarvi, Nicole L.;
Patel, Manali;
Shetty, Krithika A.;
Nguyen, Nhan H.;
Grasperge, Brooke F.;
Mager, Donald E.;
Straubinger, Robert M.;
Balu-Iyer, Sathy V.

Publication type:

Article

Population Pharmacokinetic Model of N-acetylmannosamine (ManNAc) and N-acetylneuraminic acid (Neu5Ac) in Subjects with GNE Myopathy.

Published in:

Drugs in R&D, 2021, v. 21, n. 2, p. 189, doi. 10.1007/s40268-021-00343-6

By:

Van Wart, Scott;
Mager, Donald E.;
Bednasz, Cindy J.;
Huizing, Marjan;
Carrillo, Nuria

Publication type:

Article

Pharmacometrics and Systems Pharmacology 2030.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 1, p. 76, doi. 10.1002/cpt.1683

By:

Mentré, France;
Friberg, Lena E.;
Duffull, Stephen;
French, Jonathan;
Lauffenburger, Douglas A.;
Li, Lang;
Mager, Donald E.;
Sinha, Vikram;
Sobie, Eric;
Zhao, Ping

Publication type:

Article

Pharmacodynamic Drug–Drug Interactions.

Published in:

Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 6, p. 1395, doi. 10.1002/cpt.1434

By:

Niu, Jin;
Straubinger, Robert M.;
Mager, Donald E.

Publication type:

Article

Abciximab Pharmacodynamic Model with Neural Networks used to Integrate Sources of Patient Variability*.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 1, p. 60, doi. 10.1016/j.clpt.2003.09.008

By:

Urquidi-Macdonald, Mirna;
Mager, Donald E.;
Mascelli, Mary A.;
Frederick, Bart;
Freedman, Jane;
Fitzgerald, Desmond J.;
Kleiman, Neal S.;
Abernethy, Darrell R.

Publication type:

Article

Pharmacodynamic modeling of time-dependent transduction systems*.

Published in:

Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 3, p. 210, doi. 10.1067/mcp.2001.118244

By:

Mager, Donald E.;
Jusko, William J.

Publication type:

Article

Systems Pharmacology Modeling Identifies a Novel Treatment Strategy for Bortezomib-Induced Neuropathic Pain.

Published in:

Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.817236

By:

Bloomingdale, Peter;
Meregalli, Cristina;
Pollard, Kevin;
Canta, Annalisa;
Chiorazzi, Alessia;
Fumagalli, Giulia;
Monza, Laura;
Pozzi, Eleonora;
Alberti, Paola;
Ballarini, Elisa;
Oggioni, Norberto;
Carlson, Louise;
Liu, Wensheng;
Ghandili, Mehrnoosh;
Ignatowski, Tracey A.;
Lee, Kelvin P.;
Moore, Michael J.;
Cavaletti, Guido;
Mager, Donald E.

Publication type:

Article

The impact of tacrolimus exposure on extrarenal adverse effects in adult renal transplant recipients.

Published in:

British Journal of Clinical Pharmacology, 2019, v. 85, n. 3, p. 516, doi. 10.1111/bcp.13811

By:

Campagne, Olivia;
Mager, Donald E.;
Brazeau, Daniel;
Venuto, Rocco C.;
Tornatore, Kathleen M.

Publication type:

Article

Population pharmacokinetics of exenatide.

Published in:

British Journal of Clinical Pharmacology, 2017, v. 83, n. 3, p. 517, doi. 10.1111/bcp.13135

By:

Cirincione, Brenda;
Mager, Donald E.

Publication type:

Article

Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.

Published in:

British Journal of Clinical Pharmacology, 2012, v. 74, n. 2, p. 304, doi. 10.1111/j.1365-2125.2012.04198.x

By:

Zhao, Xiaochen;
Venkata, Swarajya Lakshmi Vattem;
Moaddel, Ruin;
Luckenbaugh, Dave A.;
Brutsche, Nancy E.;
Ibrahim, Lobna;
Zarate Jr, Carlos A.;
Mager, Donald E.;
Wainer, Irving W.

Publication type:

Article

Pharmaceutical Sciences: Insights and Observations from Academic Chairs and Vice Chairs.

Published in:

AAPS Journal, 2025, v. 27, n. 1, p. 1, doi. 10.1208/s12248-025-01026-9

By:

Ainslie, Kristy M.;
Bowers, Albert A;
Chichewicz, Robert H.;
Collier, Lara S.;
Doorn, Jonathan A.;
Frei, Christopher R.;
Ghandehari, Hamidreza;
Gibbs, Robert B.;
Lawrence, David S.;
Lee, Craig R.;
Mager, Donald E.;
Marker, Paul;
Schwendeman, Anna;
Suryanarayanan, Raj;
Williams III, Robert O.;
Xi, Yaguang;
Xie, Wen;
Xie, Xiang-Qun;
Zhu, Guizhi;
Nguyen, Juliane

Publication type:

Article

FOLFIRINOX Pharmacodynamic Interactions in 2D and 3D Pancreatic Cancer Cell Cultures.

Published in:

AAPS Journal, 2022, v. 24, n. 6, p. 1, doi. 10.1208/s12248-022-00752-8

By:

Allen-Coyle, Taylor J.;
Niu, Jin;
Welsch, Eva;
Conlon, Neil T.;
Garner, Weylon;
Clynes, Martin;
O'Sullivan, Finbarr;
Straubinger, Robert M.;
Mager, Donald E.;
Roche, Sandra

Publication type:

Article

Cluster Gauss–Newton and CellNOpt Parameter Estimation in a Small Protein Signaling Network of Vorinostat and Bortezomib Pharmacodynamics.

Published in:

AAPS Journal, 2021, v. 23, n. 6, p. 1, doi. 10.1208/s12248-021-00640-7

By:

Niu, Jin;
Nguyen, Van Anh;
Ghasemi, Mohammad;
Chen, Ting;
Mager, Donald E.

Publication type:

Article

Network-Based Systems Analysis Explains Sequence-Dependent Synergism of Bortezomib and Vorinostat in Multiple Myeloma.

Published in:

AAPS Journal, 2021, v. 23, n. 5, p. 1, doi. 10.1208/s12248-021-00622-9

By:

Nanavati, Charvi;
Mager, Donald E.

Publication type:

Article

Machine Learning Models for the Prediction of Chemotherapy-Induced Peripheral Neuropathy.

Published in:

Pharmaceutical Research, 2019, v. 36, n. 2, p. 1, doi. 10.1007/s11095-018-2562-7

By:

Bloomingdale, Peter;
Mager, Donald E.

Publication type:

Article

Interspecies Scaling of Receptor-Mediated Pharmacokinetics and Pharmacodynamics of Type I Interferons.

Published in:

Pharmaceutical Research, 2010, v. 27, n. 5, p. 920, doi. 10.1007/s11095-010-0098-6

By:

Kagan, Leonid;
Abraham, Anson K.;
Harrold, John M.;
Mager, Donald E.

Publication type:

Article