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Challenges with sirolimus experimental data to inform QSP model of post‐transplantation cyclophosphamide regimens.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 8, p. 1, doi. 10.1111/cts.70014
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- Publication type:
- Article
PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation.
- Published in:
- 2015
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- Publication type:
- journal article
PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D<sub>3</sub> in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation.
- Published in:
- British Journal of Pharmacology, 2015, v. 172, n. 14, p. 3611, doi. 10.1111/bph.13153
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- Publication type:
- Article
Abciximab Pharmacodynamic Model with Neural Networks used to Integrate Sources of Patient Variability<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 1, p. 60, doi. 10.1016/j.clpt.2003.09.008
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- Publication type:
- Article
Pharmacodynamic modeling of time-dependent transduction systems<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 3, p. 210, doi. 10.1067/mcp.2001.118244
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- Publication type:
- Article
Enantioselective pharmacokinetics of ( R)- and ( S)-ketamine after a 5-day infusion in patients with complex regional pain syndrome.
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- Chirality, 2011, v. 23, n. 2, p. 138, doi. 10.1002/chir.20890
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- Publication type:
- Article
Editorial: Model-informed decision making in the preclinical stages of pharmaceutical research and development.
- Published in:
- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1184914
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- Publication type:
- Article
Race-specific coregulatory and transcriptomic profiles associated with DNA methylation and androgen receptor in prostate cancer.
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- Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01323-6
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- Publication type:
- Article
Machine Learning Models for the Prediction of Chemotherapy-Induced Peripheral Neuropathy.
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 2, p. 1, doi. 10.1007/s11095-018-2562-7
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- Publication type:
- Article
Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer.
- Published in:
- 2020
- By:
- Publication type:
- journal article
In Memoriam: Darrell R. Abernethy 1949–2017.
- Published in:
- 2018
- By:
- Publication type:
- Obituary
Interspecies Scaling of Receptor-Mediated Pharmacokinetics and Pharmacodynamics of Type I Interferons.
- Published in:
- Pharmaceutical Research, 2010, v. 27, n. 5, p. 920, doi. 10.1007/s11095-010-0098-6
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- Publication type:
- Article
Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells.
- Published in:
- 2020
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- Publication type:
- journal article
Factor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti-factor VIII antibodies in hemophilia A mice.
- Published in:
- Biopharmaceutics & Drug Disposition, 2016, v. 37, n. 7, p. 409, doi. 10.1002/bdd.2023
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- Publication type:
- Article
Effects of hypertonic buffer composition on lymph node uptake and bioavailability of rituximab, after subcutaneous administration.
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- Biopharmaceutics & Drug Disposition, 2015, v. 36, n. 2, p. 115, doi. 10.1002/bdd.1925
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- Publication type:
- Article
Nonlinear pharmacokinetics of factor VIII and its phosphatidylinositol lipidic complex in hemophilia A mice.
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- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 3, p. 154, doi. 10.1002/bdd.1880
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- Publication type:
- Article
Population-based meta-analysis of furosemide pharmacokinetics.
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- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 2, p. 119, doi. 10.1002/bdd.1874
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- Publication type:
- Article
Population-based meta-analysis of hydrochlorothiazide pharmacokinetics.
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- Biopharmaceutics & Drug Disposition, 2013, v. 34, n. 9, p. 527, doi. 10.1002/bdd.1863
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- Publication type:
- Article
Population pharmacokinetics of tolvaptan in healthy subjects and patients with hyponatremia secondary to congestive heart failure or hepatic cirrhosis.
- Published in:
- Biopharmaceutics & Drug Disposition, 2013, v. 34, n. 6, p. 336, doi. 10.1002/bdd.1849
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- Publication type:
- Article
Integrated model for denosumab and ibandronate pharmacodynamics in postmenopausal women.
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- Biopharmaceutics & Drug Disposition, 2011, v. 32, n. 8, p. 471, doi. 10.1002/bdd.770
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- Publication type:
- Article
Pharmacodynamic profiles of ketamine (R)- and (S)- with 5-day inpatient infusion for the treatment of complex regional pain syndrome.
- Published in:
- 2010
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- Publication type:
- journal article
Pharmacodynamic Profiles of Ketamine (R)- and (S)- with 5-Day Inpatient Infusion for the Treatment of Complex Regional Pain Syndrome.
- Published in:
- Pain Physician, 2010, v. 13, n. 4, p. 379
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- Publication type:
- Article
Merging Systems Biology with Pharmacodynamics.
- Published in:
- Science Translational Medicine, 2012, v. 4, n. 126, p. 1, doi. 10.1126/scitranslmed.3003563
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- Publication type:
- Article
Population Pharmacokinetics of Tacrolimus in Transplant Recipients: What Did We Learn About Sources of Interindividual Variabilities?
- Published in:
- Journal of Clinical Pharmacology, 2019, v. 59, n. 3, p. 309, doi. 10.1002/jcph.1325
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- Publication type:
- Article
Tacrolimus Population Pharmacokinetics and Multiple CYP3A5 Genotypes in Black and White Renal Transplant Recipients.
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 9, p. 1184, doi. 10.1002/jcph.1118
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- Publication type:
- Article
In Memoriam: Darrell R. Abernethy, 1949–2017.
- Published in:
- 2018
- By:
- Publication type:
- Obituary
Immunosuppressant adherence in adult outpatient hematopoietic cell transplant recipients.
- Published in:
- Journal of Oncology Pharmacy Practice, 2024, v. 30, n. 2, p. 322, doi. 10.1177/10781552231171607
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- Publication type:
- Article
Comparison of sequential and joint nonlinear mixed effects modeling of tumor kinetics and survival following Durvalumab treatment in patients with metastatic urothelial carcinoma.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 4, p. 251, doi. 10.1007/s10928-023-09848-w
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- Publication type:
- Article
Accelerating robust plausible virtual patient cohort generation by substituting ODE simulations with parameter space mapping.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 6, p. 625, doi. 10.1007/s10928-022-09826-8
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- Publication type:
- Article
Population-based meta-analysis of bortezomib exposure–response relationships in multiple myeloma patients.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 1, p. 77, doi. 10.1007/s10928-019-09670-3
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- Publication type:
- Article
Boolean network modeling in systems pharmacology.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 1, p. 159, doi. 10.1007/s10928-017-9567-4
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- Publication type:
- Article
Impact of dose selection on parameter estimation using a rapid binding approximation model of target-mediated drug disposition.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2011, v. 38, n. 2, p. 223, doi. 10.1007/s10928-010-9190-0
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- Publication type:
- Article
Systems Pharmacology Modeling Identifies a Novel Treatment Strategy for Bortezomib-Induced Neuropathic Pain.
- Published in:
- Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.817236
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- Publication type:
- Article
Population pharmacokinetics of exenatide.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 3, p. 517, doi. 10.1111/bcp.13135
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- Publication type:
- Article
Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 74, n. 2, p. 304, doi. 10.1111/j.1365-2125.2012.04198.x
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- Publication type:
- Article
Population Pharmacokinetic Model of N-acetylmannosamine (ManNAc) and N-acetylneuraminic acid (Neu5Ac) in Subjects with GNE Myopathy.
- Published in:
- Drugs in R&D, 2021, v. 21, n. 2, p. 189, doi. 10.1007/s40268-021-00343-6
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- Publication type:
- Article
FOLFIRINOX Pharmacodynamic Interactions in 2D and 3D Pancreatic Cancer Cell Cultures.
- Published in:
- AAPS Journal, 2022, v. 24, n. 6, p. 1, doi. 10.1208/s12248-022-00752-8
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- Publication type:
- Article
Cluster Gauss–Newton and CellNOpt Parameter Estimation in a Small Protein Signaling Network of Vorinostat and Bortezomib Pharmacodynamics.
- Published in:
- AAPS Journal, 2021, v. 23, n. 6, p. 1, doi. 10.1208/s12248-021-00640-7
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- Publication type:
- Article
Network-Based Systems Analysis Explains Sequence-Dependent Synergism of Bortezomib and Vorinostat in Multiple Myeloma.
- Published in:
- AAPS Journal, 2021, v. 23, n. 5, p. 1, doi. 10.1208/s12248-021-00622-9
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- Publication type:
- Article
Pharmacokinetics and Toxicodynamics of Pralidoxime Effects on Paraoxon-Induced Respiratory Toxicity.
- Published in:
- Toxicological Sciences, 2010, v. 116, n. 2, p. 660, doi. 10.1093/toxsci/kfq152
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- Publication type:
- Article
The impact of tacrolimus exposure on extrarenal adverse effects in adult renal transplant recipients.
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 3, p. 516, doi. 10.1111/bcp.13811
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- Publication type:
- Article
Systems model identifies baseline cytokine concentrations as potential predictors of rheumatoid arthritis inflammatory response to biologics.
- Published in:
- British Journal of Pharmacology, 2022, v. 179, n. 16, p. 4063, doi. 10.1111/bph.15845
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- Publication type:
- Article
Population Pharmacodynamic Modelling of Aspirin- and Ibuprofen-Induced Inhibition of Platelet Aggregation in Healthy Subjects.
- Published in:
- Clinical Pharmacokinetics, 2008, v. 47, n. 2, p. 129, doi. 10.2165/00003088-200847020-00006
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- Publication type:
- Article
Pharmacometrics and Systems Pharmacology 2030.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 1, p. 76, doi. 10.1002/cpt.1683
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- Publication type:
- Article
Pharmacodynamic Drug–Drug Interactions.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 6, p. 1395, doi. 10.1002/cpt.1434
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- Publication type:
- Article
Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats.
- Published in:
- FASEB Journal, 2006, v. 20, n. 6, p. 631, doi. 10.1096/fj.05-5263com
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- Publication type:
- Article
Rituximab dosing in hematological malignancies: an old question, revisited.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Quantitative structure–property relationships of camptothecins in humans.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Quantitative structure–property relationships of camptothecins in humans.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 325, doi. 10.1007/s00280-009-1037-2
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- Publication type:
- Article
Quantitative systems pharmacology modeling of tumor heterogeneity in response to BH3‐mimetics using virtual tumors calibrated with cell viability assays.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 7, p. 1252, doi. 10.1002/psp4.13158
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- Publication type:
- Article