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Development and validation of an LC–MS/MS method for the determination of BLU-945, a fourth-generation EGFR tyrosine kinase inhibitor, in rat and mouse plasma: application to a pharmacokinetic study in rats.
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- Journal of Analytical Science & Technology, 2024, v. 15, n. 1, p. 1, doi. 10.1186/s40543-024-00452-2
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- Article
Physiologically Based Pharmacokinetic (PBPK) Modeling to Predict CYP3A-Mediated Drug Interaction between Saxagliptin and Nicardipine: Bridging Rat-to-Human Extrapolation.
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- Pharmaceutics, 2024, v. 16, n. 2, p. 280, doi. 10.3390/pharmaceutics16020280
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- Article
Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability.
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- Pharmaceutics, 2023, v. 15, n. 8, p. 2073, doi. 10.3390/pharmaceutics15082073
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- Article
Investigation of the factors responsible for the low oral bioavailability of alizarin using a sensitive LC‐MS/MS method: In vitro, in situ, and in vivo evaluations.
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- Drug Development Research, 2023, v. 84, n. 3, p. 579, doi. 10.1002/ddr.22047
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- Article
Investigation of N -Acetyltransferase 2-Mediated Drug Interactions of Amifampridine: In Vitro and In Vivo Evidence of Drug Interactions with Acetaminophen.
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- Pharmaceutics, 2023, v. 15, n. 5, p. 1471, doi. 10.3390/pharmaceutics15051471
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- Article
Recent Advances in Intranasal Liposomes for Drug, Gene, and Vaccine Delivery.
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- Pharmaceutics, 2023, v. 15, n. 1, p. 207, doi. 10.3390/pharmaceutics15010207
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- Article
Preparation and Characterization of Pazopanib Hydrochloride-Loaded Four-Component Self-Nanoemulsifying Drug Delivery Systems Preconcentrate for Enhanced Solubility and Dissolution.
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- Pharmaceutics, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/pharmaceutics14091875
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Bioanalysis of alpelisib using liquid chromatography–tandem mass spectrometry and application to pharmacokinetic study.
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- Journal of Analytical Science & Technology, 2022, v. 13, n. 1, p. 1, doi. 10.1186/s40543-022-00340-7
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- Article
Synthetic Peucedanocoumarin IV Prevents α-Synuclein Neurotoxicity in an Animal Model of Parkinson's Disease.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8618, doi. 10.3390/ijms23158618
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Development of an LC-MS/MS Method for ARV-110, a PROTAC Molecule, and Applications to Pharmacokinetic Studies.
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- Molecules, 2022, v. 27, n. 6, p. 1977, doi. 10.3390/molecules27061977
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- Article
Pharmacokinetics and Pharmacodynamics of Intranasal Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Nose-to-Brain Delivery.
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- Pharmaceutics, 2022, v. 14, n. 3, p. 572, doi. 10.3390/pharmaceutics14030572
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- Article
Synthesis and anti‐diabetic activity of novel biphenylsulfonamides as glucagon receptor antagonists.
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- Chemical Biology & Drug Design, 2021, v. 98, n. 5, p. 733, doi. 10.1111/cbdd.13928
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- Article
Effects of 1α,25-Dihydroxyvitamin D 3 on the Pharmacokinetics of Procainamide and Its Metabolite N-Acetylprocainamide, Organic Cation Transporter Substrates, in Rats with PBPK Modeling Approach.
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- Pharmaceutics, 2021, v. 13, n. 8, p. 1133, doi. 10.3390/pharmaceutics13081133
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Comparison of Pharmacokinetics and Anti-Pulmonary Fibrosis-Related Effects of Sulforaphane and Sulforaphane N -acetylcysteine.
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- Pharmaceutics, 2021, v. 13, n. 7, p. 958, doi. 10.3390/pharmaceutics13070958
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- Article
Pharmaceutical Formulations with P-Glycoprotein Inhibitory Effect as Promising Approaches for Enhancing Oral Drug Absorption and Bioavailability.
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- Pharmaceutics, 2021, v. 13, n. 7, p. 1103, doi. 10.3390/pharmaceutics13071103
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- Article
The Role of Processed Aloe vera Gel in Intestinal Tight Junction: An In Vivo and In Vitro Study.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6515, doi. 10.3390/ijms22126515
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- Article
Development of Non-Ethoxypropanoic Acid Type Cryptochrome Inhibitors with Circadian Molecular Clock-Enhancing Activity by Bioisosteric Replacement.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 6, p. 496, doi. 10.3390/ph14060496
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- Article
SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models.
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- EMBO Molecular Medicine, 2021, v. 13, n. 4, p. 1, doi. 10.15252/emmm.202013076
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Investigation of the Factors Responsible for the Poor Oral Bioavailability of Acacetin in Rats: Physicochemical and Biopharmaceutical Aspects.
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- Pharmaceutics, 2021, v. 13, n. 2, p. 175, doi. 10.3390/pharmaceutics13020175
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Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells.
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- Pharmaceutics, 2021, v. 13, n. 2, p. 181, doi. 10.3390/pharmaceutics13020181
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- Article
Development and Validation of a Bioanalytical LC-MS/MS Method for Simultaneous Determination of Sirolimus in Porcine Whole Blood and Lung Tissue and Pharmacokinetic Application with Coronary Stents.
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- Molecules, 2021, v. 26, n. 2, p. 425, doi. 10.3390/molecules26020425
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- Article
Brain Endothelial P-Glycoprotein Level Is Reduced in Parkinson's Disease via a Vitamin D Receptor-Dependent Pathway.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8538, doi. 10.3390/ijms21228538
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- Article
Differential Effects of 1α,25-Dihydroxyvitamin D 3 on the Expressions and Functions of Hepatic CYP and UGT Enzymes and Its Pharmacokinetic Consequences In Vivo.
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- Pharmaceutics, 2020, v. 12, n. 11, p. 1129, doi. 10.3390/pharmaceutics12111129
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Preparation of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Drug Delivery and the Effects of Preparation Parameters of Solvent Injection Method.
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- Molecules, 2020, v. 25, n. 20, p. 4781, doi. 10.3390/molecules25204781
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- Article
Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats.
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- Pharmaceutics, 2020, v. 12, n. 5, p. 397, doi. 10.3390/pharmaceutics12050397
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- Article
Development of 20(S)-Protopanaxadiol-Loaded SNEDDS Preconcentrate Using Comprehensive Phase Diagram for the Enhanced Dissolution and Oral Bioavailability.
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- Pharmaceutics, 2020, v. 12, n. 4, p. 362, doi. 10.3390/pharmaceutics12040362
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- Article
Determination of KD025 (SLx-2119), a Selective ROCK2 Inhibitor, in Rat Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Pharmacokinetic Application.
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- Molecules, 2020, v. 25, n. 6, p. 1369, doi. 10.3390/molecules25061369
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Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry.
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- Molecules, 2020, v. 25, n. 3, p. 531, doi. 10.3390/molecules25030531
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- Article
Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson's Disease.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5481, doi. 10.3390/ijms20215481
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- Article
Metabolic Stability of D-Allulose in Biorelevant Media and Hepatocytes: Comparison with Fructose and Erythritol.
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- Foods, 2019, v. 8, n. 10, p. 448, doi. 10.3390/foods8100448
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Preparation of Ondansetron Hydrochloride-Loaded Nanostructured Lipid Carriers Using Solvent Injection Method for Enhancement of Pharmacokinetic Properties.
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- Pharmaceutical Research, 2019, v. 36, n. 10, p. N.PAG, doi. 10.1007/s11095-019-2672-x
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BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47267-5
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- Article
Differential regulation of intestinal and hepatic CYP3A by 1α,25‐dihydroxyvitamin D<sub>3</sub>: Effects on in vivo oral absorption and disposition of buspirone in rats.
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- Drug Development Research, 2019, v. 80, n. 3, p. 333, doi. 10.1002/ddr.21505
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- Article
Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1772, doi. 10.3390/ijms20071772
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- Article
Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats.
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- Pharmaceutics, 2019, v. 11, n. 3, p. 108, doi. 10.3390/pharmaceutics11030108
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- Article
Development and Evaluation of Poorly Water-Soluble Celecoxib as Solid Dispersions Containing Nonionic Surfactants Using Fluidized-Bed Granulation.
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- Pharmaceutics, 2019, v. 11, n. 3, p. 136, doi. 10.3390/pharmaceutics11030136
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- Article
Synthesis of Gemcitabine-Threonine Amide Prodrug Effective on Pancreatic Cancer Cells with Improved Pharmacokinetic Properties.
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- Molecules, 2018, v. 23, n. 10, p. 2608, doi. 10.3390/molecules23102608
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- Article
Development and Evaluation of a Reconstitutable Dry Suspension to Improve the Dissolution and Oral Absorption of Poorly Water-Soluble Celecoxib.
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- Pharmaceutics, 2018, v. 10, n. 3, p. 140, doi. 10.3390/pharmaceutics10030140
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- Article
Determination of isoorientin levels in rat plasma after oral administration of Vaccinum bracteatum Thunb. methanol extract by high‐performance liquid chromatography‐tandem mass spectrometry.
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- Biomedical Chromatography, 2018, v. 32, n. 6, p. 1, doi. 10.1002/bmc.4188
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- Article
Simultaneous Determination of Procainamide and N-acetylprocainamide in Rat Plasma by Ultra-High-Pressure Liquid Chromatography Coupled with a Diode Array Detector and Its Application to a Pharmacokinetic Study in Rats.
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- Pharmaceutics, 2018, v. 10, n. 2, p. 41, doi. 10.3390/pharmaceutics10020041
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- Article
Simultaneous quantification of volitinib and gefitinib in rat plasma by HPLC–MS/MS for application to a pharmacokinetic study in rats.
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- Journal of Separation Science, 2017, v. 40, n. 19, p. 3782, doi. 10.1002/jssc.201700574
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- Article
Ginsenoside improves physicochemical properties and bioavailability of curcumin-loaded nanostructured lipid carrier.
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- Archives of Pharmacal Research, 2017, v. 40, n. 7, p. 864, doi. 10.1007/s12272-017-0930-1
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- Article
Quantification of mequitazine in human plasma by gas chromatography- quadrupole mass spectrometry and its application to a human pharmacokinetic study.
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- Biomedical Chromatography, 2016, v. 30, n. 4, p. 574, doi. 10.1002/bmc.3585
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Development and validation of a highly sensitive LC-MS/MS method for the determination of acacetin in human plasma and its application to a protein binding study.
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- Archives of Pharmacal Research, 2016, v. 39, n. 2, p. 213, doi. 10.1007/s12272-015-0697-1
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- Article
Contribution of CNT1 and ENT1 to ribavirin uptake in human hepatocytes.
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- Archives of Pharmacal Research, 2015, v. 38, n. 5, p. 904, doi. 10.1007/s12272-014-0437-y
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- Article
Recent bioanalytical methods for quantification of third-generation cephalosporins using HPLC and LC-MS(/MS) and their applications in pharmacokinetic studies.
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- Biomedical Chromatography, 2014, v. 28, n. 11, p. 1565, doi. 10.1002/bmc.3330
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- Article
Addition of amino acid moieties to lapatinib increases the anti-cancer effect via amino acid transporters.
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- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 1, p. 60, doi. 10.1002/bdd.1872
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- Article
Determination of cefdinir levels in rat plasma and urine by high-performance liquid chromatography-tandem mass spectrometry: application to pharmacokinetics after oral and intravenous administration of cefdinir.
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- Biomedical Chromatography, 2013, v. 27, n. 11, p. 1423, doi. 10.1002/bmc.2938
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Comparative effects of 1α-hydroxyvitamin D<sub>3</sub> and 1,25-dihydroxyvitamin D<sub>3</sub> on transporters and enzymes in fxr(+/+) and fxr(-/-) mice.
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- Biopharmaceutics & Drug Disposition, 2013, v. 34, n. 7, p. 402, doi. 10.1002/bdd.1856
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- Article
Effect of adjuvant on pharmacokinetics, organ distribution and humoral immunity of hepatitis b surface antigen after intramuscular injection to rats.
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- Archives of Pharmacal Research, 2012, v. 35, n. 9, p. 1621, doi. 10.1007/s12272-012-0913-1
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- Article