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Matrix Metalloproteinase-3 is Key Effector of TNF-α-Induced Collagen Degradation in Skin.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 20, p. 5234, doi. 10.3390/ijms20205234
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- Publication type:
- Article
An SCF<sup>FBXO28</sup> E3 Ligase Protects Pancreatic β-Cells from Apoptosis.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 4, p. 975, doi. 10.3390/ijms19040975
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- Publication type:
- Article
PHLPP1 deletion restores pancreatic β-cell survival and normoglycemia in the db/db mouse model of obesity-associated diabetes.
- Published in:
- Cell Death Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41420-022-00853-5
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- Publication type:
- Article
Beta cells in type 2 diabetes – a crucial contribution to pathogenesis.
- Published in:
- Diabetes, Obesity & Metabolism, 2008, v. 10, n. 5, p. 408, doi. 10.1111/j.1463-1326.2007.00718.x
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- Publication type:
- Article
The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25145-x
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- Publication type:
- Article
MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.
- Published in:
- Nature Medicine, 2014, v. 20, n. 4, p. 385, doi. 10.1038/nm.3482
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- Publication type:
- Article
The DPP-4 inhibitor linagliptin restores β-cell function and survival in human isolated islets through GLP-1 stabilization.
- Published in:
- 2013
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- Publication type:
- journal article
Reciprocal regulation of mTOR complexes in pancreatic islets from humans with type 2 diabetes.
- Published in:
- Diabetologia, 2017, v. 60, n. 4, p. 668, doi. 10.1007/s00125-016-4188-9
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- Article
MST1: a promising therapeutic target to restore functional beta cell mass in diabetes.
- Published in:
- Diabetologia, 2016, v. 59, n. 9, p. 1843, doi. 10.1007/s00125-016-3892-9
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- Publication type:
- Article
TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6.
- Published in:
- Diabetologia, 2014, v. 57, n. 8, p. 1645, doi. 10.1007/s00125-014-3249-1
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- Publication type:
- Article
Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes.
- Published in:
- Scientific Reports, 2017, p. 45319, doi. 10.1038/srep45319
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- Publication type:
- Article
Commentary: A Human Pluripotent Stem Cell-Based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
- Published in:
- Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.585922
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- Publication type:
- Article
Bone marrow mesenchymal stromal cells for diabetes therapy: touch, fuse, and fix?
- Published in:
- Stem Cell Research & Therapy, 2022, v. 13, n. 1, p. 1, doi. 10.1186/s13287-022-03028-2
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- Publication type:
- Article
Blockade but Not Overexpression of the Junctional Adhesion Molecule C Influences Virus-Induced Type 1 Diabetes in Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054675
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- Publication type:
- Article
Glucose-Stimulated Calcium Dynamics in Islets of Langerhans in Acute Mouse Pancreas Tissue Slices.
- Published in:
- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054638
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- Publication type:
- Article
Anti-Obesity Effect of Lactobacillus gasseri BNR17 in High-Sucrose Diet-Induced Obese Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054617
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- Publication type:
- Article
The Adipocytokine Nampt and Its Product NMN Have No Effect on Beta-Cell Survival but Potentiate Glucose Stimulated Insulin Secretion.
- Published in:
- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054106
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- Publication type:
- Article
Female Mice are Protected against High-Fat Diet Induced Metabolic Syndrome and Increase the Regulatory T Cell Population in Adipose Tissue.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046057
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- Publication type:
- Article
High Glucose Predisposes Gene Expression and ERK Phosphorylation to Apoptosis and Impaired Glucose-Stimulated Insulin Secretion via the Cytoskeleton.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044988
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- Publication type:
- Article
COUP-TFII Controls Mouse Pancreatic β-Cell Mass through GLP-1-β-Catenin Signaling Pathways.
- Published in:
- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030847
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- Publication type:
- Article
Deletion of the Mitochondrial Flavoprotein Apoptosis Inducing Factor (AIF) Inducesβ -Cell Apoptosis and Impairsβ-Cell Mass.
- Published in:
- PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004394
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- Publication type:
- Article
UCP-2 and UCP-3 Proteins Are Differentially Regulated in Pancreatic Beta-Cells.
- Published in:
- PLoS ONE, 2008, v. 3, n. 1, p. 1, doi. 10.1371/journal.pone.0001397
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- Publication type:
- Article
Sulfonylurea Induced β-Cell Apoptosis in Cultured Human Islets.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 1, p. 501, doi. 10.1210/jc.2004-0699
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- Publication type:
- Article
Sulfonylurea Induced β-Cell Apoptosis in Cultured Human Islets.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 1, p. 501, doi. 10.1210/jc.2004-0699
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- Publication type:
- Article
Inflammatory mediators and islet β-cell failure: a link between type 1 and type 2 diabetes.
- Published in:
- Journal of Molecular Medicine, 2003, v. 81, n. 8, p. 455, doi. 10.1007/s00109-003-0450-y
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- Publication type:
- Article
Enteroviral infections are not associated with type 2 diabetes.
- Published in:
- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1236574
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- Publication type:
- Article
Enteroviruses and T1D: Is It the Virus, the Genes or Both which Cause T1D.
- Published in:
- Microorganisms, 2020, v. 8, n. 7, p. 1017, doi. 10.3390/microorganisms8071017
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- Publication type:
- Article
Lung Surfactant Accelerates Skin Wound Healing: A Translational Study with a Randomized Clinical Phase I Study.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59394-5
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- Publication type:
- Article
GLP-2 Is Locally Produced From Human Islets and Balances Inflammation Through an Inter-Islet-Immune Cell Crosstalk.
- Published in:
- Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.697120
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- Publication type:
- Article
Possible Role of Interleukin-1β in Type 2 Diabetes Onset and Implications for Anti-inflammatory Therapy Strategies.
- Published in:
- PLoS Computational Biology, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.pcbi.1003798
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- Publication type:
- Article
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets.
- Published in:
- 2017
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- Publication type:
- journal article
Glucose and leptin induce apoptosis in human β-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases.
- Published in:
- FASEB Journal, 2008, v. 22, n. 6, p. 1905, doi. 10.1096/fj.07-101824
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- Publication type:
- Article
TCF7L2 splice variants have distinct effects on β-cell turnover and function.
- Published in:
- Human Molecular Genetics, 2011, v. 20, n. 10, p. 1906, doi. 10.1093/hmg/ddr072
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- Publication type:
- Article
Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes.
- Published in:
- PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0161834
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- Publication type:
- Article
Evaluation of Existing Methods for Human Blood mRNA Isolation and Analysis for Large Studies.
- Published in:
- PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161778
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- Publication type:
- Article
Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets.
- Published in:
- 2008
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- Publication type:
- journal article
Transcription Factor 7-Like 2 Regulates β-Cell Survival and Function in Human Pancreatic Islets.
- Published in:
- Diabetes, 2008, v. 57, n. 3, p. 645, doi. 10.2337/db07-0847
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- Publication type:
- Article
5-Lipoxygenase Is a Regulator of Insulin Secretion.
- Published in:
- Diabetes, 2007, v. 56, p. A410
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- Publication type:
- Article
The Anti-Inflammatory Cytokine Interleukin-1 Receptor Antagonist Protects from High Fat Diet Induced Diabetes by Maintaining PDX-1 Activity.
- Published in:
- Diabetes, 2007, v. 56, p. A27
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- Publication type:
- Article
Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets.
- Published in:
- 2006
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- Publication type:
- journal article
Low Concentration of Interleukin-1β Induces FLICE-Inhibitory Protein-Mediated β-Cell Proliferation in Human Pancreatic Islets.
- Published in:
- Diabetes, 2006, v. 55, n. 10, p. 2713, doi. 10.2337/db05-1430
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- Publication type:
- Article
Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1.
- Published in:
- 2006
- By:
- Publication type:
- journal article
Aging Correlates With Decreased ß-Cell Proliferative Capacity and Enhanced Sensitivity to Apoptosis.
- Published in:
- Diabetes, 2006, v. 55, n. 9, p. 2455, doi. 10.2337/db05-1586
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- Publication type:
- Article
Mechanisms of beta-cell death in type 2 diabetes.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Mechanisms of Β-Cell Death in Type 2 Diabetes.
- Published in:
- Diabetes, 2005, v. 54, p. S108, doi. 10.2337/diabetes.54.suppl_2.S108
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- Publication type:
- Article
Extracellular Matrix Protects Pancreatic β-Cells Against Apoptosis.
- Published in:
- Diabetes, 2004, v. 53, n. 8, p. 2034, doi. 10.2337/diabetes.53.8.2034
- By:
- Publication type:
- Article
Extracellular matrix protects pancreatic beta-cells against apoptosis: role of short- and long-term signaling pathways.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Glucose- and Interleukin-1β- Induced β-Cell Apoptosis Requires Ca<sup>2+</sup> Influx and Extracellular Signal-Regulated Kinase (ERK) ½ Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K<sup>+</sup> Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets
- Published in:
- Diabetes, 2004, v. 53, n. 7, p. 1706, doi. 10.2337/diabetes.53.7.1706
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- Publication type:
- Article
Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function.
- Published in:
- 2003
- By:
- Publication type:
- journal article