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Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.
Published in:
Journal of Molecular Recognition, 2016, v. 29, n. 6, p. 281, doi. 10.1002/jmr.2529
By:
- Krishnarjuna, Bankala;
- Lim, San Sui;
- Devine, Shane M.;
- Debono, Cael O.;
- Lam, Raymond;
- Chandrashekaran, Indu R.;
- Jaipuria, Garima;
- Yagi, Hiromasa;
- Atreya, Hanudatta S.;
- Scanlon, Martin J.;
- MacRaild, Christopher A.;
- Scammells, Peter J.;
- Norton, Raymond S.
Publication type:
Article
Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening.
Published in:
Australian Journal of Chemistry, 2013, v. 66, n. 12, p. 1530, doi. 10.1071/CH13266
By:
- Lim, San Sui;
- Debono, Cael O.;
- MacRaild, Christopher A.;
- Chandrashekaran, Indu R.;
- Dolezal, Olan;
- Anders, Robin F.;
- Simpson, Jamie S.;
- Scanlon, Martin J.;
- Devine, Shane M.;
- Scammells, Peter J.;
- Norton, Raymond S.
Publication type:
Article
Systematic Down-Selection of Repurposed Drug Candidates for COVID-19.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11851, doi. 10.3390/ijms231911851
By:
- MacRaild, Christopher A.;
- Mohammed, Muzaffar-Ur-Rehman;
- Faheem;
- Murugesan, Sankaranarayanan;
- Styles, Ian K.;
- Peterson, Amanda L.;
- Kirkpatrick, Carl M. J.;
- Cooper, Matthew A.;
- Palombo, Enzo A.;
- Simpson, Moana M.;
- Jain, Hardik A.;
- Agarwal, Vinti;
- McAuley, Alexander J.;
- Kumar, Anupama;
- Creek, Darren J.;
- Trevaskis, Natalie L.;
- Vasan, Seshadri S.
Publication type:
Article
Guiding the Immune Response to a Conserved Epitope in MSP2, an Intrinsically Disordered Malaria Vaccine Candidate.
Published in:
Vaccines, 2021, v. 9, n. 8, p. 855, doi. 10.3390/vaccines9080855
By:
- Seow, Jeffrey;
- Das, Sreedam C.;
- Morales, Rodrigo A. V.;
- Ataide, Ricardo;
- Krishnarjuna, Bankala;
- Silk, Mitchell;
- Chalmers, David K.;
- Richards, Jack;
- Anders, Robin F.;
- MacRaild, Christopher A.;
- Norton, Raymond S.
Publication type:
Article
Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
Published in:
ChemMedChem, 2019, v. 14, n. 5, p. 603, doi. 10.1002/cmdc.201800802
By:
- Akter, Mansura;
- Drinkwater, Nyssa;
- Devine, Shane M.;
- Drew, Simon C.;
- Krishnarjuna, Bankala;
- Debono, Cael O.;
- Wang, Geqing;
- Scanlon, Martin J.;
- Scammells, Peter J.;
- McGowan, Sheena;
- MacRaild, Christopher A.;
- Norton, Raymond S.
Publication type:
Article
Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2.
Published in:
Scientific Reports, 2016, p. 20613, doi. 10.1038/srep20613
By:
- Krishnarjuna, Bankala;
- Andrew, Dean;
- MacRaild, Christopher A.;
- Morales, Rodrigo A. V.;
- Beeson, James G.;
- Anders, Robin F.;
- Richards, Jack S.;
- Norton, Raymond S.
Publication type:
Article
A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum–infected red blood cell proteome.
Published in:
GigaScience, 2022, v. 11, p. 1, doi. 10.1093/gigascience/giac008
By:
- Siddiqui, Ghizal;
- De Paoli, Amanda;
- MacRaild, Christopher A;
- Sexton, Anna E;
- Boulet, Coralie;
- Shah, Anup D;
- Batty, Mitchell B;
- Schittenhelm, Ralf B;
- Carvalho, Teresa G;
- Creek, Darren J
Publication type:
Article
Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141729
By:
- Guy, Andrew J.;
- Irani, Vashti;
- MacRaild, Christopher A.;
- Anders, Robin F.;
- Norton, Raymond S.;
- Beeson, James G.;
- Richards, Jack S.;
- Ramsland, Paul A.
Publication type:
Article
Conformational Dynamics and Antigenicity in the Disordered Malaria Antigen Merozoite Surface Protein 2.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119899
By:
- MacRaild, Christopher A.;
- Zachrdla, Milan;
- Andrew, Dean;
- Krishnarjuna, Bankala;
- Nováček, Jiří;
- Žídek, Lukáš;
- Sklenář, Vladimír;
- Richards, Jack S.;
- Beeson, James G.;
- Anders, Robin F.;
- Norton, Raymond S.
Publication type:
Article
Molecular Insights into the Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and an Invasion-Inhibitory Peptide.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109674
By:
- Wang, Geqing;
- MacRaild, Christopher A.;
- Mohanty, Biswaranjan;
- Mobli, Mehdi;
- Cowieson, Nathan P.;
- Anders, Robin F.;
- Simpson, Jamie S.;
- McGowan, Sheena;
- Norton, Raymond S.;
- Scanlon, Martin J.
Publication type:
Article
RASP: rapid and robust backbone chemical shift assignments from protein structure.
Published in:
Journal of Biomolecular NMR, 2014, v. 58, n. 3, p. 155, doi. 10.1007/s10858-014-9813-7
By:
- MacRaild, Christopher;
- Norton, Raymond
Publication type:
Article
Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.92990
By:
- Giannangelo, Carlo;
- Challis, Matthew P.;
- Siddiqui, Ghizal;
- Edgar, Rebecca;
- Malcolm, Tess R.;
- Webb, Chaille T.;
- Drinkwater, Nyssa;
- Vinh, Natalie;
- Macraild, Christopher;
- Counihan, Natalie;
- Duffy, Sandra;
- Wittlin, Sergio;
- Devine, Shane M.;
- Avery, Vicky M.;
- De Koning-Ward, Tania;
- Scammells, Peter;
- McGowan, Sheena;
- Creek, Darren J.
Publication type:
Article
Lipid interactions modulate the structural and antigenic properties of the C-terminal domain of the malaria antigen merozoite surface protein 2.
Published in:
FEBS Journal, 2017, v. 284, n. 16, p. 2649, doi. 10.1111/febs.14135
By:
- Das, Sreedam C.;
- Morales, Rodrigo A.V.;
- Seow, Jeffrey;
- Krishnarjuna, Bankala;
- Dissanayake, Ravindu;
- Anders, Robin F.;
- MacRaild, Christopher A.;
- Norton, Raymond S.
Publication type:
Article
Use of Human Lung Tissue Models for Screening of Drugs against SARS-CoV-2 Infection.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 11, p. 2417, doi. 10.3390/v14112417
By:
- McAuley, Alexander J.;
- Jansen van Vuren, Petrus;
- Mohammed, Muzaffar-Ur-Rehman;
- Faheem;
- Goldie, Sarah;
- Riddell, Shane;
- Gödde, Nathan J.;
- Styles, Ian K.;
- Bruce, Matthew P.;
- Chahal, Simran;
- Keating, Stephanie;
- Blasdell, Kim R.;
- Tachedjian, Mary;
- O'Brien, Carmel M.;
- Singanallur, Nagendrakumar Balasubramanian;
- Viana, John Noel;
- Vashi, Aditya V.;
- Kirkpatrick, Carl M.;
- MacRaild, Christopher A.;
- Shah, Rohan M.
Publication type:
Article
Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.80813
By:
- Edgar, Rebecca C. S.;
- Siddiqui, Ghizal;
- Hjerrild, Katheryn;
- Malcolm, Tess R.;
- Vinh, Natalie B.;
- Webb, Chaille T.;
- Holmes, Clare;
- MacRaild, Christopher A.;
- Chernih, Hope C.;
- Suen, Willy W.;
- Counihan, Natalie A.;
- Creek, Darren J.;
- Scammells, Peter J.;
- McGowan, Sheena;
- de Koning-Ward, Tania F.
Publication type:
Article
Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope.
Published in:
Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0063-1
By:
- Krishnarjuna, Bankala;
- Sugiki, Toshihiko;
- Morales, Rodrigo A. V.;
- Seow, Jeffrey;
- Fujiwara, Toshimichi;
- Wilde, Karyn L.;
- Norton, Raymond S.;
- MacRaild, Christopher A.
Publication type:
Article
Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Published in:
Scientific Reports, 2015, p. 10103, doi. 10.1038/srep10103
By:
- Morales, Rodrigo A. V.;
- MacRaild, Christopher A.;
- Seow, Jeffrey;
- Krishnarjuna, Bankala;
- Drinkwater, Nyssa;
- Rouet, Romain;
- Anders, Robin F.;
- Christ, Daniel;
- McGowan, Sheena;
- Norton, Raymond S.
Publication type:
Article
Interaction of merozoite surface protein 2 with lipid membranes.
Published in:
FEBS Letters, 2019, v. 593, n. 3, p. 288, doi. 10.1002/1873-3468.13320
By:
- Lu, Chenghui;
- Zheng, Xue;
- Zhang, Wei;
- Zhao, Hongxin;
- MacRaild, Christopher A.;
- Norton, Raymond S.;
- Zhuang, Yonglong;
- Wang, Junfeng;
- Zhang, Xuecheng
Publication type:
Article
Applications of <sup>19</sup>F-NMR in Fragment-Based Drug Discovery.
Published in:
Molecules, 2016, v. 21, n. 7, p. 860, doi. 10.3390/molecules21070860
By:
- Norton, Raymond S.;
- Leung, Eleanor W. W.;
- Chandrashekaran, Indu R.;
- MacRaild, Christopher A.
Publication type:
Article
Modulation of the aggregation of an amyloidogenic sequence by flanking-disordered region in the intrinsically disordered antigen merozoite surface protein 2.
Published in:
European Biophysics Journal, 2019, v. 48, n. 1, p. 99, doi. 10.1007/s00249-018-1337-8
By:
- Zhang, Wei;
- Zhang, Jiahai;
- MacRaild, Christopher A.;
- Norton, Raymond S.;
- Anders, Robin F.;
- Zhang, Xuecheng
Publication type:
Article
Disordered epitopes as peptide vaccines.
Published in:
Peptide Science, 2018, v. 110, n. 3, p. 1, doi. 10.1002/pep2.24067
By:
- MacRaild, Christopher A.;
- Seow, Jeffrey;
- Das, Sreedam C.;
- Norton, Raymond S.
Publication type:
Article

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