Works by Macklin, Wendy B.

Results: 85

Complement inhibition rapidly blocks lesion extension and facilitates remyelination in neuromyelitis optica.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-02019-7

By:

Given, Katherine S;
Acker, Elizabeth G;
Macklin, Wendy B;
Carlin, Dan;
Owens, Gregory P.;
Bennett, Jeffrey L

Publication type:

Article

Cover Image.

Published in:

Journal of Neuroscience Research, 2021, v. 99, n. 3, p. i, doi. 10.1002/jnr.24785

By:

Bargagna‐Mohan, Paola;
Schultz, Gwendolyn;
Rheaume, Bruce;
Trakhtenberg, Ephraim F.;
Robson, Paul;
Pal‐Ghosh, Sonali;
Stepp, Mary Ann;
Given, Katherine S.;
Macklin, Wendy B.;
Mohan, Royce

Publication type:

Article

Corneal nonmyelinating Schwann cells illuminated by single‐cell transcriptomics and visualized by protein biomarkers.

Published in:

Journal of Neuroscience Research, 2021, v. 99, n. 3, p. 731, doi. 10.1002/jnr.24757

By:

Bargagna‐Mohan, Paola;
Schultz, Gwendolyn;
Rheaume, Bruce;
Trakhtenberg, Ephraim F.;
Robson, Paul;
Pal‐Ghosh, Sonali;
Stepp, Mary Ann;
Given, Katherine S.;
Macklin, Wendy B.;
Mohan, Royce

Publication type:

Article

Neuroprotection by central nervous system remyelination: Molecular, cellular, and functional considerations.

Published in:

Journal of Neuroscience Research, 2016, v. 94, n. 12, p. 1411, doi. 10.1002/jnr.23923

By:

Verden, Dylan;
Macklin, Wendy B.

Publication type:

Article

Astrocyte expression of a dominant‐negative interferon‐γ receptor.

Published in:

Journal of Neuroscience Research, 2005, v. 82, n. 1, p. 20, doi. 10.1002/jnr.20616

By:

Claudia Hindinger;
John M. Gonzalez;
Cornelia C. Bergmann;
Babette Fuss;
David R. Hinton;
Roscoe D. Atkinson;
Wendy B. Macklin;
Stephen A. Stohlman

Publication type:

Article

Oligodendrocyte development and myelination in GFP-transgenic zebrafish.

Published in:

Journal of Neuroscience Research, 2005, v. 81, n. 1, p. 1, doi. 10.1002/jnr.20516

By:

Mika Yoshida;
Wendy B. Macklin

Publication type:

Article

Myelin Proteolipid Protein Gene Expression in Jimpy and Jimpymsd Mice.

Published in:

Journal of Neurochemistry, 1988, v. 51, n. 2, p. 360, doi. 10.1111/j.1471-4159.1988.tb01047.x

By:

Gardinier, V.;
Macklin, Wendy B.

Publication type:

Article

Solid-Phase Immunoassays for Quantitation of Antibody to Bovine White Matter Proteolipid Apoprotein.

Published in:

Journal of Neurochemistry, 1982, v. 38, n. 2, p. 348, doi. 10.1111/j.1471-4159.1982.tb08635.x

By:

Macklin, Wendy B.;
Lees, Marjorie B.

Publication type:

Article

Production and Purification of Antibody to Bovine White Matter Proteolipid Apoprotein.

Published in:

Journal of Neurochemistry, 1981, v. 36, n. 1, p. 101, doi. 10.1111/j.1471-4159.1981.tb02383.x

By:

Macklin, Wendy B.;
Schwarting, Gerald A.;
Lees, Marjorie B.;
Cohen, Steven R.

Publication type:

Article

Evolution of a neuroprotective function of central nervous system myelin.

Published in:

Journal of Cell Biology, 2006, v. 172, n. 3, p. 469, doi. 10.1083/jcb.200509174

By:

Yin, Xinghua;
Baek, Rena C.;
Kirschner, Daniel A.;
Peterson, Alan;
Fujii, Yasuhisa;
Nave, Klaus-Armin;
Macklin, Wendy B.;
Trapp, Bruce D.

Publication type:

Article

Glutamate Stimulates Oligodendrocyte Progenitor Migration Mediated via an αv Integrin/Myelin Proteolipid Protein Complex.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 9, p. 2458, doi. 10.1523/JNEUROSCI.4054-05.2006

By:

Gudz, Tatyana I.;
Komuro, Hitoshi;
Macklin, Wendy B.

Publication type:

Article

Netrin-1 Is Required for the Normal Development of Spinal Cord Oligodendrocytes.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 7, p. 1913, doi. 10.1523/JNEUROSCI.3571-05.2006

By:

Hui-Hsin Tsai;
Macklin, Wendy B.;
Miller, Robert H.

Publication type:

Article

Proteolipid Protein Gene Mutation Induces Altered Ventilatory Response to Hypoxia in the Myelin-Deficient Rat.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 6, p. 2265, doi. 10.1523/JNEUROSCI.23-06-02265.2003

By:

Miller, Martha J.;
Haxhiu, Musa A.;
Georgiadis, Paraskevi;
Gudz, Tatyana I.;
Kangas, Cindy D.;
Macklin, Wendy B.

Publication type:

Article

Chronic experimental allergic encephalomyelitis produced by bovine proteolipid apoprotein: Immunological studies in rabbits.

Published in:

Annals of Neurology, 1983, v. 13, n. 3, p. 303, doi. 10.1002/ana.410130313

By:

Cambi, Franca;
Lees, Marjorie B.;
Williams, Rosemarie M.;
Macklin, Wendy B.

Publication type:

Article

Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression.

Published in:

FASEB Journal, 2013, v. 27, n. 5, p. 1868, doi. 10.1096/fj.12-224212

By:

Xiangyou Hu;
Schlanger, Rita;
Wanxia He;
Macklin, Wendy B.;
Riqiang Yan

Publication type:

Article

Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.

Published in:

FASEB Journal, 2008, v. 22, n. 8, p. 2970, doi. 10.1096/fj.08-106666

By:

Xiangyou Hu;
Wanxia He;
Diaconu, Claudiu;
Xiaoying Tang;
Kidd, Grahame J.;
Macklin, Wendy B.;
Trapp, Bruce D.;
Riqiang Yan

Publication type:

Article

Mutation in the Plp gene alters the electrophysiologic properties of neurons in the nts.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A916, doi. 10.1096/fasebj.21.6.a916

By:

Mayer, Cathy;
Wilson, Christopher;
Macklin, Wendy B.;
Miller, Martha J.

Publication type:

Article

p70S6 kinase regulates oligodendrocyte differentiation and is active in remyelinating lesions.

Published in:

Brain Communications, 2022, v. 4, n. 1, p. 1, doi. 10.1093/braincomms/fcac025

By:

Benardais, Karelle;
Ornelas, Isis M.;
Fauveau, Melissa;
Brown, Tanya L.;
Finseth, Lisbet T.;
Panic, Radmila;
Deboux, Cyrille;
Macklin, Wendy B.;
Wood, Teresa L.;
Nait-Oumesmar, Brahim

Publication type:

Article

The Myelin Brake: When Enough Is Enough.

Published in:

Science Signaling, 2010, v. 3, n. 140, p. 1, doi. 10.1126/scisignal.3140pe32

By:

Macklin, Wendy B.

Publication type:

Article

Digitized image analysis reveals diffuse abnormalities in normal-appearing white matter during acute experimental autoimmune encephalomyelitis.

Published in:

Journal of Neuroscience Research, 1998, v. 54, n. 3, p. 364, doi. 10.1002/(SICI)1097-4547(19981101)54:3<364::AID-JNR7>3.0.CO;2-#

By:

Kawczak, Julie A.;
Mathisen, Peter M.;
Drazba, Judith A.;
Fuss, Babette;
Macklin, Wendy B.;
Tuohy, Vincent K.

Publication type:

Article

Regulation of murine myelin proteolipid protein gene expression.

Published in:

Journal of Neuroscience Research, 1997, v. 50, n. 6, p. 917, doi. 10.1002/(SICI)1097-4547(19971215)50:6<917::AID-JNR2>3.0.CO;2-G

By:

Wight, Patricia A.;
Dobretsova, Anna;
Macklin, Wendy B.

Publication type:

Article

Expression of molecular chaperones and vesicle transport proteins in differentiating oligodendrocytes.

Published in:

Journal of Neuroscience Research, 1997, v. 50, n. 5, p. 769, doi. 10.1002/(SICI)1097-4547(19971201)50:5<769::AID-JNR13>3.0.CO;2-X

By:

Neri, Christine L.;
Duchala, Cynthia S.;
Macklin, Wendy B.

Publication type:

Article

The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 1, p. 132, doi. 10.1093/brain/aws284

By:

Hussain, Rashad;
Ghoumari, Abdel M.;
Bielecki, Bartosz;
Steibel, Jérôme;
Boehm, Nelly;
Liere, Philippe;
Macklin, Wendy B.;
Kumar, Narender;
Habert, René;
Mhaouty-Kodja, Sakina;
Tronche, François;
Sitruk-Ware, Regine;
Schumacher, Michael;
Ghandour, M. Said

Publication type:

Article

The Protein Tyrosine Phosphatase Shp2 Regulates Oligodendrocyte Differentiation and Early Myelination and Contributes to Timely Remyelination.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 787, doi. 10.1523/JNEUROSCI.2864-16.2017

By:

Harlow, Danielle E.;
Finseth, Lisbet T.;
Bourne, Jennifer N.;
Hickey, Sean P.;
Gould, Elizabeth A.;
Culp, Cecilia M.;
Ahrendsen, Jared T.;
Macklin, Wendy B.

Publication type:

Article

Loss of Tuberous Sclerosis Complex1 in Adult Oligodendrocyte Progenitor Cells Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 31, p. 7534, doi. 10.1523/JNEUROSCI.3454-16.2017

By:

McLane, Lauren E.;
Bourne, Jennifer N.;
Evangelou, Angelina V.;
Khandker, Luipa;
Macklin, Wendy B.;
Wood, Teresa L.

Publication type:

Article

Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 2, p. 397, doi. 10.1523/JNEUROSCI.2113-16.2017

By:

Hussain, Rashad;
Macklin, Wendy B.

Publication type:

Article

Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 48, p. 15875, doi. 10.1523/JNEUROSCI.0882-15.2015

By:

Jinxiang Dai;
Bercury, Kathryn K.;
Weilin Jin;
Macklin, Wendy B.

Publication type:

Article

Myelin Proteolipid Protein Complexes with αv Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 34, p. 12018, doi. 10.1523/JNEUROSCI.5151-14.2015

By:

Harlow, Danielle E.;
Saul, Katherine E.;
Hitoshi Komuro;
Macklin, Wendy B.

Publication type:

Article

Oligl Function Is Required for Oligodendrocyte Differentiation in the Mouse Brain.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 10, p. 4386, doi. 10.1523/JNEUROSCI.4962-14.2015

By:

Jinxiang Dai;
Bercury, Kathryn K.;
Ahrendsen, Jared T.;
Macklin, Wendy B.

Publication type:

Article

Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 13, p. 4466, doi. 10.1523/JNEUROSCI.4314-13.2014

By:

Bercury, Kathryn K.;
JinXiang Dai;
Sachs, Hilary H.;
Ahrendsen, Jared T.;
Wood, Teresa L.;
Macklin, Wendy B.

Publication type:

Article

Mammalian Target of Rapamycin Promotes Oligodendrocyte Differentiation, Initiation and Extent of CNS Myelination.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 13, p. 4453, doi. 10.1523/JNEUROSCI.4311-13.2014

By:

Wahl, Stacey E.;
McLane, Lauren E.;
Bercury, Kathryn K.;
Macklin, Wendy B.;
Wood, Teresa L.

Publication type:

Article

Expression of Proteolipid Protein Gene in Spinal Cord Stem Cells and Early Oligodendrocyte Progenitor Cells Is Dispensable for Normal Cell Migration and Myelination.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 4, p. 1333, doi. 10.1523/JNEUROSCI.2477-13.2014

By:

Harlow, Danielle E.;
Saul, Katherine E.;
Culp, Cecilia M.;
Vesely, Elisa M.;
Macklin, Wendy B.

Publication type:

Article

Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination.

Published in:

Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0428-6

By:

Yiting Liu;
Given, Katherine S.;
Harlow, Danielle E.;
Matschulat, Adeline M.;
Macklin, Wendy B.;
Bennett, Jeffrey L.;
Owens, Gregory P.

Publication type:

Article

Intravital assessment of myelin molecular order with polarimetric multiphoton microscopy.

Published in:

Scientific Reports, 2016, p. 31685, doi. 10.1038/srep31685

By:

Turcotte, Raphaël;
Rutledge, Danette J.;
Bélanger, Erik;
Dill, Dorothy;
Macklin, Wendy B.;
Côté, Daniel C.

Publication type:

Article

Bace1 modulates myelination in the central and peripheral nervous system.

Published in:

Nature Neuroscience, 2006, v. 9, n. 12, p. 1520, doi. 10.1038/nn1797

By:

Xiangyou Hu;
Hicks, Caitlin W.;
Wanxia He;
Wong, Philip;
Macklin, Wendy B.;
Trapp, Bruce D.;
Riqiang Yan

Publication type:

Article

Electroblot analysis of the myelin proteolipid protein.

Published in:

Journal of Neuroscience Research, 1982, v. 7, n. 1, p. 1, doi. 10.1002/jnr.490070102

By:

Macklin, Wendy B.;
Braun, Peter E.;
Lees, Marjorie B.

Publication type:

Article

Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors.

Published in:

Annals of Neurology, 2013, v. 73, n. 5, p. 637, doi. 10.1002/ana.23860

By:

Dutta, Ranjan;
Chomyk, Anthony M.;
Chang, Ansi;
Ribaudo, Michael V.;
Deckard, Sadie A.;
Doud, Mary K.;
Edberg, Dale D.;
Bai, Brian;
Li, Michael;
Baranzini, Sergio E.;
Fox, Robert J.;
Staugaitis, Susan M.;
Macklin, Wendy B.;
Trapp, Bruce D.

Publication type:

Article

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients.

Published in:

Annals of Neurology, 2006, v. 59, n. 3, p. 478

By:

Ranjan Dutta;
Jennifer McDonough;
Xinghua Yin;
John Peterson;
Ansi Chang;
Thalia Torres;
Tatyana Gudz;
Wendy B. Macklin;
David A. Lewis;
Robert J. Fox;
Richard Rudick;
Karoly Mirnics;
Bruce D. Trapp

Publication type:

Article

Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2019, v. 39, n. 6, p. 1005, doi. 10.1177/0271678X17750761

By:

Orfila, James E.;
Grewal, Himmat;
Dietz, Robert M.;
Strnad, Frank;
Shimizu, Takeru;
Moreno, Myriam;
Schroeder, Christian;
Yonchek, Joan;
Rodgers, Krista M.;
Dingman, Andra;
Bernard, Timothy J.;
Quillinan, Nidia;
Macklin, Wendy B.;
Traystman, Richard J.;
Herson, Paco S.

Publication type:

Article

Reversal of non-hydroxy : α-hydroxy galactosylceramide ratio and unstable myelin in transgenic mice overexpressing UDP-galactose : ceramide galactosyltransferase.

Published in:

Journal of Neurochemistry, 2005, v. 94, n. 2, p. 469, doi. 10.1111/j.1471-4159.2005.03221.x

By:

Fewou, Simon N.;
Büssow, Heinrich;
Schaeren-Wiemers, Nicole;
Vanier, Marie T.;
Macklin, Wendy B.;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

CONTROL OF THE MYELIN PROTEOLIPID PROTEIN GENE BY RNA STABILITY IN CULTURED CELLS.

Published in:

1999

By:

Mallon, Barbara S.;
Macklin, Wendy B.

Publication type:

Abstract

Mutations in the Myelin Proteolipid Protein Gene Alter Oligodendrocyte Gene Expression in Jimpy and Jimpymsd Mice.

Published in:

Journal of Neurochemistry, 1991, v. 56, n. 1, p. 163, doi. 10.1111/j.1471-4159.1991.tb02576.x

By:

Macklin, Wendy B.;
Gardinier, Minnetta V.;
Obeso, Zaida O.;
King, Kit D.;
Wight, Patricia A.

Publication type:

Article

Gene induction in mature oligodendrocytes with a PLP-tTA mouse line.

Published in:

Genesis: The Journal of Genetics & Development, 2012, v. 50, n. 5, p. 424, doi. 10.1002/dvg.20808

By:

Inamura, Naoko;
Sugio, Shouta;
Macklin, Wendy B.;
Tomita, Koichi;
Tanaka, Kenji F.;
Ikenaka, Kazuhiro

Publication type:

Article

Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia.

Published in:

Microbiome, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40168-021-01165-z

By:

Vicentini, Fernando A.;
Keenan, Catherine M.;
Wallace, Laurie E.;
Woods, Crystal;
Cavin, Jean-Baptiste;
Flockton, Amanda R.;
Macklin, Wendy B.;
Belkind-Gerson, Jaime;
Hirota, Simon A.;
Sharkey, Keith A.

Publication type:

Article

Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination.

Published in:

Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00057

By:

Bruce, Kimberley D.;
Gorkhali, Sachi;
Given, Katherine;
Coates, Alison M.;
Boyle, Kristen E.;
Macklin, Wendy B.;
Eckel, Robert H.

Publication type:

Article

Marjorie Lees (1923-2012).

Published in:

2012

By:

Macklin, Wendy B.

Publication type:

Obituary

Long-lasting masculinizing effects of postnatal androgens on myelin governed by the brain androgen receptor.

Published in:

PLoS Genetics, 2017, v. 13, n. 11, p. 1, doi. 10.1371/journal.pgen.1007049

By:

Abi Ghanem, Charly;
Degerny, Cindy;
Hussain, Rashad;
Liere, Philippe;
Pianos, Antoine;
Tourpin, Sophie;
Habert, René;
Macklin, Wendy B.;
Schumacher, Michael;
Ghoumari, Abdel M.

Publication type:

Article

Early myelination involves the dynamic and repetitive ensheathment of axons which resolves through a low and consistent stabilization rate.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.82111

By:

Almeida, Adam R.;
Macklin, Wendy B.

Publication type:

Article

Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.78202

By:

Jewett, Cayla E.;
McCurdy, Bailey L.;
O'Toole, Eileen T.;
Stemm-Wolf, Alexander J.;
Given, Katherine S.;
Lin, Carrie H.;
Olsen, Valerie;
Martin, Whitney;
Reinholdt, Laura;
Espinosa, Joaquín M.;
Sullivan, Kelly D.;
Macklin, Wendy B.;
Prekeris, Rytis;
Pearson, Chad G.

Publication type:

Article

Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00514-7

By:

Ryan, Duncan P.;
Gould, Elizabeth A.;
Seedorf, Gregory J.;
Masihzadeh, Omid;
Abman, Steven H.;
Vijayaraghavan, Sukumar;
Macklin, Wendy B.;
Restrepo, Diego;
Shepherd, Douglas P.

Publication type:

Article