Works matching AU Macklin, Wendy B.

Results: 86

Early myelination involves the dynamic and repetitive ensheathment of axons which resolves through a low and consistent stabilization rate.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.82111

By:

Almeida, Adam R.;
Macklin, Wendy B.

Publication type:

Article

Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination.

Published in:

Journal of Neuroscience, 2020, v. 40, n. 15, p. 2993, doi. 10.1523/JNEUROSCI.1434-18.2020

By:

Musah, Aminat S.;
Brown, Tanya L.;
Jeffries, Marisa A.;
Quan Shang;
Hirokazu Hashimoto;
Evangelou, Angelina V.;
Kowalski, Alison;
Batish, Mona;
Macklin, Wendy B.;
Wood, Teresa L.

Publication type:

Article

The Protein Tyrosine Phosphatase Shp2 Regulates Oligodendrocyte Differentiation and Early Myelination and Contributes to Timely Remyelination.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 787, doi. 10.1523/JNEUROSCI.2864-16.2017

By:

Harlow, Danielle E.;
Finseth, Lisbet T.;
Bourne, Jennifer N.;
Hickey, Sean P.;
Gould, Elizabeth A.;
Culp, Cecilia M.;
Ahrendsen, Jared T.;
Macklin, Wendy B.

Publication type:

Article

Loss of Tuberous Sclerosis Complex1 in Adult Oligodendrocyte Progenitor Cells Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 31, p. 7534, doi. 10.1523/JNEUROSCI.3454-16.2017

By:

McLane, Lauren E.;
Bourne, Jennifer N.;
Evangelou, Angelina V.;
Khandker, Luipa;
Macklin, Wendy B.;
Wood, Teresa L.

Publication type:

Article

Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 2, p. 397, doi. 10.1523/JNEUROSCI.2113-16.2017

By:

Hussain, Rashad;
Macklin, Wendy B.

Publication type:

Article

Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 48, p. 15875, doi. 10.1523/JNEUROSCI.0882-15.2015

By:

Jinxiang Dai;
Bercury, Kathryn K.;
Weilin Jin;
Macklin, Wendy B.

Publication type:

Article

Myelin Proteolipid Protein Complexes with αv Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 34, p. 12018, doi. 10.1523/JNEUROSCI.5151-14.2015

By:

Harlow, Danielle E.;
Saul, Katherine E.;
Hitoshi Komuro;
Macklin, Wendy B.

Publication type:

Article

Oligl Function Is Required for Oligodendrocyte Differentiation in the Mouse Brain.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 10, p. 4386, doi. 10.1523/JNEUROSCI.4962-14.2015

By:

Jinxiang Dai;
Bercury, Kathryn K.;
Ahrendsen, Jared T.;
Macklin, Wendy B.

Publication type:

Article

The three SoxC proteins—Sox4, Sox11 and Sox12—exhibit overlapping expression patterns and molecular properties.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 9, p. 3101, doi. 10.1093/nar/gkn162

By:

Dy, Peter;
Penzo-Méndez, Alfredo;
Wang, Hongzhe;
Pedraza, Carlos E.;
Macklin, Wendy B.;
Lefebvre, Véronique

Publication type:

Article

Constitutively Active Akt Induces Enhanced Myelination in the CNS.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 28, p. 7174, doi. 10.1523/JNEUROSCI.0150-08.2008

By:

Flores, Ana I.;
Narayanan, S. Priyadarshini;
Morse, Emily N.;
Shick, H. Elizabeth;
Xinghua Yin;
Kidd, Grahame;
Avila, Robin L.;
Kirschner, Daniel A.;
Macklin, Wendy B.

Publication type:

Article

Rescuing qkv Dysmyelination by a Single Isoform of the Selective RNA-Binding Protein QKI.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 44, p. 20

By:

Lixia Zhao;
Donghua Tian;
Mingjing Xia;
Macklin, Wendy B.;
Yue Feng

Publication type:

Article

Glutamate Stimulates Oligodendrocyte Progenitor Migration Mediated via an αv Integrin/Myelin Proteolipid Protein Complex.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 9, p. 2458, doi. 10.1523/JNEUROSCI.4054-05.2006

By:

Gudz, Tatyana I.;
Komuro, Hitoshi;
Macklin, Wendy B.

Publication type:

Article

Netrin-1 Is Required for the Normal Development of Spinal Cord Oligodendrocytes.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 7, p. 1913, doi. 10.1523/JNEUROSCI.3571-05.2006

By:

Hui-Hsin Tsai;
Macklin, Wendy B.;
Miller, Robert H.

Publication type:

Article

Proteolipid Protein Gene Mutation Induces Altered Ventilatory Response to Hypoxia in the Myelin-Deficient Rat.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 6, p. 2265, doi. 10.1523/JNEUROSCI.23-06-02265.2003

By:

Miller, Martha J.;
Haxhiu, Musa A.;
Georgiadis, Paraskevi;
Gudz, Tatyana I.;
Kangas, Cindy D.;
Macklin, Wendy B.

Publication type:

Article

Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2019, v. 39, n. 6, p. 1005, doi. 10.1177/0271678X17750761

By:

Orfila, James E.;
Grewal, Himmat;
Dietz, Robert M.;
Strnad, Frank;
Shimizu, Takeru;
Moreno, Myriam;
Schroeder, Christian;
Yonchek, Joan;
Rodgers, Krista M.;
Dingman, Andra;
Bernard, Timothy J.;
Quillinan, Nidia;
Macklin, Wendy B.;
Traystman, Richard J.;
Herson, Paco S.

Publication type:

Article

A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation.

Published in:

PLoS Genetics, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pgen.1002063

By:

Zhao, Lihong;
Spassieva, Stefka D.;
Jucius, Thomas J.;
Shultz, Leonard D.;
Shick, H. Elizabeth;
Macklin, Wendy B.;
Hannun, Yusuf A.;
Obeid, Lina M.;
Ackerman, Susan L.

Publication type:

Article

Oligodendrocyte Progenitor Cell Proliferation and Fate after White Matter Stroke in Juvenile and Adult Mice.

Published in:

Developmental Neuroscience, 2018, v. 40, n. 5/6, p. 601, doi. 10.1159/000496200

By:

Dingman, Andra L.;
Rodgers, Krista M.;
Dietz, Robert M.;
Hickey, Sean P.;
Frazier, Alexandra P.;
Clevenger, Amy C.;
Yonchek, Joan C.;
Traystman, Richard J.;
Macklin, Wendy B.;
Herson, Paco S.

Publication type:

Article

mTORC2 Loss in Oligodendrocyte Progenitor Cells Results in Regional Hypomyelination in the Central Nervous System.

Published in:

Journal of Neuroscience, 2023, v. 43, n. 4, p. 540, doi. 10.1523/JNEUROSCI.0010-22.2022

By:

Dahl, Kristin D.;
Almeida, Adam R.;
Hathaway, Hannah A.;
Bourne, Jennifer;
Brown, Tanya L.;
Finseth, Lisbet T.;
Wood, Teresa L.;
Macklin, Wendy B.

Publication type:

Article

Excitable Axonal Domains Adapt to Sensory Deprivation in the Olfactory System.

Published in:

Journal of Neuroscience, 2022, v. 42, n. 8, p. 1491, doi. 10.1523/JNEUROSCI.0305-21.2021

By:

George, Nicholas M.;
Polese, Arianna Gentile;
Merle, Laetitia;
Macklin, Wendy B.;
Restrepo, Diego

Publication type:

Article

mTOR Signaling Regulates Metabolic Function in Oligodendrocyte Precursor Cells and Promotes Efficient Brain Remyelination in the Cuprizone Model.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 40, p. 8321, doi. 10.1523/JNEUROSCI.1377-20.2021

By:

Jeffries, Marisa A.;
McLane, Lauren E.;
Khandker, Luipa;
Mather, Marie L.;
Evangelou, Angelina V.;
Kantak, Divyangi;
Bourne, Jennifer N.;
Macklin, Wendy B.;
Wood, Teresa L.

Publication type:

Article

PAK1 Positively Regulates Oligodendrocyte Morphology and Myelination.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 9, p. 1864, doi. 10.1523/JNEUROSCI.0229-20.2021

By:

Brown, Tanya L.;
Hirokazu Hashimoto;
Finseth, Lisbet T.;
Wood, Teresa L.;
Macklin, Wendy B.

Publication type:

Article

Structure and Expression of the Mouse Myelin Proteolipid Protein Genea.

Published in:

Annals of the New York Academy of Sciences, 1990, v. 605, n. 1, p. 183, doi. 10.1111/j.1749-6632.1990.tb42392.x

By:

MACKLIN, WENDY B.;
GARDINIER, MINNETTA V.;
OBESO, ZAIDA O.

Publication type:

Article

A novel myelin protein zero transgenic zebrafish designed for rapid readout of in vivo myelination.

Published in:

Glia (0894-1491), 2019, v. 67, n. 4, p. 650, doi. 10.1002/glia.23559

By:

Preston, Marnie A.;
Finseth, Lisbet T.;
Bourne, Jennifer N.;
Macklin, Wendy B.

Publication type:

Article

Distinct patterns of glia repair and remyelination in antibody‐mediated demyelination models of multiple sclerosis and neuromyelitis optica.

Published in:

Glia (0894-1491), 2018, v. 66, n. 12, p. 2575, doi. 10.1002/glia.23512

By:

Liu, Yiting;
Given, Katherine S.;
Owens, Gregory P.;
Macklin, Wendy B.;
Bennett, Jeffrey L.

Publication type:

Article

Juvenile striatal white matter is resistant to ischemia-induced damage.

Published in:

Glia (0894-1491), 2016, v. 64, n. 11, p. 1972, doi. 10.1002/glia.23036

By:

Ahrendsen, Jared T.;
Grewal, Himmat S.;
Hickey, Sean P.;
Culp, Cecilia M.;
Gould, Elizabeth A.;
Shimizu, Takeru;
Strnad, Frank A.;
Traystman, Richard J.;
Herson, Paco S.;
Macklin, Wendy B.

Publication type:

Article

Zebrafish as a model to investigate CNS myelination.

Published in:

Glia (0894-1491), 2015, v. 63, n. 2, p. 177, doi. 10.1002/glia.22755

By:

Preston, Marnie A.;
Macklin, Wendy B.

Publication type:

Article

Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.

Published in:

Glia (0894-1491), 2014, v. 62, n. 12, p. 2096, doi. 10.1002/glia.22729

By:

Dai, JinXiang;
Bercury, Kathryn K.;
Macklin, Wendy B.

Publication type:

Article

Dynamics of ten-eleven translocation hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation.

Published in:

Glia (0894-1491), 2014, v. 62, n. 6, p. 914, doi. 10.1002/glia.22649

By:

Zhao, Xianghui;
Dai, Jinxiang;
Ma, Yue;
Mi, Yajing;
Cui, Daxiang;
Ju, Gong;
Macklin, Wendy B.;
Jin, Weilin

Publication type:

Article

Production, characterization, and efficient transfection of highly pure oligodendrocyte precursor cultures from mouse embryonic neural progenitors.

Published in:

Glia (0894-1491), 2008, v. 56, n. 12, p. 1339, doi. 10.1002/glia.20702

By:

Pedraza, Carlos E.;
Monk, Raymond;
Lei, Junying;
Hao, Qi;
Macklin, Wendy B.

Publication type:

Article

Dominant‐negative β1 integrin mice have region‐specific myelin defects accompanied by alterations in MAPK activity.

Published in:

Glia (0894-1491), 2006, v. 53, n. 8, p. 836, doi. 10.1002/glia.20343

By:

Karen K. Lee;
Yves De Repentigny;
Ron Saulnier;
Peter Rippstein;
Wendy B. Macklin;
Rashmi Kothary

Publication type:

Article

Expression of a dominant negative IFN-?receptor on mouse oligodendrocytes.

Published in:

Glia (0894-1491), 2005, v. 51, n. 1, p. 22, doi. 10.1002/glia.20182

By:

John M. Gonzlez;
Cornelia C. Bergmann;
Babette Fuss;
David R. Hinton;
Cindy Kangas;
Wendy B. Macklin;
Stephen A. Stohlman

Publication type:

Article

Hyperphosphorylation and insolubility of a-synuclein in transgenic mouse oligodendrocytes.

Published in:

EMBO Reports, 2002, v. 3, n. 6, p. 583, doi. 10.1093/embo-reports/kvf109

By:

Kahle, Philipp J.;
Neumann, Manuela;
Ozmen, Laurence;
Müller, Veronika;
Jacobsen, Helmut;
Spooren, Will;
Fuss, Babette;
Mallon, Barbara;
Macklin, Wendy B.;
Fujiwara, Hideo;
Hasegawa, Masato;
Iwatsubo, Takeshi;
Kretzschmar, Hans A.;
Haass, Christian

Publication type:

Article

Evolution of a neuroprotective function of central nervous system myelin.

Published in:

Journal of Cell Biology, 2006, v. 172, n. 3, p. 469, doi. 10.1083/jcb.200509174

By:

Yin, Xinghua;
Baek, Rena C.;
Kirschner, Daniel A.;
Peterson, Alan;
Fujii, Yasuhisa;
Nave, Klaus-Armin;
Macklin, Wendy B.;
Trapp, Bruce D.

Publication type:

Article

Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination.

Published in:

Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0428-6

By:

Yiting Liu;
Given, Katherine S.;
Harlow, Danielle E.;
Matschulat, Adeline M.;
Macklin, Wendy B.;
Bennett, Jeffrey L.;
Owens, Gregory P.

Publication type:

Article

Cover Image.

Published in:

Journal of Neuroscience Research, 2021, v. 99, n. 3, p. i, doi. 10.1002/jnr.24785

By:

Bargagna‐Mohan, Paola;
Schultz, Gwendolyn;
Rheaume, Bruce;
Trakhtenberg, Ephraim F.;
Robson, Paul;
Pal‐Ghosh, Sonali;
Stepp, Mary Ann;
Given, Katherine S.;
Macklin, Wendy B.;
Mohan, Royce

Publication type:

Article

Corneal nonmyelinating Schwann cells illuminated by single‐cell transcriptomics and visualized by protein biomarkers.

Published in:

Journal of Neuroscience Research, 2021, v. 99, n. 3, p. 731, doi. 10.1002/jnr.24757

By:

Bargagna‐Mohan, Paola;
Schultz, Gwendolyn;
Rheaume, Bruce;
Trakhtenberg, Ephraim F.;
Robson, Paul;
Pal‐Ghosh, Sonali;
Stepp, Mary Ann;
Given, Katherine S.;
Macklin, Wendy B.;
Mohan, Royce

Publication type:

Article

Neuroprotection by central nervous system remyelination: Molecular, cellular, and functional considerations.

Published in:

Journal of Neuroscience Research, 2016, v. 94, n. 12, p. 1411, doi. 10.1002/jnr.23923

By:

Verden, Dylan;
Macklin, Wendy B.

Publication type:

Article

Astrocyte expression of a dominant‐negative interferon‐γ receptor.

Published in:

Journal of Neuroscience Research, 2005, v. 82, n. 1, p. 20, doi. 10.1002/jnr.20616

By:

Claudia Hindinger;
John M. Gonzalez;
Cornelia C. Bergmann;
Babette Fuss;
David R. Hinton;
Roscoe D. Atkinson;
Wendy B. Macklin;
Stephen A. Stohlman

Publication type:

Article

Oligodendrocyte development and myelination in GFP-transgenic zebrafish.

Published in:

Journal of Neuroscience Research, 2005, v. 81, n. 1, p. 1, doi. 10.1002/jnr.20516

By:

Mika Yoshida;
Wendy B. Macklin

Publication type:

Article

The Actin Cytoskeleton in Myelinating Cells.

Published in:

2020

By:

Brown, Tanya L.;
Macklin, Wendy B.

Publication type:

Literature Review

Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 13, p. 4466, doi. 10.1523/JNEUROSCI.4314-13.2014

By:

Bercury, Kathryn K.;
JinXiang Dai;
Sachs, Hilary H.;
Ahrendsen, Jared T.;
Wood, Teresa L.;
Macklin, Wendy B.

Publication type:

Article

Mammalian Target of Rapamycin Promotes Oligodendrocyte Differentiation, Initiation and Extent of CNS Myelination.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 13, p. 4453, doi. 10.1523/JNEUROSCI.4311-13.2014

By:

Wahl, Stacey E.;
McLane, Lauren E.;
Bercury, Kathryn K.;
Macklin, Wendy B.;
Wood, Teresa L.

Publication type:

Article

Expression of Proteolipid Protein Gene in Spinal Cord Stem Cells and Early Oligodendrocyte Progenitor Cells Is Dispensable for Normal Cell Migration and Myelination.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 4, p. 1333, doi. 10.1523/JNEUROSCI.2477-13.2014

By:

Harlow, Danielle E.;
Saul, Katherine E.;
Culp, Cecilia M.;
Vesely, Elisa M.;
Macklin, Wendy B.

Publication type:

Article

Longitudinal Near-Infrared Imaging of Myelination.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 7, p. 2381, doi. 10.1523/JNEUROSCI.2698-10.2011

By:

Changning Wang;
Chunying Wu;
Popescu, Daniela C.;
Junqing Zhu;
Macklin, Wendy B.;
Miller, Robert H.;
Yanming Wang

Publication type:

Article

Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 21, p. 6860, doi. 10.1523/JNEUROSCI.0232-09.2009

By:

Narayanan, S. Priyadarshini;
Flores, Ana I.;
Feng Wang;
Macklin, Wendy B.

Publication type:

Article

Golli Myelin Basic Proteins Regulate Oligodendroglial Progenitor Cell Migration through Voltage-Gated Ca2+ Influx.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 20, p. 6663, doi. 10.1523/JNEUROSCI.5806-08.2009

By:

Paez, Pablo M.;
Fulton, Daniel J.;
Spreuer, Vilma;
Handley, Vance;
Campagnoni, Celia W.;
Macklin, Wendy B.;
Colwell, Christopher;
Campagnoni, Anthony T.

Publication type:

Article

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients.

Published in:

Annals of Neurology, 2006, v. 59, n. 3, p. 478

By:

Ranjan Dutta;
Jennifer McDonough;
Xinghua Yin;
John Peterson;
Ansi Chang;
Thalia Torres;
Tatyana Gudz;
Wendy B. Macklin;
David A. Lewis;
Robert J. Fox;
Richard Rudick;
Karoly Mirnics;
Bruce D. Trapp

Publication type:

Article

Production and Purification of Antibody to Bovine White Matter Proteolipid Apoprotein.

Published in:

Journal of Neurochemistry, 1981, v. 36, n. 1, p. 101, doi. 10.1111/j.1471-4159.1981.tb02383.x

By:

Macklin, Wendy B.;
Schwarting, Gerald A.;
Lees, Marjorie B.;
Cohen, Steven R.

Publication type:

Article

Complement inhibition rapidly blocks lesion extension and facilitates remyelination in neuromyelitis optica.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-02019-7

By:

Given, Katherine S;
Acker, Elizabeth G;
Macklin, Wendy B;
Carlin, Dan;
Owens, Gregory P.;
Bennett, Jeffrey L

Publication type:

Article

Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia.

Published in:

Microbiome, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40168-021-01165-z

By:

Vicentini, Fernando A.;
Keenan, Catherine M.;
Wallace, Laurie E.;
Woods, Crystal;
Cavin, Jean-Baptiste;
Flockton, Amanda R.;
Macklin, Wendy B.;
Belkind-Gerson, Jaime;
Hirota, Simon A.;
Sharkey, Keith A.

Publication type:

Article