Works by Mackay, Charles R.

Results: 68

Diet, gut microbiota and immune responses.

Published in:

Nature Immunology, 2011, v. 12, n. 1, p. 5, doi. 10.1038/ni0111-5

By:

Maslowski, Kendle M;
Mackay, Charles R

Publication type:

Article

Moving targets: cell migration inhibitors as new anti-inflammatory therapies.

Published in:

Nature Immunology, 2008, v. 9, n. 9, p. 988, doi. 10.1038/ni.f.210

By:

Mackay, Charles R

Publication type:

Article

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.

Published in:

Nature Immunology, 2006, v. 7, n. 3, p. 274, doi. 10.1038/ni1310

By:

Jeffrey, Kate L.;
Brummer, Tilman;
Rolph, Michael S.;
Liu, Sue M.;
Callejas, Nuria A.;
Grumont, Raelene J.;
Gillieron, Corine;
Mackay, Fabienne;
Grey, Shane;
Camps, Montserrat;
Rommel, Christian;
Gerondakis, Steve D.;
Mackay, Charles R.

Publication type:

Article

Chemokines: immunology's high impact factors.

Published in:

Nature Immunology, 2001, v. 2, n. 2, p. 95, doi. 10.1038/84298

By:

Mackay, Charles R.

Publication type:

Article

Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies.

Published in:

Nature Biotechnology, 2006, v. 24, n. 10, p. 1279, doi. 10.1038/nbt1248

By:

Hyun Lee;
Zahra, David;
Vogelzang, Alexis;
Newton, Rebecca;
Thatcher, Jenny;
Quan, Annie;
So, Trina;
Zwirner, Jörg;
Koentgen, Frank;
Padkjær, Søren B.;
Mackay, Fabienne;
Whitfeld, Peter L.;
Mackay, Charles R.

Publication type:

Article

Chemokine receptor CXCR7 antagonism ameliorates cardiac and renal fibrosis induced by mineralocorticoid excess.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-75789-0

By:

Wang, Bing H.;
Robert, Remy;
Marques, Francine Z.;
Rajapakse, Niwanthi;
Kiriazis, Helen;
Mackay, Charles R.;
Kaye, David M.

Publication type:

Article

CXCR3⁺CCR5⁺ T cells and autoimmune diseases: guilty as charged?

Published in:

2014

By:

Mackay, Charles R

Publication type:

journal article

CXCR3+CCR5+ T cells and autoimmune diseases: guilty as charged?

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3682, doi. 10.1172/JCI77837

By:

Mackay, Charles R.

Publication type:

Article

The adipocyte fatty acid--binding protein aP2 is required in allergic airway inflammation.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 8, p. 2183, doi. 10.1172/JCI24767

By:

Shum, Bennett O. V.;
Mackay, Charles R.;
Gorgun, Cem Z.;
Frost, Melinda J.;
Kumar, Rakesh K.;
Hotamisligil, Gökhan S.;
Rolph, Michael S.

Publication type:

Article

Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model.

Published in:

Autoimmunity, 2015, v. 48, n. 7, p. 460, doi. 10.3109/08916934.2015.1031888

By:

Atkinson, Sara M.;
Nansen, Anneline;
Usher, Pernille A.;
Sondergaard, Bodil-Cecilie;
Mackay, Charles R.;
Friedrichsen, Birgitte;
Chang, Chih-Chuan;
Tang, Renhong;
Skov, Søren;
Haase, Claus;
Hornum, Lars

Publication type:

Article

Gαs‐coupled GPCRs GPR65 and GPR174. Downers for immune responses.

Published in:

Immunology & Cell Biology, 2018, v. 96, n. 4, p. 341, doi. 10.1111/imcb.12027

By:

Robert, Remy;
Mackay, Charles R.

Publication type:

Article

The Question of Method in Ethics Consultation: The IRB Frontier.

Published in:

American Journal of Bioethics, 2001, v. 1, n. 4, p. 50, doi. 10.1162/152651601317139432

By:

MacKay, Charles R.

Publication type:

Article

The Metabolic Sensor GPR43 Receptor Plays a Role in the Control of Klebsiella pneumoniae Infection in the Lung.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00142

By:

Galvão, Izabela;
Tavares, Luciana P.;
Corrêa, Renan O.;
Fachi, José Luís;
Rocha, Vitor Melo;
Rungue, Marcela;
Garcia, Cristiana C.;
Cassali, Geovanni;
Ferreira, Caroline M.;
Martins, Flaviano S.;
Oliveira, Sergio C.;
Mackay, Charles R.;
Teixeira, Mauro M.;
Vinolo, Marco Aurélio R.;
Vieira, Angélica T.

Publication type:

Article

BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice.

Published in:

European Journal of Immunology, 2014, v. 44, n. 4, p. 983, doi. 10.1002/eji.201344186

By:

Mariño, Eliana;
Walters, Stacey N.;
Villanueva, Jeanette E.;
Richards, James L.;
Mackay, Charles R.;
Grey, Shane T.

Publication type:

Article

G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163750

By:

Kamp, Marjon E.;
Shim, Raymond;
Nicholls, Alyce J.;
Oliveira, Ana Carolina;
Mason, Linda J.;
Binge, Lauren;
Mackay, Charles R.;
Wong, Connie H. Y.

Publication type:

Article

Human CXCR1 knock-in mice infer functional expression of a murine ortholog.

Published in:

Journal of Leukocyte Biology, 2023, v. 114, n. 4, p. 373, doi. 10.1093/jleuko/qiad085

By:

Fahimi, Farnaz;
Alam, Md Jahangir;
Ang, Caroline;
Adhyatma, Galih Prakasa;
Xie, Liang;
Mackay, Charles R;
Robert, Remy

Publication type:

Article

Neutrophil subsets and their differential roles in viral respiratory diseases.

Published in:

Journal of Leukocyte Biology, 2022, v. 111, n. 6, p. 1159, doi. 10.1002/JLB.1MR1221-345R

By:

Zhang, Yuning;
Wang, Quanbo;
Mackay, Charles R;
Ng, Lai Guan;
Kwok, Immanuel

Publication type:

Article

Targeting NLRP3 and Staphylococcal pore‐forming toxin receptors in human‐induced pluripotent stem cell‐derived macrophages.

Published in:

Journal of Leukocyte Biology, 2020, v. 108, n. 3, p. 967, doi. 10.1002/JLB.4MA0420-497R

By:

Chow, Seong H.;
Deo, Pankaj;
Yeung, Amy T. Y.;
Kostoulias, Xenia P.;
Jeon, Yusun;
Gao, Mei‐Ling;
Seidi, Azadeh;
Olivier, Françios Alwyn Benson;
Sridhar, Sushmita;
Nethercott, Cara;
Cameron, David;
Robertson, Avril A. B.;
Robert, Remy;
Mackay, Charles R.;
Traven, Ana;
Jin, Zi‐Bing;
Hale, Christine;
Dougan, Gordon;
Peleg, Anton Y.;
Naderer, Thomas

Publication type:

Article

Influence of angiotensin II on the gut microbiome: modest effects in comparison to experimental factors.

Published in:

Cardiovascular Research, 2024, v. 120, n. 10, p. 1155, doi. 10.1093/cvr/cvae062

By:

Muralitharan, Rikeish R;
Nakai, Michael E;
Snelson, Matthew;
Zheng, Tenghao;
Dinakis, Evany;
Xie, Liang;
Jama, Hamdi;
Paterson, Madeleine;
Shihata, Waled;
Wassef, Flavia;
Vinh, Antony;
Drummond, Grant R;
Kaye, David M;
Mackay, Charles R;
Marques, Francine Z

Publication type:

Article

Dietary Fiber and Microbiota Metabolite Receptors Enhance Cognition and Alleviate Disease in the 5xFAD Mouse Model of Alzheimer's Disease.

Published in:

Journal of Neuroscience, 2023, v. 43, n. 37, p. 6460, doi. 10.1523/JNEUROSCI.0724-23.2023

By:

Yichen Zhou;
Liang Xie;
Schröder, Jan;
Schuster, Iona S.;
Nakai, Michael;
Guizhi Sun;
Sun, Yu B. Y.;
Mariño, Eliana;
Degli-Esposti, Mariapia A.;
Marques, Francine Z.;
Grubman, Alexandra;
Polo, Jose M.;
Mackay, Charles R.

Publication type:

Article

A Butyrate-Yielding Dietary Supplement Prevents Acute Alcoholic Liver Injury by Modulating Nrf2-Mediated Hepatic Oxidative Stress and Gut Microbiota.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 17, p. 9420, doi. 10.3390/ijms25179420

By:

Xu, Qi;
Guo, Mei;
Wang, Haidi;
Liu, Haitao;
Wei, Yunbo;
Wang, Xiao;
Mackay, Charles R.;
Wang, Quanbo

Publication type:

Article

New Study of the IRB System.

Published in:

Kennedy Institute of Ethics Journal, 1992, v. 2, n. 3, p. 283, doi. 10.1353/ken.0.0245

By:

MACKAY, CHARLES R.

Publication type:

Article

The functional plasticity of T cell subsets.

Published in:

2009

By:

Bluestone, Jeffrey A.;
Mackay, Charles R.;
O'Shea, John J.;
Stockinger, Brigitta

Publication type:

research

Follicular B helper T cells in antibody responses and autoimmunity.

Published in:

2005

By:

Vinuesa, Carola G.;
Tangye, Stuart G.;
Moser, Bernhard;
Mackay, Charles R.

Publication type:

journal article

The Role of Follicular Helper T Cell Molecules and Environmental Influences in Autoantibody Production and Progression to Inflammatory Arthritis in Mice.

Published in:

Arthritis & Rheumatology, 2016, v. 68, n. 4, p. 1026, doi. 10.1002/art.39481

By:

Chevalier, Nina;
Macia, Laurence;
Tan, Jian K.;
Mason, Linda J.;
Robert, Remy;
Thorburn, Alison N.;
Wong, Connie H. Y.;
Tsai, Louis M.;
Bourne, Katherine;
Brink, Robert;
Yu, Di;
Mackay, Charles R.

Publication type:

Article

A Role for Gut Microbiota and the Metabolite-Sensing Receptor GPR43 in a Murine Model of Gout.

Published in:

Arthritis & Rheumatology, 2015, v. 67, n. 6, p. 1646, doi. 10.1002/art.39107

By:

Vieira, Angélica T.;
Macia, Laurence;
Galvão, Izabela;
Martins, Flaviano S.;
Canesso, Maria Cecília C.;
Amaral, Flávio A.;
Garcia, Cristiana C.;
Maslowski, Kendle M.;
De Leon, Ellen;
Shim, Doris;
Nicoli, Jacques R.;
Harper, Jacquie L.;
Teixeira, Mauro M.;
Mackay, Charles R.

Publication type:

Article

An acetate‐yielding diet imprints an immune and anti‐microbial programme against enteric infection.

Published in:

Clinical & Translational Immunology, 2021, v. 10, n. 1, p. 1, doi. 10.1002/cti2.1233

By:

Yap, Yu Anne;
McLeod, Keiran H;
McKenzie, Craig I;
Gavin, Patrick G;
Davalos‐Salas, Mercedes;
Richards, James L;
Moore, Robert J;
Lockett, Trevor J;
Clarke, Julie M;
Eng, Vik Ven;
Pearson, Jaclyn S;
Hamilton‐Williams, Emma E;
Mackay, Charles R;
Mariño, Eliana

Publication type:

Article

A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184278

By:

Robert, Remy;
Juglair, Laurent;
Lim, Ee X.;
Ang, Caroline;
Wang, Carl J. H.;
Ebert, Gregor;
Dolezal, Olan;
Mackay, Charles R.

Publication type:

Article

Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation.

Published in:

Microbiome, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40168-021-01193-9

By:

Bell, Kirstine J.;
Saad, Sonia;
Tillett, Bree J.;
McGuire, Helen M.;
Bordbar, Sara;
Yap, Yu Anne;
Nguyen, Long T.;
Wilkins, Marc R.;
Corley, Susan;
Brodie, Shannon;
Duong, Sussan;
Wright, Courtney J.;
Twigg, Stephen;
de St Groth, Barbara Fazekas;
Harrison, Leonard C.;
Mackay, Charles R.;
Gurzov, Esteban N.;
Hamilton-Williams, Emma E.;
Mariño, Eliana

Publication type:

Article

Neutrophils in cancer—unresolved questions.

Published in:

SCIENCE CHINA Life Sciences, 2021, v. 64, n. 11, p. 1829, doi. 10.1007/s11427-020-1853-4

By:

Ng, Melissa S. F.;
Tan, Leonard;
Wang, Quanbo;
Mackay, Charles R.;
Ng, Lai Guan

Publication type:

Article

New avenues for anti-inflammatory therapy.

Published in:

Nature Medicine, 2002, v. 8, n. 2, p. 117, doi. 10.1038/nm0202-117

By:

Mackay, Charles R.

Publication type:

Article

Cyclophosphamide treatment induces rejection of established P815 mastocytoma by enhancing CD4 priming and intratumoral infiltration of P1E/H-2Kd-specific CD8+ T cells.

Published in:

International Journal of Cancer, 2014, v. 134, n. 12, p. 2841, doi. 10.1002/ijc.28617

By:

Rahir, Gwendoline;
Wathelet, Nathalie;
Hanoteau, Aurélie;
Henin, Coralie;
Oldenhove, Guillaume;
Galuppo, Adrien;
Lanaya, Hanane;
Colau, Didier;
Mackay, Charles R.;
den Eynde, Benoit;
Moser, Muriel

Publication type:

Article

Indole-3-Acetic Acid Esterified with Waxy, Normal, and High-Amylose Maize Starches: Comparative Study on Colon-Targeted Delivery and Intestinal Health Impact.

Published in:

Nutrients, 2024, v. 16, n. 20, p. 3446, doi. 10.3390/nu16203446

By:

Gong, Qian;
Qu, Xinyan;
Zhao, Yisheng;
Zhang, Xingjing;
Cao, Shuhua;
Wang, Xiao;
Song, Yingying;
Mackay, Charles R.;
Wang, Quanbo

Publication type:

Article

Indole-3-acetic acid ameliorates dextran sulfate sodium-induced colitis via the ERK signaling pathway.

Published in:

Archives of Pharmacal Research, 2024, v. 47, n. 3, p. 288, doi. 10.1007/s12272-024-01488-z

By:

Qu, Xinyan;
Song, Yingying;
Li, Qingjun;
Xu, Qi;
Li, Yanru;
Zhang, Huimin;
Cheng, Xuemei;
Mackay, Charles R.;
Wang, Quanbo;
Liu, Wei

Publication type:

Article

Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale.

Published in:

Liver International, 2024, v. 44, n. 10, p. 2834, doi. 10.1111/liv.16060

By:

Zhang, Weici;
Al Tekreeti, Taha;
Leung, Patrick S. C.;
Tsuneyama, Koichi;
Dhillon, Harleen;
Rojas, Manuel;
Heuer, Luke S.;
Ridgway, William M.;
Ansari, Aftab A.;
Young, Howard A.;
Mackay, Charles R.;
Gershwin, M. Eric

Publication type:

Article

The nutrition-gut microbiome-physiology axis and allergic diseases.

Published in:

Immunological Reviews, 2017, v. 278, n. 1, p. 277, doi. 10.1111/imr.12556

By:

McKenzie, Craig;
Tan, Jian;
Macia, Laurence;
Mackay, Charles R.

Publication type:

Article

Microbial influences on epithelial integrity and immune function as a basis for inflammatory diseases.

Published in:

Immunological Reviews, 2012, v. 245, n. 1, p. 164, doi. 10.1111/j.1600-065X.2011.01080.x

By:

Macia, Laurence;
Thorburn, Alison N.;
Binge, Lauren C.;
Marino, Eliana;
Rogers, Kate E.;
Maslowski, Kendle M.;
Vieira, Angélica T.;
Kranich, Jan;
Mackay, Charles R.

Publication type:

Article

Functional roles for C5a receptors in sepsis.

Published in:

Nature Medicine, 2008, v. 14, n. 5, p. 551, doi. 10.1038/nm1753

By:

Rittirsch, Daniel;
Flierl, Michael A.;
Nadeau, Brian A.;
Day, Danielle E.;
Huber-Lang, Markus;
Mackay, Charles R.;
Zetoune, Firas S.;
Gerard, Norma P.;
Cianflone, Katherine;
Köhl, Jörg;
Gerard, Craig;
Sarma, J. Vidya;
Ward, Peter A.

Publication type:

Article

Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms.

Published in:

FASEB Journal, 2019, v. 33, n. 11, p. 11894, doi. 10.1096/fj.201901080R

By:

Felizardo, Raphael J. F.;
de Almeida, Danilo C.;
Pereira, Rafael L.;
Watanabe, Ingrid K. M.;
Doimo, Nayara T. S.;
Ribeiro, Willian R.;
Cenedeze, Marcos A.;
Hiyane, Meire I.;
Amano, Mariane T.;
Braga, Tárcio T.;
Ferreira, Caroline M.;
Parmigiani, Raphael B.;
Andrade-Oliveira, Vinicius;
Volpini, Rildo A.;
Vinolo, Marco Aurélio R.;
Mariño, Eliana;
Robert, Remy;
Mackay, Charles R.;
Camara, Niels O. S.

Publication type:

Article

B-Cell Cross-Presentation of Autologous Antigen Precipitates Diabetes.

Published in:

Diabetes, 2012, v. 61, n. 11, p. 2893, doi. 10.2337/db12-0006

By:

Mariño, Eliana;
Tan, Bernice;
Binge, Lauren;
Mackay, Charles R.;
Grey, Shane T.

Publication type:

Article

Dual personality of memory T cells.

Published in:

Nature, 1999, v. 402, n. 6763, p. 3, doi. 10.1038/35005503

By:

Mackay, Charles R.

Publication type:

Article

Dual personality of memory T cells.

Published in:

Nature, 1999, v. 401, n. 6754, p. 659, doi. 10.1038/44309

By:

Mackay, Charles R.

Publication type:

Article

Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses.

Published in:

2007

By:

Jeffrey, Kate L.;
Camps, Montserrat;
Rommel, Christian;
Mackay, Charles R.

Publication type:

journal article

Maternal carriage of Prevotella during pregnancy associates with protection against food allergy in the offspring.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14552-1

By:

Vuillermin, Peter J.;
O'Hely, Martin;
Collier, Fiona;
Allen, Katrina J.;
Tang, Mimi L. K.;
Harrison, Leonard C.;
Carlin, John B.;
Saffery, Richard;
Ranganathan, Sarath;
Sly, Peter D.;
Gray, Lawrence;
Molloy, John;
Pezic, Angela;
Conlon, Michael;
Topping, David;
Nelson, Karen;
Mackay, Charles R.;
Macia, Laurence;
Koplin, Jennifer;
Dawson, Samantha L.

Publication type:

Article

Real-time interactive two-photon photoconversion of recirculating lymphocytes for discontinuous cell tracking in live adult mice.

Published in:

Journal of Biophotonics, 2014, v. 7, n. 6, p. 425, doi. 10.1002/jbio.201200175

By:

Chtanova, Tatyana;
Hampton, Henry R.;
Waterhouse, Louise A.;
Wood, Katherine;
Tomura, Michio;
Miwa, Yoshihiro;
Mackay, Charles R.;
Brink, Robert;
Phan, Tri Giang

Publication type:

Article

Chlamydia muridarumLung Infection in Infants Alters Hematopoietic Cells to Promote Allergic Airway Disease in Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042588

By:

Starkey, Malcolm R.;
Kim, Richard Y.;
Beckett, Emma L.;
Schilter, Heidi C.;
Shim, Doris;
Essilfie, Ama-Tawiah;
Nguyen, Duc H.;
Beagley, Kenneth W.;
Mattes, Joerg;
Mackay, Charles R.;
Horvat, Jay C.;
Hansbro, Philip M.;
Idzko, Marco

Publication type:

Article

Mice Deficient in GEM GTPase Show Abnormal Glucose Homeostasis Due to Defects in Beta-Cell Calcium Handling.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039462

By:

Gunton, Jenny E.;
Sisavanh, Mary;
Stokes, Rebecca A.;
Satin, Jon;
Satin, Leslie S.;
Min Zhang;
Liu, Sue M.;
Weikang Cai;
Kim Cheng;
Cooney, Gregory J.;
Laybutt, D. Ross;
Trina So;
Molero, Juan- Carlos;
Grey, Shane T.;
Andres, Douglas A.;
Rolph, Michael S.;
Mackay, Charles R.

Publication type:

Article

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.

Published in:

Nature, 2009, v. 461, n. 7268, p. 1282, doi. 10.1038/nature08530

By:

Maslowski, Kendle M.;
Vieira, Angelica T.;
Ng, Aylwin;
Kranich, Jan;
Sierro, Frederic;
Di Yu;
Schilter, Heidi C.;
Rolph, Michael S.;
Mackay, Fabienne;
Artis, David;
Xavier, Ramnik J.;
Teixeira, Mauro M.;
Mackay, Charles R.

Publication type:

Article

Book notes.

Published in:

1997

By:

MacKay, Charles R.

Publication type:

Book Review

Monocyte chemotactic protein-1, -2, and -3 are distinctively expressed in portal tracts and granulomata in primary biliary cirrhosis: implications for pathogenesis.

Published in:

Journal of Pathology, 2001, v. 193, n. 1, p. 102, doi. 10.1002/1096-9896(2000)9999:9999<::AID-PATH725>3.0.CO;2-P

By:

Tsuneyama, Koichi;
Harada, Kenichi;
Yasoshima, Mitsue;
Hiramatsu, Katsushi;
Mackay, Charles R.;
Mackay, Ian R.;
Gershwin, M. Eric;
Nakanuma, Yasuni

Publication type:

Article