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Patient‐ and xenograft‐derived organoids recapitulate pediatric brain tumor features and patient treatments.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 12, p. 1, doi. 10.15252/emmm.202318199
By:
- Lago, Chiara;
- Federico, Aniello;
- Leva, Gloria;
- Mack, Norman L;
- Schwalm, Benjamin;
- Ballabio, Claudio;
- Gianesello, Matteo;
- Abballe, Luana;
- Giovannoni, Isabella;
- Reddel, Sofia;
- Rossi, Sabrina;
- Leone, Nicolas;
- Carai, Andrea;
- Mastronuzzi, Angela;
- Bisio, Alessandra;
- Soldano, Alessia;
- Quintarelli, Concetta;
- Locatelli, Franco;
- Kool, Marcel;
- Miele, Evelina
Publication type:
Article
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11884-5
By:
- Pajtler, Kristian W.;
- Wei, Yiju;
- Okonechnikov, Konstantin;
- Silva, Patricia B. G.;
- Vouri, Mikaella;
- Zhang, Lei;
- Brabetz, Sebastian;
- Sieber, Laura;
- Gulley, Melissa;
- Mauermann, Monika;
- Wedig, Tatjana;
- Mack, Norman;
- Imamura Kawasawa, Yuka;
- Sharma, Tanvi;
- Zuckermann, Marc;
- Andreiuolo, Felipe;
- Holland, Eric;
- Maass, Kendra;
- Körkel-Qu, Huiqin;
- Liu, Hai-Kun
Publication type:
Article
Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression.
Published in:
Cancers, 2023, v. 15, n. 2, p. 479, doi. 10.3390/cancers15020479
By:
- Arseni, Lavinia;
- Sharma, Rakesh;
- Mack, Norman;
- Nagalla, Deepthi;
- Ohl, Sibylle;
- Hielscher, Thomas;
- Singhal, Mahak;
- Pilz, Robert;
- Augustin, Hellmut;
- Sandhoff, Roger;
- Herold-Mende, Christel;
- Tews, Björn;
- Lichter, Peter;
- Seiffert, Martina
Publication type:
Article
Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.
Published in:
Neuro-Oncology, 2021, v. 23, n. 12, p. 2028, doi. 10.1093/neuonc/noab127
By:
- Simovic, Milena;
- Bolkestein, Michiel;
- Moustafa, Mahmoud;
- Wong, John K L;
- Körber, Verena;
- Benedetto, Sarah;
- Khalid, Umar;
- Schreiber, Hannah Sophia;
- Jugold, Manfred;
- Korshunov, Andrey;
- Hübschmann, Daniel;
- Mack, Norman;
- Brons, Stephan;
- Wei, Pei-Chi;
- Breckwoldt, Michael O;
- Heiland, Sabine;
- Bendszus, Martin;
- Debus, Jürgen;
- Höfer, Thomas;
- Zapatka, Marc
Publication type:
Article
THER-02. TARGETING DNA DAMAGE REPAIR IN MYC-DRIVEN PEDIATRIC BRAIN TUMORS.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii114, doi. 10.1093/neuonc/noz036.209
By:
- Krausert, Sonja;
- Lambo, Sander;
- Brabetz, Sebastian;
- Mack, Norman;
- Schwalm, Benjamin;
- Pfister, Stefan;
- Kool, Marcel
Publication type:
Article
Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients.
Published in:
Neuro-Oncology, 2017, v. 19, n. 12, p. 1607, doi. 10.1093/neuonc/nox093
By:
- Schmidt, Christin;
- Schubert, Nil A.;
- Brabetz, Sebastian;
- Mack, Norman;
- Schwalm, Benjamin;
- Chan, Jennifer A.;
- Selt, Florian;
- Herold-Mende, Christel;
- Witt, Olaf;
- Milde, Till;
- Pfister, Stefan M.;
- Korshunov, Andrey;
- Kool, Marcel
Publication type:
Article
Perceived stress factors of adult caregivers related to institutionalization of a relative with Alzheimer's disease.
Published in:
American Journal of Alzheimer's Disease & Other Dementias, 1992, v. 7, n. 5, p. 24, doi. 10.1177/153331759200700506
By:
- Norman, Gwendolyn Mack;
- Calico, Patricia A.;
- Krebs, Judith Ann
Publication type:
Article
Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma.
Published in:
Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac026
By:
- Krausert, Sonja;
- Brabetz, Sebastian;
- Mack, Norman L.;
- Schmitt-Hoffner, Felix;
- Schwalm, Benjamin;
- Peterziel, Heike;
- Mangang, Aileen;
- Holland-Letz, Tim;
- Sieber, Laura;
- Korshunov, Andrey;
- Oehme, Ina;
- Jäger, Natalie;
- Witt, Olaf;
- Pfister, Stefan M.;
- Kool, Marcel
Publication type:
Article
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.
Published in:
British Journal of Cancer, 2024, v. 131, n. 4, p. 763, doi. 10.1038/s41416-024-02740-5
By:
- Seiboldt, Till;
- Zeiser, Constantia;
- Nguyen, Duy;
- Celikyürekli, Simay;
- Herter, Sonja;
- Najafi, Sara;
- Stroh-Dege, Alexandra;
- Meulenbroeks, Chris;
- Mack, Norman;
- Salem-Altintas, Rabia;
- Westermann, Frank;
- Schlesner, Matthias;
- Milde, Till;
- Kool, Marcel;
- Holland-Letz, Tim;
- Vogler, Meike;
- Peterziel, Heike;
- Witt, Olaf;
- Oehme, Ina
Publication type:
Article
RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas.
Published in:
Acta Neuropathologica, 2019, v. 138, n. 2, p. 275, doi. 10.1007/s00401-019-02021-z
By:
- Wirthschaft, Peter;
- Bode, Julia;
- Soni, Himanshu;
- Dietrich, Fabio;
- Krüwel, Thomas;
- Fischer, Bernd;
- Knobbe-Thomsen, Christiane B.;
- Rossetti, Giulia;
- Hentschel, Andreas;
- Mack, Norman;
- Schönig, Kai;
- Breckwoldt, Michael O.;
- Schmandke, André;
- Pusch, Stefan;
- Medenbach, Jan;
- Bendszus, Martin;
- Schwab, Martin E.;
- von Deimling, Andreas;
- Kool, Marcel;
- Herold-Mende, Christel
Publication type:
Article

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