Works matching AU Macheroux, Peter

Results: 78

Mechanisms of cell death induction by L-amino acid oxidase, a major component of ophidian venom.

Published in:

Apoptosis, 2006, v. 11, n. 8, p. 1439, doi. 10.1007/s10495-006-7959-9

By:

Ande, Sudharsana;
Kommoju, Phaneeswara;
Draxl, Sigrid;
Murkovic, Michael;
Macheroux, Peter;
Ghisla, Sandro;
Ferrando-May, Elisa

Publication type:

Article

Efficient Entropy‐Driven Inhibition of Dipeptidyl Peptidase III by Hydroxyethylene Transition‐State Peptidomimetics.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 56, p. 14108, doi. 10.1002/chem.202102204

By:

Ivkovic, Jakov;
Jha, Shalinee;
Lembacher‐Fadum, Christian;
Puschnig, Johannes;
Kumar, Prashant;
Reithofer, Viktoria;
Gruber, Karl;
Macheroux, Peter;
Breinbauer, Rolf

Publication type:

Article

Enantioselektive oxidative aerobe Desalkylierung von N-Ethylbenzyl-isochinolinen mithilfe des Berberin-Brücken-Enzyms.

Published in:

Angewandte Chemie, 2015, v. 127, n. 50, p. 15265, doi. 10.1002/ange.201507970

By:

Gandomkar, Somayyeh;
Fischereder, Eva-Maria;
Schrittwieser, Joerg H.;
Wallner, Silvia;
Habibi, Zohreh;
Macheroux, Peter;
Kroutil, Wolfgang

Publication type:

Article

Deracemisierung durch simultane bio-oxidative Racematspaltung und Stereoinversion.

Published in:

Angewandte Chemie, 2014, v. 126, n. 14, p. 3805, doi. 10.1002/ange.201400027

By:

Schrittwieser, Joerg H.;
Groenendaal, Bas;
Resch, Verena;
Ghislieri, Diego;
Wallner, Silvia;
Fischereder, Eva ‐ Maria;
Fuchs, Elisabeth;
Grischek, Barbara;
Sattler, Johann H.;
Macheroux, Peter;
Turner, Nicholas J.;
Kroutil, Wolfgang

Publication type:

Article

One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases.

Published in:

Angewandte Chemie, 2013, v. 125, n. 11, p. 3359, doi. 10.1002/ange.201209946

By:

Schober, Markus;
Toesch, Michael;
Knaus, Tanja;
Strohmeier, Gernot A.;
van Loo, Bert;
Fuchs, Michael;
Hollfelder, Florian;
Macheroux, Peter;
Faber, Kurt

Publication type:

Article

Aktivitätsbasierte Sondenmoleküle zur Untersuchung der Aktivität Flavin-abhängiger Oxidasen und zum Zielprotein-Profiling von Monoaminooxidase-Inhibitoren.

Published in:

Angewandte Chemie, 2012, v. 124, n. 28, p. 7142, doi. 10.1002/ange.201201955

By:

Krysiak, Joanna M.;
Kreuzer, Johannes;
Macheroux, Peter;
Hermetter, Albin;
Sieber, Stephan A.;
Breinbauer, Rolf

Publication type:

Article

Biokatalytische enantioselektive oxidative C-C-Kupplung durch C-H-Aktivierung mit molekularem Sauerstoff.

Published in:

Angewandte Chemie, 2011, v. 123, n. 5, p. 1100, doi. 10.1002/ange.201006268

By:

Schrittwieser, Joerg H.;
Resch, Verena;
Sattler, Johann H.;
Lienhart, Wolf-Dieter;
Durchschein, Katharina;
Winkler, Andreas;
Gruber, Karl;
Macheroux, Peter;
Kroutil, Wolfgang

Publication type:

Article

Titelbild: Biokatalytische enantioselektive oxidative C-C-Kupplung durch C-H-Aktivierung mit molekularem Sauerstoff (Angew. Chem. 5/2011).

Published in:

Angewandte Chemie, 2011, v. 123, n. 5, p. 999, doi. 10.1002/ange.201007479

By:

Schrittwieser, Joerg H.;
Resch, Verena;
Sattler, Johann H.;
Lienhart, Wolf-Dieter;
Durchschein, Katharina;
Winkler, Andreas;
Gruber, Karl;
Macheroux, Peter;
Kroutil, Wolfgang

Publication type:

Article

Simple, fast and inexpensive quantification of glycolate in the urine of patients with primary hyperoxaluria type 1.

Published in:

Urolithiasis, 2023, v. 51, n. 1, p. 1, doi. 10.1007/s00240-023-01426-6

By:

Boehm, Thomas;
Martin-Higueras, Cristina;
Friesser, Eva;
Zitta, Clara;
Wallner, Silvia;
Walli, Adam;
Kovacevic, Katarina;
Hubmann, Holger;
Klavins, Kristaps;
Macheroux, Peter;
Hoppe, Bernd;
Jilma, Bernd

Publication type:

Article

Nicotinamide-Dependent Ene Reductases as Alternative Biocatalysts for the Reduction of Activated Alkenes.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 26, p. 4963, doi. 10.1002/ejoc.201200776

By:

Durchschein, Katharina;
Wallner, Silvia;
Macheroux, Peter;
Schwab, Wilfried;
Winkler, Thorsten;
Kreis, Wolfgang;
Faber, Kurt

Publication type:

Article

Asymmetric Bioreduction of Activated Alkenes Using Cloned 12-Oxophytodienoate Reductase Isoenzymes OPR-1 and OPR-3 from Lycopersicon esculentum (Tomato): A Striking Change of Stereoselectivity.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 21, p. 3934, doi. 10.1002/anie.200605168

By:

Hall, Mélanie;
Stueckler, Clemens;
Kroutil, Wolfgang;
Macheroux, Peter;
Faber, Kurt

Publication type:

Article

Yeast Ortholog of Peptidase Family M49: the Role of Invariant Glu461 and Tyr327.

Published in:

Croatica Chemica Acta, 2012, v. 85, n. 4, p. 535, doi. 10.5562/cca2107

By:

Jajčanin-Jozić, Nina;
Macheroux, Peter;
Abramić, Marija

Publication type:

Article

Biocatalytic Enantioselective Oxidation of Sec‐Allylic Alcohols with Flavin‐Dependent Oxidases.

Published in:

Advanced Synthesis & Catalysis, 2019, v. 361, n. 22, p. 5264, doi. 10.1002/adsc.201900921

By:

Gandomkar, Somayyeh;
Jost, Etta;
Loidolt, Doris;
Swoboda, Alexander;
Pickl, Mathias;
Elaily, Wael;
Daniel, Bastian;
Fraaije, Marco W.;
Macheroux, Peter;
Kroutil, Wolfgang

Publication type:

Article

Inverting the Regioselectivity of the Berberine Bridge Enzyme by Employing Customized Fluorine-Containing Substrates.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 41, p. 13173, doi. 10.1002/chem.201201895

By:

Resch, Verena;
Lechner, Horst;
Schrittwieser, Joerg H.;
Wallner, Silvia;
Gruber, Karl;
Macheroux, Peter;
Kroutil, Wolfgang

Publication type:

Article

Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway.

Published in:

Molecular Microbiology, 2007, v. 65, n. 5, p. 1249, doi. 10.1111/j.1365-2958.2007.05861.x

By:

Ehammer, Heidemarie;
Rauch, Gernot;
Prem, Anna;
Kappes, Barbara;
Macheroux, Peter

Publication type:

Article

Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 15, p. 4015, doi. 10.1093/hmg/ddu115

By:

Bernkopf, Marie;
Webersinke, Gerald;
Tongsook, Chanakan;
Koyani, Chintan N.;
Rafiq, Muhammad A.;
Ayaz, Muhammad;
Müller, Doris;
Enzinger, Christian;
Aslam, Muhammad;
Naeem, Farooq;
Schmidt, Kurt;
Gruber, Karl;
Speicher, Michael R.;
Malle, Ernst;
Macheroux, Peter;
Ayub, Muhammad;
Vincent, John B.;
Windpassinger, Christian;
Duba, Hans-Christoph

Publication type:

Article

Novel Methods for the Quantification of Dipeptidyl Peptidase 3 (DPP3) Concentration and Activity in Human Blood Samples.

Published in:

Journal of Applied Laboratory Medicine, 2019, p. 943, doi. 10.1373/jalm.2018.027995

By:

Rehfeld, Linda;
Funk, Eugenia;
Jha, Shalinee;
Macheroux, Peter;
Melander, Olle;
Bergmann, Andreas

Publication type:

Article

Investigation of the inhibitory properties of azo-dyes on chorismate synthase from Paracoccidioides brasiliensis.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2427175

By:

Fuchs, Katharina;
Totaro, Massimo G.;
Toplak, Marina;
Bijelic, Aleksandar;
Macheroux, Peter

Publication type:

Article

Crystal structure of dipeptidyl peptidase III from the human gut symbiont Bacteroides thetaiotaomicron.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187295

By:

Sabljić, Igor;
Meštrović, Nevenka;
Vukelić, Bojana;
Macheroux, Peter;
Gruber, Karl;
Luić, Marija;
Abramić, Marija

Publication type:

Article

Structure of human phospholipase D3, a single‐strand exonuclease associated with Alzheimer's disease.

Published in:

FEBS Journal, 2024, v. 291, n. 24, p. 5394, doi. 10.1111/febs.17319

By:

Bijelic, Aleksandar;
Macheroux, Peter

Publication type:

Article

Loop 6 and the β‐hairpin flap are structural hotspots that determine cofactor specificity in the FMN‐dependent family of ene‐reductases.

Published in:

FEBS Journal, 2024, v. 291, n. 7, p. 1560, doi. 10.1111/febs.17055

By:

Kerschbaumer, Bianca;
Totaro, Massimo G.;
Friess, Michael;
Breinbauer, Rolf;
Bijelic, Aleksandar;
Macheroux, Peter

Publication type:

Article

In conversation with Peter Macheroux.

Published in:

FEBS Journal, 2023, v. 290, n. 9, p. 2208, doi. 10.1111/febs.16646

By:

Skourti, Eleni;
Macheroux, Peter

Publication type:

Article

The emerging role of dipeptidyl peptidase 3 in pathophysiology.

Published in:

FEBS Journal, 2023, v. 290, n. 9, p. 2246, doi. 10.1111/febs.16429

By:

Malovan, Grazia;
Hierzberger, Bettina;
Suraci, Samuele;
Schaefer, Maximilian;
Santos, Karine;
Jha, Shalinee;
Macheroux, Peter

Publication type:

Article

Closing the gap: yeast electron‐transferring flavoprotein links the oxidation of d‐lactate and d‐α‐hydroxyglutarate to energy production via the respiratory chain.

Published in:

FEBS Journal, 2019, v. 286, n. 18, p. 3611, doi. 10.1111/febs.14924

By:

Toplak, Marina;
Brunner, Julia;
Tabib, Chaitanya R.;
Macheroux, Peter

Publication type:

Article

The single berberine bridge enzyme homolog of Physcomitrella patens is a cellobiose oxidase.

Published in:

FEBS Journal, 2018, v. 285, n. 10, p. 1923, doi. 10.1111/febs.14458

By:

Toplak, Marina;
Wiedemann, Gertrud;
Ulićević, Jelena;
Daniel, Bastian;
Hoernstein, Sebastian N. W.;
Kothe, Jennifer;
Niederhauser, Johannes;
Reski, Ralf;
Winkler, Andreas;
Macheroux, Peter

Publication type:

Article

Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 ( NQO1).

Published in:

FEBS Journal, 2017, v. 284, n. 8, p. 1233, doi. 10.1111/febs.14051

By:

Lienhart, Wolf‐Dieter;
Strandback, Emilia;
Gudipati, Venugopal;
Koch, Karin;
Binter, Alexandra;
Uhl, Michael K.;
Rantasa, David M.;
Bourgeois, Benjamin;
Madl, Tobias;
Zangger, Klaus;
Gruber, Karl;
Macheroux, Peter

Publication type:

Article

Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant.

Published in:

FEBS Journal, 2016, v. 283, n. 19, p. 3587, doi. 10.1111/febs.13828

By:

Augustin, Peter;
Hromic, Altijana;
Pavkov‐Keller, Tea;
Gruber, Karl;
Macheroux, Peter

Publication type:

Article

3′-Enolpyruvyl-UMP, a Novel and Unexpected Metabolite in Nikkomycin Biosynthesis.

Published in:

ChemBioChem, 2005, v. 6, n. 11, p. 1974, doi. 10.1002/cbic.200500208

By:

Cristian Ginj;
Heinz Rüegger;
Nikolaus Amrhein;
Peter Macheroux

Publication type:

Article

Quinone reductase acts as a redox switch of the 20S yeast proteasome.

Published in:

EMBO Reports, 2009, v. 10, n. 1, p. 65, doi. 10.1038/embor.2008.218

By:

Sollner, Sonja;
Schober, Markus;
Wagner, Andrea;
Prem, Anna;
Lorkova, Lucie;
Palfey, Bruce A;
Groll, Michael;
Macheroux, Peter

Publication type:

Article

Evidence for the generation of myristylated FMN by bacterial luciferase.

Published in:

Molecular Microbiology, 2017, v. 104, n. 6, p. 1027, doi. 10.1111/mmi.13676

By:

Tabib, Chaitanya R.;
Brodl, Eveline;
Macheroux, Peter

Publication type:

Article

Understanding the riddle of amine oxidase flavoenzyme reactivity on the stereoisomers of N‐methyl‐dopa and N‐methyl‐tyrosine.

Published in:

Journal of Molecular Recognition, 2024, v. 37, n. 2, p. 1, doi. 10.1002/jmr.3068

By:

Gracia Carmona, Oriol;
Lahham, Majd;
Poliak, Peter;
Goj, Dominic;
Frießer, Eva;
Wallner, Silvia;
Macheroux, Peter;
Oostenbrink, Chris

Publication type:

Article

The structure of L-amino acid oxidase reveals the substrate trajectory into an enantiomerically conserved active site.

Published in:

EMBO Journal, 2000, v. 19, n. 16, p. 4204, doi. 10.1093/emboj/19.16.4204

By:

Pawelek, Peter D.;
Cheah, Jaime;
Coulombe, Rene;
Macheroux, Peter;
Ghisla, Sandro;
Vrielink, Alice

Publication type:

Article

Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-69160-6

By:

Kerschbaumer, Bianca;
Macheroux, Peter;
Bijelic, Aleksandar

Publication type:

Article

Subcellular localization and characterization of chorismate synthase in the apicomplexan....

Published in:

Molecular Microbiology, 2001, v. 40, n. 1, p. 65, doi. 10.1046/j.1365-2958.2001.02366.x

By:

Fitzpatrick, Teresa;
Ricken, Sigrid;
Lanzer, Michael;
Amrhen, Nikolaus;
Macheroux, Peter;
Kappes, Barbara

Publication type:

Article

A small molecule chaperone rescues the stability and activity of a cancer‐associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro.

Published in:

FEBS Letters, 2020, v. 594, n. 3, p. 424, doi. 10.1002/1873-3468.13636

By:

Strandback, Emilia;
Lienhart, Wolf‐Dieter;
Hromic‐Jahjefendic, Altijana;
Bourgeois, Benjamin;
Högler, Anja;
Waltenstorfer, Daniel;
Winkler, Andreas;
Zangger, Klaus;
Madl, Tobias;
Gruber, Karl;
Macheroux, Peter

Publication type:

Article

X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases

Published in:

FEBS Letters, 2009, v. 583, n. 13, p. 2179, doi. 10.1016/j.febslet.2009.06.009

By:

Neuwirth, Martina;
Strohmeier, Marco;
Windeisen, Volker;
Wallner, Silvia;
Deller, Sigrid;
Rippe, Karsten;
Sinning, Irmgard;
Macheroux, Peter;
Tews, Ivo

Publication type:

Article

Induction of apoptosis in yeast by L-amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma.

Published in:

Yeast, 2008, v. 25, n. 5, p. 349, doi. 10.1002/yea.1592

By:

Ande, Sudharsana Rao;
Fussi, Heike;
Knauer, Heide;
Murkovic, Michael;
Ghisla, Sandro;
Fröhlich, Kai-Uwe;
Macheroux, Peter

Publication type:

Article

Asymmetrische reduktive Carbocyclisierung durch modifizierte En‐Reduktasen.

Published in:

Angewandte Chemie, 2018, v. 130, n. 24, p. 7360, doi. 10.1002/ange.201802962

By:

Heckenbichler, Kathrin;
Schweiger, Anna;
Brandner, Lea Alexandra;
Binter, Alexandra;
Toplak, Marina;
Macheroux, Peter;
Gruber, Karl;
Breinbauer, Rolf

Publication type:

Article

Regioselektive para-Carboxylierung von Catecholen mit einer Prenylflavin-abhängigen Decarboxylase.

Published in:

Angewandte Chemie, 2017, v. 129, n. 44, p. 14081, doi. 10.1002/ange.201708091

By:

Payer, Stefan E.;
Marshall, Stephen A.;
Bärland, Natalie;
Sheng, Xiang;
Reiter, Tamara;
Dordic, Andela;
Steinkellner, Georg;
Wuensch, Christiane;
Kaltwasser, Susann;
Fisher, Karl;
Rigby, Stephen E. J.;
Macheroux, Peter;
Vonck, Janet;
Gruber, Karl;
Faber, Kurt;
Himo, Fahmi;
Leys, David;
Pavkov‐Keller, Tea;
Glueck, Silvia M.

Publication type:

Article

Heterologous expression of two FAD-dependent oxidases with ( S)-tetrahydroprotoberberine oxidase activity from Arge mone mexicana and Berberis wilsoniae in insect cells.

Published in:

Planta: An International Journal of Plant Biology, 2011, v. 233, n. 6, p. 1185, doi. 10.1007/s00425-011-1357-4

By:

Gesell, Andreas;
Díaz Chávez, Maria;
Kramell, Robert;
Piotrowski, Markus;
Macheroux, Peter;
Kutchan, Toni

Publication type:

Article

Characterization and cDNA-microarray expression analysis of 12-oxophytodienoate reductases reveals differential roles for octadecanoid biosynthesis in the local versus the systemic wound response.

Published in:

Plant Journal, 2002, v. 32, n. 4, p. 585, doi. 10.1046/j.1365-313X.2002.01449.x

By:

Strassner, Jochen;
Schaller, Florian;
Frick, Ursula B.;
Howe, Gregg A.;
Weiler, Elmar W.;
Amrhein, Nikolaus;
Macheroux, Peter;
Schaller, Andreas

Publication type:

Article

Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations.

Published in:

Nature Communications, 2014, v. 5, n. 6, p. 4150, doi. 10.1038/ncomms5150

By:

Steinkellner, Georg;
Gruber, Christian C.;
Pavkov-Keller, Tea;
Binter, Alexandra;
Steiner, Kerstin;
Winkler, Christoph;
Łyskowski, Andrzej;
Schwamberger, Orsolya;
Oberer, Monika;
Schwab, Helmut;
Faber, Kurt;
Macheroux, Peter;
Gruber, Karl

Publication type:

Article

Structure of a Berberine Bridge Enzyme-Like Enzyme with an Active Site Specific to the Plant Family Brassicaceae.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0156892

By:

Daniel, Bastian;
Wallner, Silvia;
Steiner, Barbara;
Oberdorfer, Gustav;
Kumar, Prashant;
van der Graaff, Eric;
Roitsch, Thomas;
Sensen, Christoph W.;
Gruber, Karl;
Macheroux, Peter

Publication type:

Article

A concerted mechanism for berberine bridge enzyme.

Published in:

Nature Chemical Biology, 2008, v. 4, n. 12, p. 739, doi. 10.1038/nchembio.123

By:

Winkler, Andreas;
Łyskowski, Andrzej;
Riedl, Sabrina;
Puhl, Martin;
Kutchan, Toni M.;
Macheroux, Peter;
Gruber, Karl

Publication type:

Article

Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino- d-riboflavin to the antibiotic roseoflavin.

Published in:

FEBS Journal, 2016, v. 283, n. 8, p. 1531, doi. 10.1111/febs.13690

By:

Tongsook, Chanakan;
Uhl, Michael K.;
Jankowitsch, Frank;
Mack, Matthias;
Gruber, Karl;
Macheroux, Peter

Publication type:

Article

Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction.

Published in:

FEBS Journal, 2015, v. 282, n. 16, p. 3060, doi. 10.1111/febs.13212

By:

Zafred, Domen;
Steiner, Barbara;
Teufelberger, Andrea R.;
Hromic, Altijana;
Karplus, P. Andrew;
Schofield, Christopher J.;
Wallner, Silvia;
Macheroux, Peter

Publication type:

Article

Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase1.

Published in:

FEBS Journal, 2014, v. 281, n. 20, p. 4691, doi. 10.1111/febs.12975

By:

Lienhart, Wolf ‐ Dieter;
Gudipati, Venugopal;
Uhl, Michael K.;
Binter, Alexandra;
Pulido, Sergio A.;
Saf, Robert;
Zangger, Klaus;
Gruber, Karl;
Macheroux, Peter

Publication type:

Article

Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates.

Published in:

FEBS Journal, 2012, v. 279, n. 23, p. 4374, doi. 10.1111/febs.12027

By:

Knaus, Tanja;
Schober, Markus;
Kepplinger, Bernhard;
Faccinelli, Martin;
Pitzer, Julia;
Faber, Kurt;
Macheroux, Peter;
Wagner, Ulrike

Publication type:

Article

Characterization of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis.

Published in:

FEBS Journal, 2011, v. 278, n. 21, p. 4122, doi. 10.1111/j.1742-4658.2011.08319.x

By:

Binter, Alexandra;
Oberdorfer, Gustav;
Hofzumahaus, Sebastian;
Nerstheimer, Stefanie;
Altenbacher, Georg;
Gruber, Karl;
Macheroux, Peter

Publication type:

Article

Flavogenomics - a genomic and structural view of flavin-dependent proteins.

Published in:

FEBS Journal, 2011, v. 278, n. 15, p. 2625, doi. 10.1111/j.1742-4658.2011.08202.x

By:

Macheroux, Peter;
Kappes, Barbara;
Ealick, Steven E.

Publication type:

Article