Works by MacGregor, Paula

Results: 16

Mapping diversity in African trypanosomes using high resolution spatial proteomics.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40125-z

By:

Moloney, Nicola M.;
Barylyuk, Konstantin;
Tromer, Eelco;
Crook, Oliver M.;
Breckels, Lisa M.;
Lilley, Kathryn S.;
Waller, Ross F.;
MacGregor, Paula

Publication type:

Article

Tackling protozoan parasites of cattle in sub-Saharan Africa.

Published in:

PLoS Pathogens, 2021, v. 17, n. 10, p. 1, doi. 10.1371/journal.ppat.1009955

By:

MacGregor, Paula;
Nene, Vishvanath;
Nisbet, R. Ellen R.

Publication type:

Article

Trypanosomal immune evasion, chronicity and transmission: an elegant balancing act.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 6, p. 431, doi. 10.1038/nrmicro2779

By:

MacGregor, Paula;
Szö?r, Balazs;
Savill, Nicholas J.;
Matthews, Keith R.

Publication type:

Article

How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?

Published in:

PLoS Pathogens, 2015, v. 11, n. 12, p. 1, doi. 10.1371/journal.ppat.1005259

By:

Schwede, Angela;
Macleod, Olivia J. S.;
MacGregor, Paula;
Carrington, Mark

Publication type:

Article

Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.

Published in:

PLoS Pathogens, 2018, v. 14, n. 7, p. 1, doi. 10.1371/journal.ppat.1007195

By:

Dewar, Caroline E.;
MacGregor, Paula;
Cooper, Sinclair;
Gould, Matthew K.;
Matthews, Keith R.;
Savill, Nicholas J.;
Schnaufer, Achim

Publication type:

Article

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

Published in:

Nature, 2014, v. 505, n. 7485, p. 681, doi. 10.1038/nature12864

By:

Mony, Binny M.;
MacGregor, Paula;
Ivens, Alasdair;
Rojas, Federico;
Cowton, Andrew;
Young, Julie;
Horn, David;
Matthews, Keith

Publication type:

Article

Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.

Published in:

Frontiers in Cellular & Infection Microbiology, 2013, v. 3, p. 1, doi. 10.3389/fcimb.2013.00078

By:

Rico, Eva;
Rojas, Federico;
Mony, Binny M.;
Szoor, Balazs;
MacGregor, Paula;
Matthews, Keith R.

Publication type:

Article

Identification of the regulatory elements controlling the transmission stage-specific gene expression of PAD1 in Trypanosoma brucei.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 16, p. 7705, doi. 10.1093/nar/gks533

By:

MacGregor, Paula;
Matthews, Keith R.

Publication type:

Article

Targeting Cattle-Borne Zoonoses and Cattle Pathogens Using a Novel Trypanosomatid-Based Delivery System.

Published in:

PLoS Pathogens, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.ppat.1002340

By:

Mott, G. Adam;
Wilson, Raymond;
Fernando, Anuruddika;
Robinson, Ailie;
MacGregor, Paula;
Kennedy, David;
Schaap, Dick;
Matthews, Jacqueline B.;
Matthews, Keith R.

Publication type:

Article

New discoveries in the transmission biology of sleeping sickness parasites: applying the basics.

Published in:

Journal of Molecular Medicine, 2010, v. 88, n. 9, p. 865, doi. 10.1007/s00109-010-0637-y

By:

MacGregor, Paula;
Matthews, Keith R.

Publication type:

Article

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15125-y

By:

Macleod, Olivia J. S.;
Bart, Jean-Mathieu;
MacGregor, Paula;
Peacock, Lori;
Savill, Nicholas J.;
Hester, Svenja;
Ravel, Sophie;
Sunter, Jack D.;
Trevor, Camilla;
Rust, Steven;
Vaughan, Tristan J.;
Minter, Ralph;
Mohammed, Shabaz;
Gibson, Wendy;
Taylor, Martin C.;
Higgins, Matthew K.;
Carrington, Mark

Publication type:

Article

Regulation of <i>Trypanosoma brucei</i> Total and Polysomal mRNA during Development within Its Mammalian Host.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067069

By:

Capewell, Paul;
Monk, Stephanie;
Ivens, Alasdair;
MacGregor, Paula;
Fenn, Katelyn;
Walrad, Pegine;
Bringaud, Frederic;
Smith, Terry K.;
Matthews, Keith R.

Publication type:

Article

Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.13044

By:

Lane-Serff, Harriet;
MacGregor, Paula;
Peacock, Lori;
Macleod, Olivia J. S.;
Kay, Christopher;
Gibson, Wendy;
Higgins, Matthew K.;
Carrington, Mark

Publication type:

Article

Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.

Published in:

PLoS Pathogens, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.ppat.1007145

By:

McDonald, Lindsay;
Cayla, Mathieu;
Ivens, Alasdair;
Mony, Binny;
MacGregor, Paula;
Silvester, Eleanor;
McWilliam, Kirsty;
Matthews, Keith R.

Publication type:

Article

A Receptor’s Tale: An Eon in the Life of a Trypanosome Receptor.

Published in:

PLoS Pathogens, 2017, v. 13, n. 1, p. 1, doi. 10.1371/journal.ppat.1006055

By:

Higgins, Matthew K.;
Lane-Serff, Harriet;
MacGregor, Paula;
Carrington, Mark

Publication type:

Article

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 5, p. 1, doi. 10.1371/journal.pntd.0007373

By:

MacGregor, Paula;
Gonzalez-Munoz, Andrea L.;
Jobe, Fatoumatta;
Taylor, Martin C.;
Rust, Steven;
Sandercock, Alan M.;
Macleod, Olivia J. S.;
Van Bocxlaer, Katrien;
Francisco, Amanda F.;
D’Hooge, Francois;
Tiberghien, Arnaud;
Barry, Conor S.;
Howard, Philip;
Higgins, Matthew K.;
Vaughan, Tristan J.;
Minter, Ralph;
Carrington, Mark

Publication type:

Article