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Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.89712
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- Publication type:
- Article
Interpretable deep learning reveals the role of an E-box motif in suppressing somatic hypermutation of AGCT motifs within human immunoglobulin variable regions.
- Published in:
- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1407470
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- Article
Modular cytosine base editing promotes epigenomic and genomic modifications.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 2, p. e8, doi. 10.1093/nar/gkad1118
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- Publication type:
- Article
Evolutionary potential of the monkeypox genome arising from interactions with human APOBEC3 enzymes.
- Published in:
- Virus Evolution, 2023, v. 9, n. 2, p. 1, doi. 10.1093/ve/vead047
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- Article
Beta human papillomavirus 8E6 promotes alternative end joining.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.81923
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- Publication type:
- Article
Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice.
- Published in:
- Nucleic Acids Research, 2022, v. 50, n. 14, p. 8093, doi. 10.1093/nar/gkac616
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- Publication type:
- Article
In Memory of Eavan Boland.
- Published in:
- ABEI Journal: The Brazilian Journal of Irish Studies, 2021, v. 23, n. 2, p. 230, doi. 10.37389/abei.v23i2.197796
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- Publication type:
- Article
A Bayesian model based computational analysis of the relationship between bisulfite accessible single-stranded DNA in chromatin and somatic hypermutation of immunoglobulin genes.
- Published in:
- PLoS Computational Biology, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pcbi.1009323
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- Publication type:
- Article
Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.640731
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- Publication type:
- Article
Characterization of DNA G-Quadruplex Structures in Human Immunoglobulin Heavy Variable (IGHV) Genes.
- Published in:
- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.671944
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- Publication type:
- Article
Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection.
- Published in:
- PLoS Pathogens, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.ppat.1009560
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- Publication type:
- Article
Correlations in Somatic Hypermutation Between Sites in IGHV Genes Can Be Explained by Interactions Between AID and/or Polη Hotspots.
- Published in:
- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.618409
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- Publication type:
- Article
STAT3 imparts BRCAness by impairing homologous recombination repair in Epstein-Barr virus-transformed B lymphocytes.
- Published in:
- PLoS Pathogens, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.ppat.1008849
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- Article
AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes.
- Published in:
- Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00788
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- Publication type:
- Article
A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks.
- Published in:
- BMC Evolutionary Biology, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12862-019-1472-6
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- Publication type:
- Article
Evolutionary effects of the AID/APOBEC family of mutagenic enzymes on human gamma-herpesviruses.
- Published in:
- Virus Evolution, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1093/ve/vey040
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- Publication type:
- Article
Correction to: The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure.
- Published in:
- 2018
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- Publication type:
- Correction Notice
The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure.
- Published in:
- BMC Bioinformatics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12859-018-2161-y
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- Publication type:
- Article
The preferred nucleotide contexts of the AID/APOBEC cytidine deaminases have differential effects when mutating retrotransposon and virus sequences compared to host genes.
- Published in:
- PLoS Computational Biology, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pcbi.1005471
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- Article
The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia.
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- PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0167602
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- Publication type:
- Article
Potential for evolution of complex defense strategies in a multi-scale model of virus-host coevolution.
- Published in:
- BMC Evolutionary Biology, 2016, v. 16, p. 1, doi. 10.1186/s12862-016-0804-z
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- Publication type:
- Article
Cancer as the Disintegration of Robustness.
- Published in:
- Archives of Pathology & Laboratory Medicine, 2015, v. 139, n. 11, p. 1362, doi. 10.5858/arpa.2014-0624-OA
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- Publication type:
- Article
Antagonistic Coevolution Drives Whack-a-Mole Sensitivity in Gene Regulatory Networks.
- Published in:
- PLoS Computational Biology, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pcbi.1004432
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- Publication type:
- Article
Regulatory Evolution and Voltage-Gated Ion Channel Expression in Squid Axon: Selection-Mutation Balance and Fitness Cliffs.
- Published in:
- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0120785
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- Publication type:
- Article
Epigenetics Decouples Mutational from Environmental Robustness. Did It Also Facilitate Multicellularity?
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- PLoS Computational Biology, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pcbi.1003450
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- Article
The Underlying Molecular and Network Level Mechanisms in the Evolution of Robustness in Gene Regulatory Networks.
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- PLoS Computational Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pcbi.1002865
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- Article
Differential regulation drives plasticity in sex determination gene networks.
- Published in:
- BMC Evolutionary Biology, 2010, v. 10, p. 388, doi. 10.1186/1471-2148-10-388
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- Article
Buffering Mechanisms in Aging: A Systems Approach Toward Uncovering the Genetic Component of Aging.
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- PLoS Computational Biology, 2007, v. 3, n. 8, p. 1648, doi. 10.1371/journal.pcbi.0030170
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- Article
The limits of subfunctionalization.
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- BMC Evolutionary Biology, 2007, v. 7, p. 213, doi. 10.1186/1471-2148-7-213
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- Publication type:
- Article
Using large-scale perturbations in gene network reconstruction.
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- BMC Bioinformatics, 2005, v. 6, p. 11, doi. 10.1186/1471-2105-6-11
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- Publication type:
- Article