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The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 20, doi. 10.3390/ijms22010020
By:
- Bartlett, Mitchell J.;
- Mabrouk, Omar S.;
- Szabò, Lajos;
- Flores, Andrew J.;
- Parent, Kate L.;
- Bidlack, Jean M.;
- Heien, Michael L.;
- Kennedy, Robert T.;
- Polt, Robin;
- Sherman, Scott J.;
- Falk, Torsten
Publication type:
Article
Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons.
Published in:
eLife, 2015, p. 1, doi. 10.7554/eLife.08352
By:
- Pappas, Samuel S.;
- Darr, Katherine;
- Holley, Sandra M.;
- Cepeda, Carlos;
- Mabrouk, Omar S.;
- Wong, Jenny-Marie T.;
- LeWitt, Tessa M.;
- Paudel, Reema;
- Houlden, Henry;
- Kennedy, Robert T.;
- Levine, Michael S.;
- Dauer, William T.
Publication type:
Article
Collection, storage, and electrophoretic analysis of nanoliter microdialysis samples collected from awake animals in vivo.
Published in:
Analytical & Bioanalytical Chemistry, 2011, v. 400, n. 7, p. 2013, doi. 10.1007/s00216-011-4956-9
By:
- Meng Wang;
- Hershey, Neil D.;
- Mabrouk, Omar S.;
- Kennedy, Robert T.
Publication type:
Article
Age-dependent dopamine transporter dysfunction and Serine129 phospho-α- synuclein overload in G2019S LRRK2 mice.
Published in:
Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0426-8
By:
- Longo, Francesco;
- Mercatelli, Daniela;
- Novello, Salvatore;
- Arcuri, Ludovico;
- Brugnoli, Alberto;
- Vincenzi, Fabrizio;
- Russo, Isabella;
- Berti, Giulia;
- Mabrouk, Omar S.;
- Kennedy, Robert T.;
- Shimshek, Derya R.;
- Varani, Katia;
- Bubacco, Luigi;
- Greggio, Elisa;
- Morari, Michele
Publication type:
Article
Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers.
Published in:
Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0492-y
By:
- Shijie Wang;
- Zhiyong Liu;
- Tao Ye;
- Mabrouk, Omar S.;
- Maltbie, Tyler;
- Aasly, Jan;
- West, Andrew B.
Publication type:
Article
The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson's Disease.
Published in:
Frontiers in Neuroscience, 2020, p. N.PAG, doi. 10.3389/fnins.2020.00865
By:
- Rideout, Hardy J.;
- Chartier-Harlin, Marie-Christine;
- Fell, Matthew J.;
- Hirst, Warren D.;
- Huntwork-Rodriguez, Sarah;
- Leyns, Cheryl E. G.;
- Mabrouk, Omar S.;
- Taymans, Jean-Marc
Publication type:
Article
Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients.
Published in:
Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00526
By:
- Mabrouk, Omar S.;
- Chen, Siwei;
- Edwards, Amanda L.;
- Yang, Minhua;
- Hirst, Warren D.;
- Graham, Danielle L.
Publication type:
Article
Evidence for the Preferential Involvement of 5-HT2A Serotonin Receptors in Stress- and Drug-Induced Dopamine Release in the Rat Medial Prefrontal Cortex.
Published in:
Neuropsychopharmacology, 2006, v. 31, n. 2, p. 265, doi. 10.1038/sj.npp.1300819
By:
- Pehek, Elizabeth A.;
- Nocjar, Christine;
- Roth, Bryan L.;
- Byrd, Tara A.;
- Mabrouk, Omar S.
Publication type:
Article
Distinctive immunoregulatory effects of adenosine on T cells of older humans.
Published in:
FASEB Journal, 2012, v. 26, n. 3, p. 1301, doi. 10.1096/fj.11-197046
By:
- Hesdorffer, Charles S.;
- Malchinkhuu, Enkhzol;
- Biragyn, Arya;
- Mabrouk, Omar S.;
- Kennedy, Robert T.;
- Madara, Karen;
- Taub, Dennis D.;
- Longo, Dan L.;
- Schwartz, Janice B.;
- Ferrucci, Luigi;
- Goetzl, Edward J.
Publication type:
Article
Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum.
Published in:
European Journal of Neuroscience, 2019, v. 50, n. 3, p. 2054, doi. 10.1111/ejn.13941
By:
- Minogianis, Ellie‐Anna;
- Shams, Waqqas M.;
- Mabrouk, Omar S.;
- Wong, Jenny‐Marie T.;
- Brake, Wayne G.;
- Kennedy, Robert T.;
- Souich, Patrick;
- Samaha, Anne‐Noël
Publication type:
Article
Amphetamine stimulates movement through thalamocortical glutamate release.
Published in:
Journal of Neurochemistry, 2014, v. 128, n. 1, p. 152, doi. 10.1111/jnc.12378
By:
- Mabrouk, Omar S.;
- Semaan, Daniel Z.;
- Mikelman, Sarah;
- Gnegy, Margaret E.;
- Kennedy, Robert T.
Publication type:
Article
Microdialysis and mass spectrometric monitoring of dopamine and enkephalins in the globus pallidus reveal reciprocal interactions that regulate movement.
Published in:
Journal of Neurochemistry, 2011, v. 118, n. 1, p. 24, doi. 10.1111/j.1471-4159.2011.07293.x
By:
- Mabrouk, Omar S.;
- Qiang Li;
- Peng Song;
- Kennedy, Robert T.
Publication type:
Article
Further evidence for an involvement of nociceptin/orphanin FQ in the pathophysiology of Parkinson's disease: a behavioral and neurochemical study in reserpinized mice.
Published in:
Journal of Neurochemistry, 2010, v. 115, n. 6, p. 1543, doi. 10.1111/j.1471-4159.2010.07061.x
By:
- Volta, Mattia;
- Mabrouk, Omar S.;
- Bido, Simone;
- Marti, Matteo;
- Morari, Michele
Publication type:
Article
LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease.
Published in:
Movement Disorders, 2023, v. 38, n. 3, p. 386, doi. 10.1002/mds.29297
By:
- Jennings, Danna;
- Huntwork‐Rodriguez, Sarah;
- Vissers, Maurits F.J.M.;
- Daryani, Vinay M.;
- Diaz, Dolores;
- Goo, Marisa S.;
- Chen, John J.;
- Maciuca, Romeo;
- Fraser, Kyle;
- Mabrouk, Omar S.;
- van de Wetering de Rooij, Jeroen;
- Heuberger, Jules A.A.C.;
- Groeneveld, Geert Jan;
- Borin, Marie T.;
- Cruz‐Herranz, Andrés;
- Graham, Danielle;
- Scearce‐Levie, Kimberly;
- De Vicente, Javier;
- Henry, Anastasia G.;
- Chin, Peter
Publication type:
Article
Glucocerebrosidase Activity Is Not Associated with Parkinson's Disease Risk or Severity.
Published in:
Movement Disorders, 2022, v. 37, n. 3, p. 651, doi. 10.1002/mds.28929
By:
- Omer, Nurit;
- Giladi, Nir;
- Gurevich, Tanya;
- Bar‐Shira, Anat;
- Gana‐Weisz, Mali;
- Glinka, Tal;
- Goldstein, Orly;
- Kestenbaum, Meir;
- Cedarbaum, Jesse M.;
- Mabrouk, Omar S.;
- Fraser, Kyle B.;
- Shirvan, Julia C.;
- Orr‐Urtreger, Avi;
- Mirelman, Anat;
- Thaler, Avner
Publication type:
Article
Glucocerebrosidase Activity is not Associated with Parkinson's Disease Risk or Severity.
Published in:
Movement Disorders, 2022, v. 37, n. 1, p. 190, doi. 10.1002/mds.28792
By:
- Omer, Nurit;
- Giladi, Nir;
- Gurevich, Tanya;
- Bar‐Shira, Anat;
- Gana‐Weisz, Mali;
- Glinka, Tal;
- Goldstein, Orly;
- Kestenbaum, Meir;
- Cedarbaum, Jesse M.;
- Mabrouk, Omar S.;
- Fraser, Kyle B.;
- Shirvan, Julia C.;
- Orr‐Urtreger, Avi;
- Mirelman, Anat;
- Thaler, Avner
Publication type:
Article
Rapid dopamine transmission within the nucleus accumbens: Dramatic difference between morphine and oxycodone delivery.
Published in:
European Journal of Neuroscience, 2014, v. 40, n. 7, p. 3041, doi. 10.1111/ejn.12709
By:
- Vander Weele, Caitlin M.;
- Porter‐Stransky, Kirsten A.;
- Mabrouk, Omar S.;
- Lovic, Vedran;
- Singer, Bryan F.;
- Kennedy, Robert T.;
- Aragona, Brandon J.
Publication type:
Article
Stimulation of delta opioid receptors located in substantia nigra reticulata but not globus pallidus or striatum restores motor activity in 6-hydroxydopamine lesioned rats: new insights into the role of delta receptors in parkinsonism.
Published in:
Journal of Neurochemistry, 2008, v. 107, n. 6, p. 1647, doi. 10.1111/j.1471-4159.2008.05727.x
By:
- Mabrouk, Omar S.;
- Volta, Mattia;
- Marti, Matteo;
- Morari, Michele
Publication type:
Article
Pre-existing differences and diet-induced alterations in striatal dopamine systems of obesity-prone rats.
Published in:
2016
By:
- Vollbrecht, Peter J.;
- Mabrouk, Omar S.;
- Nelson, Andrew D.;
- Kennedy, Robert T.;
- Ferrario, Carrie R.
Publication type:
journal article
Stimulation of δ Opioid Receptor and Blockade of Nociceptin/Orphanin FQ Receptor Synergistically Attenuate Parkinsonism.
Published in:
Journal of Neuroscience, 2014, v. 34, n. 39, p. 12953, doi. 10.1523/JNEUROSCI.4677-13.2014
By:
- Mabrouk, Omar S.;
- Viaro, Riccardo;
- Volta, Mattia;
- Ledonne, Ada;
- Mercuri, Nicola;
- Morari, Michele
Publication type:
Article

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