Works by MOXON, E. RICHARD

Results: 76

The tinkerer's evolving tool-box.

Published in:

Nature, 1997, v. 387, n. 6634, p. 659, doi. 10.1038/42607

By:

Moxon, E. Richard;
Thaler, David S.

Publication type:

Article

The Development of a Vaccine Against Meningococcus B Using Reverse Vaccinology.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00751

By:

Masignani, Vega;
Pizza, Mariagrazia;
Moxon, E. Richard

Publication type:

Article

High allelic diversity in the methyltransferase gene of a phase variable type III restriction-modification system has implications for the fitness of Haemophilus influenzae.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 14, p. 4046, doi. 10.1093/nar/gkl568

By:

Bayliss, Christopher D.;
Callaghan, Martin J.;
Moxon, E. Richard

Publication type:

Article

Destabilization of tetranucleotide repeats in Haemophilus influenzae mutants lacking RnaseHI or the Klenow domain of PolI.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 1, p. 400, doi. 10.1093/nar/gki180

By:

Bayliss, Christopher D.;
Sweetman, Wendy A.;
Moxon, E. Richard

Publication type:

Article

Immunological Memory: The Role of B Cells in Long-term Protection Against Invasive Bacterial Pathogens.

Published in:

JAMA: Journal of the American Medical Association, 2005, v. 294, n. 23, p. 3019, doi. 10.1001/jama.294.23.3019

By:

Kelly, Dominic F.;
Pollard, Andrew J.;
Moxon, E. Richard

Publication type:

Article

Immunogenicity and Safety of a Combination Pneumococcal-Meningococcal Vaccine in Infants: A Randomized Controlled Trial.

Published in:

JAMA: Journal of the American Medical Association, 2005, v. 293, n. 14, p. 1751, doi. 10.1001/jama.293.14.1751

By:

Buttery, Jim P.;
Riddell, Anna;
McVernon, Jodie;
Chantler, Tracey;
Lane, Laura;
Bowen-Morris, Jane;
Diggle, Linda;
Morris, Rhonwen;
Harnden, Anthony;
Lockhart, Steven;
Pollard, Andrew J.;
Cartwright, Keith;
Moxon, E. Richard

Publication type:

Article

Application of capillary electrophoresis- electrospray-mass spectrometry to the separation and characterization of isomeric lipopolysaccharides of Neisseria meningitidis.

Published in:

Electrophoresis, 2004, v. 25, n. 13, p. 2017, doi. 10.1002/elps.200305824

By:

Jianjun Li;
Andrew D. Cox;
Derek Hood;
E. Richard Moxon;
James C. Richards

Publication type:

Article

Diurnal Differences in Intracellular Replication Within Splenic Macrophages Correlates With the Outcome of Pneumococcal Infection.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.907461

By:

Hames, Ryan G.;
Jasiunaite, Zydrune;
Ercoli, Giuseppe;
Wanford, Joseph J.;
Carreno, David;
Straatman, Kornelis;
Martinez-Pomares, Luisa;
Yesilkaya, Hasan;
Glenn, Sarah;
Moxon, E. Richard;
Andrew, Peter W.;
Kyriacou, Charalambos P.;
Oggioni, Marco R.

Publication type:

Article

Identification of a gene (lpt-3 ) required for the addition of phosphoethanolamine to the lipopolysaccharide inner core of Neisseria meningitidis and its role in mediating susceptibility to bactericidal killing and opsonophagocytosis.

Published in:

Molecular Microbiology, 2002, v. 43, n. 4, p. 931, doi. 10.1046/j.1365-2958.2002.02754.x

By:

Mackinnon, Fiona G;
Cox, Andrew D;
Plested, Joyce S;
Tang, Christoph M;
Makepeace, Katherine;
Coull, Philip A;
Wright, J. Claire;
Chalmers, Ronald;
Hood, Derek W;
Richards, James C;
Moxon, E. Richard

Publication type:

Article

Identification of a lipopolysaccharide α-2,3-sialyltransferase from Haemophilus influenzae.

Published in:

Molecular Microbiology, 2001, v. 39, n. 2, p. 341, doi. 10.1046/j.1365-2958.2001.02204.x

By:

Hood, Derek W.;
Cox, Andrew D.;
Gilbert, Michel;
Makepeace, Katherine;
Walsh, Shannon;
Deadman, Mary E.;
Cody, Alison;
Martin, Adele;
Månsson, Martin;
Schweda, Elke K. H.;
Brisson, Jean-Robert;
Richards, James C.;
Moxon, E. Richard;
Wakarchuk, Warren W.

Publication type:

Article

Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58.

Published in:

Molecular Microbiology, 2000, v. 37, n. 1, p. 207, doi. 10.1046/j.1365-2958.2000.02000.x

By:

Saunders, Nigel J;
Jeffries, Alex C;
Peden, John F;
Hood, Derek W;
Tettelin, Herve;
Rappuoli, Rino;
Moxon, E. Richard

Publication type:

Article

High rates of phase variation in Campylobacter jejuni.

Published in:

Molecular Microbiology, 2000, v. 36, n. 6, p. 1504, doi. 10.1046/j.1365-2958.2000.01947.x

By:

Saunders, Nigel J.;
Jeffries, Alex C.;
Hood, Derek W.;
Moxon, E. Richard

Publication type:

Article

The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases.

Published in:

Molecular Microbiology, 2000, v. 35, n. 1, p. 211, doi. 10.1046/j.1365-2958.2000.01701.x

By:

De Bolle, Xavier;
Bayliss, Christopher D;
Field, Dawn;
van de Ven, Tamsin;
Saunders, Nigel J;
Hood, Derek W;
Moxon, E. Richard

Publication type:

Article

Sialic acid in the lipopolysaccharide of Haemophilus influenzae: strain distribution, influence on serum resistance and structural characterization.

Published in:

Molecular Microbiology, 1999, v. 33, n. 4, p. 679, doi. 10.1046/j.1365-2958.1999.01509.x

By:

Hood, Derek W;
Makepeace, Katherine;
Deadman, Mary E;
Rest, Richard F;
Thibault, Pierre;
Martin, Adele;
Richards, James C;
Moxon, E. Richard

Publication type:

Article

Identification of a novel gene involved in pilin glycosylation in Neisseria meningitidis.

Published in:

Molecular Microbiology, 1998, v. 29, n. 4, p. 975, doi. 10.1046/j.1365-2958.1998.00962.x

By:

Jennings, Michael P.;
Virji, Mumtaz;
Evans, Debbie;
Foster, Virginia;
Srikhanta, Yogitha N.;
Steeghs, Liana;
van der Ley, Peter;
Moxon, E. Richard

Publication type:

Article

Simple sequence repeats in the Helicobacter pylori genome.

Published in:

Molecular Microbiology, 1998, v. 27, n. 6, p. 1091, doi. 10.1046/j.1365-2958.1998.00768.x

By:

Saunders, Nigel J.;
Peden, John F.;
Hood, Derek W.;
Moxon, E. Richard

Publication type:

Article

Use of the complete genome sequence information of Haemophilus influenzae strain Rd to investigate lipopolysaccharide biosynthesis.

Published in:

Molecular Microbiology, 1996, v. 22, n. 5, p. 951, doi. 10.1046/j.1365-2958.1996.01545.x

By:

Hood, Derek W.;
Deadman, Mary E.;
Allen, Tina;
Masoud, Hussein;
Martin, Adele;
Brisson, Jean Robert;
Fleischmann, Robert;
Venter, J. Craig;
Richards, James C.;
Moxon, E. Richard

Publication type:

Article

Tandem repeats of the tetramer 5′ -CAAT-3′ present in lic2A are required for phase variation but not lipopolysaccharide biosynthesis in Haemophilus influenzae.

Published in:

Molecular Microbiology, 1996, v. 20, n. 1, p. 165, doi. 10.1111/j.1365-2958.1996.tb02498.x

By:

High, Nicola J.;
Jennings, Michael P.;
Moxon, E. Richard

Publication type:

Article

Identification of a locus involved in meningococcal lipopolysaccharide biosynthesis by deletion mutagenesis.

Published in:

Molecular Microbiology, 1996, v. 19, n. 5, p. 1117, doi. 10.1046/j.1365-2958.1996.464992.x

By:

Van der Ley, Peter;
Kramer, Marco;
Steeghs, Liana;
Kuipers, Betsy;
Andersen, Svein R.;
Jennings, Michael P.;
Moxon, E. Richard;
Poolman, Jan T.

Publication type:

Article

Ope- and pilus-dependent interactions of meningococci with human endothelial cells: molecular mechanisms and modulation by surface polysaccharides.

Published in:

Molecular Microbiology, 1995, v. 18, n. 4, p. 741, doi. 10.1111/j.1365-2958.1995.mmi_18040741.x

By:

Virji, Mumtaz;
Makepeace, Katherine;
Peak, Ian R. A.;
Ferguson, David J. P.;
Jennings, Michael P.;
Moxon, E. Richard

Publication type:

Article

Molecular analysis of a locus for the biosynthesis and phase-variable expression of the lacto-A/-neotetraose terminal lipopolysaccharide structure in Neisseria meningitidis.

Published in:

Molecular Microbiology, 1995, v. 18, n. 4, p. 729, doi. 10.1111/j.1365-2958.1995.mmi_18040729.x

By:

Jennings, Michael P.;
Hood, Derek W.;
Peak, Ian R. A.;
Virji, Mumtaz;
Moxon, E. Richard

Publication type:

Article

Meningococcal pilin: a glycoprotein substituted with digalactosyl 2,4-diacetamido-2,4,6-trideoxyhexose.

Published in:

Molecular Microbiology, 1995, v. 17, n. 6, p. 1201, doi. 10.1111/j.1365-2958.1995.mmi_17061201.x

By:

Stimson, Elaine;
Virji, Mumtaz;
Makepeace, Katherine;
Dell, Anne;
Morris, Howard R.;
Payne, Gail;
Saunders, Jon R.;
Jennings, Michael P.;
Barker, Stephanie;
Panico, Maria;
Blench, Ian;
Moxon, E. Richard

Publication type:

Article

Functional implications of the expression of PilC proteins in meningococci.

Published in:

Molecular Microbiology, 1995, v. 16, n. 6, p. 1087, doi. 10.1111/j.1365-2958.1995.tb02334.x

By:

Virji, Mumtaz;
Makepeace, Katherine;
Peak, Ian;
Payne, Gail;
Saunders, Jon R.;
Ferguson, David J. P.;
Moxon, E. Richard

Publication type:

Article

Region II of the Haemophilus influenzae Type b capsulation locus is involved in serotype--specific polysaccharide synthesis.

Published in:

Molecular Microbiology, 1995, v. 15, n. 1, p. 107, doi. 10.1111/j.1365-2958.1995.tb02225.x

By:

Van Eldere, Johan;
Brophy, Lisa;
Loynds, Barbara;
Celis, Patrick;
Hancock, Lan;
Carman, Stephen;
Kroll, J. Simon;
Moxon, E. Richard

Publication type:

Article

Distinct mechanisms of interactions of Opc-expressing meningococci at apical and basolateral surfaces of human endothelial cells; the role of integrins in apical interactions.

Published in:

Molecular Microbiology, 1994, v. 14, n. 1, p. 173, doi. 10.1111/j.1365-2958.1994.tb01277.x

By:

Virji, Mumtaz;
Makepeace, Katherine;
Moxon, E. Richard

Publication type:

Article

Variable expression of the Opc outer membrane protein in <em>Neisseria meningitidis</em> is caused by size variation of a promoter containing poly-cytidine.

Published in:

Molecular Microbiology, 1994, v. 13, n. 2, p. 207, doi. 10.1111/j.1365-2958.1994.tb00416.x

By:

Sarkari, Jasmine;
Pandit, Niketan;
Moxon, E. Richard;
Achtman, Mark

Publication type:

Article

Meningococcal Opa and Opc proteins: their role in colonization and invasion of human epithelial and endothelial cells.

Published in:

Molecular Microbiology, 1993, v. 10, n. 3, p. 499, doi. 10.1111/j.1365-2958.1993.tb00922.x

By:

Virji, Mumtaz;
Makepeace, Katherine;
Ferguson, David J. P.;
Achtman, Mark;
Moxon, E. Richard

Publication type:

Article

Cloning and molecular analysis of the gaIE gene of Neisseria meningitidis and its role in lipopolysaccharide biosynthesis.

Published in:

Molecular Microbiology, 1993, v. 10, n. 2, p. 361, doi. 10.1111/j.1365-2958.1993.tb01962.x

By:

Jennings, Michael P.;
Van der Ley, Peter;
Wilks, Kathy E.;
Maskell, Duncan J.;
Poolman, Jan T.;
Moxon, E. Richard

Publication type:

Article

The role of a repetitive DNA motif (5'-CAAT-3') in the variable expression of the Haemophilus influenzae lipopolysaccharide epitope αGal(1-4)βGal.

Published in:

Molecular Microbiology, 1993, v. 9, n. 6, p. 1275, doi. 10.1111/j.1365-2958.1993.tb01257.x

By:

High, Nicola J.;
Deadman, Mary E.;
Moxon, E. Richard

Publication type:

Article

Expression of the Opc protein correlates with invasion of epithelial and endothelial cells by <em>Neisseria meningitidis</em>.

Published in:

Molecular Microbiology, 1992, v. 6, n. 19, p. 2785, doi. 10.1111/j.1365-2958.1992.tb01458.x

By:

Virji, Mumtaz;
Makepeace, Katherine;
Ferguson, David J. P.;
Achtman, Mark;
Sarkari, Jasmine;
Moxon, E. Richard

Publication type:

Article

Variations in the expression of pili: the effect on adherence of Neisseria meningitidisto human epithelial and endothelial cells.

Published in:

Molecular Microbiology, 1992, v. 6, n. 10, p. 1271, doi. 10.1111/j.1365-2958.1992.tb00848.x

By:

Virji, Mumtaz;
Alexandrescu, Carol;
Ferguson, David J. P.;
Saunders, Jon R.;
Moxon, E. Richard

Publication type:

Article

Investigations into genome diversity of Haemophilus influenzae using whole genome sequencing of clinical isolates and laboratory transformants.

Published in:

BMC Microbiology, 2012, v. 12, n. 1, p. 273, doi. 10.1186/1471-2180-12-273

By:

Power, Peter M.;
Bentley, Stephen D.;
Parkhill, Julian;
Moxon, E. Richard;
Hood, Derek W.

Publication type:

Article

Dam inactivation in Neisseria meningitidis: prevalence among diverse hyperinvasive lineages.

Published in:

BMC Microbiology, 2004, v. 4, p. 1, doi. 10.1186/1471-2180-4-34

By:

Jolley, Keith A.;
Li Sun;
Moxon, E. Richard;
Maiden, Martin C. J.

Publication type:

Article

Glycine is a common substituentof the inner core in Haemophilus influenzaelipopolysaccharide.

Published in:

Glycobiology, 2001, v. 11, n. 12, p. 1009

By:

Li, Jianjun;
Bauer, SebastianH.J.;
Månsson, Martin;
Moxon, E. Richard;
Richards, James C.;
Schweda, Elke K.H.

Publication type:

Article

Genetic basis for expressionof the major globotetraose-containing lipopolysaccharide from H. influenzaestrain Rd (RM118).

Published in:

Glycobiology, 2001, v. 11, n. 11, p. 957, doi. 10.1093/glycob/11.11.957

By:

Hood, Derek W.;
Cox, Andrew D.;
Wakarchuk, Warren W.;
Schur, Melissa;
Schweda, Elke K.H.;
Walsh, Shannon L.;
Deadman, Mary E.;
Martin, Adele;
Moxon, E. Richard;
Richards, James C.

Publication type:

Article

Novel lipopolysaccharide biosynthetic genes containing tetranucleotide repeats in Haemophilus influenzae, identification of a gene for adding O-acetyl groups.

Published in:

Molecular Microbiology, 2005, v. 58, n. 1, p. 207, doi. 10.1111/j.1365-2958.2005.04814.x

By:

Fox, Kate L.;
Yildirim, Håkan H.;
Deadman, Mary E.;
Schweda, Elke K. H.;
Moxon, E. Richard;
Hood, Derek W.

Publication type:

Article

Antibody Concentration and Clinical Protection After Hib Conjugate Vaccination in the United Kingdom.

Published in:

JAMA: Journal of the American Medical Association, 2000, v. 284, n. 18, p. 2334, doi. 10.1001/jama.284.18.2334

By:

Heath, Paul T.;
Booy, Robert;
Azzopardi, Helen J.;
Slack, Mary P.E.;
Bowen-Morris, Jane;
Griffiths, Helen;
Ramsay, Mary E.;
Deeks, Jon J.;
Moxon, E. Richard

Publication type:

Article

Safety, Immunogenicity, and Induction of Immunologic Memory by a Serogroup C Meningococcal Conjugate Vaccine in Infants.

Published in:

JAMA: Journal of the American Medical Association, 2000, v. 283, n. 21, p. 2795, doi. 10.1001/jama.283.21.2795

By:

MacLennan, Jenny M.;
Shackley, Fiona;
Heath, Paul T.;
Deeks, Jonathan J.;
Flamank, Caroline;
Herbert, Mark;
Griffiths, Helen;
Hatzmann, Eva;
Goilav, Christian;
Moxon, E. Richard

Publication type:

Article

Capsulate bacteria and the lung.

Published in:

British Medical Bulletin, 2002, v. 61, n. 1, p. 63, doi. 10.1093/bmb/61.1.63

By:

Buttery, Jim;
Moxon, E. Richard

Publication type:

Article

Haemophilus influenzae Type b Vaccine Failure in Children Is Associated with Inadequate Production of High-Quality Antibody.

Published in:

Clinical Infectious Diseases, 2008, v. 46, n. 2, p. 186, doi. 10.1086/524668

By:

Yeh Chen Lee;
Kelly, Dominic F.;
Ly-Mee Yu;
Slack, Mary P. E.;
Booy, Robert;
Heath, Paul T.;
Siegrist, Claire-Anne;
Moxon, Richard E.;
Pollard, Andrew J.

Publication type:

Article

Serogroup C Meningococcal Glycoconjugate Vaccine in Adolescents: Persistence of Bactericidal Antibodies and Kinetics of the Immune Response to a Booster Vaccine More Than 3 Years after Immunization.

Published in:

Clinical Infectious Diseases, 2006, v. 43, n. 11, p. 1387, doi. 10.1086/508776

By:

Snape, Matthew D.;
Kelly, Dominic F.;
Salt, Penny;
Green, Sarah;
Snowden, Claire;
Diggle, Linda;
Borkowski, Astrid;
Ly-Mee Yu;
Moxon, E. Richard;
Pollard, Andrew J.

Publication type:

Article

The impact of conjugate vaccine on carriage of Haemophilus influenzae type b.

Published in:

1995

By:

Barbour, Marina L.;
Mayon-White, Richard T.;
Coles, Clare;
Crook, Derrick W. M.;
Moxon, E. Richard;
Barbour, M L;
Mayon-White, R T;
Coles, C;
Crook, D W;
Moxon, E R

Publication type:

journal article

Natural Genetic Transfer of a Putative Virulence-Enhancing Mutation to Haemophilus influenzae Type a.

Published in:

Journal of Infectious Diseases, 1994, v. 169, n. 3, p. 676, doi. 10.1093/infdis/169.3.676

By:

Kroll, J. Simon;
Moxon, E. Richard;
Loynds, Barbara M.

Publication type:

Article

Alteration of the Cell Wall of Haemophilus influenzae Type b by Transformation with Cloned DNA: Association with Attenuated Virulence.

Published in:

Journal of Infectious Diseases, 1985, v. 152, n. 3, p. 485, doi. 10.1093/infdis/152.3.485

By:

Zwahlen, André;
Rubin, Lorry G.;
Connelly, Carla J.;
Inzana, Thomas J.;
Moxon, E. Richard

Publication type:

Article

Role of Intravascular Replication in the Pathogenesis of Experimental Bacteremia Due to Haemophilus influenzae Type b.

Published in:

Journal of Infectious Diseases, 1985, v. 152, n. 2, p. 307, doi. 10.1093/infdis/152.2.307

By:

Rubin, Lorry G.;
Zwahlen, Andre;
Moxon, E. Richard

Publication type:

Article

Haemophilus influenzae Type b Colonization Resulting from Survival of a Single Organism.

Published in:

Journal of Infectious Diseases, 1984, v. 149, n. 2, p. 278, doi. 10.1093/infdis/149.2.278

By:

Rubin, Lorry G.;
Moxon, E. Richard

Publication type:

Article

Surface Determinants of Haemophilus influenzae Pathogenicity: Comparative Virulence of Capsular Transformants in Normal and Complement-Depleted Rats.

Published in:

Journal of Infectious Diseases, 1983, v. 148, n. 3, p. 385, doi. 10.1093/infdis/148.3.385

By:

Zwahlen, André;
Winkelstein, Jerry A.;
Moxon, E. Richard

Publication type:

Article

The Type b Capsular Polysaccharide as a Virulence Determinant of Haemophilus influenzae: Studies Using Clinical Isolates and Laboratory Transformants.

Published in:

Journal of Infectious Diseases, 1981, v. 143, n. 4, p. 517

By:

Moxon, E. Richard;
Vaughn, Karen A.

Publication type:

Article

Absence of Increasing Incidence of Meningitis Caused by Haemophilus influenzae Type b.

Published in:

Journal of Infectious Diseases, 1979, v. 140, n. 6, p. 1009

By:

Santosham, Mathuram;
Kallman, Clayton H.;
Neff, John M.;
Moxon, E. Richard

Publication type:

Article

Meningitis Caused by Haemophilus influenzae in Infant Rats: Protective Immunity and Antibody Priming by Gastrointestinal Colonization with Escherichia coli.

Published in:

Journal of Infectious Diseases, 1979, v. 140, n. 4, p. 471

By:

Moxon, E. Richard;
Anderson, Porter

Publication type:

Article