Works by MIYAZONO, Kohei

Results: 172

Treatment of childhood-onset cyclic neutropenia with recombinant human granulocyte colony-stimulating factor.

Published in:

European Journal of Haematology, 1990, v. 45, n. 2, p. 110, doi. 10.1111/j.1600-0609.1990.tb00428.x

By:

Sugunoto, Koichi;
Togawal, Atsushi;
Miyazono, Kohei;
Itoh, Katsuro;
Amano, Masamichi;
Chiba, Shigeru;
Hino, Masayuki;
Mizogu-chi, Hideaki;
Takaku, Fumimaro

Publication type:

Article

TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial--mesenchymal transition.

Published in:

Molecular Oncology, 2022, v. 16, n. 12, p. 2330, doi. 10.1002/1878-0261.13215

By:

Yutaro Tsubakihara;
Yae Ohata;
Yukari Okita;
Shady Younis;
Eriksson, Jens;
Sellin, Mikael E.;
Jiang Ren;
ten Dijke, Peter;
Kohei Miyazono;
Atsuhiko Hikita;
Takeshi Imamura;
Mitsuyasu Kato;
Carl-Henrik Heldin;
Moustakas, Aristidis

Publication type:

Article

Genome‐wide analysis of DNA methylation identifies the apoptosis‐related gene UQCRH as a tumor suppressor in renal cancer.

Published in:

Molecular Oncology, 2022, v. 16, n. 3, p. 732, doi. 10.1002/1878-0261.13040

By:

Miyakuni, Kosuke;
Nishida, Jun;
Koinuma, Daizo;
Nagae, Genta;
Aburatani, Hiroyuki;
Miyazono, Kohei;
Ehata, Shogo

Publication type:

Article

PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma‐initiating cell properties via DNA methyltransferase 3A.

Published in:

Molecular Oncology, 2022, v. 16, n. 1, p. 269, doi. 10.1002/1878-0261.13051

By:

Tanabe, Ryo;
Miyazono, Kohei;
Todo, Tomoki;
Saito, Nobuhito;
Iwata, Caname;
Komuro, Akiyoshi;
Sakai, Satoshi;
Raja, Erna;
Koinuma, Daizo;
Morikawa, Masato;
Westermark, Bengt;
Heldin, Carl‐Henrik

Publication type:

Article

Anti‐pyroptotic function of TGF‐β is suppressed by a synthetic dsRNA analogue in triple negative breast cancer cells.

Published in:

Molecular Oncology, 2021, v. 15, n. 5, p. 1289, doi. 10.1002/1878-0261.12890

By:

Tamura, Yusuke;
Morikawa, Masato;
Tanabe, Ryo;
Miyazono, Kohei;
Koinuma, Daizo

Publication type:

Article

Neurotensin receptor 1 signaling promotes pancreatic cancer progression.

Published in:

Molecular Oncology, 2021, v. 15, n. 1, p. 151, doi. 10.1002/1878-0261.12815

By:

Takahashi, Kei;
Ehata, Shogo;
Miyauchi, Kensuke;
Morishita, Yasuyuki;
Miyazawa, Keiji;
Miyazono, Kohei

Publication type:

Article

Comparative analysis of TTF‐1 binding DNA regions in small‐cell lung cancer and non‐small‐cell lung cancer.

Published in:

Molecular Oncology, 2020, v. 14, n. 2, p. 277, doi. 10.1002/1878-0261.12608

By:

Hokari, Satoshi;
Tamura, Yusuke;
Kaneda, Atsushi;
Katsura, Akihiro;
Morikawa, Masato;
Murai, Fumihiko;
Ehata, Shogo;
Tsutsumi, Shuichi;
Ishikawa, Yuichi;
Aburatani, Hiroyuki;
Kikuchi, Toshiaki;
Miyazono, Kohei;
Koinuma, Daizo

Publication type:

Article

Fibroblast growth factor signals regulate transforming growth factor‐β‐induced endothelial‐to‐myofibroblast transition of tumor endothelial cells via Elk1.

Published in:

Molecular Oncology, 2019, v. 13, n. 8, p. 1706, doi. 10.1002/1878-0261.12504

By:

Akatsu, Yuichi;
Takahashi, Naoya;
Yoshimatsu, Yasuhiro;
Kimuro, Shiori;
Muramatsu, Tomoki;
Katsura, Akihiro;
Maishi, Nako;
Suzuki, Hiroshi I.;
Inazawa, Johji;
Hida, Kyoko;
Miyazono, Kohei;
Watabe, Tetsuro

Publication type:

Article

ZEB1-regulated inflammatory phenotype in breast cancer cells.

Published in:

Molecular Oncology, 2017, v. 11, n. 9, p. 1241, doi. 10.1002/1878-0261.12098

By:

Katsura, Akihiro;
Tamura, Yusuke;
Hokari, Satoshi;
Harada, Mayumi;
Morikawa, Masato;
Sakurai, Tsubasa;
Takahashi, Kei;
Mizutani, Anna;
Nishida, Jun;
Yokoyama, Yuichiro;
Morishita, Yasuyuki;
Murakami, Takashi;
Ehata, Shogo;
Miyazono, Kohei;
Koinuma, Daizo

Publication type:

Article

Apoptosis inhibitory activity of cytoplasmic p21<sup>Cip1/WAF1</sup> in monocytic differentiation.

Published in:

EMBO Journal, 1999, v. 18, n. 5, p. 1223, doi. 10.1093/emboj/18.5.1223

By:

Asada, Minoru;
Yamada, Takayuki;
Ichijo, Hidenori;
Delia, Domenico;
Miyazono, Kohei;
Fukumuro, Kenji;
Mizutani, Shuki

Publication type:

Article

Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors.

Published in:

EMBO Journal, 1998, v. 17, n. 14, p. 4056, doi. 10.1093/emboj/17.14.4056

By:

Kawabata, Masahiro;
Inoue, Hirofumi;
Hanyu, Aki;
Imamura, Takeshi;
Miyazono, Kohei

Publication type:

Article

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

Published in:

EMBO Journal, 1998, v. 17, n. 9, p. 2596, doi. 10.1093/emboj/17.9.2596

By:

Saitoh, Masao;
Nishitoh, Hideki;
Fujii, Makiko;
Takeda, Kohsuke;
Tobiume, Kei;
Sawada, Yasuhiro;
Kawabata, Masahiro;
Miyazono, Kohei;
Ichijo, Hidenori

Publication type:

Article

Phosphorylation of Ser165 in TGF-ß type I receptor modulates TGF-ß1-induced cellular responses.

Published in:

1997

By:

Souchelnytskyi, Serhiy;
ten Dijke, Peter;
Miyazono, Kohei;
Heldin, Carl-Henrik

Publication type:

Correction Notice

TGF-ß receptor-mediated signalling through Smad2, Smad3 and Smad4.

Published in:

EMBO Journal, 1997, v. 16, n. 17, p. 5353, doi. 10.1093/emboj/16.17.5353

By:

Nakao, Atsuhito;
Imamura, Takeshi;
Souchelnytskyi, Serhiy;
Kawabata, Masahiro;
Ishisaki, Akira;
Oeda, Eiichi;
Tamaki, Kiyoshi;
Hanai, Jun-ichi;
Heldin, Carl-Henrik;
Miyazono, Kohei;
ten Dijke, Peter

Publication type:

Article

PolyI:C attenuates transforming growth factor‐β signaling to induce cytostasis of surrounding cells by secreted factors in triple‐negative breast cancer.

Published in:

Cancer Science, 2022, v. 113, n. 3, p. 940, doi. 10.1111/cas.15241

By:

Tamura, Yusuke;
Tsutsumi, Shuichi;
Miyazono, Kohei;
Koinuma, Daizo

Publication type:

Article

Visualization of the cancer cell cycle by tissue‐clearing technology using the Fucci reporter system.

Published in:

Cancer Science, 2021, v. 112, n. 9, p. 3796, doi. 10.1111/cas.15034

By:

Takahashi, Kei;
Tanabe, Ryo;
Ehata, Shogo;
Kubota, Shimpei I.;
Morishita, Yasuyuki;
Ueda, Hiroki R.;
Miyazono, Kohei

Publication type:

Article

Heterogenous expression of endoglin marks advanced renal cancer with distinct tumor microenvironment fitness.

Published in:

Cancer Science, 2021, v. 112, n. 8, p. 3136, doi. 10.1111/cas.15007

By:

Momoi, Yusaku;
Nishida, Jun;
Miyakuni, Kosuke;
Kuroda, Masafumi;
Kubota, Shimpei I.;
Miyazono, Kohei;
Ehata, Shogo

Publication type:

Article

TNF‐α enhances TGF‐β‐induced endothelial‐to‐mesenchymal transition via TGF‐β signal augmentation.

Published in:

Cancer Science, 2020, v. 111, n. 7, p. 2385, doi. 10.1111/cas.14455

By:

Yoshimatsu, Yasuhiro;
Wakabayashi, Ikumi;
Kimuro, Shiori;
Takahashi, Naoya;
Takahashi, Kazuki;
Kobayashi, Miho;
Maishi, Nako;
Podyma‐Inoue, Katarzyna A.;
Hida, Kyoko;
Miyazono, Kohei;
Watabe, Tetsuro

Publication type:

Article

Tyrosine kinase Eph receptor A6 sensitizes glioma‐initiating cells towards bone morphogenetic protein‐induced apoptosis.

Published in:

Cancer Science, 2019, v. 110, n. 11, p. 3486, doi. 10.1111/cas.14187

By:

Raja, Erna;
Morikawa, Masato;
Nishida, Jun;
Tanabe, Ryo;
Takahashi, Kei;
Seeherman, Howard J.;
Saito, Nobuhito;
Todo, Tomoki;
Miyazono, Kohei

Publication type:

Article

c‐Ski accelerates renal cancer progression by attenuating transforming growth factor β signaling.

Published in:

Cancer Science, 2019, v. 110, n. 6, p. 2063, doi. 10.1111/cas.14018

By:

Taguchi, Luna;
Miyakuni, Kosuke;
Morishita, Yasuyuki;
Morikawa, Teppei;
Fukayama, Masashi;
Miyazono, Kohei;
Ehata, Shogo

Publication type:

Article

Palbociclib enhances activin‐SMAD‐induced cytostasis in estrogen receptor‐positive breast cancer.

Published in:

Cancer Science, 2019, v. 110, n. 1, p. 209, doi. 10.1111/cas.13841

By:

Harada, Mayumi;
Morikawa, Masato;
Ozawa, Takayuki;
Kobayashi, Mai;
Tamura, Yusuke;
Takahashi, Kei;
Tanabe, Masahiko;
Tada, Keiichiro;
Seto, Yasuyuki;
Miyazono, Kohei;
Koinuma, Daizo

Publication type:

Article

Long noncoding RNA NORAD regulates transforming growth factor‐β signaling and epithelial‐to‐mesenchymal transition‐like phenotype.

Published in:

Cancer Science, 2018, v. 109, n. 7, p. 2211, doi. 10.1111/cas.13626

By:

Kawasaki, Natsumi;
Miwa, Toshiki;
Hokari, Satoshi;
Sakurai, Tsubasa;
Ohmori, Kazuho;
Miyauchi, Kensuke;
Miyazono, Kohei;
Koinuma, Daizo

Publication type:

Article

Dual targeting of vascular endothelial growth factor and bone morphogenetic protein-9/10 impairs tumor growth through inhibition of angiogenesis.

Published in:

Cancer Science, 2017, v. 108, n. 1, p. 151, doi. 10.1111/cas.13103

By:

Akatsu, Yuichi;
Yoshimatsu, Yasuhiro;
Tomizawa, Taishi;
Takahashi, Kazuki;
Katsura, Akihiro;
Miyazono, Kohei;
Watabe, Tetsuro

Publication type:

Article

A clinically attainable dose of L-asparaginase targets glutamine addiction in lymphoid cell lines.

Published in:

Cancer Science, 2015, v. 106, n. 11, p. 1534, doi. 10.1111/cas.12807

By:

Sugimoto, Koichi;
Suzuki, Hiroshi I.;
Fujimura, Tsutomu;
Ono, Asami;
Kaga, Naoko;
Isobe, Yasushi;
Sasaki, Makoto;
Taka, Hikari;
Miyazono, Kohei;
Komatsu, Norio

Publication type:

Article

Subcellular localization of Lin28A.

Published in:

2015

By:

Suzuki, Hiroshi I.;
Katsura, Akihiro;
Miyazono, Kohei

Publication type:

Other

A role of uridylation pathway for blockade of let-7 micro RNA biogenesis by Lin28B.

Published in:

Cancer Science, 2015, v. 106, n. 9, p. 1174, doi. 10.1111/cas.12721

By:

Suzuki, Hiroshi I.;
Katsura, Akihiro;
Miyazono, Kohei

Publication type:

Article

Roles of PDGFRβ signals in lymphangiogenesis. Blood vascular and lymphatic vessels in xenograft tumors derived from BxPC3 human pancreatic adenocarcinoma cells were visualized by immunofluorescence staining for PECAM-1 (green) and LYVE-1 (red), respectively, followed by counterstaining with TOTO-3 (blue) to visualize nuclei

Published in:

2014

By:

Miyazaki, Hideki;
Yoshimatsu, Yasuhiro;
Akatsu, Yuichi;
Mishima, Koichi;
Fukayama, Masashi;
Watabe, Tetsuro;
Miyazono, Kohei

Publication type:

Other

Expression of platelet-derived growth factor receptor β is maintained by Prox1 in lymphatic endothelial cells and is required for tumor lymphangiogenesis.

Published in:

Cancer Science, 2014, v. 105, n. 9, p. 1116, doi. 10.1111/cas.12476

By:

Miyazaki, Hideki;
Yoshimatsu, Yasuhiro;
Akatsu, Yuichi;
Mishima, Koichi;
Fukayama, Masashi;
Watabe, Tetsuro;
Miyazono, Kohei

Publication type:

Article

Transforming growth factor-β-induced lnc RNA-Smad7 inhibits apoptosis of mouse breast cancer Jyg MC(A) cells.

Published in:

Cancer Science, 2014, v. 105, n. 8, p. 974, doi. 10.1111/cas.12454

By:

Arase, Mayu;
Horiguchi, Kana;
Ehata, Shogo;
Morikawa, Masato;
Tsutsumi, Shuichi;
Aburatani, Hiroyuki;
Miyazono, Kohei;
Koinuma, Daizo

Publication type:

Article

Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes.

Published in:

Cancer Science, 2013, v. 104, n. 9, p. 1189, doi. 10.1111/cas.12220

By:

Shirakihara, Takuya;
Kawasaki, Tomonori;
Fukagawa, Akihiko;
Semba, Kentaro;
Sakai, Ryuichi;
Miyazono, Kohei;
Miyazawa, Keiji;
Saitoh, Masao

Publication type:

Article

Report of the Japan Diabetes Society/ Japanese Cancer Association joint committee on diabetes and cancer.

Published in:

Cancer Science, 2013, v. 104, n. 7, p. 965, doi. 10.1111/cas.12203

By:

Kasuga, Masato;
Ueki, Kohjiro;
Tajima, Naoko;
Noda, Mitsuhiko;
Ohashi, Ken;
Noto, Hiroshi;
Goto, Atsushi;
Ogawa, Wataru;
Sakai, Ryuichi;
Tsugane, Shoichiro;
Hamajima, Nobuyuki;
Nakagama, Hitoshi;
Tajima, Kazuo;
Miyazono, Kohei;
Imai, Kohzoh

Publication type:

Article

Molecular mechanisms of transforming growth factor-β signaling and disease: The 59th Fujihara International Seminar, 2010.

Published in:

Cancer Science, 2011, v. 102, n. 6, p. 1242, doi. 10.1111/j.1349-7006.2010.01806.x

By:

Miyazono, Kohei

Publication type:

Article

Exogenous introduction of tissue inhibitor of metalloproteinase 2 reduces accelerated growth of TGF-β-disrupted diffuse-type gastric carcinoma.

Published in:

Cancer Science, 2010, v. 101, n. 11, p. 2398, doi. 10.1111/j.1349-7006.2010.01688.x

By:

Johansson, Erik;
Komuro, Akiyoshi;
Iwata, Caname;
Hagiwara, Akifumi;
Fuse, Yuma;
Watanabe, Akira;
Morishita, Yasuyuki;
Aburatani, Hiroyuki;
Funa, Keiko;
Kano, Mitsunobu R.;
Miyazono, Kohei

Publication type:

Article

Cellular context-dependent “colors” of transforming growth factor-β signaling.

Published in:

Cancer Science, 2010, v. 101, n. 2, p. 306, doi. 10.1111/j.1349-7006.2009.01441.x

By:

Ikushima, Hiroaki;
Miyazono, Kohei

Publication type:

Article

Promoter-wide analysis of Smad4 binding sites in human epithelial cells.

Published in:

Cancer Science, 2009, v. 100, n. 11, p. 2133, doi. 10.1111/j.1349-7006.2009.01299.x

By:

Koinuma, Daizo;
Tsutsumi, Shuichi;
Kamimura, Naoko;
Imamura, Takeshi;
Aburatani, Hiroyuki;
Miyazono, Kohei

Publication type:

Article

c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-β signaling in diffuse-type gastric carcinoma.

Published in:

Cancer Science, 2009, v. 100, n. 10, p. 1809, doi. 10.1111/j.1349-7006.2009.01248.x

By:

Kiyono, Kunihiko;
Suzuki, Hiroshi I.;
Morishita, Yasuyuki;
Komuro, Akiyoshi;
Iwata, Caname;
Yashiro, Masakazu;
Hirakawa, Kosei;
Kano, Mitsunobu R.;
Miyazono, Kohei

Publication type:

Article

Transforming growth factor-β signaling and cancer: The 28th Sapporo Cancer Seminar, 25–27 June 2008.

Published in:

2009

By:

Miyazono, Kohei

Publication type:

Report

Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-β receptor inhibitor on extravasation of nanoparticles from neovasculature.

Published in:

Cancer Science, 2009, v. 100, n. 1, p. 173, doi. 10.1111/j.1349-7006.2008.01003.x

By:

Kano, Mitsunobu R.;
Komuta, Yukari;
Iwata, Caname;
Oka, Masako;
Shirai, Yo-taro;
Morishita, Yasuyuki;
Ouchi, Yasuyoshi;
Kataoka, Kazunori;
Miyazono, Kohei

Publication type:

Article

Ki26894, a novel transforming growth factor-β type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.

Published in:

Cancer Science, 2007, v. 98, n. 1, p. 127, doi. 10.1111/j.1349-7006.2006.00357.x

By:

Ehata, Shogo;
Hanyu, Aki;
Fujime, Makoto;
Katsuno, Yoko;
Fukunaga, Erina;
Goto, Kouichiro;
Ishikawa, Yuichi;
Nomura, Kimie;
Yokoo, Hiroshi;
Shimizu, Toshiyuki;
Ogata, Etsuro;
Miyazono, Kohei;
Shimizu, Kiyoshi;
Imamura, Takeshi

Publication type:

Article

Tenth Japanese-German Workshop on Molecular and Cellular Aspects of Carcinogenesis, Essen, Germany, 29 September–1 October 2005.

Published in:

2006

By:

Miyazono, Kohei;
Ishikawa, Fuyuki;
Winterhager, Elke;
Deppert, Wolfgang;
Rajewsky, Manfred F.

Publication type:

Report

The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-β.

Published in:

Cancer Science, 2005, v. 96, n. 11, p. 791, doi. 10.1111/j.1349-7006.2005.00103.x

By:

Tojo, Masayoshi;
Hamashima, Yoshio;
Hanyu, Aki;
Kajimoto, Tetsuya;
Saitoh, Masao;
Miyazono, Kohei;
Node, Manabu;
Imamura, Takeshi

Publication type:

Article

Ninth Japanese-German Workshop on Molecular and Cellular Aspects of Carcinogenesis, Essen, Germany, 18-20 September, 2003.

Published in:

Cancer Science, 2004, v. 95, n. 3, p. 276, doi. 10.1111/j.1349-7006.2004.tb02216.x

By:

Miyazono, Kohei;
Ishikawa, Fuyuki;
Winterhager, Elke;
Deppert, Wolfgang;
Rajewsky, Manfred F.

Publication type:

Article

Transforming growth factor-β signaling is differentially inhibited by Smad2D450E and Smad3D407E.

Published in:

Cancer Science, 2004, v. 95, n. 1, p. 12, doi. 10.1111/j.1349-7006.2004.tb03164.x

By:

Kondo, Miki;
Suzuki, Hiroyuki;
Takehara, Kazuhiko;
Miyazono, Kohei;
Kato, Mitsuyasu

Publication type:

Article

Obituary.

Published in:

Cancer Science, 2003, v. 94, n. 10, p. 929, doi. 10.1111/j.1349-7006.2003.tb01378.x

By:

Miyazono, Kohei

Publication type:

Article

Regulation of TGF-β signaling and its roles in progression of tumors.

Published in:

Cancer Science, 2003, v. 94, n. 3, p. 230, doi. 10.1111/j.1349-7006.2003.tb01425.x

By:

Miyazono, Kohei;
Suzuki, Hiroyuki;
Imamura, Takeshi

Publication type:

Article

Targets of Transcriptional Regulation by Transforming Growth Factor-β: Expression Profile Analysis Using Oligonucleotide Arrays.

Published in:

Cancer Science, 2001, v. 92, n. 3, p. 257, doi. 10.1111/j.1349-7006.2001.tb01090.x

By:

Akiyoshi, Shingo;
Ishii, Masami;
Nemoto, Nobuo;
Kawabata, Masahiro;
Aburatani, Hiroyuki;
Miyazono, Kohei

Publication type:

Article

TGF-β signal transduction spreading to a wider field: a broad variety of mechanisms for context-dependent effects of TGF-β.

Published in:

Cell & Tissue Research, 2012, v. 347, n. 1, p. 37, doi. 10.1007/s00441-011-1179-5

By:

Ikushima, Hiroaki;
Miyazono, Kohei

Publication type:

Article

Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01786-y

By:

Kubota, Shimpei I.;
Takahashi, Kei;
Mano, Tomoyuki;
Matsumoto, Katsuhiko;
Katsumata, Takahiro;
Shi, Shoi;
Tainaka, Kazuki;
Ueda, Hiroki R.;
Ehata, Shogo;
Miyazono, Kohei

Publication type:

Article

BMP signaling is a therapeutic target in ovarian cancer.

Published in:

Cell Death Discovery, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41420-020-00377-w

By:

Fukuda, Tomohiko;
Fukuda, Risa;
Tanabe, Ryo;
Koinuma, Daizo;
Koyama, Hiroo;
Hashizume, Yoshinobu;
Moustakas, Aristidis;
Miyazono, Kohei;
Heldin, Carl-Henrik

Publication type:

Article

Bi-directional roles of bone morphogenetic proteins in cancer: Another molecular Jekyll and Hyde?

Published in:

Pathology International, 2013, v. 63, n. 6, p. 287, doi. 10.1111/pin.12067

By:

Ehata, Shogo;
Yokoyama, Yuichiro;
Takahashi, Kei;
Miyazono, Kohei

Publication type:

Article