Works by MARCHETTI, PIERO

Results: 202

From genotype to human β cell phenotype and beyond.

Published in:

Islets, 2012, v. 4, n. 5, p. 323, doi. 10.4161/isl.22282

By:

Marchetti, Piero;
Syed, Farooq;
Suleiman, Mara;
Bugliani, Marco;
Marselli, Lorella

Publication type:

Article

A patient with MEN1 and end-stage chronic kidney disease due to Alport syndrome: Decision making on the eligibility of transplantation.

Published in:

Molecular & Clinical Oncology, 2018, v. 8, n. 3, p. 449, doi. 10.3892/mco.2017.1542

By:

Matrone, Antonio;
Brancatella, Alessandro;
Marchetti, Piero;
Vasile, Enrico;
Boggi, Ugo;
Elisei, Rossella;
Cetani, Filomena;
Marcocci, Claudio;
Vitti, Paolo;
Latrofa, Francesco

Publication type:

Article

SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β -Cells and in the Human Pancreas Microvasculature.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.596898

By:

Fignani, Daniela;
Licata, Giada;
Brusco, Noemi;
Nigi, Laura;
Grieco, Giuseppina E.;
Marselli, Lorella;
Overbergh, Lut;
Gysemans, Conny;
Colli, Maikel L.;
Marchetti, Piero;
Mathieu, Chantal;
Eizirik, Decio L.;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.

Published in:

Cell Death & Disease, 2018, v. 9, n. 3, p. 1, doi. 10.1038/s41419-018-0272-z

By:

Mellado-Gil, Jose M.;
Fuente-Martín, Esther;
Lorenzo, Petra I.;
Cobo-Vuilleumier, Nadia;
López-Noriega, Livia;
Martín-Montalvo, Alejandro;
Gómez, Irene de Gracia Herrera;
Ceballos-Chávez, Maria;
Gómez-Jaramillo, Laura;
Campos-Caro, Antonio;
Romero-Zerbo, Silvana Y.;
Rodríguez-Comas, Júlia;
Servitja, Joan-Marc;
Rojo-Martinez, Gemma;
Hmadcha, Abdelkrim;
Soria, Bernat;
Bugliani, Marco;
Marchetti, Piero;
Bérmudez-Silva, Francisco J.;
Reyes, Jose C.

Publication type:

Article

Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation.

Published in:

Cell Death & Disease, 2016, v. 7, n. 8, p. e2329, doi. 10.1038/cddis.2016.203

By:

Bagnati, Marta;
Ogunkolade, Babatunji W;
Marshall, Catriona;
Tucci, Carmen;
Hanna, Katie;
Jones, Tania A;
Bugliani, Marco;
Nedjai, Belinda;
Caton, Paul W;
Kieswich, Julius;
Yaqoob, Muhammed M;
Ball, Graham R;
Marchetti, Piero;
Hitman, Graham A;
Turner, Mark D

Publication type:

Article

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.

Published in:

2009

By:

Prudente, Sabrina;
Scarpelli, Daniela;
Chandalia, Manisha;
Zhang, Yuan-Yuan;
Morini, Eleonora;
Del Guerra, Silvia;
Perticone, Francesco;
Li, Rong;
Powers, Christine;
Andreozzi, Francesco;
Marchetti, Piero;
Dallapiccola, Bruno;
Abate, Nicola;
Doria, Alessandro;
Sesti, Giorgio;
Trischitta, Vincenzo

Publication type:

journal article

The E23K Variant of KCNJ11 Encoding the Pancreatic β-Cell Adenosine 5β-Triphosphate-Sensitive Potassium Channel Subunit Kir6.2 Is Associated with an Increased Risk of Secondary Failure to Sulfonylurea in Patients with Type 2 Diabetes.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 6, p. 2334, doi. 10.1210/jc.2005-2323

By:

Sesti, Giorgio;
Laratta, Emanuela;
Cardellini, Marina;
Andreozzi, Francesco;
Guerra, Silvia Del;
Irace, Concetta;
Gnasso, Agostino;
Grupillo, Maria;
Lauro, Renato;
Letizia Hribal, Marta;
Perticone, Francesco;
Marchetti, Piero

Publication type:

Article

Pancreatic Islets from Type 2 Diabetic Patients Have Functional Defects and Increased Apoptosis That Are Ameliorated by Metformin.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 11, p. 5535, doi. 10.1210/jc.2004-0150

By:

MARCHETTI, PIERO;
DEL GUERRA, SILVIA;
MARSELLI, LORELLA;
LUPI, ROBERTO;
MASINI, MATILDE;
POLLERA, MARIA;
BUGLIANI, MARCO;
BOGGI, UGO;
VISTOLI, FABIO;
MOSCA, FRANCO;
DEL PRATO, STEFANO

Publication type:

Article

Th2 Cytokines Have a Partial, Direct Protective Effect on the Function and Survival of Isolated Human Islets Exposed to Combined Proinflammatory and Th1 Cytokines.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 2, p. 4974, doi. 10.1210/jcem.86.10.7938

By:

MARSELLI, LORELLA;
DOTTA, FRANCESCO;
PIRO, SALVATORE;
SANTANGELO, CARMELA;
MASINI, MATILDE;
LUPI, ROBERTO;
REALACCI, MASSIMO;
GUERRA, SILVIA DEL;
MOSCA, FRANCO;
BOGGI, UGO;
PURRELLO, FRANCESCO;
NAVALESI, RENZO;
MARCHETTI, PIERO

Publication type:

Article

Pancreas rejection after pandemic influenzavirus A(H.

Published in:

Transplant International, 2011, v. 24, n. 3, p. e28, doi. 10.1111/j.1432-2277.2010.01193.x

By:

Fabio, Vistoli;
Daniele, Focosi;
Monica, De Donno;
Simone, Giannecchini;
Luciana, Mariotti Maria;
Margherita, Occhipinti;
Massimiliano, Barsotti;
Rene, Duquesnoy;
Piero, Marchetti;
Fabrizio, Scatena;
Ugo, Boggi

Publication type:

Article

Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death.

Published in:

Diabetologia, 2023, v. 66, n. 8, p. 1544, doi. 10.1007/s00125-023-05908-5

By:

Roca-Rivada, Arturo;
Marín-Cañas, Sandra;
Colli, Maikel L.;
Vinci, Chiara;
Sawatani, Toshiaki;
Marselli, Lorella;
Cnop, Miriam;
Marchetti, Piero;
Eizirik, Decio L.

Publication type:

Article

A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice.

Published in:

Diabetologia, 2020, v. 63, n. 4, p. 825, doi. 10.1007/s00125-019-05068-5

By:

Demine, Stéphane;
Garcia Ribeiro, Rita;
Thevenet, Julien;
Marselli, Lorella;
Marchetti, Piero;
Pattou, François;
Kerr-Conte, Julie;
Devoogdt, Nick;
Eizirik, Decio L.

Publication type:

Article

Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.

Published in:

Diabetologia, 2020, v. 63, n. 2, p. 395, doi. 10.1007/s00125-019-05046-x

By:

Oshima, Masaya;
Pechberty, Séverine;
Bellini, Lara;
Göpel, Sven O.;
Campana, Mélanie;
Rouch, Claude;
Dairou, Julien;
Cosentino, Cristina;
Fantuzzi, Federica;
Toivonen, Sanna;
Marchetti, Piero;
Magnan, Christophe;
Cnop, Miriam;
Le Stunff, Hervé;
Scharfmann, Raphaël

Publication type:

Article

Fostering improved human islet research: a European perspective.

Published in:

2019

By:

Marchetti, Piero;
Schulte, Anke M.;
Marselli, Lorella;
Schoniger, Eyke;
Bugliani, Marco;
Kramer, Werner;
Overbergh, Lut;
Ullrich, Susanne;
Gloyn, Anna L.;
Ibberson, Mark;
Rutter, Guy;
Froguel, Philippe;
Groop, Leif;
McCarthy, Mark I.;
Dotta, Francesco;
Scharfmann, Raphael;
Magnan, Christophe;
Eizirik, Decio L.;
Mathieu, Chantal;
Cnop, Miriam

Publication type:

Letter

A call for improved reporting of human islet characteristics in research articles.

Published in:

Diabetologia, 2019, v. 62, n. 2, p. 209, doi. 10.1007/s00125-018-4784-y

By:

Poitout, Vincent;
Satin, Leslie S.;
Kahn, Steven E.;
Stoffers, Doris A.;
Marchetti, Piero;
Gannon, Maureen;
Verchere, C. Bruce;
Herold, Kevan C.;
Myers, Martin G.;
Marshall, Sally M.

Publication type:

Article

Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.

Published in:

Diabetologia, 2018, v. 61, n. 8, p. 1780, doi. 10.1007/s00125-018-4629-8

By:

Bellini, Lara;
Campana, Mélanie;
Rouch, Claude;
Chacinska, Marta;
Bugliani, Marco;
Meneyrol, Kelly;
Hainault, Isabelle;
Lenoir, Véronique;
Denom, Jessica;
Véret, Julien;
Kassis, Nadim;
Thorens, Bernard;
Ibberson, Mark;
Marchetti, Piero;
Blachnio-Zabielska, Agnieszka;
Cruciani-Guglielmacci, Céline;
Prip-Buus, Carina;
Magnan, Christophe;
Le Stunff, Hervé

Publication type:

Article

IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells.

Published in:

Diabetologia, 2018, v. 61, n. 3, p. 636, doi. 10.1007/s00125-017-4536-4

By:

Coomans de Brachène, Alexandra;
Dos Santos, Reinaldo S.;
Marroqui, Laura;
Colli, Maikel L.;
Marselli, Lorella;
Mirmira, Raghavendra G.;
Marchetti, Piero;
Eizirik, Decio L.

Publication type:

Article

Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes.

Published in:

Diabetologia, 2017, v. 60, n. 4, p. 656, doi. 10.1007/s00125-016-4201-3

By:

Marroqui, Laura;
Dos Santos, Reinaldo;
Op de beeck, Anne;
Coomans de Brachène, Alexandra;
Marselli, Lorella;
Marchetti, Piero;
Eizirik, Decio

Publication type:

Article

Islet inflammation in type 2 diabetes.

Published in:

2016

By:

Marchetti, Piero

Publication type:

Letter

Mast cells infiltrate pancreatic islets in human type 1 diabetes.

Published in:

Diabetologia, 2015, v. 58, n. 11, p. 2554, doi. 10.1007/s00125-015-3734-1

By:

Martino, Luisa;
Masini, Matilde;
Bugliani, Marco;
Marselli, Lorella;
Suleiman, Mara;
Boggi, Ugo;
Nogueira, Tatiane;
Filipponi, Franco;
Occhipinti, Margherita;
Campani, Daniela;
Dotta, Francesco;
Syed, Farooq;
Eizirik, Decio;
Marchetti, Piero;
Tata, Vincenzo

Publication type:

Article

Erratum to: The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.

Published in:

2015

By:

Natalicchio, Annalisa;
Tortosa, Federica;
Labarbuta, Rossella;
Biondi, Giuseppina;
Marrano, Nicola;
Carchia, Emanuele;
Leonardini, Anna;
Cignarelli, Angelo;
Bugliani, Marco;
Marchetti, Piero;
Fadini, Gian;
Giorgio, Marco;
Avogaro, Angelo;
Perrini, Sebastio;
Laviola, Luigi;
Giorgino, Francesco

Publication type:

Erratum

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.

Published in:

Diabetologia, 2015, v. 58, n. 10, p. 2307, doi. 10.1007/s00125-015-3669-6

By:

Brozzi, Flora;
Nardelli, Tarlliza;
Lopes, Miguel;
Millard, Isabelle;
Barthson, Jenny;
Igoillo-Esteve, Mariana;
Grieco, Fabio;
Villate, Olatz;
Oliveira, Joana;
Casimir, Marina;
Bugliani, Marco;
Engin, Feyza;
Hotamisligil, Gökhan;
Marchetti, Piero;
Eizirik, Decio

Publication type:

Article

The p66 redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.

Published in:

Diabetologia, 2015, v. 58, n. 6, p. 1260, doi. 10.1007/s00125-015-3563-2

By:

Natalicchio, Annalisa;
Tortosa, Federica;
Labarbuta, Rossella;
Biondi, Giuseppina;
Marrano, Nicola;
Carchia, Emanuele;
Leonardini, Anna;
Cignarelli, Angelo;
Bugliani, Marco;
Marchetti, Piero;
Fadini, Gian;
Giorgio, Marco;
Avogaro, Angelo;
Perrini, Sebastio;
Laviola, Luigi;
Giorgino, Francesco

Publication type:

Article

Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes.

Published in:

Diabetologia, 2014, v. 57, n. 9, p. 1876, doi. 10.1007/s00125-014-3299-4

By:

Omar, Bilal;
Liehua, Liu;
Yamada, Yuchiro;
Seino, Yutaka;
Marchetti, Piero;
Ahrén, B.

Publication type:

Article

Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1- iddm rat and humans with type 1 diabetes.

Published in:

Diabetologia, 2014, v. 57, n. 3, p. 512, doi. 10.1007/s00125-013-3125-4

By:

Jörns, Anne;
Arndt, Tanja;
Vilsendorf, Andreas;
Klempnauer, Jürgen;
Wedekind, Dirk;
Hedrich, Hans-Jürgen;
Marselli, Lorella;
Marchetti, Piero;
Harada, Nagakatsu;
Nakaya, Yutaka;
Wang, Gen-Sheng;
Scott, Fraser;
Gysemans, Conny;
Mathieu, Chantal;
Lenzen, Sigurd

Publication type:

Article

IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets.

Published in:

Diabetologia, 2014, v. 57, n. 3, p. 502, doi. 10.1007/s00125-013-3135-2

By:

Grieco, Fabio;
Moore, Fabrice;
Vigneron, François;
Santin, Izortze;
Villate, Olatz;
Marselli, Lorella;
Rondas, Dieter;
Korf, Hannelie;
Overbergh, Lutgart;
Dotta, Francesco;
Marchetti, Piero;
Mathieu, Chantal;
Eizirik, Décio

Publication type:

Article

Are we overestimating the loss of beta cells in type 2 diabetes?

Published in:

Diabetologia, 2014, v. 57, n. 2, p. 362, doi. 10.1007/s00125-013-3098-3

By:

Marselli, Lorella;
Suleiman, Mara;
Masini, Matilde;
Campani, Daniela;
Bugliani, Marco;
Syed, Farooq;
Martino, Luisa;
Focosi, Daniele;
Scatena, Fabrizio;
Olimpico, Francesco;
Filipponi, Franco;
Masiello, Pellegrino;
Boggi, Ugo;
Marchetti, Piero

Publication type:

Article

Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway.

Published in:

Diabetologia, 2013, v. 56, n. 11, p. 2456, doi. 10.1007/s00125-013-3028-4

By:

Natalicchio, Annalisa;
Labarbuta, Rossella;
Tortosa, Federica;
Biondi, Giuseppina;
Marrano, Nicola;
Peschechera, Alessandro;
Carchia, Emanuele;
Orlando, Maura;
Leonardini, Anna;
Cignarelli, Angelo;
Marchetti, Piero;
Perrini, Sebastio;
Laviola, Luigi;
Giorgino, Francesco

Publication type:

Article

In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist.

Published in:

Diabetes, Obesity & Metabolism, 2022, v. 24, n. 11, p. 2090, doi. 10.1111/dom.14794

By:

Jones, Ben;
Burade, Vinod;
Akalestou, Elina;
Manchanda, Yusman;
Ramchunder, Zenouska;
Carrat, Gaëlle;
Nguyen‐Tu, Marie‐Sophie;
Marchetti, Piero;
Piemonti, Lorenzo;
Leclerc, Isabelle;
Thennati, Rajamannar;
Vilsboll, Tina;
Thorens, Bernard;
Tomas, Alejandra;
Rutter, Guy A.

Publication type:

Article

Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta‐cell protection in type 1 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2020, v. 22, n. 10, p. 1827, doi. 10.1111/dom.14104

By:

Coomans de Brachène, Alexandra;
Castela, Angela;
Op de Beeck, Anne;
Mirmira, Raghavendra G.;
Marselli, Lorella;
Marchetti, Piero;
Masse, Craig;
Miao, Wenyan;
Leit, Silvana;
Evans‐Molina, Carmella;
Eizirik, Decio L.

Publication type:

Article

Coxsackievirus B Tailors the Unfolded Protein Response to Favour Viral Amplification in Pancreatic β Cells.

Published in:

Journal of Innate Immunity, 2019, v. 11, n. 4, p. 375, doi. 10.1159/000496034

By:

Colli, Maikel L.;
Paula, Flavia M.;
Marselli, Lorella;
Marchetti, Piero;
Roivainen, Merja;
Eizirik, Decio L.;
Op de beeck, Anne

Publication type:

Article

Genetic regulation of RNA splicing in human pancreatic islets.

Published in:

Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02757-0

By:

Atla, Goutham;
Bonàs-Guarch, Silvia;
Cuenca-Ardura, Mirabai;
Beucher, Anthony;
Crouch, Daniel J. M.;
Garcia-Hurtado, Javier;
Moran, Ignasi;
the T2DSystems Consortium;
Cnop, Miriam;
Eliasson, Lena;
Esguerra, Jonathan Lou S.;
Eizirik, Décio L.;
Groop, Leif;
Jensen, Thomas S.;
Hansen, Torben;
Marchetti, Piero;
Mercader, Josep M.;
Mulder, Hindrik;
Stabile-Barnett, Chris R.;
Thirion, Christian

Publication type:

Article

Gluco-Incretins Regulate Beta-Cell Glucose Competence by Epigenetic Silencing of Fxyd3 Expression.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0103277

By:

Vallois, David;
Niederhäuser, Guy;
Ibberson, Mark;
Nagaray, Vini;
Marselli, Lorella;
Marchetti, Piero;
Chatton, Jean-Yves;
Thorens, Bernard

Publication type:

Article

Automated Assessment of β-Cell Area and Density per Islet and Patient Using TMEM27 and BACE2 Immunofluorescence Staining in Human Pancreatic β-Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098932

By:

Rechsteiner, Markus P.;
Floros, Xenofon;
Boehm, Bernhard O.;
Marselli, Lorella;
Marchetti, Piero;
Stoffel, Markus;
Moch, Holger;
Spinas, Giatgen A.

Publication type:

Article

Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036188

By:

Martino, Luisa;
Masini, Matilde;
Novelli, Michela;
Beffy, Pascale;
Bugliani, Marco;
Marselli, Lorella;
Masiello, Pellegrino;
Marchetti, Piero;
De Tata, Vincenzo

Publication type:

Article

The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031062

By:

Moore, Fabrice;
Santin, Izortze;
Nogueira, Tatiane C.;
Gurzov, Esteban N.;
Marselli, Lorella;
Marchetti, Piero;
Eizirik, Decio L.

Publication type:

Article

Altered Insulin Receptor Signalling and β-Cell Cycle Dynamics in Type 2 Diabetes Mellitus.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0028050

By:

Folli, Franco;
Okada, Terumasa;
Perego, Carla;
Gunton, Jenny;
Chong Wee Liew;
Akiyama, Masaru;
D'Amico, Anna;
La Rosa, Stefano;
Placidi, Claudia;
Lupi, Roberto;
Marchetti, Piero;
Sesti, Giorgio;
Hellerstein, Marc;
Perego, Lucia;
Kulkarni, Rohit N.

Publication type:

Article

ENPP1 Affects Insulin Action and Secretion: Evidences from In Vitro Studies.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019462

By:

Di Paola, Rosa;
Caporarello, Nunzia;
Marucci, Antonella;
Dimatteo, Claudia;
Iadicicco, Claudia;
Del Guerra, Silvia;
Prudente, Sabrina;
Sudano, Dora;
Miele, Claudia;
Parrino, Cristina;
Piro, Salvatore;
Beguinot, Francesco;
Marchetti, Piero;
Trischitta, Vincenzo;
Frittitta, Lucia

Publication type:

Article

Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes.

Published in:

PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011499

By:

Marselli, Lorella;
Thorne, Jeffrey;
Dahiya, Sonika;
Sgroi, Dennis C.;
Sharma, Arun;
Bonner-Weir, Susan;
Marchetti, Piero;
Weir, Gordon C.

Publication type:

Article

Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors.

Published in:

PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0011053

By:

Kirkpatrick, Clare L.;
Marchetti, Piero;
Purrello, Francesco;
Piro, Salvatore;
Bugliani, Marco;
Bosco, Domenico;
de Koning, Eelco J. P.;
Engelse, Marten A.;
Kerr-Conte, Julie;
Pattou, François;
Wollheim, Claes B.

Publication type:

Article

MiR-184 expression is regulated by AMPK in pancreatic islets.

Published in:

FASEB Journal, 2018, v. 32, n. 5, p. 2587, doi. 10.1096/fj.201701100R

By:

Martinez-Sanchez, Aida;
Nguyen-Tu, Marie-Sophie;
Cebola, Ines;
Yavari, Arash;
Marchetti, Piero;
Piemonti, Lorenzo;
de Koning, Eelco;
Shapiro, A. M. James;
Johnson, Paul;
Kei Sakamoto;
Smith, David M.;
Leclerc, Isabelle;
Ashrafian, Houman;
Ferrer, Jorge;
Rutter, Guy A.

Publication type:

Article

Exercise training protects human and rodent β cells against endoplasmic reticulum stress and apoptosis.

Published in:

FASEB Journal, 2018, v. 32, n. 3, p. 1524, doi. 10.1096/fj.201700710R

By:

Paula, Flavia M. M.;
Leite, Nayara C.;
Borck, Patricia C.;
Freitas-Dias, Ricardo;
Cnop, Miriam;
Chacon-Mikahil, Mara P. T.;
Cavaglieri, Claudia R.;
Marchetti, Piero;
Boschero, Antonio C.;
Zoppi, Claudio C.;
Eizirik, Decio L.

Publication type:

Article

A2A adenosine receptors control pancreatic dysfunction in high-fat-diet-induced obesity.

Published in:

FASEB Journal, 2017, v. 31, n. 11, p. 4985, doi. 10.1096/fj.201700398R

By:

Csóka, Balázs;
Törő, Gábor;
Vindeirinho, Joana;
Varga, Zoltán V.;
Koscsó, Balázs;
Németh, Zoltán H.;
Kókai, Endre;
Antonioli, Luca;
Suleiman, Mara;
Marchetti, Piero;
Cseri, Karolina;
Deák, Ádám;
Virág, László;
Pacher, Pál;
Bai, Péter;
Haskó, György

Publication type:

Article

Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic β-cells.

Published in:

FASEB Journal, 2004, v. 18, n. 9, p. 959, doi. 10.1096/fj.03-0725fje

By:

D'Alessandris, Cristina;
Andreozzi, Francesco;
Federici, Massimo;
Cardellini, Marina;
Brunetti, Antonio;
Ranall, Marco;
Del Guerra, Silvia;
Lauro, Davide;
Del Prato, Stefano;
Marchetti, Piero;
Lauro, Renato;
Sesti, Giorgio

Publication type:

Article

Functional and molecular defects of pancreatic islets in human type 2 diabetes.

Published in:

2005

By:

Del Guerra, Silvia;
Lupi, Roberto;
Marselli, Lorella;
Masini, Matilde;
Bugliani, Marco;
Sbrana, Simone;
Torri, Scilla;
Pollera, Maria;
Boggi, Ugo;
Mosca, Franco;
Del Prato, Stefano;
Marchetti, Piero

Publication type:

journal article

A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects.

Published in:

2003

By:

Sesti, Giorgio;
Cardellini, Marina;
Marini, Maria Adelaide;
Frontoni, Simona;
D'Adamo, Monica;
Del Guerra, Silvia;
Lauro, Davide;
De Nicolais, Pierluigi;
Sbraccia, Paolo;
Del Prato, Stefano;
Gambardella, Sergio;
Federici, Massimo;
Marchetti, Piero;
Lauro, Renato

Publication type:

journal article

Prolonged in vitro exposure to autoantibodies against CD38 impairs the function and survival of human pancreatic islets.

Published in:

2002

By:

Marchetti, Piero;
Antonelli, Alessandro;
Lupi, Roberto;
Marselli, Lorella;
Fallahi, Poupak;
Nesti, Claudia;
Baj, Germano;
Ferrannini, Ele

Publication type:

journal article

Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism.

Published in:

2002

By:

Marchetti, Piero;
Lupi, Roberto;
Federici, Massimo;
Marselli, Lorella;
Masini, Matilde;
Boggi, Ugo;
Del Guerra, Silvia;
Patanè, Giovanni;
Piro, Salvatore;
Anello, Marcello;
Bergamini, Ettore;
Purrello, Francesco;
Lauro, Renato;
Mosca, Franco;
Sesti, Giorgio;
Del Prato, Stefano;
Patanè, Giovanni

Publication type:

journal article

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

Published in:

2002

By:

Lupi, Roberto;
Dotta, Francesco;
Marselli, Lorella;
Guerra, Silvia Del;
Masini, Matilde;
Santangelo, Carmela;
Patané, Giovanni;
Boggi, Ugo;
Piro, Salvatore;
Anello, Marcello;
Bergamini, Ettore;
Mosca, Franco;
Mario, Umberto Di;
Prato, Stefano Del;
Marchetti, Piero;
Del Guerra, Silvia;
Patané, Giovanni;
Di Mario, Umberto;
Del Prato, Stefano

Publication type:

journal article

Phasic insulin release and metabolic regulation in type 2 diabetes.

Published in:

2002

By:

Del Prato, Stefano;
Marchetti, Piers;
Bonadonna, Riecardo C.;
Marchetti, Piero;
Bonadonna, Riccardo C

Publication type:

journal article