Works by MALIK, Asrar B.

Results: 106

Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating β2 integrins.

Published in:

Nature Immunology, 2008, v. 9, n. 8, p. 880, doi. 10.1038/ni.1628

By:

Xu, Jingsong;
Gao, Xiao-Pei;
Ramchandran, Ramaswamy;
Zhao, You-Yang;
Vogel, Stephen M;
Malik, Asrar B

Publication type:

Article

Endosomal trafficking of two-pore K+ efflux channel TWIK2 to plasmalemma mediates NLRP3 inflammasome activation and inflammatory injury.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.83842

By:

Long Shuang Huang;
Anas, Mohammad;
Jingsong Xu;
Bisheng Zhou;
Toth, Peter T.;
Krishnan, Yamuna;
Di, Anke;
Malik, Asrar B.

Publication type:

Article

Compensatory lymphangiogenesis is required for edema resolution in zebrafish.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-92970-1

By:

Olayinka, Olamide;
Ryu, Hannah;
Wang, Xiaowei;
Malik, Asrar B.;
Jung, Hyun Min

Publication type:

Article

Ca2+ Signaling, TRP Channels, and Endothelial Permeability.

Published in:

Microcirculation, 2006, v. 13, n. 8, p. 693, doi. 10.1080/10739680600930347

By:

TIRUPPATHI, CHINNASWAMY;
AHMMED, GIAS U.;
VOGEL, STEPHEN M.;
MALIK, ASRAR B.

Publication type:

Article

Physiological Modeling of the Vascularized Human Lung Organoid.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 72, n. 4, p. 354, doi. 10.1165/rcmb.2024-0413MA

By:

Qadir, Abdul S.;
Das, Sukanta;
Nedunchezian, Swathi;
Masuhara, Kaori;
Desai, Tushar J.;
Rehman, Jalees;
Kadur Murthy, Preetish;
Tsukasaki, Yoshikazu;
Shao, Lijian;
Malik, Asrar B.

Publication type:

Article

CD38-mediated Inhibition of Bruton's Tyrosine Kinase in Macrophages Prevents Endotoxemic Lung Injury.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 2, p. 183, doi. 10.1165/rcmb.2021-0272OC

By:

Farahany, Joseph;
Yoshikazu Tsukasaki;
Mukhopadhyay, Amitabha;
Mittal, Manish;
Nepal, Saroj;
Tiruppathi, Chinnaswamy;
Malik, Asrar B.

Publication type:

Article

Quantitative Pulmonary Neutrophil Dynamics using Computer-Vision Stabilized Intravital Imaging.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 1, p. E1, doi. 10.1165/rcmb.2021-0318ma

By:

Yoshikazu Tsukasaki;
Toth, Peter T.;
Davoodi, Esmaeil;
Rehman, Jalees;
Malik, Asrar B.

Publication type:

Article

Quantitative Pulmonary Neutrophil Dynamics Using Computer-Vision Stabilized Intravital Imaging.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 1, p. 12, doi. 10.1165/rcmb.2021-0318MA

By:

Yoshikazu Tsukasaki;
Toth, Peter T.;
Davoodi-Bojd, Esmaeil;
Rehman, Jalees;
Malik, Asrar B.

Publication type:

Article

PV1 in Caveolae Controls Lung Endothelial Permeability.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2020, v. 63, n. 4, p. 531, doi. 10.1165/rcmb.2020-0102OC

By:

Jones, Joshua H.;
Friedrich, Emily;
Zhigang Hong;
Minshall, Richard D.;
Malik, Asrar B.

Publication type:

Article

Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2020, v. 62, n. 2, p. 168, doi. 10.1165/rcmb.2019-0024OC

By:

Ming Zhong;
Wei Wu;
Hojin Kang;
Zhigang Hong;
Shiqin Xiong;
Xiaopei Gao;
Rehman, Jalees;
Komarova, Yulia A.;
Malik, Asrar B.

Publication type:

Article

Activation of Type II Cells into Regenerative Stem Cell Antigen-1+ Cells during Alveolar Repair.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2015, v. 53, n. 1, p. 113, doi. 10.1165/rcmb.2013-0497OC

By:

Yuru Liu;
Kumar, Varsha Suresh;
Wei Zhang;
Rehman, Jalees;
Malik, Asrar B.

Publication type:

Article

Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function.

Published in:

Histochemistry & Cell Biology, 2002, v. 117, n. 2, p. 105, doi. 10.1007/s00418-001-0367-x

By:

Minshall, Richard D.;
Tiruppathi, Chinnaswamy;
Vogel, Stephen M.;
Malik, Asrar B.

Publication type:

Article

KIF13B-mediated VEGFR2 trafficking is essential for vascular leakage and metastasis in vivo.

Published in:

Life Science Alliance, 2022, v. 5, n. 1, p. 1, doi. 10.26508/lsa.202101170

By:

Waters, Stephen B.;
Dominguez, Joseph R.;
Hyun-Dong Cho;
Sarich, Nicolene A.;
Malik, Asrar B.;
Yamada, Kaori H.

Publication type:

Article

Gasdermin D pores are dynamically regulated by local phosphoinositide circuitry.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27692-9

By:

Santa Cruz Garcia, Ana Beatriz;
Schnur, Kevin P.;
Malik, Asrar B.;
Mo, Gary C. H.

Publication type:

Article

Integrin α6β1 Expressed in ESCs Instructs the Differentiation to Endothelial Cells.

Published in:

Stem Cells, 2015, v. 33, n. 6, p. 1719, doi. 10.1002/stem.1974

By:

Toth, Peter T.;
Toya, Sophie P.;
Rehman, Jalees;
Wary, Kishore K.;
Mittal, Manish;
Li, Fei;
Park, Changwon;
Malik, Asrar B.

Publication type:

Article

IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury.

Published in:

2020

By:

Shiqin Xiong;
Zhigang Hong;
Long Shuang Huang;
Yoshikazu Tsukasaki;
Saroj Nepal;
Anke Di;
Ming Zhong;
Wei Wu;
Zhiming Ye;
Xiaopei Gao;
Rao, Gadiparthi N.;
Mehta, Dolly;
Rehman, Jalees;
Malik, Asrar B.;
Xiong, Shiqin;
Hong, Zhigang;
Huang, Long Shuang;
Tsukasaki, Yoshikazu;
Nepal, Saroj;
Di, Anke

Publication type:

journal article

Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.

Published in:

2017

By:

Kwong Tai Cheng;
Shiqin Xiong;
Zhiming Ye;
Zhigang Hong;
Di, Anke;
Tsang, Kit Man;
Xiaopei Gao;
Shejuan An;
Mittal, Manish;
Vogel, Stephen M.;
Miao, Edward A.;
Rehman, Jalees;
Malik, Asrar B.;
Cheng, Kwong Tai;
Xiong, Shiqin;
Ye, Zhiming;
Hong, Zhigang;
Gao, Xiaopei;
An, Shejuan

Publication type:

journal article

HIF2α signaling inhibits adherens junctional disruption in acute lung injury.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 652, doi. 10.1172/JCI77701

By:

Haixia Gong;
Rehman, Jalees;
Haiyang Tang;
Wary, Kishore;
Mittal, Manish;
Chatturvedi, Pallavi;
Youyang Zhao;
Komorova, Yulia A.;
Vogel, Stephen M.;
Malik, Asrar B.

Publication type:

Article

Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration.

Published in:

2009

By:

You-Yang Zhao;
Zhao, Yidan D.;
Mirza, Muhammad K.;
Huang, Julia H.;
Potula, Hari-Hara S. K.;
Vogel, Steven M.;
Brovkovych, Viktor;
Yuan, Jason X.-J.;
Wharton, John;
Malik, Asrar B.;
Zhao, You-Yang

Publication type:

journal article

Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury.

Published in:

2006

By:

Zhao, You-Yang;
Gao, Xiao-Pei;
Zhao, Yidan D;
Mirza, Muhammad K;
Frey, Randall S;
Kalinichenko, Vladimir V;
Wang, I-Ching;
Costa, Robert H;
Malik, Asrar B

Publication type:

journal article

Endothelial cell--restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 9, p. 2333, doi. 10.1172/JCI27154

By:

You-Yang Zhao;
Xiao-Pei Gao;
Zhao, Yidan D.;
Mirza, Muhammad K.;
Frey, Randall S.;
Kalinichenko, Vladimir V.;
I-Ching Wang;
Costa, Robert H.;
Malik, Asrar B.

Publication type:

Article

Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box m1 transcription factor.

Published in:

Developmental Dynamics, 2007, v. 236, n. 4, p. 1000, doi. 10.1002/dvdy.21113

By:

Sneha Ramakrishna;
Il‐Man Kim;
Vladimir Petrovic;
Dmitriy Malin;
I‐Ching Wang;
Tanya V. Kalin;
Lucille Meliton;
You‐Yang Zhao;
Timothy Ackerson;
Yimin Qin;
Asrar B. Malik;
Robert H. Costa;
Vladimir V. Kalinichenko

Publication type:

Article

Mechanisms of Lung Vascular Injury and Edema Induced by Pulmonary Microembolism.

Published in:

Medical Principles & Practice, 1990, v. 2, n. 1, p. 1, doi. 10.1159/000157326

By:

Malik, Asrar B.

Publication type:

Article

Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s.

Published in:

Journal of Cellular & Molecular Medicine, 2011, v. 15, n. 11, p. 2364, doi. 10.1111/j.1582-4934.2010.01226.x

By:

Knezevic, Ivana;
Predescu, Dan;
Bardita, Cristina;
Wang, Minhua;
Sharma, Tiffany;
Keith, Barbara;
Neamu, Radu;
Malik, Asrar B.;
Predescu, Sanda

Publication type:

Article

Thrombin-Induced Alterations in Endothelial Permeabilitya.

Published in:

Annals of the New York Academy of Sciences, 1986, v. 485, n. 1, p. 293, doi. 10.1111/j.1749-6632.1986.tb34591.x

By:

MALIK, ASRAR B.;
LO, SIU K.;
BIZIOS, RENA

Publication type:

Article

METABOLIC FACTORS AS MEDIATORS OF PULMONARY VASCULAR INJURY*.

Published in:

Annals of the New York Academy of Sciences, 1982, v. 384, n. 1, p. 344, doi. 10.1111/j.1749-6632.1982.tb21383.x

By:

Barie, Philip S.;
Malik, Asrar B.

Publication type:

Article

PREFACE.

Published in:

Annals of the New York Academy of Sciences, 1982, v. 384, n. 1, p. ix, doi. 10.1111/j.1749-6632.1982.tb21355.x

By:

Malik, Asrar B.;
Staub, Norman C.

Publication type:

Article

MECHANISMS OF LUNG VASCULAR INJURY AFTER INTRAVASCULAR COAGULATION*.

Published in:

Annals of the New York Academy of Sciences, 1982, v. 384, n. 1, p. 213, doi. 10.1111/j.1749-6632.1982.tb21374.x

By:

Malik, Asrar B.;
Johnson, Arnold;
Tahamont, Maria V.

Publication type:

Article

MECHANISMS OF NEUROGENIC PULMONARY EDEMA*.

Published in:

Annals of the New York Academy of Sciences, 1982, v. 384, n. 1, p. 169, doi. 10.1111/j.1749-6632.1982.tb21371.x

By:

Minnear, Fred L.;
Malik, Asrar B.

Publication type:

Article

Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function.

Published in:

Journal of Physiology, 2002, v. 539, n. 3, p. 779, doi. 10.1113/jphysiol.2001.013289

By:

Mehta, Dolly;
Tiruppathi, Chinnaswamy;
Sandoval, Raudal;
Minshall, Richard D.;
Holinstat, Michael;
Malik, Asrar B.

Publication type:

Article

Ca2+ signalling and PKCα activate increased endothelial permeability by disassembly of VE-cadherin junctions.

Published in:

Journal of Physiology, 2001, v. 533, n. 2, p. 433, doi. 10.1111/j.1469-7793.2001.0433a.x

By:

Sandoval, Raudel;
Malik, Asrar B.;
Minshall, Richard D.;
Kouklis, Panos;
Ellis, Chad A.;
Tiruppathi, Chinnaswamy

Publication type:

Article

Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung.

Published in:

Journal of Physiology, 2001, v. 533, n. 2, p. 547, doi. 10.1111/j.1469-7793.2001.0547a.x

By:

John, Theresa A.;
Vogel, Stephen M.;
Minshall, Richard D.;
Ridge, Karen;
Tiruppathi, Chinnaswamy;
Malik, Asrar B.

Publication type:

Article

A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks.

Published in:

BMC Bioinformatics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12859-018-2190-6

By:

Jambusaria, Ankit;
Klomp, Jeff;
Hong, Zhigang;
Rafii, Shahin;
Dai, Yang;
Malik, Asrar B.;
Rehman, Jalees

Publication type:

Article

Inhibition of endothelial cell proliferation and bFGF-induced phenotypic modulation by nitric oxide.

Published in:

Journal of Cellular Biochemistry, 1996, v. 63, n. 2, p. 125, doi. 10.1002/(SICI)1097-4644(19961101)63:2<125::AID-JCB1>3.0.CO;2-#

By:

RayChaudhury, Amlan;
Frischer, Henri;
Malik, Asrar B.

Publication type:

Article

Adrenergic Mechanisms and the Pulmonary Vascular Response to Respiratory Acidosis.

Published in:

Respiration, 1976, v. 33, n. 3, p. 179, doi. 10.1159/000193732

By:

Malik, Asrar B.;
Newmark, Joseph M.

Publication type:

Article

Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42225-2

By:

Tiruppathi, Chinnaswamy;
Wang, Dong-Mei;
Ansari, Mohammad Owais;
Bano, Shabana;
Tsukasaki, Yoshikazu;
Mukhopadhyay, Amitabha;
Joshi, Jagdish C.;
Loch, Christian;
Niessen, Hans W. M.;
Malik, Asrar B.

Publication type:

Article

An ACE2 decoy can be administered by inhalation and potently targets omicron variants of SARS‐CoV‐2.

Published in:

EMBO Molecular Medicine, 2022, v. 14, n. 11, p. 1, doi. 10.15252/emmm.202216109

By:

Zhang, Lianghui;
Narayanan, Krishna K;
Cooper, Laura;
Chan, Kui K;
Skeeters, Savanna S;
Devlin, Christine A;
Aguhob, Aaron;
Shirley, Kristie;
Rong, Lijun;
Rehman, Jalees;
Malik, Asrar B;
Procko, Erik

Publication type:

Article

Prevention of vascular inflammation by nanoparticle targeting of adherent neutrophils.

Published in:

Nature Nanotechnology, 2014, v. 9, n. 3, p. 204, doi. 10.1038/nnano.2014.17

By:

Wang, Zhenjia;
Li, Jing;
Cho, Jaehyung;
Malik, Asrar B.

Publication type:

Article

Role of Adrenergic Mechanisms in the Development of Cardiac Hypertrophy1.

Published in:

Proceedings of the Society for Experimental Biology & Medicine, 1975, v. 150, n. 3, p. 796, doi. 10.3181/00379727-150-39127

By:

Malik, Asrar B.;
Geha, Alexander S.

Publication type:

Article

Erratum: Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors.

Published in:

2003

By:

Fan, Jie;
Malik, Asrar B.

Publication type:

Erratum

Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors.

Published in:

Nature Medicine, 2003, v. 9, n. 3, p. 315, doi. 10.1038/nm832

By:

Fan, Jie;
Malik, Asrar B.

Publication type:

Article

Endothelial Barrier Function.

Published in:

Journal of Investigative Dermatology, 1989, v. 93, p. 62S, doi. 10.1038/jid.1989.11

By:

Malik, Asrar B.;
Lynch, Joseph J.;
Cooper, Jeffrey A.

Publication type:

Article

Lipid Phosphate Phosphatase 3 Stabilization of β-Catenin Induces Endothelial Cell Migration and Formation of Branching Point Structures.

Published in:

Molecular & Cellular Biology, 2010, v. 30, n. 7, p. 3, doi. 10.1128/MCB.00038-09

By:

Humtsoe, Joseph O.;
Mingyao Liu;
Malik, Asrar B.;
Wary, Kishore K.

Publication type:

Article

GDI-1 Phosphorylation Switch at Serine 96 Induces RhoA Activation and Increased Endothelial Permeability.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 18, p. 6, doi. 10.1128/MCB.00523-07

By:

Knezevic, Nebojsa;
Roy, Arun;
Timblin, Barbara;
Konstantoulaki, Maria;
Sharma, Tiffany;
Malik, Asrar B.;
Mehta, Dolly

Publication type:

Article

Functional role of TRPC channels in the regulation of endothelial permeability.

Published in:

Pflügers Archiv: European Journal of Physiology, 2005, v. 451, n. 1, p. 131, doi. 10.1007/s00424-005-1461-z

By:

Ahmmed, Gias U.;
Malik, Asrar B.

Publication type:

Article

The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation.

Published in:

Nature Immunology, 2014, v. 15, n. 3, p. 239, doi. 10.1038/ni.2823

By:

Tiruppathi, Chinnaswamy;
Soni, Dheeraj;
Wang, Dong-Mei;
Xue, Jiaping;
Singh, Vandana;
Thippegowda, Prabhakar B;
Cheppudira, Bopaiah P;
Mishra, Rakesh K;
DebRoy, Auditi;
Qian, Zhijian;
Bachmaier, Kurt;
Zhao, You-Yang;
Christman, John W;
Vogel, Stephen M;
Ma, Averil;
Malik, Asrar B

Publication type:

Article

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation.

Published in:

Nature Immunology, 2012, v. 13, n. 6, p. 621, doi. 10.1038/ni0612-621e

By:

Di, Anke;
Gao, Xiao-Pei;
Qian, Feng;
Kawamura, Takeshi;
Han, Jin;
Hecquet, Claudie;
Ye, Richard D;
Vogel, Stephen M;
Malik, Asrar B.

Publication type:

Article

Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases.

Published in:

Nature Immunology, 2012, v. 13, n. 5, p. 457, doi. 10.1038/ni.2258

By:

Liu, Xiaowen;
Ma, Bo;
Malik, Asrar B;
Tang, Haiyang;
Yang, Tao;
Sun, Bo;
Wang, Gang;
Minshall, Richard D;
Li, Yan;
Zhao, Yong;
Ye, Richard D;
Xu, Jingsong

Publication type:

Article

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation.

Published in:

Nature Immunology, 2012, v. 13, n. 1, p. 29, doi. 10.1038/ni.2171

By:

Di, Anke;
Gao, Xiao-Pei;
Qian, Feng;
Kawamura, Takeshi;
Han, Jin;
Hecquet, Claudie;
Ye, Richard D;
Vogel, Stephen M;
Malik, Asrar B

Publication type:

Article

Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis.

Published in:

Journal of Cell Biology, 2020, v. 219, n. 2, p. 1, doi. 10.1083/jcb.201903023

By:

Collins, Kerrie B.;
Hojin Kang;
Matsche, Jacob;
Klomp, Jennifer E.;
Rehman, Jalees;
Malik, Asrar B.;
Karginov, Andrei V.

Publication type:

Article