Works by MADDUX, BETTY A.

Results: 34

Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.

Published in:

BMC Endocrine Disorders, 2012, v. 12, n. 1, p. 31, doi. 10.1186/1472-6823-12-31

By:

Masharani, Umesh;
Gjerde, Christine;
McCoy, Shelley;
Maddux, Betty A.;
Hessler, Danielle;
Goldfine, Ira D.;
Youngren, Jack F.

Publication type:

Article

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.

Published in:

Nature Genetics, 2005, v. 37, n. 8, p. 863, doi. 10.1038/ng1604

By:

Meyre, David;
Bouatia-Naji, Nabila;
Tounian, Agnès;
Samson, Chantal;
Lecoeur, Cécile;
Vatin, Vincent;
Ghoussaini, Maya;
Wachter, Christophe;
Hercberg, Serge;
Charpentier, Guillaume;
Patsch, Wolfgang;
Pattou, François;
Charles, Marie-Aline;
Tounian, Patrick;
Clément, Karine;
Jouret, Béatrice;
Weill, Jacques;
Maddux, Betty A.;
Goldfine, Ira D.;
Walley, Andrew

Publication type:

Article

XOMA 052, an anti-IL-1β monoclonal antibody, prevents IL-1β-mediated insulin resistance in 3T3-L1 adipocytes.

Published in:

Obesity (19307381), 2013, v. 21, p. 306, doi. 10.1002/oby.20004

By:

Handa, Masahisa;
Vanegas, Sandra;
Maddux, Betty A.;
Mendoza, Nerissa;
Zhu, Shirley;
Goldfine, Ira D.;
Mirza, Amer M.

Publication type:

Article

XOMA 052, an anti-IL-1β monoclonal antibody, prevents IL-1β-mediated insulin resistance in 3T3-L1 adipocytes.

Published in:

2013

By:

Handa, Masahisa;
Vanegas, Sandra;
Maddux, Betty A;
Mendoza, Nerissa;
Zhu, Shirley;
Goldfine, Ira D;
Mirza, Amer M

Publication type:

journal article

XOMA 052, an anti-IL-1β monoclonal antibody, prevents IL-1β-mediated insulin resistance in 3T3-L1 adipocytes.

Published in:

Obesity (19307381), 2013, v. 21, n. 2, p. 306, doi. 10.1002/oby.20004

By:

Handa, Masahisa;
Vanegas, Sandra;
Maddux, Betty A.;
Mendoza, Nerissa;
Zhu, Shirley;
Goldfine, Ira D.;
Mirza, Amer M.

Publication type:

Article

IGF-Binding Protein-1 Levels Are Related to Insulin-Mediated Glucose Disposal and Are a Potential Serum Marker of Insulin Resistance.

Published in:

2006

By:

Maddux, Betty A.;
Chan, Adelene;
Mandarino, Lawrence J.;
Goldfine, Ira D.

Publication type:

Case Study

A Soluble PC-1 Circulates in Human Plasma: Relationship with Insulin Resistance and Associated Abnormalities.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 10, p. 3620, doi. 10.1210/jcem.84.10.6050

By:

FRITTITTA, LUCIA;
CAMASTRA, STEFANIA;
BARATTA, ROBERTO;
COSTANZO, BENEDETTA V.;
D’ADAMO, MONICA;
GRACI, SALVATORE;
SPAMPINATO, DANIELA;
MADDUX, BETTY A.;
VIGNERI, RICCARDO;
FERRANNINI, ELEUTERIO;
TRISCHITTA, VINCENZO

Publication type:

Article

Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells.

Published in:

Prostate, 2008, v. 68, n. 11, p. 1232, doi. 10.1002/pros.20789

By:

Ryan, Charles J.;
Zavodovskaya, Marianna;
Youngren, Jack F.;
Campbell, Michael;
Diamond, Marc;
Jones, Jeremy;
Shiry, Laura;
Allan, Geoffrey;
Maddux, Betty A.;
Goldfine, Ira D.

Publication type:

Article

Nordihydroguaiaretic Acid (NDGA) Inhibits the IGF-1 and c-erbB2/HER2/neu Receptors and Suppresses Growth in Breast Cancer Cells.

Published in:

Breast Cancer Research & Treatment, 2005, v. 94, n. 1, p. 37, doi. 10.1007/s10549-005-6939-z

By:

Jack Youngren;
Karissa Gable;
Cristina Penaranda;
Betty Maddux;
Marianna Zavodovskaya;
Margaret Lobo;
Michael Campbell;
John Kerner;
Ira Goldfine

Publication type:

Article

Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells.

Published in:

Journal of Cellular Biochemistry, 2008, v. 103, n. 2, p. 624, doi. 10.1002/jcb.21435

By:

Zavodovskaya, Marianna;
Campbell, Michael J.;
Maddux, Betty A.;
Shiry, Laura;
Allan, Geoffrey;
Hodges, Leslie;
Kushner, Peter;
Kerner, John A.;
Youngren, Jack F.;
Goldfine, Ira D.

Publication type:

Article

Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.

Published in:

Journal of Cellular Biochemistry, 2007, v. 102, n. 6, p. 1529, doi. 10.1002/jcb.21373

By:

Meyer, Gary E.;
Chesler, Louis;
Liu, Dandan;
Gable, Karissa;
Maddux, Betty A.;
Goldenberg, David D.;
Youngren, Jack F.;
Goldfine, Ira D.;
Weiss, William A.;
Matthay, Katherine K.;
Rosenthal, Stephen M.

Publication type:

Article

Overexpression of membrane glycoprotein PC-1 can influence insulin action at a post-receptor site.

Published in:

Journal of Cellular Biochemistry, 1998, v. 68, n. 3, p. 366, doi. 10.1002/(SICI)1097-4644(19980301)68:3<366::AID-JCB7>3.0.CO;2-S

By:

Kumakura, Shinobu;
Maddux, Betty A.;
Sung, Chin K.

Publication type:

Article

Effects of Testosterone and 5β-Androstanes on in Vitro Erythroid Colony Formation in Mouse Bone Marrow<sup>1</sup>.

Published in:

Proceedings of the Society for Experimental Biology & Medicine, 1981, v. 167, n. 1, p. 51, doi. 10.3181/00379727-167-41124

By:

Beckman, Barbara;
Maddux, Betty;
Segaloff, Albert;
Fisher, James W.

Publication type:

Article

Membrane glycoprotein in PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus.

Published in:

Nature, 1995, v. 373, n. 6513, p. 448, doi. 10.1038/373448a0

By:

Maddux, Betty A.;
Sbraccia, Paolo

Publication type:

Article

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control.

Published in:

Diabetes, 2012, v. 61, n. 5, p. 1263, doi. 10.2337/db11-1578

By:

Bhaskar, Vinay;
Goldfine, Ira D.;
Bedinger, Daniel H.;
Lau, Angela;
Kuan, Hua F.;
Gross, Lisa M.;
Handa, Masahisa;
Maddux, Betty A.;
Watson, Susan R.;
Zhu, Shirley;
Narasimha, Ajay J.;
Levy, Raphael;
Webster, Lynn;
Wijesuriya, Sujeewa D.;
Naichi Liu;
Xiaorong Wu;
Chemla-Vogel, David;
Tran, Catarina;
Lee, Steve R.;
Wong, Steve

Publication type:

Article

Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.

Published in:

2005

By:

Dong, Hengjiang;
Maddux, Betty A.;
Altomonte, Jennifer;
Meseck, Marcia;
Accili, Domenico;
Terkeltaub, Robert;
Johnson, Kristen;
Youngren, Jack F.;
Goldfine, Ira D.

Publication type:

journal article

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

Published in:

2003

By:

Evans, Joseph L;
Goldfine, Ira D;
Maddux, Betty A;
Grodsky, Gerold M

Publication type:

journal article

Perspectives in Diabetes/ Are Oxidative Stress--Activated Signaling Pathways Mediators of Insulin Resistance and Β-Cell Dysfunction?

Published in:

Diabetes, 2003, v. 52, n. 1, p. 1, doi. 10.2337/diabetes.52.1.1

By:

Evans, Joseph L.;
Goldfine, Ira D.;
Maddux, Betty A.;
Grodsky, Gerold M.

Publication type:

Article

Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells.

Published in:

2001

By:

Li, Ming;
Youngren, Jack F.;
Manchem, Vara Prasad;
Kozlowski, Michael;
Zhang, Bei B.;
Maddux, Betty A.;
Goldfine, Ira D.;
Li, M;
Youngren, J F;
Manchem, V P;
Kozlowski, M;
Zhang, B B;
Maddux, B A;
Goldfine, I D

Publication type:

journal article

Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by mircomolar concentrations of alpha-lipoic acid.

Published in:

2001

By:

Maddux, Betty A.;
See, Wendy;
Lawrence, Jr., John C.;
Goldflne, Amy L.;
Goldflne, Ira D.;
Evans, Joseph L.;
Maddux, B A;
See, W;
Lawrence, J C Jr;
Goldfine, A L;
Goldfine, I D;
Evans, J L

Publication type:

journal article

Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit.

Published in:

2000

By:

Maddux, Betty A.;
Goldfine, Ira D.;
Maddux, B A;
Goldfine, I D

Publication type:

journal article

Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity.

Published in:

Diabetes, 1996, v. 45, n. 10, p. 1324, doi. 10.2337/diab.45.10.1324

By:

Youngren, Jack;
Maddux, Betty;
Sasson, Shlomo;
Sbraccia, Paolo;
Tapscott, Edward;
Swanson, Melvin;
Dohm, G. Lynis;
Goldfine, Ira

Publication type:

Article

Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108693

By:

Catalano, Karyn J.;
Maddux, Betty A.;
Szary, Jaroslaw;
Youngren, Jack F.;
Goldfine, Ira D.;
Schaufele, Fred

Publication type:

Article

Improved Glucose Metabolism In Vitro and In Vivo by an Allosteric Monoclonal Antibody That Increases Insulin Receptor Binding Affinity.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088684

By:

Corbin, John A.;
Bhaskar, Vinay;
Goldfine, Ira D.;
Bedinger, Daniel H.;
Lau, Angela;
Michelson, Kristen;
Gross, Lisa M.;
Maddux, Betty A.;
Kuan, Hua F.;
Tran, Catarina;
Lao, Llewelyn;
Handa, Masahisa;
Watson, Susan R.;
Narasimha, Ajay J.;
Zhu, Shirley;
Levy, Raphael;
Webster, Lynn;
Wijesuriya, Sujeewa D.;
Liu, Naichi;
Wu, Xiaorong

Publication type:

Article

Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019878

By:

Masharani, Umesh B.;
Maddux, Betty A.;
Xiaojuan Li;
Sakkas, Giorgos K.;
Mulligan, Kathleen;
Schambelan, Morris;
Goldfine, Ira D.;
Youngren, Jack F.

Publication type:

Article

Role of PC-1 in The Etiology of Insulin Resistance.

Published in:

Annals of the New York Academy of Sciences, 1999, v. 892, n. 1, p. 204, doi. 10.1111/j.1749-6632.1999.tb07797.x

By:

GOLDFINE, IRA D.;
MADDUX, BETTY A.;
YOUNGREN, JACK F.;
TRISCHITTA, VINCENZO;
FRITTITTA, LUCIA

Publication type:

Article

Insulin-cholera toxin binding unit conjugate: A hybrid molecule with insulin biological activity and cholera toxin binding specificity.

Published in:

Journal of Cellular Physiology, 1983, v. 115, n. 2, p. 151, doi. 10.1002/jcp.1041150208

By:

Roth, Richard A.;
Maddux, Betty

Publication type:

Article

Inhibition of insulin receptor function by a human, allosteric monoclonal antibody.

Published in:

mAbs (1942-0862), 2014, v. 6, n. 1, p. 1, doi. 10.4161/mabs.26871

By:

Corbin, John A.;
Bhaskar, Vinay;
Goldfine, Ira D.;
Issafras, Hassan;
Bedinger, Daniel H.;
Lau, Angela;
Michelson, Kristen;
Gross, Lisa M.;
Maddux, Betty;
Hua F. Kuan;
Tran, Catarina;
Lao, Llewelyn;
Handa, Masahisa;
Watson, Susan R.;
Narasimha, Ajay J.;
Zhu, Shirley;
Levy, Raphael;
Webster, Lynn;
Wijesuriya, Sujeewa D.;
Naichi Liu

Publication type:

Article

Production of inhibitor of insulin-receptor tyrosine kinase in fibroblasts from patient with insulin resistance and NIDDM.

Published in:

1991

By:

Sbraccia, Paolo;
Goodman, Patricia A.;
Maddux, Betty A.;
Wong, K. Y.;
Chen, Y.-D. I.;
Reaven, Gerald M.;
Goldfine, Ira D.;
Sbraccia, P;
Goodman, P A;
Maddux, B A;
Chen, Y D;
Reaven, G M;
Goldfine, I D

Publication type:

journal article

Mechanisms of insulin-induced insulin-receptor downregulation. Decrease of receptor biosynthesis and mRNA levels.

Published in:

1989

By:

Okabayashi, Yoshinori;
Maddux, Betty A.;
McDonald, Alexander R.;
Logsdon, Craig D.;
Williams, John A.;
Goldfine, Ira D.;
Okabayashi, Y;
Maddux, B A;
McDonald, A R;
Logsdon, C D;
Williams, J A;
Goldfine, I D

Publication type:

journal article

Sequence and analysis of promoter region of human insulin-receptor gene.

Published in:

1988

By:

Mamula, Paul W.;
Kwok-Ying Wong;
Maddux, Betty A.;
Mcdonald, Alexander R.;
Goldfine, Ira D.;
Mamula, P W;
Wong, K Y;
Maddux, B A;
McDonald, A R;
Goldfine, I D

Publication type:

journal article

Regulation of insulin-receptor mRNA levels by glucocorticoids.

Published in:

1987

By:

McDonald, Alex R.;
Maddux, Betty A.;
Okabayashi, Y.;
Wong, K. Y.;
Hawley, D. M.;
Logsdon, Craig D.;
Goldfine, Ira D.;
McDonald, A R;
Maddux, B A;
Logsdon, C D;
Goldfine, I D

Publication type:

journal article

Biosynthesis and processing of the human insulin receptor.

Published in:

1986

By:

Forsayeth, John;
Maddux, Betty;
Goldfine, Ira D.;
Forsayeth, J;
Maddux, B;
Goldfine, I D

Publication type:

journal article

Tissue-specific antibodies against the fibroblast insulin receptor in a patient with lupus nephritis and hypoglycemia.

Published in:

1985

By:

De Pirro, Roberto;
Borboni, Patrizia;
Lauro, Renato;
Festa, Antonella;
Testa, Ivano;
De Martinis, Carlo;
Maddux, Betty A.;
Goldfine, Ira D.;
De Pirro, R;
Borboni, P;
Lauro, R;
Festa, A;
Testa, I;
De Martinis, C;
Maddux, B A;
Goldfine, I D

Publication type:

journal article