Works by Müller-Newen, Gerhard

Results: 40

Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA.

Published in:

Advanced Science, 2025, v. 12, n. 9, p. 1, doi. 10.1002/advs.202409729

By:

Lin, Cheng;
Kuzmanović, Adrian;
Wang, Nan;
Liao, Liangliang;
Ernst, Sabrina;
Penners, Christian;
Jans, Alexander;
Hammoor, Thomas;
Stach, Petra Bumnuri;
Peltzer, Mona;
Volkert, Ines;
Zechendorf, Elisabeth;
Hassan, Reham;
Myllys, Maiju;
Liedtke, Christian;
Herrmann, Andreas;
Chakraborty, Gurudas;
Trautwein, Christian;
Hengstler, Jan;
Müller‐Newen, Gerhard

Publication type:

Article

Assessing the Intracellular Integrity of Phosphine-Stabilized Ultrasmall Cytotoxic Gold Nanoparticles Enabled by Fluorescence Labeling.

Published in:

Advanced Healthcare Materials, 2016, v. 5, n. 24, p. 3118, doi. 10.1002/adhm.201600892

By:

Broda, Janine;
Küster, Andrea;
Westhues, Stefan;
Fahrenkamp, Dirk;
Vogg, Andreas T. J.;
Steitz, Julia;
Mottaghy, Felix M.;
Müller‐Newen, Gerhard;
Simon, Ulrich

Publication type:

Article

Cellular Uptake: Assessing the Intracellular Integrity of Phosphine-Stabilized Ultrasmall Cytotoxic Gold Nanoparticles Enabled by Fluorescence Labeling (Adv. Healthcare Mater. 24/2016).

Published in:

Advanced Healthcare Materials, 2016, v. 5, n. 24, p. 3088, doi. 10.1002/adhm.201670128

By:

Broda, Janine;
Küster, Andrea;
Westhues, Stefan;
Fahrenkamp, Dirk;
Vogg, Andreas T. J.;
Steitz, Julia;
Mottaghy, Felix M.;
Müller‐Newen, Gerhard;
Simon, Ulrich

Publication type:

Article

Retraction: Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies.

Published in:

2009

By:

Haug, Karsten;
Warnstedt, Maike;
Alekov, Alexi K;
Sander, Thomas;
Ramírez, Alfredo;
Poser, Barbara;
Maljevic, Snezana;
Hebeisen, Simon;
Kubisch, Christian;
Rebstock, Johannes;
Horvath, Steve;
Hallmann, Kerstin;
Dullinger, Joern S;
Rau, Birgit;
Haverkamp, Fritz;
Beyenburg, Stefan;
Schulz, Herbert;
Janz, Dieter;
Giese, Bernd;
Müller-Newen, Gerhard

Publication type:

Correction Notice

Characterization of SLCO5A1/OATP5A1, a Solute Carrier Transport Protein with Non-Classical Function.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083257

By:

Sebastian, Katrin;
Detro-Dassen, Silvia;
Rinis, Natalie;
Fahrenkamp, Dirk;
Müller-Newen, Gerhard;
Merk, Hans F.;
Schmalzing, Günther;
Zwadlo-Klarwasser, Gabriele;
Baron, Jens Malte

Publication type:

Article

MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis.

Published in:

FASEB Journal, 2015, v. 29, n. 11, p. 4497, doi. 10.1096/fj.15-273904

By:

Alampour-Rajabi, Setareh;
El Bounkari, Omar;
Rot, Antal;
Müller-Newen, Gerhard;
Bachelerie, Françoise;
Gawaz, Meinrad;
Weber, Christian;
Schober, Andreas;
Bernhagen, Jürgen

Publication type:

Article

Characterization of cyclin L1 as an immobile component of the splicing factor compartment.

Published in:

FASEB Journal, 2007, v. 21, n. 12, p. 3142, doi. 10.1096/fj.07-8377com

By:

Herrmann, Andreas;
Fleischer, Katrin;
Czajkowska, Hanna;
Müller-Newen, Gerhard;
Becker, Walter

Publication type:

Article

Mitochondrial 3-2trans-Enoyl-CoA Isomerase.

Published in:

Biological Chemistry, 1991, v. 372, n. 2, p. 613

By:

MÜLLER-NEWEN, Gerhard;
STOFFEL, Wilhelm

Publication type:

Article

Bow to your partner for signaling.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 6, p. 476, doi. 10.1038/nsmb0605-476

By:

Hermanns, Heike M;
Müller-Newen, Gerhard;
Heinrich, Peter C;
Haan, Serge

Publication type:

Article

Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00393

By:

Zechendorf, Elisabeth;
Vaßen, Phillip;
Zhang, Jieyi;
Hallawa, Ahmed;
Martincuks, Antons;
Krenkel, Oliver;
Müller-Newen, Gerhard;
Schuerholz, Tobias;
Simon, Tim-Philipp;
Marx, Gernot;
Ascheid, Gerd;
Schmeink, Anke;
Dartmann, Guido;
Thiemermann, Christoph;
Martin, Lukas

Publication type:

Article

Biofunctionalization of Dental Abutment Surfaces by Crosslinked ECM Proteins Strongly Enhances Adhesion and Proliferation of Gingival Fibroblasts.

Published in:

Advanced Healthcare Materials, 2021, v. 10, n. 10, p. 1, doi. 10.1002/adhm.202100132

By:

Palkowitz, Alena L.;
Tuna, Taskin;
Bishti, Shaza;
Böke, Frederik;
Steinke, Nathalie;
Müller‐Newen, Gerhard;
Wolfart, Stefan;
Fischer, Horst

Publication type:

Article

Dominant-negative activity of the STAT3-Y705F mutant depends on the N-terminal domain.

Published in:

Cell Communication & Signaling, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1478-811X-11-83

By:

Mohr, Anne;
Fahrenkamp, Dirk;
Rinis, Natalie;
Müller-Newen, Gerhard

Publication type:

Article

Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62.

Published in:

Cell Communication & Signaling, 2012, v. 10, n. 1, p. 28, doi. 10.1186/1478-811X-10-28

By:

Kleine, Henning;
Herrmann, Andreas;
Lamark, Trond;
Forst, Alexandra H.;
Verheugd, Patricia;
Lüscher-Firzlaff, Juliane;
Lippok, Barbara;
Feijs, Karla L. H.;
Herzog, Nicolas;
Kremmer, Elisabeth;
Johansen, Terje;
Müller-Newen, Gerhard;
Lüscher, Bernhard

Publication type:

Article

A receptor fusion protein for the inhibition of murine oncostatin M.

Published in:

BMC Biotechnology, 2011, v. 11, n. 1, p. 1, doi. 10.1186/1472-6750-11-3

By:

Brolund, Liv;
Küster, Andrea;
Korr, Sabrina;
Vogt, Michael;
Müller-Newen, Gerhard

Publication type:

Article

Intramolecular hydrophobic interactions are critical mediators of STAT5 dimerization.

Published in:

Scientific Reports, 2016, p. 35454, doi. 10.1038/srep35454

By:

Fahrenkamp, Dirk;
Li, Jinyu;
Ernst, Sabrina;
Schmitz-Van de Leur, Hildegard;
Chatain, Nicolas;
Küster, Andrea;
Koschmieder, Steffen;
Lüscher, Bernhard;
Rossetti, Giulia;
Müller-Newen, Gerhard

Publication type:

Article

Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery.

Published in:

Scientific Reports, 2015, p. 14685, doi. 10.1038/srep14685

By:

Görtz, Dieter;
Braun, Gerald S.;
Maruta, Yuichi;
Djudjaj, Sonja;
van Roeyen, Claudia R.;
Martin, Ina V.;
Küster, Andrea;
Schmitz-Van de Leur, Hildegard;
Scheller, Jürgen;
Ostendorf, Tammo;
Floege, Jürgen;
Müller-Newen, Gerhard

Publication type:

Article

The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum.

Published in:

Innate Immunity, 2016, v. 22, n. 8, p. 612, doi. 10.1177/1753425916667474

By:

Martin, Lukas;
Peters, Carsten;
Heinbockel, Lena;
Moellmann, Julia;
Martincuks, Antons;
Brandenburg, Klaus;
Lehrke, Michael;
Müller-Newen, Gerhard;
Marx, Gernot;
Schuerholz, Tobias

Publication type:

Article

Correction: Maranto et al. Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo. Cancers 2020, 12 , 3412.

Published in:

2025

By:

Maranto, Cristina;
Udhane, Vindhya;
Jia, Jing;
Verma, Ranjit;
Müller-Newen, Gerhard;
LaViolette, Peter S.;
Pereckas, Michael;
Sabharwal, Lavannya;
Terhune, Scott;
Pattabiraman, Nagarajan;
Njar, Vincent C. O.;
Imig, John D.;
Wang, Liang;
Nevalainen, Marja T.

Publication type:

Correction Notice

Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3412, doi. 10.3390/cancers12113412

By:

Maranto, Cristina;
Udhane, Vindhya;
Jia, Jing;
Verma, Ranjit;
Müller-Newen, Gerhard;
LaViolette, Peter S.;
Pereckas, Michael;
Sabharwal, Lavannya;
Terhune, Scott;
Pattabiraman, Nagarajan;
Njar, Vincent C.O.;
Imig, John D.;
Wang, Liang;
Nevalainen, Marja T.

Publication type:

Article

Nucleocytoplasmic Shuttling of STATs. A Target for Intervention?

Published in:

Cancers, 2019, v. 11, n. 11, p. 1815, doi. 10.3390/cancers11111815

By:

Ernst, Sabrina;
Müller-Newen, Gerhard

Publication type:

Article

Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses.

Published in:

Science Signaling, 2022, v. 15, n. 721, p. 1, doi. 10.1126/scisignal.abd9303

By:

Topolewski, Piotr;
Zakrzewska, Karolina E.;
Walczak, Jarosław;
Nienałtowski, Karol;
Müller-Newen, Gerhard;
Singh, Abhyudai;
Komorowski, Michał

Publication type:

Article

Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy.

Published in:

Journal of Hematology & Oncology, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13045-015-0152-2

By:

Schumacher, Anne;
Denecke, Bernd;
Braunschweig, Till;
Stahlschmidt, Jasmin;
Ziegler, Susanne;
Brandenburg, Lars-Ove;
Stope, Matthias B.;
Martincuks, Antons;
Vogt, Michael;
Görtz, Dieter;
Camporeale, Annalisa;
Poli, Valeria;
Müller-Newen, Gerhard;
Brümmendorf, Tim H.;
Ziegler, Patrick

Publication type:

Article

Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy

Published in:

Journal of Hematology & Oncology, 2015, v. 8, n. 1, p. 64, doi. 10.1186/s13045-015-0152-2

By:

Schumacher, Anne;
Denecke, Bernd;
Braunschweig, Till;
Stahlschmidt, Jasmin;
Ziegler, Susanne;
Brandenburg, Lars-Ove;
Stope, Matthias B.;
Martincuks, Antons;
Vogt, Michael;
Görtz, Dieter;
Camporeale, Annalisa;
Poli, Valeria;
Müller-Newen, Gerhard;
Brümmendorf, Tim H.;
Ziegler, Patrick

Publication type:

Article

Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms.

Published in:

Journal of Hematology & Oncology, 2014, v. 7, n. 1, p. 151, doi. 10.1186/s13045-014-0092-2

By:

Schneider, Rebekka K.;
Ziegler, Susanne;
Leisten, Isabelle;
Ferreira, Monica S. V.;
Schumacher, Anne;
Rath, Björn;
Fahrenkamp, Dirk;
Müller-Newen, Gerhard;
Crysandt, Martina;
Wilop, Stefan;
Jost, Edgar;
Koschmieder, Steffen;
Knüchel, Ruth;
Brümmendorf, Tim H.;
Ziegler, Patrick

Publication type:

Article

Development of platelets during steady state and inflammation.

Published in:

Journal of Leukocyte Biology, 2017, v. 101, n. 5, p. 1109, doi. 10.1189/jlb.1RU0916-391RR

By:

Müller‐Newen, Gerhard;
Stope, Matthias B.;
Kraus, Thomas;
Ziegler, Patrick

Publication type:

Article

Cellular uptake of fluorophore-labeled glyco-DNA-gold nanoparticles.

Published in:

Journal of Nanoparticle Research, 2013, v. 15, n. 10, p. 1, doi. 10.1007/s11051-013-1992-8

By:

Witten, Katrin;
Ruff, Julie;
Mohr, Anne;
Görtz, Dieter;
Recker, Tobias;
Rinis, Natalie;
Rech, Claudia;
Elling, Lothar;
Müller-Newen, Gerhard;
Simon, Ulrich

Publication type:

Article

Biological responses to PDGF-AA versus PDGF-CC in renal fibroblasts.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 4, p. 889, doi. 10.1093/ndt/gfs509

By:

Seikrit, Claudia;
Henkel, Corinna;
van Roeyen, Claudia R. C.;
Bokemeyer, Dirk;
Eitner, Frank;
Martin, Ina V.;
Boor, Peter;
Knüchel, Ruth;
Meyer, Helmut E.;
Müller-Newen, Gerhard;
Eriksson, Ulf;
Floege, Jürgen;
Ostendorf, Tammo

Publication type:

Article

Corrigendum: Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical- in-Silico Approach Combining In Vitro Experiments and Machine Learning.

Published in:

2020

By:

Zechendorf, Elisabeth;
Vaßen, Phillip;
Zhang, Jieyi;
Hallawa, Ahmed;
Martincuks, Antons;
Krenkel, Oliver;
Müller-Newen, Gerhard;
Schuerholz, Tobias;
Simon, Tim-Philipp;
Marx, Gernot;
Ascheid, Gerd;
Schmeink, Anke;
Dartmann, Guido;
Thiemermann, Christoph;
Martin, Lukas

Publication type:

Correction Notice

Soluble Receptors for Cytokines and Growth Factors.

Published in:

International Archives of Allergy & Immunology, 1996, v. 111, n. 2, p. 99, doi. 10.1159/000237353

By:

Müller-Newen, Gerhard;
Köhne, Christian;
Heinrich, Peter C.

Publication type:

Article

Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies.

Published in:

European Journal of Immunology, 1995, v. 25, n. 12, p. 3474, doi. 10.1002/eji.1830251240

By:

Wijdenes, John;
Heinrich, Peter C.;
Müller-Newen, Gerhard;
Roche, Catherine;
Gu, Zong-Jiang;
Clément, Claude;
Klein, Bernard

Publication type:

Article

Genetic barcoding reveals clonal dominance in iPSC-derived mesenchymal stromal cells.

Published in:

Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. 1, doi. 10.1186/s13287-020-01619-5

By:

Hollmann, Jonathan;
Brecht, Johanna;
Goetzke, Roman;
Franzen, Julia;
Selich, Anton;
Schmidt, Marco;
Eipel, Monika;
Ostrowska, Alina;
Hapala, Jan;
Fernandez-Rebollo, Eduardo;
Müller-Newen, Gerhard;
Rothe, Michael;
Eggermann, Thomas;
Zenke, Martin;
Wagner, Wolfgang

Publication type:

Article

Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.

Published in:

Cell Communication & Signaling, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12964-014-0081-7

By:

Fahrenkamp, Dirk;
de Leur, Hildegard Schmitz-Van;
Küster, Andrea;
Chatain, Nicolas;
Müller-Newen, Gerhard

Publication type:

Article

Intracellular signaling prevents effective blockade of oncogenic gp130 mutants by neutralizing antibodies.

Published in:

Cell Communication & Signaling, 2014, v. 12, n. 1, p. 1, doi. 10.1186/1478-811X-12-14

By:

Rinis, Natalie;
Küster, Andrea;
Schmitz-Van de Leur, Hildegard;
Mohr, Anne;
Müller-Newen, Gerhard

Publication type:

Article

Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix (Adv. Mater. 5/2024).

Published in:

Advanced Materials, 2024, v. 36, n. 5, p. 1, doi. 10.1002/adma.202470037

By:

De Lorenzi, Federica;
Hansen, Nadja;
Theek, Benjamin;
Daware, Rasika;
Motta, Alessandro;
Breuel, Saskia;
Nasehi, Ramin;
Baumeister, Julian;
Schöneberg, Jan;
Stojanović, Natalija;
von Stillfried, Saskia;
Vogt, Michael;
Müller‐Newen, Gerhard;
Maurer, Jochen;
Sofias, Alexandros Marios;
Lammers, Twan;
Fischer, Horst;
Kiessling, Fabian

Publication type:

Article

Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix.

Published in:

Advanced Materials, 2024, v. 36, n. 5, p. 1, doi. 10.1002/adma.202303196

By:

De Lorenzi, Federica;
Hansen, Nadja;
Theek, Benjamin;
Daware, Rasika;
Motta, Alessandro;
Breuel, Saskia;
Nasehi, Ramin;
Baumeister, Julian;
Schöneberg, Jan;
Stojanović, Natalija;
von Stillfried, Saskia;
Vogt, Michael;
Müller‐Newen, Gerhard;
Maurer, Jochen;
Sofias, Alexandros Marios;
Lammers, Twan;
Fischer, Horst;
Kiessling, Fabian

Publication type:

Article

Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix (Adv. Mater. 5/2024).

Published in:

Advanced Materials, 2024, v. 36, n. 5, p. 1, doi. 10.1002/adma.202470037

By:

De Lorenzi, Federica;
Hansen, Nadja;
Theek, Benjamin;
Daware, Rasika;
Motta, Alessandro;
Breuel, Saskia;
Nasehi, Ramin;
Baumeister, Julian;
Schöneberg, Jan;
Stojanović, Natalija;
von Stillfried, Saskia;
Vogt, Michael;
Müller‐Newen, Gerhard;
Maurer, Jochen;
Sofias, Alexandros Marios;
Lammers, Twan;
Fischer, Horst;
Kiessling, Fabian

Publication type:

Article

Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix.

Published in:

Advanced Materials, 2024, v. 36, n. 5, p. 1, doi. 10.1002/adma.202303196

By:

De Lorenzi, Federica;
Hansen, Nadja;
Theek, Benjamin;
Daware, Rasika;
Motta, Alessandro;
Breuel, Saskia;
Nasehi, Ramin;
Baumeister, Julian;
Schöneberg, Jan;
Stojanović, Natalija;
von Stillfried, Saskia;
Vogt, Michael;
Müller‐Newen, Gerhard;
Maurer, Jochen;
Sofias, Alexandros Marios;
Lammers, Twan;
Fischer, Horst;
Kiessling, Fabian

Publication type:

Article

Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 24, p. 17560, doi. 10.3390/ijms242417560

By:

Bermes, Max;
Rodriguez, Maria Jimena;
de Toledo, Marcelo Augusto Szymanski;
Ernst, Sabrina;
Müller-Newen, Gerhard;
Brümmendorf, Tim Henrik;
Chatain, Nicolas;
Koschmieder, Steffen;
Baumeister, Julian

Publication type:

Article

The signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology region.

Published in:

Protein Science: A Publication of the Protein Society, 1999, v. 8, n. 1, p. 5, doi. 10.1110/ps.8.1.5

By:

Kernebeck, Thomas;
Pflanz, Stefan;
Heinrich, Peter C.;
Wollmer, Axel;
Grötzinger, Joachim;
Müller-Newen, Gerhard;
Kurapkat, Günther;
Grzesiek, Stephan;
Scheek, Ruud M.;
Dijkstra, Klaas

Publication type:

Article

Latent MMP-9 is bound to TIMP-1 before secretion.

Published in:

Biological Chemistry, 2007, v. 388, n. 11, p. 1227, doi. 10.1515/BC.2007.123

By:

Roderfeld, Martin;
Graf, Jürgen;
Giese, Bernd;
Salguero-Palacios, Rebeca;
Tschuschner, Annette;
Müller-Newen, Gerhard;
Roeb, Elke

Publication type:

Article