Works by Mølhøj, Michael

Results: 15

Variable heavy–variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 289, doi. 10.1093/protein/gzy021

By:

Regula, Joerg Thomas;
Imhof-Jung, Sabine;
Mølhøj, Michael;
Benz, Joerg;
Ehler, Andreas;
Bujotzek, Alexander;
Schaefer, Wolfgang;
Klein, Christian

Publication type:

Article

A highly stable polyethylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration.

Published in:

PEDS: Protein Engineering, Design & Selection, 2006, v. 19, n. 10, p. 461, doi. 10.1093/protein/gzl031

By:

Krinner, Eva-Maria;
Hepp, Julia;
Hoffmann, Patrick;
Bruckmaier, Sandra;
Petersen, Laetitia;
Petsch, Silke;
Parr, Larissa;
Schuster, Ioana;
Mangold, Susanne;
Lorenczewski, Grit;
Lutterbüse, Petra;
Buziol, Stefan;
Hochheim, Inessa;
Volkland, Jörg;
Mølhøj, Michael;
Sriskandarajah, Mirnalini;
Strasser, Markus;
Itin, Christian;
Wolf, Andreas;
Basu, Amartya

Publication type:

Article

The biosynthesis of the branched-chain sugar D-apiose in plants: functional cloning and characterization of a UDP-D-apiose/UDP-D-xylose synthase from Arabidopsis.

Published in:

Plant Journal, 2003, v. 35, n. 6, p. 693

By:

Mølhøj, Michael;
Verma, Rajeev;
Reiter, Wolf-Dieter

Publication type:

Article

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.

Published in:

2019

By:

Sustmann, Claudio;
Dickopf, Steffen;
Regula, Jörg T.;
Kettenberger, Hubert;
Mølhøj, Michael;
Gassner, Christian;
Weininger, Diana;
Fenn, Sebastian;
Manigold, Tobias;
Kling, Lothar;
Künkele, Klaus-Peter;
Schwaiger, Manfred;
Bossenmaier, Birgit;
Griese, Julia J.;
Hopfner, Karl-Peter;
Graff-Meyer, Alexandra;
Stahlberg, Henning;
Ringler, Philippe;
Lauer, Matthias E.;
Brinkmann, Ulrich

Publication type:

Report

Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics.

Published in:

2019

By:

Tyshchuk, Oksana;
Gstöttner, Christoph;
Funk, Dennis;
Nicolardi, Simone;
Frost, Stefan;
Klostermann, Stefan;
Becker, Tim;
Jolkver, Elena;
Schumacher, Felix;
Koller, Claudia Ferrara;
Völger, Hans Rainer;
Wuhrer, Manfred;
Bulau, Patrick;
Mølhøj, Michael

Publication type:

Report

GingisKHAN™ protease cleavage allows a high-throughput antibody to Fab conversion enabling direct functional assessment during lead identification of human monoclonal and bispecific IgG1 antibodies.

Published in:

mAbs (1942-0862), 2017, v. 9, n. 7, p. 1076, doi. 10.1080/19420862.2017.1364325

By:

Moelleken, Jörg;
Endesfelder, Manuel;
Gassner, Christian;
Lingke, Sabine;
Tomaschek, Simone;
Tyshchuk, Oksana;
Lorenz, Stefan;
Reiff, Ulrike;
Mølhøj, Michael

Publication type:

Article

Detection of a phosphorylated glycine-serine linker in an IgG-based fusion protein.

Published in:

mAbs (1942-0862), 2017, v. 9, n. 1, p. 94, doi. 10.1080/19420862.2016.1236165

By:

Tyshchuk, Oksana;
Völger, Hans Rainer;
Ferrara, Claudia;
Bulau, Patrick;
Koll, Hans;
Mølhøj, Michael

Publication type:

Article

Heavy and light chain pairing of bivalent quadroma and knobs-into-holes antibodies analyzed by UHR-ESI-QTOF mass spectrometry.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 1, p. 49, doi. 10.1080/19420862.2015.1111498

By:

Schaefer, Wolfgang;
Völger, Hans R;
Lorenz, Stefan;
Imhof-Jung, Sabine;
Regula, Jörg T;
Klein, Christian;
Mølhøj, Michael

Publication type:

Article

Assessment of chemical modifications of sites in the CDRs of recombinant antibodies.

Published in:

mAbs (1942-0862), 2014, v. 6, n. 2, p. 327, doi. 10.4161/mabs.27876

By:

Haberger, Markus;
Bomans, Katrin;
Diepold, Katharina;
Hook, Michaela;
Gassner, Jana;
Schlothauer, Tilman;
Zwick, Adrian;
Spick, Christian;
Kepert, Jochen Felix;
Hienz, Brigitte;
Wiedmann, Michael;
Beck, Hermann;
Metzger, Philipp;
Mølhøj, Michael;
Knoblich, Constanze;
Grauschopf, Ulla;
Reusch, Dietmar;
Bulau, Patrick

Publication type:

Article

Towards Understanding the Role of Membrane-bound Endo-β-1,4-glucanases in Cellulose Biosynthesis.

Published in:

Plant & Cell Physiology, 2002, v. 43, n. 12, p. 1399

By:

Mølhøj, Michael;
Pagant, Silvère;
Höfte, Herman

Publication type:

Article

Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100736

By:

Sydow, Jasmin F.;
Lipsmeier, Florian;
Larraillet, Vincent;
Hilger, Maximiliane;
Mautz, Bjoern;
Mølhøj, Michael;
Kuentzer, Jan;
Klostermann, Stefan;
Schoch, Juergen;
Voelger, Hans R.;
Regula, Joerg T.;
Cramer, Patrick;
Papadimitriou, Apollon;
Kettenberger, Hubert

Publication type:

Article

Identification and Monitoring of Host Cell Proteins by Mass Spectrometry Combined with High Performance Immunochemistry Testing.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081639

By:

Bomans, Katrin;
Lang, Antje;
Roedl, Veronika;
Adolf, Lisa;
Kyriosoglou, Kyrillos;
Diepold, Katharina;
Eberl, Gabriele;
Mølhøj, Michael;
Strauss, Ulrike;
Schmalz, Christian;
Vogel, Rudolf;
Reusch, Dietmar;
Wegele, Harald;
Wiedmann, Michael;
Bulau, Patrick

Publication type:

Article

Simultaneous Assessment of Asp Isomerization and Asn Deamidation in Recombinant Antibodies by LC-MS following Incubation at Elevated Temperatures.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030295

By:

Diepold, Katharina;
Bomans, Katrin;
Wiedmann, Michael;
Zimmermann, Boris;
Petzold, Andreas;
Schlothauer, Tilman;
Mueller, Robert;
Moritz, Bernd;
Stracke, Jan Olaf;
Mølhøj, Michael;
Reusch, Dietmar;
Bulau, Patrick

Publication type:

Article

Leader sequences are not signal peptides.

Published in:

2004

By:

Mølhøj, Michael;
Degan, Florence Dal

Publication type:

Letter

Identification and characterization of a UDP-d-glucuronate 4-epimerase in Arabidopsis

Published in:

FEBS Letters, 2004, v. 569, n. 1-3, p. 327, doi. 10.1016/j.febslet.2004.06.005

By:

Usadel, Björn;
Schlüter, Urte;
Mølhøj, Michael;
Gipmans, Martijn;
Verma, Rajeev;
Kossmann, Jens;
Reiter, Wolf-Dieter;
Pauly, Markus

Publication type:

Article