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Incomplete Plasmodium falciparum growth inhibition following piperaquine treatment translates into increased parasite viability in the in vitro parasite reduction ratio assay.
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- Frontiers in Cellular & Infection Microbiology, 2024, p. 01, doi. 10.3389/fcimb.2024.1396786
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Antiprotozoal Activity of Plants Used in the Management of Sleeping Sickness in Angola and Bioactivity-Guided Fractionation of Brasenia schreberi J.F.Gmel and Nymphaea lotus L. Active against T. b. rhodesiense.
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- Molecules, 2024, v. 29, n. 7, p. 1611, doi. 10.3390/molecules29071611
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- Article
Phylogenetic Analysis of Pyruvate-Ferredoxin Oxidoreductase, a Redox Enzyme Involved in the Pharmacological Activation of Nitro-Based Prodrugs in Bacteria and Protozoa.
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- Biology (2079-7737), 2024, v. 13, n. 3, p. 178, doi. 10.3390/biology13030178
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- Article
Drug Repurposing in the Chemotherapy of Infectious Diseases.
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- Molecules, 2024, v. 29, n. 3, p. 635, doi. 10.3390/molecules29030635
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- Article
Induced pluripotent stem cell-derived human macrophages as an infection model for Leishmania donovani.
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- PLoS Neglected Tropical Diseases, 2024, v. 18, n. 1, p. 1, doi. 10.1371/journal.pntd.0011559
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- Article
Structure–Activity Relationships and Antiplasmodial Potencies of Novel 3,4-Disubstituted 1,2,5-Oxadiazoles.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14480, doi. 10.3390/ijms241914480
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- Article
Trypanosoma cruzi STIB980: A TcI Strain for Drug Discovery and Reverse Genetics.
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- Pathogens, 2023, v. 12, n. 10, p. 1217, doi. 10.3390/pathogens12101217
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- Article
Editorial Swiss TPH: 30 Years of R&D Towards New Drugs for Tropical Diseases.
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- Chimia, 2023, v. 77, n. 9, p. 570, doi. 10.2533/chimia.2023.570
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- Article
Repurposing Know-how for Drug Development: Case Studies from the Swiss Tropical and Public Health Institute.
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- Chimia, 2023, v. 77, n. 9, p. 582, doi. 10.2533/chimia.2023.582
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Key Contributions by the Swiss Tropical and Public Health Institute Towards New and Better Drugs for Tropical Diseases.
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- Chimia, 2023, v. 77, n. 9, p. 593, doi. 10.2533/chimia.2023.593
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- Article
Antiprotozoal activity of natural products from Nigerien plants used in folk medicine.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1190241
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- Article
The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Plasmodium falciparum Viability after Antimalarial Treatment In Vitro.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 2, p. 163, doi. 10.3390/ph16020163
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- Article
Synthesis and Antiprotozoal Activity of Azabicyclo-Nonane Pyrimidine Hybrids.
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- Molecules, 2023, v. 28, n. 1, p. 307, doi. 10.3390/molecules28010307
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- Article
Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership.
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- Diseases, 2022, v. 10, n. 4, p. 90, doi. 10.3390/diseases10040090
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New Derivatives of the Multi-Stage Active Malaria Box Compound MMV030666 and Their Antiplasmodial Potencies.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 12, p. 1503, doi. 10.3390/ph15121503
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- Article
Antiprotozoal Activity of Azabicyclo-Nonanes Linked to Tetrazole or Sulfonamide Cores.
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- Molecules, 2022, v. 27, n. 19, p. 6217, doi. 10.3390/molecules27196217
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- Article
Efficient Oxidative Dearomatisations of Substituted Phenols Using Hypervalent Iodine (III) Reagents and Antiprotozoal Evaluation of the Resulting Cyclohexadienones against T. b. rhodesiense and P. falciparum Strain NF54.
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- Molecules, 2022, v. 27, n. 19, p. 6559, doi. 10.3390/molecules27196559
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- Article
2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study.
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- Molecules, 2022, v. 27, n. 17, p. 5559, doi. 10.3390/molecules27175559
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Isolation and Structural Elucidation of Compounds from Pleiocarpa bicarpellata and Their In Vitro Antiprotozoal Activity.
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- Molecules, 2022, v. 27, n. 7, p. 2200, doi. 10.3390/molecules27072200
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Multi-insecticide resistant malaria vectors in the field remain susceptible to malathion, despite the presence of Ace1 point mutations.
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- PLoS Genetics, 2022, v. 18, n. 2, p. 1, doi. 10.1371/journal.pgen.1009963
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Laboratory Selection of Trypanosomatid Pathogens for Drug Resistance.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 2, p. 135, doi. 10.3390/ph15020135
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The 3-phosphoinositide–dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites.
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- PLoS Biology, 2021, v. 19, n. 12, p. 1, doi. 10.1371/journal.pbio.3001483
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Synthesis and Structure-Activity Relationships of New 2-Phenoxybenzamides with Antiplasmodial Activity.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 11, p. 1109, doi. 10.3390/ph14111109
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- Article
Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction.
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- Molecules, 2021, v. 26, n. 20, p. 6181, doi. 10.3390/molecules26206181
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- Article
8-Amino-6-Methoxyquinoline—Tetrazole Hybrids: Impact of Linkers on Antiplasmodial Activity.
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- Molecules, 2021, v. 26, n. 18, p. 5530, doi. 10.3390/molecules26185530
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- Article
Enantiospecific antitrypanosomal in vitro activity of eflornithine.
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- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 7, p. 1, doi. 10.1371/journal.pntd.0009583
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- Article
Antiprotozoische Struktur‐Aktivitäts‐Beziehungen von synthetischen Leucinostatin‐Derivaten und Aufklärung ihres Wirkprinzips.
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- Angewandte Chemie, 2021, v. 133, n. 28, p. 15741, doi. 10.1002/ange.202102153
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Rücktitelbild: Antiprotozoische Struktur‐Aktivitäts‐Beziehungen von synthetischen Leucinostatin‐Derivaten und Aufklärung ihres Wirkprinzips (Angew. Chem. 28/2021).
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- Angewandte Chemie, 2021, v. 133, n. 28, p. 15792, doi. 10.1002/ange.202104896
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Antiprotozoal Structure–Activity Relationships of Synthetic Leucinostatin Derivatives and Elucidation of their Mode of Action.
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- Angewandte Chemie International Edition, 2021, v. 60, n. 28, p. 15613, doi. 10.1002/anie.202102153
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Back Cover: Antiprotozoal Structure–Activity Relationships of Synthetic Leucinostatin Derivatives and Elucidation of their Mode of Action (Angew. Chem. Int. Ed. 28/2021).
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- Angewandte Chemie International Edition, 2021, v. 60, n. 28, p. 15660, doi. 10.1002/anie.202104896
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- Article
Niclosamide Is Active In Vitro against Mycetoma Pathogens.
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- Molecules, 2021, v. 26, n. 13, p. 4005, doi. 10.3390/molecules26134005
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Boswellic Acids Show In Vitro Activity against Leishmania donovani.
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- Molecules, 2021, v. 26, n. 12, p. 3651, doi. 10.3390/molecules26123651
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Antiprotozoal Nor -Triterpene Alkaloids from Buxus sempervirens L.
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- Antibiotics (2079-6382), 2021, v. 10, n. 6, p. 696, doi. 10.3390/antibiotics10060696
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Salvia officinalis L.: Antitrypanosomal Activity and Active Constituents against Trypanosoma brucei rhodesiense.
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- Molecules, 2021, v. 26, n. 11, p. 3226, doi. 10.3390/molecules26113226
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New Acyl Derivatives of 3-Aminofurazanes and Their Antiplasmodial Activities.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 5, p. 412, doi. 10.3390/ph14050412
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- Article
Combination With Tomatidine Improves the Potency of Posaconazole Against Trypanosoma cruzi.
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- Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fcimb.2021.617917
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The Alkaloid-Enriched Fraction of Pachysandra terminalis (Buxaceae) Shows Prominent Activity against Trypanosoma brucei rhodesiense.
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- Molecules, 2021, v. 26, n. 3, p. 591, doi. 10.3390/molecules26030591
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HPLC-Based Activity Profiling for Antiprotozoal Compounds in Croton gratissimus and Cuscuta hyalina.
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- Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01246
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Non-invasive monitoring of drug action: A new live in vitro assay design for Chagas' disease drug discovery.
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- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008487
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- Article
Lignans, Amides, and Saponins from Haplophyllum tuberculatum and Their Antiprotozoal Activity.
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- Molecules, 2020, v. 25, n. 12, p. 2825, doi. 10.3390/molecules25122825
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Mining Sudanese Medicinal Plants for Antiprotozoal Agents.
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- Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00865
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- Article
Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay.
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- Malaria Journal, 2019, v. 18, n. 1, p. 1, doi. 10.1186/s12936-019-3056-8
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- Article
Expression of a specific variant surface glycoprotein has a major impact on suramin sensitivity and endocytosis in Trypanosoma brucei.
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- FASEB Bioadvances, 2019, v. 1, n. 10, p. 595, doi. 10.1096/fba.2019-00033
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- Article
Cell Penetration, Herbicidal Activity, and in‐vivo‐Toxicity of Oligo‐Arginine Derivatives and of Novel Guanidinium‐Rich Compounds Derived from the Biopolymer Cyanophycin.
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- Helvetica Chimica Acta, 2018, v. 101, n. 10, p. N.PAG, doi. 10.1002/hlca.201800112
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Transporters of <italic>Trypanosoma brucei</italic>—phylogeny, physiology, pharmacology.
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- FEBS Journal, 2018, v. 285, n. 6, p. 1012, doi. 10.1111/febs.14302
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Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei.
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- Molecular Microbiology, 2018, v. 107, n. 1, p. 57, doi. 10.1111/mmi.13854
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Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei.
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- PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0188219
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Cherchez l'Electron.
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- Molecular Microbiology, 2017, v. 106, n. 2, p. 183, doi. 10.1111/mmi.13773
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Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity.
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- PLoS Pathogens, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.ppat.1006307
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In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate.
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- Malaria Journal, 2017, v. 16, p. 1, doi. 10.1186/s12936-017-1696-0
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- Article