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Effects of C-peptide on isolated human pancreatic islet cells.
Published in:
Diabetes/Metabolism Research & Reviews, 2007, v. 23, n. 3, p. 215, doi. 10.1002/dmrr.674
By:
- Bugliani, Marco;
- Torri, Scilla;
- Lupi, Roberto;
- Del Guerra, Silvia;
- Grupillo, Maria;
- Del Chiaro, Marco;
- Mosca, Franco;
- Boggi, Ugo;
- Del Prato, Stefano;
- Marchetti, Piero
Publication type:
Article
Improved insulin secretory function and reduced chemotactic properties after tissue culture of islets from type 1 diabetic patients.
Published in:
Diabetes/Metabolism Research & Reviews, 2004, v. 20, n. 3, p. 246, doi. 10.1002/dmrr.460
By:
- Lupi, Roberto;
- Marselli, Lorella;
- Dionisi, Sabrina;
- Del Guerra, Silvia;
- Boggi, Ugo;
- Del Chiaro, Marco;
- Lencioni, Cristina;
- Bugliani, Marco;
- Mosca, Franco;
- Di Mario, Umberto;
- Del Prato, Stefano;
- Dotta, Francesco;
- Marchetti, Piero
Publication type:
Article
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 8, p. 2155, doi. 10.1172/JCI30706
By:
- Lyssenko, Valeriya;
- Lupi, Roberto;
- Marchetti, Piero;
- Del Guerra, Silvia;
- Orho-Melander, Marju;
- Almgren, Peter;
- Sjögren, Marketa;
- Ling, Charlotte;
- Eriksson, Karl-Fredrik;
- Lethagen, Åsa-Linda;
- Mancarella, Rita;
- Berglund, Göran;
- Tuomi, Tiinamaija;
- Nilsson, Peter;
- Del Prato2, Stefano;
- Groop, Leif
Publication type:
Article
Nesidioblastosis and Insulinoma: A Rare Coexistence and a Therapeutic Challenge.
Published in:
Frontiers in Endocrinology, 2020, v. 10, p. 1, doi. 10.3389/fendo.2020.00010
By:
- Dardano, Angela;
- Daniele, Giuseppe;
- Lupi, Roberto;
- Napoli, Niccolò;
- Campani, Daniela;
- Boggi, Ugo;
- Del Prato, Stefano;
- Miccoli, Roberto
Publication type:
Article
Altered Insulin Receptor Signalling and β-Cell Cycle Dynamics in Type 2 Diabetes Mellitus.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0028050
By:
- Folli, Franco;
- Okada, Terumasa;
- Perego, Carla;
- Gunton, Jenny;
- Chong Wee Liew;
- Akiyama, Masaru;
- D'Amico, Anna;
- La Rosa, Stefano;
- Placidi, Claudia;
- Lupi, Roberto;
- Marchetti, Piero;
- Sesti, Giorgio;
- Hellerstein, Marc;
- Perego, Lucia;
- Kulkarni, Rohit N.
Publication type:
Article
Calpain-10 Expression Is Elevated in Pancreatic Islets from Patients with Type 2 Diabetes.
Published in:
PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006558
By:
- Charlotte Ling;
- Groop, Leif;
- Del Guerra, Silvia;
- Lupi, Roberto
Publication type:
Article
Pancreatic Islets from Type 2 Diabetic Patients Have Functional Defects and Increased Apoptosis That Are Ameliorated by Metformin.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 11, p. 5535, doi. 10.1210/jc.2004-0150
By:
- MARCHETTI, PIERO;
- DEL GUERRA, SILVIA;
- MARSELLI, LORELLA;
- LUPI, ROBERTO;
- MASINI, MATILDE;
- POLLERA, MARIA;
- BUGLIANI, MARCO;
- BOGGI, UGO;
- VISTOLI, FABIO;
- MOSCA, FRANCO;
- DEL PRATO, STEFANO
Publication type:
Article
Th2 Cytokines Have a Partial, Direct Protective Effect on the Function and Survival of Isolated Human Islets Exposed to Combined Proinflammatory and Th1 Cytokines.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 2, p. 4974, doi. 10.1210/jcem.86.10.7938
By:
- MARSELLI, LORELLA;
- DOTTA, FRANCESCO;
- PIRO, SALVATORE;
- SANTANGELO, CARMELA;
- MASINI, MATILDE;
- LUPI, ROBERTO;
- REALACCI, MASSIMO;
- GUERRA, SILVIA DEL;
- MOSCA, FRANCO;
- BOGGI, UGO;
- PURRELLO, FRANCESCO;
- NAVALESI, RENZO;
- MARCHETTI, PIERO
Publication type:
Article
Characterization of sulfonylurea receptors in isolated human pancreatic islets.
Published in:
Journal of Cellular Biochemistry, 1998, v. 71, n. 2, p. 182, doi. 10.1002/(SICI)1097-4644(19981101)71:2<182::AID-JCB4>3.0.CO;2-R
By:
- Giannaccini, Gino;
- Lupi, Roberto;
- Trincavelli, M. Letizia;
- Navalesi, Renzo;
- Betti, Laura;
- Marchetti, Piero;
- Lucacchini, Antonio;
- Guerra, Silvia Del;
- Martini, Claudia
Publication type:
Article
Peripheral benzodiazepine receptors in isolated human pancreatic islets.
Published in:
Journal of Cellular Biochemistry, 1997, v. 64, n. 2, p. 273, doi. 10.1002/(SICI)1097-4644(199702)64:2<273::AID-JCB10>3.0.CO;2-K
By:
- Giusti, Laura;
- Marchetti, Piero;
- Trincavelli, Letizia;
- Lupi, Roberto;
- Martini, Claudia;
- Lucacchini, Antonio;
- Guerra, Silvia Del;
- Tellini, Cristina;
- Carmellini, Mario;
- Navalesi, Renzo
Publication type:
Article
The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.
Published in:
European Journal of Endocrinology, 2006, v. 154, n. 2, p. 355, doi. 10.1530/eje.1.02086
By:
- Roberto Lupi
Publication type:
Article
The role of peripheral benzodiazepine receptors on the function and survival of isolated human pancreatic islets.
Published in:
European Journal of Endocrinology, 2004, v. 151, n. 2, p. 0207
By:
- Lorella Marselli;
- Letizia Trincavelli;
- Carmela Santangelo;
- Roberto Lupi;
- Silvia Del Guerra;
- Ugo Boggi;
- Alessandra Falleni;
- Vittorio Gremigni;
- Franco Mosca;
- Claudia Martini;
- Francesco Dotta;
- Umberto Di Mario;
- Stefano Del Prato;
- Piero Marchetti
Publication type:
Article
Hepatitis C virus infection and human pancreatic beta-cell dysfunction.
Published in:
2005
By:
- Masini, Matilde;
- Campani, Daniela;
- Boggi, Ugo;
- Menicagli, Michele;
- Funel, Nicola;
- Pollera, Maria;
- Lupi, Roberto;
- Del Guerra, Silvia;
- Bugliani, Marco;
- Torri, Scilla;
- Del Prato, Stefano;
- Mosca, Franco;
- Filipponi, Franco;
- Marchetti, Piero
Publication type:
journal article
Function of pancreatic islets isolated from a type 1 diabetic patient.
Published in:
2000
By:
- MARCHETTI, PIERO;
- DOTTA, FRANCESCO;
- ZHIDONG LING;
- LUPI, ROBERTO;
- DEL GUERRA, SILVIA;
- SANTANGELO, CARMELA;
- REALACCI, MASSIMO;
- MARSELLI, LORELLA;
- DI MARIO, UMBERTO;
- NAVALESI, RENZO;
- Marchetti, P;
- Dotta, F;
- Ling, Z;
- Lupi, R;
- Del Guerra, S;
- Santangelo, C;
- Realacci, M;
- Marselli, L;
- Di Mario, U;
- Navalesi, R
Publication type:
Case Study
Effects of Therapeutical Concentration of Immunosuppressant Drugs on Isolated Human Pancreatic Islets: Functional and Molecular Studies.
Published in:
Diabetes, 2007, v. 56, p. A718
By:
- Bugliani, Marco;
- Masini, Matilde;
- Torri, Scilla;
- Lupi, Roberto;
- Del Guerra, Silvia;
- Mancarella, Rita;
- Vistoli, Fabio;
- Del Chiaro, Marco;
- Del Prato, Stefano;
- Boggi, Ugo;
- Mosca, Franco;
- Marchetti, Piero
Publication type:
Article
G-Protein-Coupled Receptor 40 (gpr40) Expression in Human Pancreatic Islets: Regulation by Glucose, Fatty Acids and Type 2 Diabetes.
Published in:
Diabetes, 2007, v. 56, p. A442
By:
- Lupi, Roberto;
- Mancarella, Rita;
- Del Guerra, Silvia;
- Bugliani, Marco;
- Torri, Scilla;
- Galli, Martina;
- D'aleo, Valentina;
- Boggi, Ugo;
- Mosca, Franco;
- Del Prato, Stefano;
- Marchetti, Piero
Publication type:
Article
Pancreatic Beta Cell Altered Autophagy in Human Type 2 Diabetes (T2DM).
Published in:
Diabetes, 2007, v. 56, p. A413
By:
- Masini, Matilde;
- Bugliani, Marco;
- Marselli, Lorella;
- Lupi, Roberto;
- del Guerra, Silvia;
- Torri, Scilla;
- Grupillo, Maria;
- Mancarella, Rita;
- del Prato, Stefano;
- Pollera, Maria;
- Marchetti, Piero
Publication type:
Article
Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?
Published in:
2005
By:
- Welsh, Nils;
- Cnop, Miriam;
- Kharroubi, Ilham;
- Bugliani, Marco;
- Lupi, Roberto;
- Marchetti, Piero;
- Eizirik, Décio L.;
- Eizirik, Décio L
Publication type:
journal article
Functional and molecular defects of pancreatic islets in human type 2 diabetes.
Published in:
2005
By:
- Del Guerra, Silvia;
- Lupi, Roberto;
- Marselli, Lorella;
- Masini, Matilde;
- Bugliani, Marco;
- Sbrana, Simone;
- Torri, Scilla;
- Pollera, Maria;
- Boggi, Ugo;
- Mosca, Franco;
- Del Prato, Stefano;
- Marchetti, Piero
Publication type:
journal article
Prolonged in vitro exposure to autoantibodies against CD38 impairs the function and survival of human pancreatic islets.
Published in:
2002
By:
- Marchetti, Piero;
- Antonelli, Alessandro;
- Lupi, Roberto;
- Marselli, Lorella;
- Fallahi, Poupak;
- Nesti, Claudia;
- Baj, Germano;
- Ferrannini, Ele
Publication type:
journal article
Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism.
Published in:
2002
By:
- Marchetti, Piero;
- Lupi, Roberto;
- Federici, Massimo;
- Marselli, Lorella;
- Masini, Matilde;
- Boggi, Ugo;
- Del Guerra, Silvia;
- Patanè, Giovanni;
- Piro, Salvatore;
- Anello, Marcello;
- Bergamini, Ettore;
- Purrello, Francesco;
- Lauro, Renato;
- Mosca, Franco;
- Sesti, Giorgio;
- Del Prato, Stefano;
- Patanè, Giovanni
Publication type:
journal article
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
Published in:
2002
By:
- Lupi, Roberto;
- Dotta, Francesco;
- Marselli, Lorella;
- Guerra, Silvia Del;
- Masini, Matilde;
- Santangelo, Carmela;
- Patané, Giovanni;
- Boggi, Ugo;
- Piro, Salvatore;
- Anello, Marcello;
- Bergamini, Ettore;
- Mosca, Franco;
- Mario, Umberto Di;
- Prato, Stefano Del;
- Marchetti, Piero;
- Del Guerra, Silvia;
- Patané, Giovanni;
- Di Mario, Umberto;
- Del Prato, Stefano
Publication type:
journal article
Lipotoxicity in human pancreatic islets and the protective effect of metformin.
Published in:
2002
By:
- Lupi, Roberto;
- Del Guerra, Silvia;
- Fierabracci, Vanna;
- Marselli, Lorella;
- Novelli, Michela;
- Patanè, Giovanni;
- Boggi, Ugo;
- Mosca, Franco;
- Piro, Salvatore;
- Del Prato, Stefano;
- Marchetti, Piero;
- Patanè, Giovanni
Publication type:
journal article
Autoantibodies to CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in Caucasian patients with diabetes: effects on insulin release from human islets.
Published in:
1999
By:
- Pupilli, Cinzia;
- Giannini, Stefano;
- Marchetti, Piero;
- Lupi, Roberto;
- Antonelli, Alessandro;
- Malavasi, Fabio;
- Takasawa, Shin;
- Okamoto, Hiroshi;
- Ferrannini, Ele;
- Pupilli, C;
- Giannini, S;
- Marchetti, P;
- Lupi, R;
- Antonelli, A;
- Malavasi, F;
- Takasawa, S;
- Okamoto, H;
- Ferrannini, E
Publication type:
journal article
Cx36 makes channels coupling human pancreatic β-cells, and correlates with insulin expression.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 3, p. 428, doi. 10.1093/hmg/ddn370
By:
- Serre-Beinier, Véronique;
- Bosco, Domenico;
- Zulianello, Laurence;
- Charollais, Anne;
- Caille, Dorothée;
- Charpantier, Eric;
- Gauthier, Benoit R.;
- Diaferia, Giuseppe R.;
- Giepmans, Ben N.;
- Lupi, Roberto;
- Marchetti, Piero;
- Deng, Shaoping;
- Buhler, Léo;
- Berney, Thierry;
- Cirulli, Vincenzo;
- Meda, Paolo
Publication type:
Article
The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.
Published in:
Human Molecular Genetics, 2008, v. 17, n. 4, p. 478
By:
- Brun, Thierry;
- He, Kai Hui Hu;
- Lupi, Roberto;
- Boehm, Bernhard;
- Wojtusciszyn, Anne;
- Sauter, Nadine;
- Donath, Marc;
- Marchetti, Piero;
- Maedler, Kathrin;
- Gauthier, Benoit R.
Publication type:
Article
Goals of treatment for type 2 diabetes: beta-cell preservation for glycemic control.
Published in:
2009
By:
- Marchetti P;
- Lupi R;
- Del Guerra S;
- Bugliani M;
- D'Aleo V;
- Occhipinti M;
- Boggi U;
- Marselli L;
- Masini M;
- Marchetti, Piero;
- Lupi, Roberto;
- Del Guerra, Silvia;
- Bugliani, Marco;
- D'Aleo, Valentina;
- Occhipinti, Margherita;
- Boggi, Ugo;
- Marselli, Lorella;
- Masini, Matilde
Publication type:
journal article
Goals of Treatment for Type 2 Diabetes.
Published in:
Diabetes Care, 2009, v. 32, p. S178, doi. 10.2337/dc09-S306
By:
- Marchetti, Piero;
- Lupi, Roberto;
- Del Guerra, Silvia;
- Bugliani, Marco;
- D'Aleo, Valentina;
- Occhipinti, Margherita;
- Boggi, Ugo;
- Marselli, Lorella;
- Masini, Matilde
Publication type:
Article
Metabolic regulation of GLP-1 and PC1/3 in pancreatic α-cell line.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187836
By:
- Sancho, Veronica;
- Daniele, Giuseppe;
- Lucchesi, Daniela;
- Lupi, Roberto;
- Ciccarone, Annamaria;
- Penno, Giuseppe;
- Bianchi, Cristina;
- Dardano, Angela;
- Miccoli, Roberto;
- Del Prato, Stefano
Publication type:
Article
Beta-cell failure in type 2 diabetes mellitus.
Published in:
2008
By:
- Lencioni C;
- Lupi R;
- Del Prato S;
- Lencioni, Cristina;
- Lupi, Roberto;
- Del Prato, Stefano
Publication type:
journal article
β-cell failure in type 2 diabetes mellitus.
Published in:
Current Diabetes Reports, 2008, v. 8, n. 3, p. 179, doi. 10.1007/s11892-008-0031-0
By:
- Lencioni, Cristina;
- Lupi, Roberto;
- Prato, Stefano
Publication type:
Article
Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.
Published in:
2009
By:
- Cunha DA;
- Ladrière L;
- Ortis F;
- Igoillo-Esteve M;
- Gurzov EN;
- Lupi R;
- Marchetti P;
- Eizirik DL;
- Cnop M;
- Cunha, Daniel A;
- Ladrière, Laurence;
- Ortis, Fernanda;
- Igoillo-Esteve, Mariana;
- Gurzov, Esteban N;
- Lupi, Roberto;
- Marchetti, Piero;
- Eizirik, Décio L;
- Cnop, Miriam
Publication type:
journal article
Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB.
Published in:
Diabetes, 2009, v. 58, n. 12, p. 2851, doi. 10.2337/db09-0685
By:
- Cunha, Daniel A.;
- Ladrière, Laurence;
- Ortis, Fernanda;
- Igoillo-Esteve, Mariana;
- Gurzov, Esteban N.;
- Lupi, Roberto;
- Marchetti, Piero;
- Eizirik, Décio L.;
- Cnop, Miriam
Publication type:
Article

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